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2020

The position of the target site for engineered nucleases improves the aberrant mRNA clearance in in vivo genome editing

Lee, J. H., Yu, S., Nam, T. W., Roh, J. I., Jin, Y., Han, J. P., Cha, J. Y., Kim, Y. K., Yeom, S. C., Nam, K. T. & Lee, H. W., 2020 Dec 1, In : Scientific reports. 10, 1, 4173.

Research output: Contribution to journalArticle

Open Access
2019

Commensal-derived metabolites govern Vibrio cholerae pathogenesis in host intestine

You, J. S., Yong, J. H., Kim, G. H., Moon, S., Nam, K. T., Ryu, J. H., Yoon, M. Y. & Yoon, S. S., 2019 Sep 14, In : Microbiome. 7, 1, 132.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Development of novel biocompatible thermosensitive anti-adhesive agents using human-derived acellular dermal matrix

Jeong, J. J., Lee, D. W., Song, S. Y., Park, Y., Kim, J. H., Kim, J. I., Kim, H. G., Nam, K. T., Lee, W. J., Nam, K. H. & Lee, J. H., 2019 Feb, In : PloS one. 14, 2, e0212583.

Research output: Contribution to journalArticle

Open Access

Di-2-ethylhexylphthalate promotes thyroid cell proliferation and DNA damage through activating thyrotropin-receptor-mediated pathways in vitro and in vivo

Kim, S., Park, G. Y., Yoo, Y. J., Jeong, J. S., Nam, K. T., Jee, S. H., Lim, K. M. & Lee, Y. S., 2019 Feb, In : Food and Chemical Toxicology. 124, p. 265-272 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Enrichment of short-chain ceramides and free fatty acids in the skin epidermis, liver, and kidneys of db/db mice, a type 2 diabetes mellitus model

Kim, M., Jeong, H., Lee, B., Cho, Y., Yoon, W. K., Cho, A., Kwon, G., Nam, K. T., Ha, H. & Lim, K. M., 2019 Sep, In : Biomolecules and Therapeutics. 27, 5, p. 457-465 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: Possible involvement of ER stress and S6K1 activation

Lee, D. H., Lee, B., Park, J. S., Lee, Y. S., Kim, J. H., Cho, Y., Jo, Y., Kim, H. S., Lee, Y. H., Nam, K. T. & Bae, S. H., 2019 Jan 1, In : BMB reports. 52, 3, p. 190-195 6 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Intrinsic expression of viperin regulates thermogenesis in adipose tissues

Eom, J., Kim, J. J., Yoon, S. G., Jeong, H., Son, S., Lee, J. B., Yoo, J., Seo, H. J., Cho, Y., Kim, K. S., Choi, K. M., Kim, I. Y., Lee, H. Y., Nam, K. T., Cresswell, P., Seong, J. K. & Seo, J. Y., 2019 Aug 27, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17419-17428 10 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach

Li, X., Yu, S., Lee, Y., Guo, T., Kwon, N., Lee, D., Yeom, S. C., Cho, Y., Kim, G., Huang, J. D., Choi, S., Nam, K. T. & Yoon, J., 2019 Jan 23, In : Journal of the American Chemical Society. 141, 3, p. 1366-1372 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Knockdown of pyruvate kinase M2 inhibits cell proliferation, metabolism, and migration in renal cell carcinoma

Dey, P., Son, J. Y., Kundu, A., Kim, K. S., Lee, Y., Yoon, K., Yoon, S., Lee, B. M., Nam, K. T. & Kim, H. S., 2019 Nov 2, In : International journal of molecular sciences. 20, 22, 5622.

Research output: Contribution to journalArticle

Open Access

Loss of Rab25 promotes the development of skin squamous cell carcinoma through the dysregulation of integrin trafficking

Jeong, H., Lim, K. M., Kim, K. H., Cho, Y., Lee, B., Knowles, B. C., Roland, J. T., Zwerner, J. P., Goldenring, J. R. & Nam, K. T., 2019 Oct 1, In : Journal of Pathology. 249, 2, p. 227-240 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Lysates of a probiotic, lactobacillus rhamnosus, can improve skin barrier function in a reconstructed human epidermis model

Jung, Y. O., Jeong, H., Cho, Y., Lee, E. O., Jang, H. W., Kim, J., Nam, K. T. & Lim, K. M., 2019 Sep 1, In : International journal of molecular sciences. 20, 17, 4289.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Rab25 deficiency perturbs epidermal differentiation and skin barrier function in mice

Jeong, H., Lim, K. M., Goldenring, J. R. & Nam, K. T., 2019 Jan 1, In : Biomolecules and Therapeutics. 27, 6, p. 553-561 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

RAE1 mediated ZEB1 expression promotes epithelial–mesenchymal transition in breast cancer

Oh, J. H., Lee, J. Y., Yu, S., Cho, Y., Hur, S., Nam, K. T. & Kim, M. H., 2019 Dec 1, In : Scientific reports. 9, 1, 2977.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Sequential Protein-Responsive Nanophotosensitizer Complex for Enhancing Tumor-Specific Therapy

Li, X., Fan, H., Guo, T., Bai, H., Kwon, N., Kim, K. H., Yu, S., Cho, Y., Kim, H., Nam, K. T., Yoon, J., Zhang, X. B. & Tan, W., 2019 Jun 25, In : ACS Nano. 13, 6, p. 6702-6710 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Sexually dimorphic leanness and hypermobility in p16Ink4a/CDKN2A-deficient mice coincides with phenotypic changes in the cerebellum

Kim, K. H., Cho, Y., Lee, J., Jeong, H., Lee, Y., Kim, S. I., Kim, C. H., Lee, H. W. & Nam, K. T., 2019 Aug 1, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

ChREBP deficiency leads to diarrhea-predominant irritable bowel syndrome

Oh, A. R., Sohn, S., Lee, J., Park, J. M., Nam, K. T., Hahm, K. B., Kim, Y. B., Lee, H. J. & Cha, J. Y., 2018 Aug, In : Metabolism: Clinical and Experimental. 85, p. 286-297 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Discovery of Ezrin Expression as a Potential Biomarker for Chemically Induced Ocular Irritation Using Human Corneal Epithelium Cell Line and a Reconstructed Human Cornea-like Epithelium Model

Ye, D. J., Kwon, Y. J., Baek, H. S., Shin, S., Lee, C., Yun, J. W., Nam, K. T., Lim, K. M. & Chun, Y. J., 2018 Oct 1, In : Toxicological Sciences. 165, 2, p. 335-346 12 p.

Research output: Contribution to journalArticle

Expression of LRIG1, a Negative Regulator of EGFR, Is Dynamically Altered during Different Stages of Gastric Carcinogenesis

Yu, S., Yang, M., Lim, K. M., Cho, Y., Kim, H., Lee, K., Jeong, S. H., Coffey, R. J., Goldenring, J. R. & Nam, K. T., 2018 Dec, In : American Journal of Pathology. 188, 12, p. 2912-2923 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Ezrin as a complementary marker in ocular toxicity assessment using a three-dimensional reconstructed human corneal-like epithelium model, EpiOcular™

Ko, K. Y., Hong, M. H., Kim, T. S., Nam, K. T., Lee, G. Y., Yi, J. S., Ahn, I. Y., Kim, J. H. & Lee, J. K., 2018 Jul, In : Journal of Pharmacological and Toxicological Methods. 92, p. 24-33 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Facile Supramolecular Approach to Nucleic-Acid-Driven Activatable Nanotheranostics That Overcome Drawbacks of Photodynamic Therapy

Li, X., Yu, S., Lee, D., Kim, G., Lee, B., Cho, Y., Zheng, B. Y., Ke, M. R., Huang, J. D., Nam, K. T., Chen, X. & Yoon, J., 2018 Jan 23, In : ACS Nano. 12, 1, p. 681-688 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

High-resolution acoustophoretic 3D cell patterning to construct functional collateral cylindroids for ischemia therapy

Kang, B., Shin, J., Park, H. J., Rhyou, C., Kang, D., Lee, S. J., Yoon, Y. S., Cho, S. W. & Lee, H., 2018 Dec 1, In : Nature communications. 9, 1, 5402.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Investigation of dermal toxicity of ionic liquids in monolayer-cultured skin cells and 3D reconstructed human skin models

Hwang, J. H., Park, H., Choi, D. W., Nam, K. T. & Lim, K. M., 2018 Feb, In : Toxicology in Vitro. 46, p. 194-202 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Low dose exposure to Di-2-ethylhexylphthalate in Juvenile rats alters the expression of genes related with thyroid hormone regulation

Kim, M., Jeong, J. S., Kim, H., Hwang, S., Park, I. H., Lee, B. C., Yoon, S. I., Jee, S. H., Nam, K. T. & Lim, K. M., 2018 Sep, In : Biomolecules and Therapeutics. 26, 5, p. 512-519 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Nanomatrix Coated Stent Enhances Endothelialization but Reduces Platelet, Smooth Muscle Cell, and Monocyte Adhesion under Physiologic Conditions

Alexander, G. C., Hwang, P. T. J., Chen, J., Kim, J., Brott, B. C., Yoon, Y. S. & Jun, H. W., 2018 Jan 8, In : ACS Biomaterials Science and Engineering. 4, 1, p. 107-115 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Neuronal Nitric Oxide Synthase Is a Novel Biomarker for the Interstitial Cells of Cajal in Stress-Induced Diarrhea-Dominant Irritable Bowel Syndrome

Jang, D. E., Bae, J. H., Chang, Y. J., Lee, Y. H., Nam, K. T., Kim, I. Y., Seong, J. K., Lee, Y. C. & Yeom, S. C., 2018 Mar 1, In : Digestive diseases and sciences. 63, 3, p. 619-627 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Direct Reprogramming of Human Dermal Fibroblasts into Endothelial Cells Using ER71/ETV2

Lee, S., Park, C., Han, J. W., Kim, J. Y., Cho, K., Kim, E. J., Kim, S., Lee, S. J., Oh, S. Y., Tanaka, Y., Park, I. H., An, H. J., Shin, C. M., Sharma, S. & Yoon, Y. S., 2017 Mar 3, In : Circulation Research. 120, 5, p. 848-861 14 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Enhanced therapeutic and long-term dynamic vascularization effects of human pluripotent stem cell-derived endothelial cells encapsulated in a nanomatrix gel

Lee, S. J., Sohn, Y. D., Andukuri, A., Kim, S., Byun, J., Han, J. W., Park, I. H., Jun, H. W. & Yoon, Y. S., 2017 Jan 1, In : Circulation. 136, 20, p. 1939-1954 16 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Evaluation of ocular irritancy of coal-tar dyes used in cosmetics employing reconstructed human cornea-like epithelium and short time exposure tests

Lee, M., Nam, K. T., Kim, J., Lim, S. E., Yeon, S. H., Lee, B., Lee, J. Y. & Lim, K. M., 2017 Oct, In : Food and Chemical Toxicology. 108, p. 236-243 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Expression levels of GABA-A receptor subunit alpha 3, Gabra3 and lipoprotein lipase, Lpl are associated with the susceptibility to acetaminophen-induced hepatotoxicity

Kim, M., Yun, J. W., Shin, K., Cho, Y., Yang, M., Nam, K. T. & Lim, K. M., 2017 Mar, In : Biomolecules and Therapeutics. 25, 2, p. 112-121 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

In vivo near-infrared imaging and phototherapy of tumors using a cathepsin B-activated fluorescent probe

Chen, X., Lee, D., Yu, S., Kim, G., Lee, S., Cho, Y., Jeong, H., Nam, K. T. & Yoon, J., 2017 Apr 1, In : Biomaterials. 122, p. 130-140 11 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Low-dose bisphenol A increases bile duct proliferation in juvenile rats: A possible evidence for risk of liver cancer in the exposed population?

Jeong, J. S., Nam, K. T., Lee, B., Pamungkas, A. D., Song, D., Kim, M., Yu, W. J., Lee, J., Jee, S., Park, Y. H. & Lim, K. M., 2017 Sep, In : Biomolecules and Therapeutics. 25, 5, p. 545-552 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Modified Mouse Models of Chronic Secondary Lymphedema: Tail and Hind Limb Models

Jun, H., Lee, J. Y., Kim, J. H., Noh, M., Kwon, T. W., Cho, Y. P. & Yoon, Y. S., 2017 Jan 1, In : Annals of Vascular Surgery. 43, p. 288-295 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Novel vaccine potential of Rv3131, a DosR regulon-encoded putative nitroreductase, against hyper-virulent Mycobacterium tuberculosis strain K

Kwon, K. W., Kim, W. S., Kim, H., Han, S. J., Hahn, M. Y., Lee, J. S., Nam, K. T., Cho, S. N. & Shin, S. J., 2017 Mar 8, In : Scientific reports. 7, 44151.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016

Bone marrow-derived mesenchymal stem cells improve diabetic neuropathy by direct modulation of both angiogenesis and myelination in peripheral nerves

Han, J. W., Choi, D., Lee, M. Y., Huh, Y. H. & Yoon, Y. S., 2016 Jan 1, In : Cell transplantation. 25, 2, p. 313-326 14 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis

Lee, D. H., Han, D. H., Nam, K. T., Park, J. S., Kim, S. H., Lee, M., Kim, G., Min, B. S., Cha, B. S., Lee, Y. S., Sung, S. H., Jeong, H., Ji, H. W., Lee, M. J., Lee, J. S., Lee, H. Y., Chun, Y., Kim, J., Komatsu, M., Lee, Y. H. & 1 others, Bae, S. H., 2016 Oct 1, In : Free Radical Biology and Medicine. 99, p. 520-532 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

miR-30-HNF4γ and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomach

Sousa, J. F., Nam, K. T., Petersen, C. P., Lee, H. J., Yang, H. K., Kim, W. H. & Goldenring, J. R., 2016 Jun 1, In : Gut. 65, 6, p. 914-924 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Novel Multifunctional Nanomatrix Reduces Inflammation in Dynamic Conditions in Vitro and Dilates Arteries ex Vivo

Alexander, G. C., Vines, J. B., Hwang, P., Kim, T., Kim, J. A., Brott, B. C., Yoon, Y. S. & Jun, H. W., 2016 Mar 2, In : ACS Applied Materials and Interfaces. 8, 8, p. 5178-5187 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Therapeutic effects of late outgrowth endothelial progenitor cells or mesenchymal stem cells derived from human umbilical cord blood on infarct repair

Kim, S. W., Jin, H. L., Kang, S. M., Kim, S., Yoo, K. J., Jang, Y., Kim, H. O. & Yoon, Y. S., 2016 Jan 15, In : International Journal of Cardiology. 203, p. 498-507 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2015

Diabetic mesenchymal stem cells are ineffective for improving limb ischemia due to their impaired angiogenic capability

Kim, H., Han, J. W., Lee, J. Y., Choi, Y. J., Sohn, Y. D., Song, M. & Yoon, Y. S., 2015 Aug 19, In : Cell transplantation. 24, 8, p. 1571-1584 14 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Dynamic Expansion of Gastric Mucosal Doublecortin-Like Kinase 1-Expressing Cells in Response to Parietal Cell Loss Is Regulated by Gastrin

Choi, E., Petersen, C. P., Lapierre, L. A., Williams, J. A., Weis, V. G., Goldenring, J. R. & Nam, K. T., 2015 Aug 1, In : American Journal of Pathology. 185, 8, p. 2219-2231 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Enhanced therapeutic neovascularization by CD31-expressing cells and embryonic stem cell-derived endothelial cells engineered with chitosan hydrogel containing VEGF-releasing microtubes

Lee, S., Valmikinathan, C. M., Byun, J., Kim, S., Lee, G., Mokarram, N., Pai, S. B., Um, E., Bellamkonda, R. V. & Yoon, Y. S., 2015 Sep 1, In : Biomaterials. 63, p. 158-167 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Generation of pure lymphatic endothelial cells from human pluripotent stem cells and their therapeutic effects on wound repair

Lee, S. J., Park, C., Lee, J. Y., Kim, S., Kwon, P. J., Kim, W., Jeon, Y. H., Lee, E. & Yoon, Y. S., 2015 Jun 12, In : Scientific reports. 5, 11019.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Non-genetic Purification of Ventricular Cardiomyocytes from Differentiating Embryonic Stem Cells through Molecular Beacons Targeting IRX-4

Ban, K., Wile, B., Cho, K. W., Kim, S., Song, M. K., Kim, S. Y., Singer, J., Syed, A., Yu, S. P., Wagner, M., Bao, G. & Yoon, Y. S., 2015 Dec 8, In : Stem Cell Reports. 5, 6, p. 1239-1249 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The mRNA and Protein Levels of Tubulin and β-Actin Are Greatly Reduced in the Proximal Duodenum of Mice Relative to the Rest of the Small Intestines

Yu, S., Hwang, H. E., Yun, N., Goldenring, J. R. & Nam, K. T., 2015 Sep 22, In : Digestive diseases and sciences. 60, 9, p. 2670-2676 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

Cell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrum

Choi, E., Roland, J. T., Barlow, B. J., O'Neal, R., Rich, A. E., Nam, K. T., Shi, C. & Goldenring, J. R., 2014 Nov 1, In : Gut. 63, 11, p. 1711-1720 10 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Cell therapy with embryonic stem cell-derived cardiomyocytes encapsulated in injectable nanomatrix gel enhances cell engraftment and promotes cardiac repair

Ban, K., Park, H. J., Kim, S., Andukuri, A., Cho, K. W., Hwang, J. W., Cha, H. J., Kim, S. Y., Kim, W. S., Jun, H. W. & Yoon, Y. S., 2014 Oct 28, In : ACS Nano. 8, 10, p. 10815-10825 11 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Cultured human bone marrow-derived CD31+ cells are effective for cardiac and vascular repair through enhanced angiogenic, adhesion, and anti-inflammatory effects

Kim, S. W., Houge, M., Brown, M., Davis, M. E. & Yoon, Y. S., 2014 Oct 21, In : Journal of the American College of Cardiology. 64, 16, p. 1681-1694 14 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Evaluation of the effect of expansion and shear stress on a self-assembled endothelium mimicking nanomatrix coating for drug eluting stents in vitro and in vivo

Andukuri, A., Min, I., Hwang, P., Alexander, G., Marshall, L. E., Berry, J. L., Wick, T. M., Joung, Y. K., Yoon, Y. S., Brott, B. C., Han, D. K. & Jun, H. W., 2014 Jan 1, In : Biofabrication. 6, 3, 35019.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion

Crawley, S. W., Shifrin, D. A., Grega-Larson, N. E., McConnell, R. E., Benesh, A. E., Mao, S., Zheng, Y., Zheng, Q. Y., Nam, K. T., Millis, B. A., Kachar, B. & Tyska, M. J., 2014 Apr 10, In : Cell. 157, 2, p. 433-446 14 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells

Petersen, C. P., Weis, V. G., Nam, K. T., Sousa, J. F., Fingleton, B. & Goldenring, J. R., 2014 Jun, In : Gastroenterology. 146, 7, p. 1727-1738.e8

Research output: Contribution to journalArticle

44 Citations (Scopus)