Department of Pharmacy

Research Output 1990 2019

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2019

1,2-Dichloropropane (1,2-DCP)-induced angiogenesis in dermatitis

Jin, M., Hong, Y., Lee, H., Tran, Q., Cho, H., Kim, M., Kwon, S. H., Kang, N. H., Park, J. & Park, J., 2019 Jan 1, In : Toxicological Research. 35, 4, p. 361-369 9 p.

Research output: Contribution to journalArticle

Open Access
Dermatitis
Proto-Oncogene Proteins c-akt
Skin
Sirolimus
Ear

A chemical compound from fruit extract of Juglans mandshurica inhibits melanogenesis through p-ERK-associated MITF degradation

Kim, J. Y., Lee, E. J., Ahn, Y., Park, S. J., Kim, S. H. & Oh, S. H., 2019 Apr, In : Phytomedicine. 57, p. 57-64 8 p.

Research output: Contribution to journalArticle

Microphthalmia-Associated Transcription Factor
Juglans
Fruit
Melanoma
Melanocytes
1 Citation (Scopus)

Alkaloid glycosides and their cytotoxic constituents from Zanthoxylum nitidum

Van, N. T. H., Tuyen, T. T., Quan, P. M., Long, P. Q., Nhiem, N. X., Tai, B. H., Inh, C. T., Hoang, V. D., Van Kiem, P., Van Minh, C., Park, S. J. & Kim, S. H., 2019 Aug, In : Phytochemistry Letters. 32, p. 47-51 5 p.

Research output: Contribution to journalArticle

Zanthoxylum
Glycosides
Alkaloids
glycosides
alkaloids

A new naphthoquinone analogue and antiviral constituents from the root of Rhinacanthus nasutus

Ngoc, T. M., Phuong, N. T. T., Khoi, N. M., Park, S. J., Kwak, H. J., Nhiem, N. X., Trang, B. T. T., Tai, B. H., Song, J. H., Ko, H. J. & Kim, S. H., 2019 Feb 1, In : Natural Product Research. 33, 3, p. 360-366 7 p.

Research output: Contribution to journalArticle

Naphthoquinones
naphthoquinones
Antiviral Agents
Acanthaceae
Vero Cells

A new role for the ginsenoside RG3 in antiaging via mitochondria function in ultraviolet-irradiated human dermal fibroblasts

Lee, H., Hong, Y., Tran, Q., Cho, H., Kim, M., Kim, C., Kwon, S. H., Park, S. J., Park, J. & Park, J., 2019 Jul, In : Journal of Ginseng Research. 43, 3, p. 431-441 11 p.

Research output: Contribution to journalArticle

Ginsenosides
Mitochondria
Fibroblasts
Antioxidants
Cells
1 Citation (Scopus)

An Iodide-Yellow Fluorescent Protein-Gap Junction-Intercellular Communication Assay

Yeo, J. H. & Lee, J., 2019 Feb 1, In : Journal of visualized experiments : JoVE. 144

Research output: Contribution to journalArticle

Connexins
Iodides
Assays
Proteins
Gap Junctions
5 Citations (Scopus)

A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer

Park, J., Cho, Y. H., Shin, W. J., Lee, S. K., Lee, J. H., Kim, T., Cha, P. H., Yang, J. S., Cho, J., Min, D. S., Han, G., Lee, H. Y. & Choi, K. Y., 2019 Dec 1, In : Scientific reports. 9, 1, 648.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Catenins
Wnt Signaling Pathway

A Spatial Analysis of Preventable Hospitalization for Ambulatory Care Sensitive Conditions and Regional Characteristics in South Korea

Kim, J., Kang, H. Y., Lee, K. S., Min, S. & Shin, E., 2019 Jul 1, In : Asia-Pacific Journal of Public Health. 31, 5, p. 422-432 11 p.

Research output: Contribution to journalArticle

Republic of Korea
Spatial Analysis
Ambulatory Care
Hospitalization
Primary Health Care

Assessment of the validity of multiple obesity indices compared with obesity-related co-morbidities

Myung, J., Jung, K. Y., Kim, T. H. & Han, E., 2019 May 1, In : Public Health Nutrition. 22, 7, p. 1241-1249 9 p.

Research output: Contribution to journalArticle

Obesity
Morbidity
Nutrition Surveys
Waist Circumference
Korea
Prehypertension
Adiposity
Hypertension
Area Under Curve
Body Mass Index

A therapeutic strategy for chemotherapy-resistant gastric cancer via destabilization of both β-catenin and ras

Ryu, W. J., Lee, J. E., Cho, Y. H., Lee, G., Seo, M. K., Lee, S. K., Hwang, J. H., Min, D. S., Noh, S. H., Paik, S., Kim, S., Cheong, J. H. & Choi, K. Y., 2019 Apr, In : Cancers. 11, 4, 496.

Research output: Contribution to journalArticle

Open Access
Catenins
Stomach Neoplasms
Drug Therapy
oxaliplatin
Heterografts
2 Citations (Scopus)

Avocado oil extract modulates auditory hair cell function through the regulation of amino acid biosynthesis genes

Nam, Y. H., Rodriguez, I., Jeong, S. Y., Pham, T. N. M., Nuankaew, W., Kim, Y. H., Castañeda, R., Jeong, S. Y., Park, M. S., Lee, K. W., Lee, J. S., Kim, D. H., Park, Y. H., Kim, S. H., Moon, I. S., Choung, S. Y., Hong, B. N., Jeong, K. W. & Kang, T. H., 2019 Jan, In : Nutrients. 11, 1

Research output: Contribution to journalArticle

avocado oil
Auditory Hair Cells
Persea
Sensorineural Hearing Loss
hearing

Body mass index and clinical outcomes in patients after ischaemic stroke in South Korea: A retrospective cohort study

Choi, H., Nam, H. S. & Han, E., 2019 Aug 1, In : BMJ open. 9, 8, e028880.

Research output: Contribution to journalArticle

Open Access
Republic of Korea
Body Mass Index
Cohort Studies
Retrospective Studies
Stroke

Change in sedative burden after dementia onset using difference-in-difference estimations

Ah, Y. M., Han, E., Jun, K., Yu, Y. M. & Lee, J. Y., 2019 Jan 1, In : PloS one. 14, 8, e0220582.

Research output: Contribution to journalArticle

Open Access
sedatives
dementia
Hypnotics and Sedatives
Dementia
drug therapy

Chemical components from the twigs of Caesalpinia latisiliqua and their antiviral activity

Oh, M., Park, S. J., Song, J. H., Ko, H. J. & Kim, S. H., 2019 Jan 1, (Accepted/In press) In : Journal of Natural Medicines.

Research output: Contribution to journalArticle

Caesalpinia
Stilbenes
Flavonoids
Antiviral Agents
Phytochemicals

Chemical constituents from the fruits of Schisandra sphenanthera and their cytotoxicity activity

Kwak, H. J., Park, S. J., Yoo, G., Park, J. H., Oh, Y., Oh, M., Nhiem, N. X., Kim, Y. N., Jeong, E. J. & Kim, S. H., 2019 Sep 1, In : Brazilian Journal of Pharmacognosy. 29, 5, p. 578-581 4 p.

Research output: Contribution to journalArticle

Open Access
Schisandraceae
Schisandra
HCT116 Cells
Lignans
Sleep Initiation and Maintenance Disorders

Chemical constituents of leaves of Persea americana (avocado) and their protective effects against neomycin-induced hair cell damage

Park, S. J., Nam, Y. H., Rodriguez, I., Park, J. H., Kwak, H. J., Oh, Y., Oh, M., Park, M. S., Lee, K. W., Lee, J. S., Kim, D. H., Park, Y. H., Moon, I. S., Choung, S. Y., Jeong, K. W., Hong, B. N., Kang, T. H. & Kim, S. H., 2019 Jan 1, (Accepted/In press) In : Brazilian Journal of Pharmacognosy.

Research output: Contribution to journalArticle

Open Access
Persea
Neomycin
Glycosides
Lignans
Cell Survival
1 Citation (Scopus)

Clobazam as an adjunctive treatment for infantile spasms

Hahn, J., Lee, H., Kang, H. C., Lee, J. S., Kim, H. D., Kim, S. H. & Chang, M. J., 2019 Jun, In : Epilepsy and Behavior. 95, p. 161-165 5 p.

Research output: Contribution to journalArticle

Infantile Spasms
Spasm
Anticonvulsants
Therapeutics
Seizures
11 Citations (Scopus)

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

AstraZeneca-Sanger Drug Combination DREAM Consortium, 2019 Dec 1, In : Nature communications. 10, 1, 2674.

Research output: Contribution to journalArticle

Open Access
Pharmacogenetics
Drug Combinations
drugs
cancer
predictions
1 Citation (Scopus)

Comparison of acute kidney injury and clinical prognosis of vancomycin monotherapy and combination therapy with beta-lactams in the intensive care unit

Kang, S., Park, J., Yu, Y. M., Park, M. S., Han, E. & Chang, M. J., 2019 Jun, In : PloS one. 14, 6, e0217908.

Research output: Contribution to journalArticle

Open Access
beta-lactams
Intensive care units
vancomycin
beta-Lactams
Vancomycin
1 Citation (Scopus)

Comparison of three heterochromatin protein 1 homologs in Drosophila

Lee, D. H., Ryu, H. W., Kim, G. W. & Kwon, S. H., 2019 Feb 7, In : Journal of cell science. 132, 3

Research output: Contribution to journalArticle

Open Access
Drosophila
Eukaryota
Cytoplasm
RNA Polymerase II
heterochromatin-specific nonhistone chromosomal protein HP-1
1 Citation (Scopus)

Convergent synthesis of diptoindonesin G

Singh, D. K. & Kim, I., 2019 Jan 17, In : Tetrahedron Letters. 60, 3, p. 300-301 2 p.

Research output: Contribution to journalArticle

Acylation
Cross Reactions
Biological Products
diptoindonesin G

Cost-effectiveness analysis of the implementation of a National Immunization Program for rotavirus vaccination in a country with a low rotavirus gastroenteritis-related mortality: A South Korean study

Lee, H., Park, S. Y., Clark, A., Debellut, F., Pecenka, C., Kim, D. S., Kim, H. M., Kim, J. H., Cho, H., Kim, A. Y., Lee, M., Jung, S. Y., Seong, B. L. & Kang, H. Y., 2019 Aug 14, In : Vaccine. 37, 35, p. 4987-4995 9 p.

Research output: Contribution to journalArticle

Open Access
Rotavirus Vaccines
Immunization Programs
Rotavirus
gastroenteritis
Gastroenteritis
2 Citations (Scopus)

Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis

Lee, E. J., Kim, J. Y., Ahn, Y., Lee, B. M., Heo, Y., Hwang, S., Lee, S. H., Lee, J., Chung, G. & Oh, S. H., 2019 Jul, In : Journal of Investigative Dermatology. 139, 7, p. 1554-1563.e6

Research output: Contribution to journalArticle

Purinergic P2X7 Receptors
Adenosine
Adenosine Triphosphate
Skin
Skin Pigmentation
1 Citation (Scopus)

Cycloartane-type triterpenoid derivatives and a flavonoid glycoside from the burs of Castanea crenata

Kim, N., Park, S. J., Nhiem, N. X., Song, J. H., Ko, H. J. & Kim, S. H., 2019 Feb, In : Phytochemistry. 158, p. 135-141 7 p.

Research output: Contribution to journalArticle

Castanea crenata
kaempferol
Glycosides
triterpenoids
Flavonoids
1 Citation (Scopus)

Dendrimer-Based Platform for Effective Capture of Tumor Cells after TGFβ1-Induced Epithelial-Mesenchymal Transition

Myung, J. H., Cha, A., Tam, K. A., Poellmann, M., Borgeat, A., Sharifi, R., Molokie, R. E., Votta-Velis, G. & Hong, S., 2019 Jul 2, In : Analytical Chemistry. 91, 13, p. 8374-8382 9 p.

Research output: Contribution to journalArticle

Dendrimers
Transforming Growth Factors
Tumors
Cells
Cell Adhesion Molecules
4 Citations (Scopus)

Design, synthesis, and biological evaluation of novel pyrrolo[1,2-a]pyrazine derivatives

Kim, J., Park, M., Choi, J., Singh, D. K., Kwon, H. J., Kim, S. H. & Kim, I., 2019 Jun 1, In : Bioorganic and Medicinal Chemistry Letters. 29, 11, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

Pyrazines
U937 Cells
Bearings (structural)
Small Molecule Libraries
Derivatives

Development and validation of the Korean version of the medication regimen complexity index

Lee, S., Jang, J. Y., Yang, S., Hahn, J., Min, K. L., Jung, E. H., Oh, K. S., Cho, R. & Chang, M. J., 2019 May, In : PloS one. 14, 5, e0216805.

Research output: Contribution to journalArticle

Open Access
Drug-Related Side Effects and Adverse Reactions
drug therapy
Korea
Reliability analysis
Length of Stay
2 Citations (Scopus)

Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015

Kim, J. H., Eom, H. J., Lim, G. T., Park, S., Lee, J., Nam, S., Kim, Y. H. & Jeong, J. H., 2019 Mar 5, In : British journal of cancer. 120, 5, p. 488-498 11 p.

Research output: Contribution to journalArticle

Open Access
Stomach Neoplasms
Hepatocyte Nuclear Factor 4
Down-Regulation
Surface Plasmon Resonance
Tumor Biomarkers
1 Citation (Scopus)

Discovery of cycloartane-type triterpene saponins from Mussaenda glabra

Thu, V. K., Bach, N. X., Anh, L. T., Trang, D. T., Nhiem, N. X., Tai, B. H., Van Kiem, P., Van Minh, C., Park, S. J., Seo, Y., Namkung, W. & Kim, S. H., 2019 Oct, In : Phytochemistry Letters. 33, p. 39-45 7 p.

Research output: Contribution to journalArticle

Mussaenda
chloride channels
Triterpenes
Chloride Channels
triterpenoid saponins

Effect of Polymer Type on the Dissolution Profile of a Solid Dispersion of Cilostazol

Lee, D., Ha, E. S., Ha, D. H., Sim, W. Y., Choi, J. E., Kim, M. S., Cho, C. W. & Hwang, S. J., 2019 Apr 1, In : Bulletin of the Korean Chemical Society. 40, 4, p. 370-373 4 p.

Research output: Contribution to journalArticle

Polymers
Dissolution
cilostazol

Effect of stabilizers on encapsulation efficiency and release behavior of exenatide-loaded PLGA microsphere prepared by the W/O/W solvent evaporation method

Park, H., Ha, D. H., Ha, E. S., Kim, J. S., Kim, M. S. & Hwang, S. J., 2019 Nov, In : Pharmaceutics. 11, 12, 627.

Research output: Contribution to journalArticle

Open Access
Microspheres
Oils
Water
Adsorption
Poloxamer

Effects of oxytocin on cell proliferation in a corticotroph adenoma cell line

Lim, J. S., Eom, Y. W., Lee, E. S., Kwon, H. J., Kwon, J. Y., Choi, J., Chung, C. H., Jo, Y. S. & Lee, E. J., 2019 Jan 1, In : Endocrinology and Metabolism. 34, 3, p. 302-313 12 p.

Research output: Contribution to journalArticle

Open Access
ACTH-Secreting Pituitary Adenoma
Oxytocin
Cell Proliferation
Cell Line
Proliferating Cell Nuclear Antigen
3 Citations (Scopus)

Electrophilic acetylation and formylation of pyrrolo[1,2-a]pyrazines: Substituent effects on regioselectivity

Singh, D. K. & Kim, I., 2019 Jan 12, In : Arkivoc. 2019, 3, p. 8-21 14 p.

Research output: Contribution to journalArticle

Pyrazines
Acetylation
Regioselectivity

Estrogen receptor-mediated transcriptional activities of spent coffee grounds and spent coffee grounds compost, and their phenolic acid constituents

An, B. H., Jeong, H., Kim, J. H., Park, S., Jeong, J. H., Kim, M. J. & Chang, M., 2019 Aug 7, In : Journal of Agricultural and Food Chemistry. 67, 31, p. 8649-8659 11 p.

Research output: Contribution to journalArticle

Coffee
phenolic acids
Estrogen Receptors
composts
estrogens
2 Citations (Scopus)

Fluorescent 1,4-Naphthoquinones to Visualize Diffuse and Dense-Core Amyloid Plaques in APP/PS1 Transgenic Mouse Brains

Neo Shin, N., Jeon, H., Jung, Y., Baek, S., Lee, S., Yoo, H. C., Bae, G. H., Park, K., Yang, S. H., Han, J. M., Kim, I. & Kim, Y., 2019 Jun 19, In : ACS Chemical Neuroscience. 10, 6, p. 3031-3044 14 p.

Research output: Contribution to journalArticle

Amyloid Plaques
Amyloid
Transgenic Mice
Brain
Imaging techniques

Fluorescent 1,4-Naphthoquinones To Visualize Diffuse and Dense-Core Amyloid Plaques in APP/PS1 Transgenic Mouse Brains

Neo Shin, N., Jeon, H., Jung, Y., Baek, S., Lee, S., Yoo, H. C., Bae, G. H., Park, K., Yang, S-H., Han, J. M., Kim, I. & Kim, Y., 2019 Apr 24, In : ACS Chemical Neuroscience.

Research output: Contribution to journalArticle

Amyloid Plaques
Amyloid
Transgenic Mice
Brain
Imaging techniques

Ginseng berry extract enhances metformin efficacy against obesity and hepatic steatosis in mice fed high-fat diet through increase of metformin uptake in liver

Chae, H. S., You, B. H., Choi, J., Chin, Y. W., Kim, H., Choi, H. S. & Choi, Y. H., 2019 Nov, In : Journal of Functional Foods. 62, 103551.

Research output: Contribution to journalArticle

metformin
Panax
Metformin
fatty liver
High Fat Diet

Glycoprotein 96 polymorphisms are associated with the risk of systemic lupus erythematosus: A case-control study

Lee, J. S., Im, C. H., Lee, S. J., Choi, J. Y., Han, J. M., Kim, S., Kim, D. J., Park, T., Lee, E. Y. & Song, Y. W., 2019 May, In : International Journal of Rheumatic Diseases. 22, 5, p. 905-912 8 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Case-Control Studies
Glycoproteins
Haplotypes
Odds Ratio

HDAC6-selective inhibitor synergistically enhances the anticancer activity of immunomodulatory drugs in multiple myeloma

Won, H. R., Lee, D. H., Yeon, S. K., Ryu, H. W., Kim, G. W. & Kwon, S. H., 2019 Jan 1, In : International journal of oncology. 55, 2, p. 499-512 14 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Pharmaceutical Preparations
Dexamethasone
Histone Deacetylase Inhibitors
Mitogen-Activated Protein Kinase 3
1 Citation (Scopus)

Healthcare use among persons with visual impairment: Difference-in-difference estimations

Kim, T. H., Koo, H. & Han, E., 2019 Apr, In : Disability and Health Journal. 12, 2, p. 302-309 8 p.

Research output: Contribution to journalArticle

Vision Disorders
Health Expenditures
Delivery of Health Care
National Health Programs
Health Insurance

Heterogeneity in costs and prognosis for acute ischemic stroke treatment by comorbidities

Han, E., Kim, T. H., Koo, H., Yoo, J., Heo, J. H. & Nam, H. S., 2019 Jan 1, In : Journal of Neurology.

Research output: Contribution to journalArticle

Comorbidity
Stroke
Costs and Cost Analysis
Therapeutics
Recurrence

Hypoxia improves hair inductivity of dermal papilla cells via nuclear NADPH oxidase 4-mediated reactive oxygen species generation'

Zheng, M., Jang, Y., Choi, N., Kim, D. Y., Han, T. W., Yeo, J. H., Lee, J. & Sung, J. H., 2019 Sep 1, In : British Journal of Dermatology. 181, 3, p. 523-534 12 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Hair
Reactive Oxygen Species
Skin
Hypoxia

Impact of anticholinergic burden on emergency department visits among older adults in Korea: A national population cohort study

Hwang, S., Jun, K., Ah, Y. M., Han, E., Chung, J. E. & Lee, J. Y., 2019 Nov 1, In : Archives of Gerontology and Geriatrics. 85, 103912.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Korea
Hospital Emergency Service
Cohort Studies
Population
8 Citations (Scopus)

Impact of H3.3 K27M mutation on prognosis and survival of grade IV spinal cord Glioma on the basis of new 2016 world health organization classification of the central nervous system

Yi, S., Choi, S., Ah Shin, D., Su Kim, D., Choi, J., Ha, Y., Kim, K. N., Suh, C. O., Chang, J. H., Kim, S. H. & Yoon, D. H., 2019 Jan 1, In : Neurosurgery. 84, 5, p. 1072-1081 10 p.

Research output: Contribution to journalArticle

Glioma
Spinal Cord
Central Nervous System
Mutation
Survival
2 Citations (Scopus)

Impact of obesity on employment and wages among young adults: Observational study with panel data

Lee, H., Ahn, R., Kim, T. H. & Han, E., 2019 Jan 1, In : International journal of environmental research and public health. 16, 1, 139.

Research output: Contribution to journalArticle

Salaries and Fringe Benefits
Observational Studies
Young Adult
Obesity
Logistic Models

Inhibition of gap junctional intercellular communication by an anti-migraine agent, flunarizine

Yeo, J. H., Choi, E. J. & Lee, J., 2019 Jan 1, In : PloS one. 14, 9, e0222326.

Research output: Contribution to journalArticle

Open Access
Flunarizine
migraine
cell communication
gap junctions
Migraine Disorders
1 Citation (Scopus)
systematic review
green tea
Tea
meta-analysis
body mass index

Intramolecular Electrophilic Cyclization Approach to 6-Substituted Naphtho[2,1- b]benzofurans: Novel Dual-State Emissive Fluorophores with Blue Emission

Singh, D. K., Jang, K., Kim, J., Lee, J. & Kim, I., 2019 May 13, In : ACS Combinatorial Science. 21, 5, p. 408-416 9 p.

Research output: Contribution to journalArticle

Benzofurans
Fluorophores
Cyclization
Imaging systems
Screening

Isolation of amylase regulators from the leaves of Ixeridium dentatum

Park, S. J., Nhiem, N. X., Park, J. H., Bhattarai, K. R., Chae, H. J., Kim, H. R. & Kim, S. H., 2019 Jan 1, In : Natural Product Research.

Research output: Contribution to journalArticle

Amylases
amylases
secretion
Luteolin
leaves