Interdisciplinary Program of Integrated OMICS for Biomedical Sciences

Research Output

Article

2-(Trimethylammonium)ethyl (R)-3-methoxy-3-oxo-2-stearamidopropyl phosphate promotes megakaryocytic differentiation of myeloid leukaemia cells and primary human CD34+ haematopoietic stem cells

Limb, J. K., Song, D., Jeon, M., Han, S. Y., Han, G., Jhon, G. J., Bae, Y. S. & Kim, J., 2015 Apr 1, In : Journal of Tissue Engineering and Regenerative Medicine. 9, 4, p. 435-446 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

200+ Protein Concentrations in Healthy Human Blood Plasma: Targeted Quantitative SRM SIS Screening of Chromosomes 18, 13, Y, and the Mitochondrial Chromosome Encoded Proteome

Kopylov, A. T., Ponomarenko, E. A., Ilgisonis, E. V., Pyatnitskiy, M. A., Lisitsa, A. V., Poverennaya, E. V., Kiseleva, O. I., Farafonova, T. E., Tikhonova, O. V., Zavialova, M. G., Novikova, S. E., Moshkovskii, S. A., Radko, S. P., Morukov, B. V., Grigoriev, A. I., Paik, Y. K., Salekdeh, G. H., Urbani, A., Zgoda, V. G. & Archakov, A. I., 2019 Jan 4, In : Journal of Proteome Research. 18, 1, p. 120-129 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

2'-5' oligoadenylate synthetase-like 1 (OASL1) deficiency suppresses central nervous system damage in a murine MOG-induced multiple sclerosis model

Choi, B. Y., Sim, C. K., Cho, Y. S., Sohn, M., Kim, Y. J., Lee, M. S. & Suh, S. W., 2016 Aug 15, In : Neuroscience Letters. 628, p. 78-84 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

2′–5′ Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons

Sim, C. K., Cho, Y. S., Kim, B. S., Baek, I. J., Kim, Y. J. & Lee, M. S., 2016 Jun 1, In : Cancer Immunology, Immunotherapy. 65, 6, p. 663-675 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
22 Citations (Scopus)

A248, a novel synthetic HDAC inhibitor, induces apoptosis through the inhibition of specificity protein 1 and its downstream proteins in human prostate cancer cells

Choi, E. S., Han, G., Park, S. K., Lee, K., Kim, H. J., Cho, S. D. & Kim, H. M., 2013 Jul, In : Molecular Medicine Reports. 8, 1, p. 195-200 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abundance-ratio-based semiquantitative analysis of site-specific N-linked glycopeptides present in the plasma of hepatocellular carcinoma patients

Lee, H. J., Cha, H. J., Lim, J. S., Lee, S. H., Song, S. Y., Kim, H., Hancock, W. S., Yoo, J. S. & Paik, Y. K., 2014 May 2, In : Journal of Proteome Research. 13, 5, p. 2328-2338 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

A conserved neuronal DAF-16/FoxO plays an important role in conveying pheromone signals to elicit repulsion behavior in Caenorhabditis elegans

Park, D., Hahm, J. H., Park, S., Ha, G., Chang, G. E., Jeong, H., Kim, H., Kim, S., Cheong, E. & Paik, Y. K., 2017 Dec 1, In : Scientific reports. 7, 1, 7260.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A convenient synthetic method for amide oxidation

Han, G., McIntosh, M. C. & Weinreb, S. M., 1994 Aug 8, In : Tetrahedron Letters. 35, 32, p. 5813-5816 4 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: Evidence for catalytic difference between ACAT1 and ACAT2

An, S., Cho, K. H., Lee, W. S., Lee, J. O., Paik, Y. K. & Jeong, T. S., 2006 May 15, In : FEBS Letters. 580, 11, p. 2741-2749 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Activation of c-Jun N-terminal kinase is required for neurite outgrowth of dopaminergic neuronal cells

Eom, D. S., Choi, W. S., Ji, S., Cho, J. W. & Oh, Y. J., 2005 May 31, In : NeuroReport. 16, 8, p. 823-828 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Activation of MEK-ERK by heregulin-β1 promotes the development of cardiomyocytes derived from ES cells

Kim, H. S., Cho, J. W., Hidaka, K. & Morisaki, T., 2007 Sep 28, In : Biochemical and Biophysical Research Communications. 361, 3, p. 732-738 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Activation of phospholipase D1 by direct interaction with ADP- ribosylation factor 1 and Ra1A

Kim, J. H., Lee, S. D., Han, J. M., Lee, T. G., Kim, Y., Park, J. B., Lambeth, J. D., Suh, P. G. & Ryu, S. H., 1998 Jul 3, In : FEBS Letters. 430, 3, p. 231-235 5 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Activation of phospholipase Dl by direct interaction with ADP-ribosylation factorl and RalA

Kim, J. H., Lee, S. D., Han, J. M., Lee, T. G., Kirn, Y., Park, J. B., Suh, P. G. & Ryu, S. H., 1998, In : FASEB Journal. 12, 8, p. A1383

Research output: Contribution to journalArticle

Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation

Han, S. J., Lee, Y. C., Gim, B. S., Ryu, G. H., Park, S. J., Lane, W. S. & Kim, Y. J., 1999 Feb, In : Molecular and cellular biology. 19, 2, p. 979-988 10 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

A disease- and phosphorylation-related nonmechanical function for keratin 8

Ku, N. O. & Omary, M. B., 2006 Jul 3, In : Journal of Cell Biology. 174, 1, p. 115-125 11 p.

Research output: Contribution to journalArticle

123 Citations (Scopus)

A facile synthesis of 2-acyl and 2-alkylaminobenzimidazoles for 5-lipoxygenase inhibitors

Lee, A. H., An, M. H., Choi, E. H., Choo, H. Y. P. & Han, G., 2006 Dec 31, In : Heterocycles. 70, p. 571-580 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

A facile synthesis of 2-aminothiazolo[5,4-b]pyridines and2-aminobanzoxazoles via cyclization of thioureas

Yoon, J. H., Song, H., Kim, S. W., Han, G. & Choo, H. Y. P., 2005 Nov 1, In : Heterocycles. 65, 11, p. 2729-2740 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A fluorescent natural product for ultra sensitive detection of proteins in one-dimensional and two-dimensional gel electrophoresis

Mackintosh, J. A., Choi, H. Y., Bae, S. H., Veal, D. A., Bell, P. J., Ferrari, B. C., Van Dyk, D. D., Verrills, N. M., Paik, Y. K. & Karuso, P., 2003 Dec, In : Proteomics. 3, 12, p. 2273-2288 16 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

A functional annotation of subproteomes in human plasma

Ping, P., Vondriska, T. M., Creighton, C. J., Gandhi, T. K. B., Yang, Z., Menon, R., Kwon, M. S., Cho, S. Y., Drwal, G., Kellmann, M., Peri, S., Suresh, S., Gronborg, M., Molina, H., Chaerkady, R., Rekha, B., Shet, A. S., Gerszten, R. E., Wu, H., Raftery, M. & 8 others, Wasinger, V., Schulz-Knappe, P., Hanash, S. M., Paik, Y. K., Hancock, W. S., States, D. J., Omenn, G. S. & Pandey, A., 2005 Aug, In : Proteomics. 5, 13, p. 3506-3519 14 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Age-dependent changes of gene expression in the Drosophila head

Kim, S. N., Rhee, J. H., Song, Y. H., Park, D. Y., Hwang, M., Lee, S. L., Kim, J. E., Gim, B. S., Yoon, J. H., Kim, Y. J. & Kim-Ha, J., 2005 Jul, In : Neurobiology of Aging. 26, 7, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Aggregates of oligo(dG) bind and inhibit topoisomerase II activity and induce formation of large networks

Chung, I. K. & Muller, M. T., 1991, In : Journal of Biological Chemistry. 266, 15, p. 9508-9514 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A human antibody that binds to the sixth Ig-like domain of VCAM-1 blocks lung cancer cell migration in vitro

Kim, M. R., Jang, J. H., Park, C. S., Kim, T. K., Kim, Y. J., Chung, J., Shim, H., Nam, I. H., Han, J. M. & Lee, S., 2017 Mar 6, In : International journal of molecular sciences. 18, 3, 566.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A HUPO test sample study reveals common problems in mass spectrometry-based proteomics

Bell, A. W., Deutsch, E. W., Au, C. E., Kearney, R. E., Beavis, R., Sechi, S., Nilsson, T., Bergeron, J. J. M., Beardslee, T. A., Chappell, T., Meredith, G., Sheffield, P., Gray, P., Hajivandi, M., Pope, M., Predki, P., Kullolli, M., Hincapie, M., Hancock, W. S., Jia, W. & 82 others, Song, L., Li, L., Wei, J., Yang, B., Wang, J., Ying, W., Zhang, Y., Cai, Y., Qian, X., He, F., Meyer, H. E., Stephan, C., Eisenacher, M., Marcus, K., Langenfeld, E., May, C., Carr, S. A., Ahmad, R., Zhu, W., Smith, J. W., Hanash, S. M., Struthers, J. J., Wang, H., Zhang, Q., An, Y., Goldman, R., Carlsohn, E., van der Post, S., Hung, K. E., Sarracino, D. A., Parker, K., Krastins, B., Kucherlapati, R., Bourassa, S., Poirier, G. G., Kapp, E., Patsiouras, H., Moritz, R., Simpson, R., Houle, B., LaBoissiere, S., Metalnikov, P., Nguyen, V., Pawson, T., Wong, C. C. L., Cociorva, D., Yates, J. R., Ellison, M. J., Lopez-Campistrous, A., Semchuk, P., Wang, Y., Ping, P., Elia, G., Dunn, M. J., Wynne, K., Walker, A. K., Strahler, J. R., Andrews, P. C., Hood, B. L., Bigbee, W. L., Conrads, T. P., Smith, D., Borchers, C. H., Lajoie, G. A., Bendall, S. C., Speicher, K. D., Speicher, D. W., Fujimoto, M., Nakamura, K., Paik, Y. K., Cho, S. Y., Kwon, M. S., Lee, H. J., Jeong, S. K., Chung, A. S., Miller, C. A., Grimm, R., Williams, K., Dorschel, C., Falkner, J. A., Martens, L. & Vizcaíno, J. A., 2009, In : Nature Methods. 6, 6, p. 423-430 8 p.

Research output: Contribution to journalArticle

247 Citations (Scopus)

AIMP1/p43 downregulates TGF-β signaling via stabilization of smurf2

Lee, Y. S., Han, J. M., Son, S. H., Choi, J. W., Jeon, E. J., Bae, S. C., Park, Y. I. & Kim, S., 2008 Jul 4, In : Biochemical and Biophysical Research Communications. 371, 3, p. 395-400 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

AIMP1 negatively regulates adipogenesis by inhibiting PPARγ

Kim, J. H., Lee, J. H., Park, M. C., Yoon, I., Kim, K., Lee, M., Choi, H. S., Han, J. M. & Kim, S., 2014, In : Journal of cell science. 127, 20, p. 4483-4493 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53

Jung, M. H., Park, B. J., Sang, G. P., Young, S. O., So, J. C., Sang, W. L., Hwang, S. K., Chang, S. H., Cho, M. H. & Kim, S., 2008 Aug 12, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 32, p. 11206-11211 6 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

AIMP2 controls intestinal stem cell compartments and tumorigenesis by modulating Wnt/β-catenin signaling

Yum, M. K., Kang, J. S., Lee, A. E., Jo, Y. W., Seo, J. Y., Kim, H. A., Kim, Y. Y., Seong, J., Lee, E. B., Kim, J. H., Han, J. M., Kim, S. & Kong, Y. Y., 2016 Aug 1, In : Cancer Research. 76, 15, p. 4559-4568 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

AIMP2 promotes TNFα-dependent apoptosis via ubiquitin-mediated degradation of TRAF2

Choi, J. W., Kim, D. G., Park, M. C., Um, J. Y., Han, J. M., Park, S. G., Choi, E. C. & Kim, S., 2009 Aug 1, In : Journal of cell science. 122, 15, p. 2710-2715 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation

Jeong, S. A., Kim, K., Lee, J. H., Cha, J. S., Khadka, P., Cho, H. S. & Chung, I. K., 2015, In : Journal of cell science. 128, 12, p. 2287-2301 15 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Alteration in cellular acetylcholine influences dauer formation in Caenorhabditis elegans

Lee, J., Kim, K. Y. & Paik, Y. K., 2014 Feb, In : BMB reports. 47, 2, p. 80-85 6 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Alteration of the glutamate and GABA transporters in the hippocampus of the Niemann-Pick disease, type C mouse using proteomic analysis

Byun, K., Kim, J., Cho, S. Y., Hutchinson, B., Yang, S. R., Kang, K. S., Cho, M., Hwang, K., Michikawa, M., Jeon, Y. W., Paik, Y. K. & Lee, B., 2006 Feb, In : Proteomics. 6, 4, p. 1230-1236 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Alterations of protein expression in macrophages in response to Candida albicans infection

Shin, Y. K., Kim, K. Y. & Paik, Y. K., 2005, In : Molecules and cells. 20, 2, p. 271-279 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Altered expression of Lewis antigen on tissue and erythrocytes in gastric cancer patients

Kim, M. J., Kim, H. S., Song, K. S., Noh, S. H., Kim, H., Paik, Y. K. & Kim, H. O., 2002 Aug, In : Yonsei medical journal. 43, 4, p. 427-434 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

A method of microinjection: delivering monoclonal antibody 1223 into sea urchin embryos.

Cho, J. W., 1999 Aug 31, In : Molecules and cells. 9, 4, p. 455-458 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: Its pathological implications in lupus-like autoimmune diseases

Jung, M. H., Sang, G. P., Liu, B., Park, B. J., Jin, Y. K., Cheng, H. J., Yeong, W. S., Li, Z. & Kim, S., 2007 Jun, In : American Journal of Pathology. 170, 6, p. 2042-2054 13 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

A molecular basis for reciprocal regulation between pheromones and hormones in response to dietary cues in C. Elegans

Park, S., Park, J. Y. & Paik, Y. K., 2020 Apr 1, In : International journal of molecular sciences. 21, 7, p. 1-12 12 p., 2366.

Research output: Contribution to journalArticle

Open Access

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

Kim, Y. J., Björklund, S., Li, Y., Sayre, M. H. & Kornberg, R. D., 1994 May 20, In : Cell. 77, 4, p. 599-608 10 p.

Research output: Contribution to journalArticle

838 Citations (Scopus)

A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast

Cairns, B. R., Kim, Y. J., Sayre, M. H., Laurent, B. C. & Kornberg, R. D., 1994 Mar 1, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 5, p. 1950-1954 5 p.

Research output: Contribution to journalArticle

331 Citations (Scopus)

A mutation in keratin 18 that causes caspase-digestion resistance protects homozygous transgenic mice from hepatic apoptosis and injury

Yoon, H. N., Yoon, S. Y., Hong, J. H. & Ku, N. O., 2017 Aug 1, In : Journal of cell science. 130, 15, p. 2541-2550 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

An activator binding module of yeast RNA polymerase II holoenzyme

Lee, Y. C., Park, J. M., Min, S., Han, S. J. & Kim, Y. J., 1999 Apr, In : Molecular and cellular biology. 19, 4, p. 2967-2976 10 p.

Research output: Contribution to journalArticle

128 Citations (Scopus)

Analysis of neuron-like differentiation of human bone marrow mesenchymal stem cells

Choi, C. B., Cho, Y. K., Bhanu Prakash, K. V., Jee, B. K., Han, C. W., Paik, Y. K., Kim, H. Y., Lee, K. H., Chung, N. & Rha, H. K., 2006 Nov 10, In : Biochemical and Biophysical Research Communications. 350, 1, p. 138-146 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Analysis of nuclear high mobility group box 1 (HMGB1)-binding proteins in colon cancer cells: Clustering with proteins involved in secretion and extranuclear function

Lee, H., Shin, N., Song, M., Kang, U. B., Yeom, J., Lee, C., Ahn, Y. H., Yoo, J. S., Paik, Y. K. & Kim, H., 2010 Sep 3, In : Journal of Proteome Research. 9, 9, p. 4661-4670 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

An Arabidopsis splicing RNP variant STEP1 regulates telomere length homeostasis by restricting access of nuclease and telomerase

Yoo, H. H., Kwon, C. & Chung, I. K., 2010 Sep, In : Molecules and cells. 30, 3, p. 279-283 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

A new enantioselective approach to total synthesis of the Securinega alkaloids: Application to (-)-norsecurinine and phyllanthine

Gyoonhee, H., LaPorte, M. G., Folmer, J. J., Werner, K. M. & Weinreb, S. M., 2000 Jan 3, In : Angewandte Chemie - International Edition. 39, 1, p. 237-240 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

A New Horizon of Proteomics in Korea

Paik, Y. K., 2003 Dec, In : Proteomics. 3, 12, p. 2271-2272 2 p.

Research output: Contribution to journalArticle

A new synthetic route to 6,7-dichloro-5,8-quinoxaline-dione and synthesis of its derivatives

Han, G., Shin, K. J., Kim, D. C., Yoo, K. H., Kim, D. J. & Park, S. W., 1996, In : Heterocycles. 43, 11, p. 2496-2502 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A new versatile peptide-based size exclusion chromatography platform for global profiling and quantitation of candidate biomarkers in hepatocellular carcinoma specimens

Lee, H. J., Na, K., Kwon, M. S., Park, T., Kim, K. S., Kim, H. & Paik, Y. K., 2011 May, In : Proteomics. 11, 10, p. 1976-1984 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

An integrated proteome database for two-dimensional electrophoresis data analysis and laboratory information management system

Cho, S. Y., Park, K. S., Shim, J. E., Kwon, M. S., Joo, K. H., Lee, W. S., Chang, J., Kim, H., Chung, H. C., Kim, H. O. & Paik, Y. K., 2002 Sep 1, In : Proteomics. 2, 9, p. 1104-1113 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

An international showcase of the rapid expansion of epigenetics

Choi, J. K. & Kim, Y. J., 2009 Dec, In : Epigenomics. 1, 2, p. 235-237 3 p.

Research output: Contribution to journalArticle