Interdisciplinary Program of Integrated OMICS for Biomedical Sciences

Research Output

2011

A novel zinc-carboxypeptidase SURO-1 regulates cuticle formation and body morphogenesis in Caenorhabditis elegans

Kim, T. H., Kim, Y. J., Cho, J. W. & Shim, J., 2011 Jan 3, In : FEBS Letters. 585, 1, p. 121-127 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A potential biochemical mechanism underlying the influence of sterol deprivation stress on Caenorhabditis elegans longevity

Cheong, M., Na, K., Kim, H., Jeong, S. K., Joo, H. J., Chitwood, D. J. & Paik, Y. K., 2011 Mar 4, In : Journal of Biological Chemistry. 286, 9, p. 7248-7256 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

A potential role for fatty acid biosynthesis genes during molting and cuticle formation in Caenorhabditis elegans

Li, Y. & Paik, Y. K., 2011 Apr, In : BMB reports. 44, 4, p. 285-290 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Cancer-associated splicing variant of tumor suppressor AIMP2/p38: Pathological implication in tumorigenesis

Choi, J. W., Kim, D. G., Lee, A. E., Kim, H. R., Lee, J. Y., Kwon, N. H., Shin, Y. K., Hwang, S. K., Chang, S. H., Cho, M. H., Choi, Y. L., Kim, J., Oh, S. H., Kim, B., Kim, S. Y., Jeon, H. S., Park, J. Y., Kang, H. P., Park, B. J., Han, J. M. & 1 others, Kim, S., 2011 Mar, In : PLoS Genetics. 7, 3, e1001351.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Contribution of sams-1 and pmt-1 to lipid homoeostasis in adult Caenorhabditis elegans

Li, Y., Na, K., Lee, H. J., Lee, E. Y. & Paik, Y. K., 2011 May, In : Journal of Biochemistry. 149, 5, p. 529-538 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3

Kwon, N. H., Kang, T., Lee, J. Y., Kim, H. H., Kim, H. R., Hong, J., Oh, Y. S., Han, J. M., Ku, M. J., Lee, S. Y. & Kim, S., 2011 Dec 6, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 49, p. 19635-19640 6 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Editorial: Proteomics, human proteome project, and chromosomes

Hancock, W., Omenn, G., Legrain, P. & Paik, Y. K., 2011 Jan 7, In : Journal of Proteome Research. 10, 1, p. 210 1 p.

Research output: Contribution to journalEditorial

37 Citations (Scopus)

Enhanced peptide quantification using spectral count clustering and cluster abundance

Lee, S., Kwon, M. S., Lee, H. J., Paik, Y. K., Tang, H., Lee, J. K. & Park, T., 2011 Oct 28, In : BMC bioinformatics. 12, 423.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Enhancement of Toll-like receptor 2-mediated immune responses by AIMP1, a novel cytokine, in mouse dendritic cells

Kim, E., Hong, H. J., Cho, D., Han, J. M., Kim, S. & Kim, T. S., 2011 Sep, In : Immunology. 134, 1, p. 73-81 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Entamoeba lysyl-tRNA synthetase contains a cytokine-like domain with chemokine activity towards human endothelial cells

de Moura, M. C., Miro, F., Han, J. M., Kim, S., Celada, A. & Ribas de Pouplana, L., 2011 Nov, In : PLoS Neglected Tropical Diseases. 5, 11, e1398.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Evaluation of the pharmacokinetics and metabolism of a novel histone deacetylase inhibitor, KBH-A40, in rats

Oh, S. J., Lee, K., Ryu, J., Yu, H. E., Han, G., Park, S. K., Kang, J. S., Kim, H. M. & Kim, Y. C., 2011 Feb, In : Xenobiotica. 41, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

GPA-9 is a novel regulator of innate immunity against Escherichia coli foods in adult Caenorhabditis elegans

Hahm, J. H., Kim, S. & Paik, Y. K., 2011 Apr, In : Aging Cell. 10, 2, p. 208-219 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Identification of a novel small molecule targeting UQCRB of mitochondrial complex III and its anti-angiogenic activity

Jung, H. J., Kim, K. H., Kim, N. D., Han, G. & Kwon, H. J., 2011 Feb 1, In : Bioorganic and Medicinal Chemistry Letters. 21, 3, p. 1052-1056 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Identification of DNA methylation changes associated with human gastric cancer

Park, J. H., Park, J., Choi, J. K., Lyu, J., Bae, M. G., Lee, Y. G., Bae, J. B., Park, D. Y., Yang, H. K., Kim, T. Y. & Kim, Y. J., 2011, In : BMC Medical Genomics. 4, 82.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Importin beta plays an essential role in the regulation of the LysRS-Ap4A pathway in immunologically activated mast cells

Carmi-Levy, I., Motzik, A., Ofir-Birin, Y., Yagil, Z., Yang, C. M., Kemeny, D. M., Han, J. M., Kim, S., Kay, G., Nechushtan, H., Suzuki, R., Rivera, J. & Razin, E., 2011 May, In : Molecular and cellular biology. 31, 10, p. 2111-2121 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Methods for Evaluating the Caenorhabditis elegans Dauer State: Standard Dauer-Formation Assay Using Synthetic Daumones and Proteomic Analysis of O-GlcNAc Modifications

Lee, J., Kim, K. Y., Joo, H. J., Kim, H., Jeong, P. Y. & Paik, Y. K., 2011, Methods in Cell Biology. Academic Press Inc., p. 445-460 16 p. (Methods in Cell Biology; vol. 106).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling

Cha, B., Kim, W., Kim, Y. K., Hwang, B. N., Park, S. Y., Yoon, J. W., Park, W. S., Cho, J. W., Bedford, M. T. & Jho, E. H., 2011 May 19, In : Oncogene. 30, 20, p. 2379-2389 11 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Microarray expression profiling in 6-hydroxydopamine-induced dopaminergic neuronal cell death

Park, B., Oh, C. K., Choi, W. S., Chung, I. K., Youdim, M. B. H. & Oh, Y. J., 2011 Nov, In : Journal of Neural Transmission. 118, 11, p. 1585-1598 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Microfluidic assay to study transendothelial migration of human leukocyte

Han, S., Yan, J. J., Shin, Y., Kamm, R. D., Kim, Y. J. & Chung, S., 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. p. 822-824 3 p. (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism

Xu, M., Joo, H. J. & Paik, Y. K., 2011 Aug 12, In : Journal of Biological Chemistry. 286, 32, p. 28111-28118 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

NSC126188, a piperazine alkyl derivative, induces apoptosis via upregulation of RhoB in HeLa cells

Kim, B. K., Kim, D. M., Chung, K. S., Park, S. K., Choi, S. J., Song, A., Lee, K., Lee, C. W., Song, K. B., Han, G., Simon, J., Kim, H. M. & Won, M., 2011 Oct 1, In : Investigational New Drugs. 29, 5, p. 853-860 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

O-GlcNAcylation of tubulin inhibits its polymerization

Ji, S., Kang, J. G., Park, S. Y., Lee, J., Oh, Y. J. & Cho, J. W., 2011 Mar, In : Amino Acids. 40, 3, p. 809-818 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Personalized medicine in the age of pharmacoproteomics: A close up on India and need for social science engagement for responsible innovation in post-proteomic biology

Reddy, P. J., Jain, R., Paik, Y. K., Downey, R., Ptolemy, A. S., Ozdemir, V. & Srivastava, S., 2011 Sep, In : Current Pharmacogenomics and Personalized Medicine. 9, 3, p. 159-167 9 p.

Research output: Contribution to journalEditorial

21 Citations (Scopus)

Protein O-GlcNAcylation regulates Drosophila growth through the insulin signaling pathway

Park, S., Park, S. H., Baek, J. Y., Jy, Y. J., Kim, K. S., Roth, J., Cho, J. W. & Choe, K. M., 2011 Oct, In : Cellular and Molecular Life Sciences. 68, 20, p. 3377-3384 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Proteomic analysis of pancreatic juice for the identification of biomarkers of pancreatic cancer

Park, J. Y., Kim, S. A., Chung, J. W., Bang, S., Park, S. W., Paik, Y. K. & Song, S. Y., 2011 Aug, In : Journal of cancer research and clinical oncology. 137, 8, p. 1229-1238 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Relationship between group-specific component protein and the development of asthma

Lee, S. H., Kim, K. H., Kim, J. M., Yoon, S. H., Kim, T. H., Park, S. W., Park, J. S., Uh, S. T., Lee, H. S., Kim, Y. H., Kang, J. H., Chung, I. Y., Paik, Y. K., Rhim, T. & Park, C. S., 2011 Sep 1, In : American Journal of Respiratory and Critical Care Medicine. 184, 5, p. 528-536 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection

Yoo, H. H. & Chung, I. K., 2011 Aug, In : Aging Cell. 10, 4, p. 557-571 15 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Restoration of senescent human diploid fibroblasts by modulation of the extracellular matrix

Choi, H. R., Cho, K. A., Kang, H. T., Lee, J. B., Kaeberlein, M., Suh, Y., Chung, I. K. & Park, S. C., 2011 Feb, In : Aging Cell. 10, 1, p. 148-157 10 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

STR-33, a novel G protein-coupled receptor that regulates locomotion and egg laying in Caenorhabditis elegans

Lee, J. E., Jeong, P. Y., Joo, H. J., Kim, H., Lee, T., Koo, H. S. & Paik, Y. K., 2011 Nov 18, In : Journal of Biological Chemistry. 286, 46, p. 39860-39870 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors

Choi, E., Lee, C., Park, J. E., Seo, J. J., Cho, M., Kang, J. S., Kim, H. M., Park, S. K., Lee, K. & Han, G., 2011 Feb 15, In : Bioorganic and Medicinal Chemistry Letters. 21, 4, p. 1218-1221 4 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: Part i

Yang, J. S., Song, D., Lee, B., Ko, W. J., Park, S. K., Won, M., Lee, K., Kim, H. M. & Han, G., 2011 Jul, In : European Journal of Medicinal Chemistry. 46, 7, p. 2861-2866 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Synthesis and evaluation of tricyclic derivatives containing a non-aromatic amide as poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors

Park, C. H., Chun, K., Choi, J. H., Ji, W. K., Kim, H. Y., Kim, S. H., Han, G. & Kim, M. H., 2011 May 20, In : Bulletin of the Korean Chemical Society. 32, 5, p. 1650-1656 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Targeted mass spectrometric approach for biomarker discovery and validation with nonglycosylated tryptic peptides from N-linked glycoproteins in human plasma

Lee, J. Y., Kim, J. Y., Park, G. W., Cheon, M. H., Kwon, K. H., Ahn, Y. H., Moon, M. H., Lee, H. J., Paik, Y. K. & Yoo, J. S., 2011 Dec, In : Molecular and Cellular Proteomics. 10, 12

Research output: Contribution to journalArticle

32 Citations (Scopus)

TGF-β-stimulated aberrant expression of class III β-tubulin via the ERK signaling pathway in cultured retinal pigment epithelial cells

Chung, E. J., Chun, J. N., Jung, S. A., Cho, J. W. & Lee, J. H., 2011 Nov 18, In : Biochemical and Biophysical Research Communications. 415, 2, p. 367-372 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The human proteome project: Current state and future direction

Legrain, P., Aebersold, R., Archakov, A., Bairoch, A., Bala, K., Beretta, L., Bergeron, J., Borchers, C. H., Corthals, G. L., Costello, C. E., Deutsch, E. W., Domon, B., Hancock, W., He, F., Hochstrasser, D., Marko-Varga, G., Salekdeh, G. H., Sechi, S., Snyder, M., Srivastava, S. & 5 others, Uhlén, M., Wu, C. H., Yamamoto, T., Paik, Y. K. & Omenn, G. S., 2011 Jul, In : Molecular and Cellular Proteomics. 10, 7

Research output: Contribution to journalArticle

260 Citations (Scopus)

Upregulation of RhoB via c-Jun N-terminal kinase signaling induces apoptosis of the human gastric carcinoma NUGC-3 cells treated with NSC12618

Kim, B. K., Kim, H. M., Chung, K. S., Kim, D. M., Park, S. K., Song, A., Won, K. J., Lee, K., Oh, Y. K., Lee, K., Song, K. B., Simon, J. A., Han, G. & Won, M., 2011, In : Carcinogenesis. 32, 3, p. 254-261 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2010

Analysis of nuclear high mobility group box 1 (HMGB1)-binding proteins in colon cancer cells: Clustering with proteins involved in secretion and extranuclear function

Lee, H., Shin, N., Song, M., Kang, U. B., Yeom, J., Lee, C., Ahn, Y. H., Yoo, J. S., Paik, Y. K. & Kim, H., 2010 Sep 3, In : Journal of Proteome Research. 9, 9, p. 4661-4670 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

An Arabidopsis splicing RNP variant STEP1 regulates telomere length homeostasis by restricting access of nuclease and telomerase

Yoo, H. H., Kwon, C. & Chung, I. K., 2010 Sep, In : Molecules and cells. 30, 3, p. 279-283 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Antitumor activity and pharmacokinetic properties of ARS-interacting multi-functional protein 1 (AIMP1/p43)

Han, J. M., Myung, H. & Kim, S., 2010 Jan 28, In : Cancer Letters. 287, 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Blood-brain barrier defects associated with Rbp9 mutation

Kim, J., Kim, Y. J. & Kim-Ha, J., 2010 Jan, In : Molecules and cells. 29, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Caenorhabditis elegans proteomics comes of age

Shim, Y. H. & Paik, Y. K., 2010 Feb, In : Proteomics. 10, 4, p. 846-857 12 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Caveolae-mediated entry of Salmonella typhimurium into senescent nonphagocytotic host cells

Lim, J. S., Choy, H. E., Park, S. C., Han, J. M., Jang, I. S. & Cho, K. A., 2010 Apr, In : Aging Cell. 9, 2, p. 243-251 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Characterization of in vivo keratin 19 phosphorylation on tyrosine-391

Zhou, Q., Snider, N. T., Liao, J., Li, D. H., Hong, A., Ku, N. O., Cartwright, C. A. & Bishr Omary, M., 2010, In : PloS one. 5, 10, e13538.

Research output: Contribution to journalArticle

10 Citations (Scopus)

CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity

Lee, J. H., Khadka, P., Baek, S. H. & Chung, I. K., 2010 Dec 31, In : Journal of Biological Chemistry. 285, 53, p. 42033-42045 13 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Contribution of the peroxisomal acox gene to the dynamic balance of daumone production in Caenorhabditis elegans

Joo, H. J., Kim, K. Y., Yim, Y. H., Jin, Y. X., Kim, H., Kim, M. Y. & Paik, Y. K., 2010 Sep 17, In : Journal of Biological Chemistry. 285, 38, p. 29319-29325 7 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT

Lee, J. H. & Chung, I. K., 2010 Apr 1, In : Cancer Letters. 290, 1, p. 76-86 11 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Cytoskeletal keratin glycosylation protects epithelial tissue from injury

Ku, N. O., Toivola, D. M., Strnad, P. & Omary, M. B., 2010 Sep, In : Nature Cell Biology. 12, 9, p. 876-885 10 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Data management and functional annotation of the Korean reference plasma proteome

Jeong, S. K., Lee, E. Y., Cho, J. Y., Lee, H. J., Jeong, A. S., Cho, S. Y. & Paik, Y. K., 2010 Mar, In : Proteomics. 10, 6, p. 1250-1255 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Differentiation linked regulation of telomerase activity by Makorin-1

Salvatico, J., Kim, J. H., Chung, I. K. & Muller, M. T., 2010 Sep, In : Molecular and Cellular Biochemistry. 342, 1-2, p. 241-250 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)