Interdisciplinary Program of Integrated OMICS for Biomedical Sciences

Research Output

2005

Epac1-mediated Rap1 activation is not required for the production of nitric oxide in BV2, murine microglial cells

Moon, E. Y., Oh, S. Y., Han, G. H., Lee, C. S. & Park, S. K., 2005 Jul 1, In : Journal of Neuroscience Research. 81, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Interactions between subunits of Drosophila Mediator and activator proteins

Kim, Y. J. & Lis, J. T., 2005 May, In : Trends in Biochemical Sciences. 30, 5, p. 245-249 5 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)

Keratins as susceptibility genes for end-stage liver disease

Ku, N. O., Lim, J. K., Krams, S. M., Esquivel, C. O., Keeffe, E. B., Wright, T. L., Parry, D. A. D. & Omary, M. B., 2005 Sep, In : Gastroenterology. 129, 3, p. 885-893 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Methylation of CpG islands in the rat 7-dehydrocholesterol reductase promoter suppresses transcriptional activation

Kim, J. H., Hwang, E. H., Park, H. J., Paik, Y. K. & Shim, Y. H., 2005, In : Molecules and cells. 19, 2, p. 279-282 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Overview of innate immunity in Drosophila

Kim, T. & Kim, Y. J., 2005, In : Journal of biochemistry and molecular biology. 38, 2, p. 121-127 7 p.

Research output: Contribution to journalReview article

Open Access
71 Citations (Scopus)

Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database

Omenn, G. S., States, D. J., Adamski, M., Blackwell, T. W., Menon, R., Hermjakob, H., Apweiler, R., Haab, B. B., Simpson, R. J., Eddes, J. S., Kapp, E. A., Moritz, R. L., Chan, D. W., Rai, A. J., Admon, A., Aebersold, R., Eng, J., Hancock, W. S., Hefta, S. A., Meyer, H. & 20 others, Paik, Y. K., Yoo, J. S., Ping, P., Pounds, J., Adkins, J., Qian, X., Wang, R., Wasinger, V., Wu, C. Y., Zhao, X., Zeng, R., Archakov, A., Tsugita, A., Beer, I., Pandey, A., Pisano, M., Andrews, P., Tammen, H., Speicher, D. W. & Hanash, S. M., 2005 Aug, In : Proteomics. 5, 13, p. 3226-3245 20 p.

Research output: Contribution to journalReview article

595 Citations (Scopus)

Phosphatidylinositol (3,4,5)- trisphosphate specifically intracts with the phox homology domain of phospholipase D1 and stimulates its activity

Lee, J. S., Kim, J. H., Jang, I. H., Kim, H. S., Han, J. M., Kazlauskas, A., Yagisawa, H., Suh, P. G. & Ryu, S. H., 2005 Oct 1, In : Journal of cell science. 118, 19, p. 4405-4413 9 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Requirement of tyrosylprotein sulfotransferase-A for proper cuticle formation in the nematode C. elegans

Kim, T. H., Hwang, S. B., Jeong, P. Y., Lee, J. & Cho, J. W., 2005 Jan 3, In : FEBS Letters. 579, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Screening and biotransformation of interleukin-1β converting enzyme production inhibitors from Arctii fructus

Kim, H. A., Yoon, D. Y., Lee, S. M., Baek, S. H., Han, G. H., Kho, Y. H. & Lee, C. H., 2005 Apr, In : Journal of microbiology and biotechnology. 15, 2, p. 269-273 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT

Kim, J. H., Park, S. M., Kang, M. R., Oh, S. Y., Lee, T. H., Muller, M. T. & Chung, I. K., 2005 Apr 1, In : Genes and Development. 19, 7, p. 776-781 6 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

Utility of electrophoretically derived protein mass estimates as additional constraints in proteome analysis of human serum based on MS/MS analysis

Kim, J. Y., Lee, J. H., Park, G. W., Cho, K., Kwon, K. H., Park, Y. M., Cho, S. Y., Paik, Y. K. & Yoo, J. S., 2005 Aug, In : Proteomics. 5, 13, p. 3376-3385 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2004

A novel mutation of the human 7-dehydrocholesterol reductase gene reduces enzyme activity in patients with holoprosencephaly

Shim, Y. H., Bae, S. H., Kim, J. H., Kim, K. R., Kim, C. J. & Paik, Y. K., 2004 Feb 27, In : Biochemical and Biophysical Research Communications. 315, 1, p. 219-223 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Anti-Candida activity of YH-1715R, a new triazole derivative

Park, K. S., Kang, H. I., Lee, J. W. & Paik, Y. K., 2004 Aug, In : Journal of microbiology and biotechnology. 14, 4, p. 693-697 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A simple pattern classification method for alcohol-responsive proteins that are differentially expressed in mouse brain

Park, B., Jeong, S. K., Lee, W. S., Je, K. S. & Paik, Y. K., 2004 Nov, In : Proteomics. 4, 11, p. 3369-3375 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

A strain-specific alteration of proteomic expression in mouse liver fructose 1,6-bisphosphatase isoforms by alcohol

Park, B., Oh, S. H., Seong, J. K. & Paik, Y. K., 2004 Nov, In : Proteomics. 4, 11, p. 3413-3421 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II

Bourbon, H. M., Aguilera, A., Ansari, A. Z., Asturias, F. J., Berk, A. J., Bjorklund, S., Blackwell, T. K., Borggrefe, T., Carey, M., Carlson, M., Conaway, J. W., Conaway, R. C., Emmons, S. W., Fondell, J. D., Freedman, L. P., Fukasawa, T., Gustafsson, C. M., Han, M., He, X., Herman, P. K. & 27 others, Hinnebusch, A. G., Holmberg, S., Holstege, F. C., Jaehning, J. A., Kim, Y. J., Kuras, L., Leutz, A., Lis, J. T., Meisterernest, M., Naar, A. M., Nasmyth, K., Parvin, J. D., Ptashne, M., Reinberg, D., Ronne, H., Sadowski, I., Sakurai, H., Sipiczki, M., Sternberg, P. W., Stillman, D. J., Strich, R., Struhl, K., Svejstrup, J. Q., Tuck, S., Winston, F., Roeder, R. G. & Kornberg, R. D., 2004 Jun 4, In : Molecular Cell. 14, 5, p. 553-557 5 p.

Research output: Contribution to journalLetter

186 Citations (Scopus)

Carbohydrate arrays for functional studies of carbohydrates

Shin, I., Cho, J. W. & Boo, D. W., 2004 Sep, In : Combinatorial Chemistry and High Throughput Screening. 7, 6, p. 565-574 10 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)

Characterization of single stranded telomeric DNA-binding proteins in cultured soybean (Glycine max) cells

Kwon, C., Kwon, K., Chung, I. K., Kim, S. Y., Cho, M. H. & Kang, B. G., 2004 Jun 30, In : Molecules and cells. 17, 3, p. 503-508 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Comparative proteome analysis of differentially expressed proteins induced by K+ deficiency in Arabidopsis thaliana

Jeong, G. K., Young, J. P., Jin, W. C. & Myeon, H. C., 2004 Nov, In : Proteomics. 4, 11, p. 3549-3559 11 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Disease proteomics in Korea

Paik, Y. K., 2004 Nov, In : Proteomics. 4, 11, p. 3297-3298 2 p.

Research output: Contribution to journalEditorial

DNA binding mode of the isoquinoline alkaloid berberine with the deoxyoligonucleotide d(GCCGTCGTTTTACA)2

Park, H. S., Kim, E. H., Sung, Y. H., Kang, M. R., Chung, I. K., Cheong, C. & Lee, W., 2004 Apr 20, In : Bulletin of the Korean Chemical Society. 25, 4, p. 539-544 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase

Gun, E. L., Eun, Y. Y., Chae, H. C., Lee, J., Muller, M. T. & In, K. C., 2004 Aug 13, In : Journal of Biological Chemistry. 279, 33, p. 34750-34755 6 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Identification of the functional elements in the promoter region of human DNA topoisomerase IIIβ gene

Cho, Y. H., Park, J. Y., Han, S. Y. & Chung, I. K., 2004 Sep 17, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1679, 3, p. 272-278 7 p.

Research output: Contribution to journalArticle

Interaction of an Arabidopsis RNA-binding Protein with Plant Single-stranded Telomeric DNA Modulates Telomerase Activity

Kwon, C. & Chung, I. K., 2004 Mar 26, In : Journal of Biological Chemistry. 279, 13, p. 12812-12818 7 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Isolation of two distinct populations of recombinant antibody molecules specific for rat malonyl-CoA decarboxylase from a semi-synthetic human scFv display library using Ex-phage system

Baek, H. J., Hur, B. W., Cho, J. W., Lee, H. K., Kim, N. I., Oh, M. Y. & Cha, S. H., 2004 Feb 15, In : Immunology Letters. 91, 2-3, p. 163-170 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease

Toivola, D. M., Ku, N. O., Resurreccion, E. Z., Nelson, D. R., Wright, T. L. & Omary, M. B., 2004 Aug, In : Hepatology. 40, 2, p. 459-466 8 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators

Kim, T. W., Kwon, Y. J., Kim, J. M., Song, Y. H., Kim, S. N. & Kim, Y. J., 2004 Aug 17, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 33, p. 12153-12158 6 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Molecular cloning and biochemical characterization of Candida albicans acyl-CoA:sterol acyltransferase, a potential target of antifungal agents

Kim, K. Y., Shin, Y. K., Park, J. C., Kim, J. H., Yang, H., Han, D. M. & Paik, Y. K., 2004 Jul 2, In : Biochemical and Biophysical Research Communications. 319, 3, p. 911-919 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Phosphorylation of p38 MAPK Induced by Oxidative Stress Is Linked to Activation of Both Caspase-8- and -9-mediated Apoptotic Pathways in Dopaminergic Neurons

Choi, W. S., Eom, D. S., Han, B. S., Kim, W. K., Han, B. H., Choi, E. J., Oh, T. H., Markelonis, G. J., Cho, J. W. & Oh, Y. J., 2004 May 7, In : Journal of Biological Chemistry. 279, 19, p. 20451-20460 10 p.

Research output: Contribution to journalArticle

164 Citations (Scopus)

PPARα activation abolishes LDL-stimulated IL-8 production via AP-1 deactivation in human aortic smooth muscle cells

Ryoo, S., Won, M., Kim, D. U., Kim, L., Han, G., Park, S. K., Mukaida, N., Maeng, P., Yoo, H. S. & Hoe, K. L., 2004 May 28, In : Biochemical and Biophysical Research Communications. 318, 2, p. 329-334 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Proteome analysis of differential protein expression in allergen-induced asthmatic mice lung after dexamethasone treatment

Gu, S. R., Shin, Y. H., Seo, S. W., Bo, R. Y., Yeo, S. K., Sung, J. P., Jin, W. C. & Kwack, K. B., 2004 Nov, In : Proteomics. 4, 11, p. 3318-3327 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Proteomic analysis distinguishes basaloid carcinoma as a distinct subtype of nonsmall cell lung carcinoma

Long, S. L., Kim, H., Rhee, H., Se, H. K., Dong, H. S., Kyung, Y. C., Park, K. S., Paik, Y. K., Chang, J. & Kim, H., 2004 Nov, In : Proteomics. 4, 11, p. 3394-3400 7 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Proteomic analysis of diet-induced hypercholesterolemic mice

Park, J. Y., Seong, J. K. & Paik, Y. K., 2004 Feb, In : Proteomics. 4, 2, p. 514-523 10 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Quantitative profiling of plasma peptides in asthmatic mice using liquid chromatography and mass spectrometry

Yeo, S., Gu, S. R., Kim, D. H., Jung, M. L., Seo, S. W., Jin, W. C., Kim, C. W. & Kwack, K. B., 2004 Nov, In : Proteomics. 4, 11, p. 3308-3317 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Raf-1 activation disrupts its binding to keratins during cell stress

Ku, N. O., Fu, H. & Omary, M. B., 2004 Aug 16, In : Journal of Cell Biology. 166, 4, p. 479-485 7 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Restoration of heat shock protein70 suppresses gastric mucosal inducible nitric oxide synthase expression induced by Helicobacter pylori

Yeo, M., Park, H. K., Kim, D. K., Sung, W. C., Young, S. K., Sang, Y. C., Paik, Y. K. & Hahm, K. B., 2004 Nov, In : Proteomics. 4, 11, p. 3335-3342 8 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Spectroscopic studies on interaction of protoberberines with the deoxyoligonucleotide d(GCCGTCGTTTTACA)2

Park, H. S., Kim, E. H., Kang, M. R., Chung, I. K., Cheong, C. & Lee, W., 2004 Oct 20, In : Bulletin of the Korean Chemical Society. 25, 10, p. 1559-1563 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Studying simple epithelial keratins in cells and tissues

Ku, N. O., Toivola, D. M., Zhou, Q., Tao, G. Z., Zhong, B. & Omary, M. B., 2004, In : Methods in cell biology. 2004, 78, p. 489-517 29 p.

Research output: Contribution to journalReview article

62 Citations (Scopus)

Synthesis and Glycosylation of 2′-(Benzyloxycarbonyl)benzyl Glycosides as Glycosyl Donors

Kim, K. S., Lee, M. E. & Cho, J. W., 2004 Jan 20, In : Bulletin of the Korean Chemical Society. 25, 1, p. 139-142 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Telomeric DNA damage by topoisomerase I: A possible mechanism for cell killing by camptothecin

Kang, M. R., Muller, M. T. & Chung, I. K., 2004 Mar 26, In : Journal of Biological Chemistry. 279, 13, p. 12535-12541 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Towards a proteomic analysis of atopic dermatitis: A two-dimensional- polyacrylamide gel electrophoresis/mass spectrometric analysis of cultured patient-derived fibroblasts

Park, Y. D., Kim, S. Y., Jang, H. S., Seo, E. Y., Namkung, J. H., Park, K. S., Sang, Y. C., Paik, Y. K. & Yang, J. M., 2004 Nov, In : Proteomics. 4, 11, p. 3446-3455 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2003

1 H, 13C and 15N resonance assignments of rice telomere binding domain from Oryza sativa [2]

Ko, S. G., Shin, J., Yu, E. Y., Chung, I. K., Tanaka, T. & Lee, W., 2003 Sep 1, In : Journal of Biomolecular NMR. 27, 1, p. 89-90 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

A fluorescent natural product for ultra sensitive detection of proteins in one-dimensional and two-dimensional gel electrophoresis

Mackintosh, J. A., Choi, H. Y., Bae, S. H., Veal, D. A., Bell, P. J., Ferrari, B. C., Van Dyk, D. D., Verrills, N. M., Paik, Y. K. & Karuso, P., 2003 Dec, In : Proteomics. 3, 12, p. 2273-2288 16 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

A New Horizon of Proteomics in Korea

Paik, Y. K., 2003 Dec, In : Proteomics. 3, 12, p. 2271-2272 2 p.

Research output: Contribution to journalArticle

Deprotection of benzyl and p-methoxybenzyl ethers by chlorosulfonyl isocyanate-sodium hydroxide

Kim, J. D., Han, G., Zee, O. P. & Jung, Y. H., 2003 Jan 20, In : Tetrahedron Letters. 44, 4, p. 733-735 3 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Differential expression of the liver proteome in senescence accelerated mice

Cho, Y. M., Bae, S. H., Choi, B. K., Cho, S. Y., Song, C. W., Yoo, J. K. & Paik, Y. K., 2003 Oct, In : Proteomics. 3, 10, p. 1883-1894 12 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation

Kim, M. J., Park, B. J., Kang, Y. S., Kim, H. J., Park, J. H., Kang, J. W., Lee, S. W., Han, J. M., Lee, H. W. & Kim, S., 2003 Jul 1, In : Nature Genetics. 34, 3, p. 330-336 7 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)

Down-regulation of Sp1 Activity through Modulation of O-Glycosylation by Treatment with a Low Glucose Mimetic, 2-Deoxyglucose

Kang, H. T., Ju, J. W., Cho, J. W. & Hwang, E. S., 2003 Dec 19, In : Journal of Biological Chemistry. 278, 51, p. 51223-51231 9 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Expression of the telomeric repeat binding factor gene NgTRF1 is closely coordinated with the cell division program in tobacco BY-2 suspension culture cells

Yang, S. W., Kim, D. H., Lee, J. J., Chun, Y. J., Lee, J. H., Kim, Y. J., Chung, I. K. & Kim, W. T., 2003 Jun 13, In : Journal of Biological Chemistry. 278, 24, p. 21395-21407 13 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)