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2000

Cadmium induces caspase-mediated cell death: Suppression by Bcl-2

Kim, M. S., Kim, B. J., Woo, H. N., Kim, K., Kim, K. B., Kim, I. K. & Jung, Y. K., 2000 Apr 7, In : Toxicology. 145, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)
2001

Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: Cleavage of the common α subunit during apoptosis

Kim, K. W., Chung, H. H., Chung, C. W., Kim, I. K., Miura, M., Wang, S., Zhu, H., Moon, K. D., Rha, G. B., Park, J. H., Jo, D. G., Woo, H. N., Song, Y. H., Kim, B. J., Yuan, J. & Jung, Y. K., 2001 Jan 18, In : Oncogene. 20, 3, p. 358-366 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2002

Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death

Kim, M. J., Jo, D. G., Hong, G. S., Kim, B. J., Lai, M., Cho, D. H., Kim, K. W., Bandyopadhyay, A., Hong, Y. M., Kim, D. H., Cho, C., Liu, J. O., Snyder, S. H. & Jung, Y. K., 2002 Jul 23, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 15, p. 9870-9875 6 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Caspase cleavage product lacking amino-terminus of IκBα sensitizes resistant cells to TNF-α and TRAIL-induced apoptosis

Kim, K. W., Kim, B. J., Chung, C. W., Jo, D. G., Kim, I. K., Song, Y. H., Kwon, Y. K., Woo, H. N. & Jung, Y. K., 2002 Apr 15, In : Journal of Cellular Biochemistry. 85, 2, p. 334-345 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Sensitizing effects of cadmium on TNF-α- and TRAIL-mediated apoptosis of NIH3T3 cells with distinct expression patterns of p53

Kim, B. J., Kim, M. S., Kim, K. B., Kim, K., Hong, Y. M., Kim, I. K., Lee, H. W. & Jung, Y. K., 2002 Sep 1, In : Carcinogenesis. 23, 9, p. 1411-1417 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2004

Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans

Cho, Y. M., Youn, B. S., Chung, S. S., Kim, K. W., Lee, H. K., Yu, K. Y., Park, H. J., Shin, H. D. & Park, K. S., 2004 Mar, In : Diabetologia. 47, 3, p. 559-565 7 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)
2005

Regulation of human resistin gene expression in cell systems: An important role of stimulatory protein 1 interaction with a common promoter polymorphic site

Chung, S. S., Choi, H. H., Kim, K. W., Cho, Y. M., Lee, H. K. & Park, K. S., 2005 Jun 1, In : Diabetologia. 48, 6, p. 1150-1158 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2006

Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations

Kwon, C. H., Zhou, J., Li, Y., Kim, K. W., Hensley, L. L., Baker, S. J. & Parada, L. F., 2006 Mar 1, In : Genesis. 44, 3, p. 130-135 6 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2007

RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease

Gold, S. J., Hoang, C. V., Potts, B. W., Porras, G., Pioli, E., Ki, W. K., Nadjar, A., Qin, C., LaHoste, G. J., Li, Q., Bioulac, B. H., Waugh, J. L., Gurevich, E., Neve, R. L. & Bezard, E., 2007 Dec 26, In : Journal of Neuroscience. 27, 52, p. 14338-14348 11 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)
2008

Central nervous system-specific knockout of steroidogenic factor 1 results in increased anxiety-like behavior

Zhao, L., Kim, K., Ikeda, Y., Anderson, K. K., Beck, L., Chase, S., Tobet, S. A. & Parker, K. L., 2008 Jun 1, In : Molecular Endocrinology. 22, 6, p. 1403-1415 13 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Steroidogenic factor 1 regulates expression of the cannabinoid receptor 1 in the ventromedial hypothalamic nucleus

Kim, K. W., Jo, Y. H., Zhao, L., Stallings, N. R., Chua, S. C. & Parker, K. L., 2008 Aug 1, In : Molecular Endocrinology. 22, 8, p. 1950-1961 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2010

CNS-specific ablation of steroidogenic factor 1 results in impaired female reproductive function

Kim, K. W., Li, S., Zhao, H., Peng, B., Tobet, S. A., Elmquist, J. K., Parker, K. L. & Zhao, L., 2010 Jun 1, In : Molecular Endocrinology. 24, 6, p. 1240-1250 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis

Xu, Y., Hill, J. W., Fukuda, M., Gautron, L., Sohn, J. W., Kim, K. W., Lee, C. E., Choi, M. J., Lauzon, D. A., Dhillon, H., Lowell, B. B., Zigman, J. M., Zhao, J. J. & Elmquist, J. K., 2010 Jul 7, In : Cell Metabolism. 12, 1, p. 88-95 8 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)
2011

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

Kim, K. W., Zhao, L., Donato, J., Kohno, D., Xu, Y., Eliasa, C. F., Lee, C., Parker, K. L. & Elmquist, J. K., 2011 Jun 28, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 26, p. 10673-10678 6 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)
2012

FOXO1 in the ventromedial hypothalamus regulates energy balance

Kim, K. W., Donato, J., Berglund, E. D., Choi, Y. H., Kohno, D., Elias, C. F., DePinho, R. A. & Elmquist, J. K., 2012 Jul 2, In : Journal of Clinical Investigation. 122, 7, p. 2578-2589 12 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)
2013

Revisiting the ventral medial nucleus of the hypothalamus: The roles of SF-1 neurons in energy homeostasis

Choi, Y. H., Fujikawa, T., Lee, J., Reuter, A. & Kim, K. W., 2013 Jun 17, In : Frontiers in Neuroscience. 7 MAY, Article 71.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2014

Dnmt3a in sim1 neurons is necessary for normal energy homeostasis

Kohno, D., Lee, S., Harper, M. J., Kim, K. W., Sone, X., Sasaki, T., Kitamura, T., Fan, G. & Elmquist, J. K., 2014 Nov 12, In : Journal of Neuroscience. 34, 46, p. 15288-15296 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Emetine enhances the tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of pancreatic cancer cells by downregulation of myeloid cell leukemia sequence-1 protein

Han, Y., Park, S., Kinyua, A. W., Andera, L., Kim, K. I. W. & Kim, I., 2014 Jan 1, In : Oncology Reports. 31, 1, p. 456-462 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Prolactin-sensitive neurons express estrogen receptor-α and depend on sex hormones for normal responsiveness to prolactin

Furigo, I. C., Kim, K., Nagaishi, V. S., Ramos-Lobo, A. M., De Alencar, A., Pedroso, J. A. B., Metzger, M. & Donato, J., 2014 May 30, In : Brain Research. 1566, p. 47-59 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2015

A novel tripeptide derived from Chlorella vulgaris regulates skin homeostasis through antioxidant activity

Han, J. G., Kulkarni, A., Jeon, J. Y., Kim, B. R., Song, M. Y., Jeong, H. Y., Yang, D. J., You, S. H., Kim, K. W., Moh, S. H. & Hwang, J. K., 2015 Jan 1, In : Science of Advanced Materials. 7, 11, p. 2476-2480 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A novel tripeptide derived from Chlorella vulgaris regulates skin homeostasis through its antioxidant function

Han, J. G., Kulkarni, A., Jeon, J. Y., Kim, B. R., Song, M. Y., Jeong, H. Y., Yang, D. J., You, S. H., Kim, K. W., Moh, S. H. & Hwang, J. K., 2015 Jan 1, In : Science of Advanced Materials. 7, 12, p. 2545-2550 6 p.

Research output: Contribution to journalArticle

Gallic acid regulates body weight and glucose homeostasis through AMPK activation

Doan, K. V., Ko, C. M., Kinyua, A. W., Yang, D. J., Choi, Y. H., Oh, I. Y., Nguyen, N. M., Ko, A., Choi, J. W., Jeong, Y., Jung, M. H., Cho, W. G., Xu, S., Park, K., Park, W. J., Choi, S. Y., Kim, H. S., Moh, S. H. & Kim, K., 2015 Jan 1, In : Endocrinology. 156, 1, p. 157-168 12 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Insulin priming effect on estradiol-induced breast cancer metabolism and growth

Wairagu, P. M., Phan, A. N. H., Kim, M. K., Han, J., Kim, H. W., Choi, J. W., Kim, K. W., Cha, S. K., Park, K. H. & Jeong, Y., 2015 Mar 1, In : Cancer Biology and Therapy. 16, 3, p. 484-492 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Mycosporine-like amino acids promote wound healing through focal adhesion kinase (FAK) and mitogen-activated protein kinases (MAP kinases) signaling pathway in keratinocytes

Choi, Y. H., Yang, D. J., Kulkarni, A., Moh, S. H. & Kim, K. W., 2015 Dec 1, In : Marine Drugs. 13, 12, p. 7055-7066 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2016

FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase

Doan, K. V., Kinyua, A. W., Yang, D. J., Ko, C. M., Moh, S. H., Shong, K. E., Kim, H., Park, S. K., Kim, D. H., Kim, I., Paik, J. H., Depinho, R. A., Yoon, S. G., Kim, I. Y., Seong, J. K., Choi, Y. H. & Kim, K. W., 2016 Sep 29, In : Nature communications. 7, 12733.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer

Phan, A. N. H., Hua, T. N. M., Kim, M. K., Vo, V. T. A., Choi, J. W., Kim, H. W., Rho, J. K., Kim, K. W. & Jeong, Y., 2016 Jan 1, In : Oncotarget. 7, 34, p. 54702-54713 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Gallic Acid Promotes Wound Healing in Normal and Hyperglucidic Conditions

Yang, D. J., Moh, S. H., Son, D. H., You, S., Kinyua, A. W., Ko, C. M., Song, M., Yeo, J., Choi, Y. H. & Kim, K. W., 2016 Jul, In : Molecules. 21, 7, 899.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neurons

Sohn, J. W., Oh, Y., Kim, K., Lee, S., Williams, K. W. & Elmquist, J. K., 2016 Aug 1, In : Molecular Metabolism. 5, 8, p. 669-679 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Leucine-enkephalin promotes wound repair through the regulation of hemidesmosome dynamics and matrix metalloprotease

Yang, D. J., Lee, K. S., Ko, C. M., Moh, S. H., Song, J., Hur, L. C., Cheon, Y. W., Yang, S. H., Choi, Y. H. & Kim, K., 2016 Feb 1, In : Peptides. 76, p. 57-64 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination

Lee, J., Yang, D. J., Lee, S., Hammer, G. D., Kim, K. W. & Elmquist, J. K., 2016 Jan 11, In : Scientific reports. 6, 19143.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Primary cilia negatively regulate melanogenesis in melanocytes and pigmentation in a human skin model

Choi, H., Shin, J. H., Kim, E. S., Park, S. J., Bae, I. H., Jo, Y. K., Jeong, I. Y., Kim, H. J., Lee, Y., Park, H. C., Jeon, H. B., Kim, K. W., Lee, T. R. & Cho, D. H., 2016 Dec, In : PloS one. 11, 12, e0168025.

Research output: Contribution to journalArticle

5 Citations (Scopus)

SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise

Fujikawa, T., Castorena, C. M., Pearson, M., Kusminski, C. M., Ahmed, N., Battiprolu, P. K., Kim, K. W., Lee, S., Hill, J. A., Scherer, P. E., Holland, W. L. & Elmquist, J. K., 2016 Nov 22, In : eLife. 5, NOVEMBER2016, e18206.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Steroidogenic factor 1 in the ventromedial nucleus of the hypothalamus regulates age-dependent obesity

Kinyua, A. W., Yang, D. J., Chang, I. & Kim, K. W., 2016 Sep, In : PloS one. 11, 9, e0162352.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2018

4-hydroxy-3-methoxycinnamic acid regulates orexigenic peptides and hepatic glucose homeostasis through phosphorylation of FoxO1

Kinyua, A. W., Ko, C. M., Doan, K. V., Yang, D. J., Huynh, M. K. Q., Moh, S. H., Choi, Y. H. & Kim, K. W., 2018 Feb 2, In : Experimental and Molecular Medicine. 50, 2, e437.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A novel peptide, nicotinyl–isoleucine–valine–histidine (Na–IVH), promotes antioxidant gene expression and wound healing in HaCaT cells

Son, D. H., Yang, D. J., Sun, J. S., Kim, S. K., Kang, N., Kang, J. Y., Choi, Y. H., Lee, J. H., Moh, S. H., Shin, D. M. & Kim, K. W., 2018 Aug 1, In : Marine Drugs. 16, 8, 262.

Research output: Contribution to journalArticle

3 Citations (Scopus)

CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes

Kim, J., Joo, S., Eom, G. H., Lee, S. H., Lee, M. A., Lee, M., Kim, K. W., Kim, D. H., Kook, H., Kwak, T. H. & Park, W. J., 2018 Nov, In : PloS one. 13, 11, e0207228.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Insulin Regulates Adrenal Steroidogenesis by Stabilizing SF-1 Activity

Kinyua, A. W., Doan, K. V., Yang, D. J., Huynh, M. K. Q., Choi, Y. H., Shin, D. M. & Kim, K. W., 2018 Dec 1, In : Scientific reports. 8, 1, 5025.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Peripheral cannabinoid 1 receptor blockade mitigates adipose tissue inflammation via NLRP3 inflammasome in mouse models of obesity

Han, J. H., Shin, H., Rho, J. G., Kim, J. E., Son, D. H., Yoon, J., Lee, Y. J., Park, J. H., Song, B. J., Choi, C. S., Yoon, S. G., Kim, I. Y., Lee, E. K., Seong, J. K., Kim, K. W. & Kim, W., 2018 Sep, In : Diabetes, Obesity and Metabolism. 20, 9, p. 2179-2189 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Serum fibroblast growth factor 21 and new-onset metabolic syndrome: KoGES-ARIRANG study

Choi, J. R., Kim, J. Y., Park, I. H., Huh, J. H., Kim, K. W., Cha, S. K., Park, K. S., Sohn, J. H., Park, J. T. & Koh, S. B., 2018 Mar, In : Yonsei medical journal. 59, 2, p. 287-293 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

TRPM3/TRPV4 regulates Ca2+-mediated RANKL/NFATc1 expression in osteoblasts

Son, A., Kang, N., Kang, J. Y., Kim, K. W., Yang, Y. M. & Shin, D. M., 2018 Nov, In : Journal of molecular endocrinology. 61, 4, p. 207-218 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2019

Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice

Nguyen, L. V., Ta, Q. V., Dang, T. B., Nguyen, P. H., Nguyen, T., Pham, T. V. H., Nguyen, T. H. T., Baker, S., Le Tran, T., Yang, D. J., Kim, K. W. & Doan, K. V., 2019 Jan 1, In : PloS one. 14, 11, e0224674.

Research output: Contribution to journalArticle

Open Access

FoxO1 regulates leptin-induced mood behavior by targeting tyrosine hydroxylase

Son, D. H., Doan, K. V., Yang, D. J., Sun, J. S., Kim, S. K., Kang, N., Kang, J. Y., Paik, J. H., DePinho, R. A., Choi, Y. H., Shin, D. M. & Kim, K. W., 2019 Feb, In : Metabolism: Clinical and Experimental. 91, p. 43-52 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access

P110β in the ventromedial hypothalamus regulates glucose and energy metabolism

Fujikawa, T., Choi, Y. H., Yang, D. J., Shin, D. M., Donato, J., Kohno, D., Lee, C. E., Elias, C. F., Lee, S. & Kim, K. W., 2019 Apr 1, In : Experimental and Molecular Medicine. 51, 4, 52.

Research output: Contribution to journalArticle

Open Access