• 5197 Citations
  • 35 h-Index
1993 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 5197 Citations
  • 35 h-Index
  • 192 Article
  • 2 Review article
  • 1 Short survey
Filter
Article
2019

A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer

Park, J., Cho, Y. H., Shin, W. J., Lee, S. K., Lee, J. H., Kim, T., Cha, P. H., Yang, J. S., Cho, J., Min, D. S., Han, G., Lee, H. Y. & Choi, K. Y., 2019 Dec 1, In : Scientific reports. 9, 1, 648.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A therapeutic strategy for chemotherapy-resistant gastric cancer via destabilization of both β-catenin and ras

Ryu, W. J., Lee, J. E., Cho, Y. H., Lee, G., Seo, M. K., Lee, S. K., Hwang, J. H., Min, D. S., Noh, S. H., Paik, S., Kim, S., Cheong, J. H. & Choi, K. Y., 2019 Apr, In : Cancers. 11, 4, 496.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer

Ro, E. J., Cho, Y. H., Jeong, W. J., Park, J. C., Min, D. S. & Choi, K. Y., 2019 Jul 30, In : Cell Communication and Signaling. 17, 1, 88.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation

Jeong, W. J., Park, J. C., Kim, W. S., Ro, E. J., Jeon, S. H., Lee, S. K., Park, Y. N., Min, D. S. & Choi, K. Y., 2019 Dec 1, In : Nature communications. 10, 1, 295.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2018

A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab

Lee, S. K., Cho, Y. H., Cha, P. H., Yoon, J. S., Ro, E. J., Jeong, W. J., Park, J., Kim, H., Il Kim, T., Min, D. S., Han, G. & Choi, K. Y., 2018 Nov 1, In : Experimental and Molecular Medicine. 50, 11, 153.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Minoxidil induction of VEGF is mediated by inhibition of HIF-prolyl hydroxylase

Yum, S., Jeong, S., Kim, D., Lee, S., Kim, W., Yoo, J. W., Kim, J. A., Kwon, O. S., Kim, D. D., Min, D. S. & Jung, Y., 2018 Jan, In : International journal of molecular sciences. 19, 1, 53.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

β-Catenin-RAS interaction serves as a molecular switch for RAS degradation via GSK3β

Lee, S. K., Jeong, W. J., Cho, Y. H., Cha, P. H., Yoon, J. S., Ro, E. J., Choi, S., Oh, J. M., Heo, Y., Kim, H., Min, D. S., Han, G., Lee, W. & Choi, K. Y., 2018 Dec, In : EMBO Reports. 19, 12, e46060.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting β-catenin and ATP-binding cassette, subfamily G, member 2

Kang, D. W., Yang, E. S., Noh, Y. N., Hwang, W. C., Jo, S. Y., Suh, Y. A., Park, W. S., Choi, K. Y. & Min, D. S., 2017 Apr 1, In : Journal of Pathology. 241, 5, p. 614-625 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Phospholipase D1 acts through Akt/TopBP1 and RB1 to regulate the E2F1-dependent apoptotic program in cancer cells

Kang, D. W., Lee, S. W., Hwang, W. C., Lee, B. H., Choi, Y. S., Suh, Y. A., Choi, K. Y. & Min, D. S., 2017 Jan 1, In : Cancer Research. 77, 1, p. 142-152 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Phospholipase D1 inhibition linked to upregulation of ICAT blocks colorectal cancer growth hyperactivated by Wnt/β-catenin and PI3K/Akt signaling

Kang, D. W., Lee, B. H., Suh, Y. A., Choi, Y. S., Jang, S. J., Kim, Y. M., Choi, K. Y. & Min, D. S., 2017 Dec 1, In : Clinical Cancer Research. 23, 23, p. 7340-7350 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Rebamipide induces the gastric mucosal protective factor, cyclooxygenase-2, via activation of 5′-AMP-activated protein kinase

Lee, S., Jeong, S., Kim, W., Kim, D., Yang, Y., Yoon, J. H., Kim, B. J., Min, D. S. & Jung, Y., 2017 Jan 29, In : Biochemical and Biophysical Research Communications. 483, 1, p. 449-455 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Stabilization of Sur8 via PKCα/δ degradation promotes transformation and migration of colorectal cancer cells

Lee, K. H., Jeong, W. J., Cha, P. H., Lee, S. K., Min, D. S. & Choi, K. Y., 2017, In : Oncotarget. 8, 70, p. 115596-115608 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway

Bae, S. Y., Byun, S., Bae, S. H., Min, D. S., Woo, H. A. & Lee, K., 2017 May 4, In : Autophagy. 13, 5, p. 820-833 14 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
2016

A translocator protein 18 kDa ligand, Ro5-4864, inhibits ATP-induced NLRP3 inflammasome activation

Lee, J. W., Kim, L. E., Shim, H. J., Kim, E. K., Hwang, W. C., Min, D. S. & Yu, S. W., 2016 Jun 3, In : Biochemical and Biophysical Research Communications. 474, 3, p. 587-593 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation

Kim, M. Y., Kim, H. Y., Hong, J., Kim, D., Lee, H., Cheong, E., Lee, Y., Roth, J., Kim, D. G., Min, D. S. & Choi, K. Y., 2016 Mar 1, In : Glia. 64, 3, p. 350-362 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Hepatitis C virus core protein enhances hepatocellular carcinoma cells to be susceptible to oncolytic vesicular stomatitis virus through down-regulation of HDAC4

Moon, J., Kaowinn, S., Cho, I. R., Min, D. S., Myung, H., Oh, S., Kaewpiboon, C., Kraemer, O. H. & Chung, Y. H., 2016 Jun 3, In : Biochemical and Biophysical Research Communications. 474, 3, p. 428-434 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Phospholipase D1 deficiency in mice causes nonalcoholic fatty liver disease via an autophagy defect

Hur, J. H., Park, S. Y., Dall'Armi, C., Lee, J. S., Di Paolo, G., Lee, H. Y., Yoon, M. S., Min, D. S. & Choi, C. S., 2016 Dec 15, In : Scientific reports. 6, 39170.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Polygonum aviculare L. And its active compounds, quercitrin hydrate, caffeic acid, and rutin, activate the Wnt/β-catenin pathway and induce cutaneous wound healing

Seo, S. H., Lee, S. H., Cha, P. H., Kim, M. Y., Min, D. S. & Choi, K. Y., 2016 May 1, In : Phytotherapy Research. 30, 5, p. 848-854 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
5 Citations (Scopus)

Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development

Park, J. C., Jeong, W. J., Kim, M. Y., Min, D. S. & Choi, K. Y., 2016, In : Journal of cell science. 129, 15, p. 2997-3007 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

Cha, P. H., Cho, Y. H., Lee, S. K., Lee, J., Jeong, W. J., Moon, B. S., Yun, J. H., Yang, J. S., Choi, S., Yoon, J., Kim, H. Y., Kim, M. Y., Kaduwal, S., Lee, W., Min, D. S., Kim, H., Han, G. & Choi, K. Y., 2016 Aug 1, In : Nature Chemical Biology. 12, 8, p. 593-600 8 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2015

CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation

Kim, H. Y., Yoon, J. Y., Yun, J. H., Cho, K. W., Lee, S. H., Rhee, Y. M., Jung, H. S., Lim, H. J., Lee, H., Choi, J., Heo, J. N., Lee, W., No, K. T., Min, D. & Choi, K. Y., 2015 Jun 1, In : Cell Death and Differentiation. 22, 6, p. 912-920 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Euodia sutchuenensis Dode extract stimulates osteoblast differentiation via Wnt/β-catenin pathway activation

Hwang, J. H., Cha, P. H., Han, G., Bach, T. T. H., Min, D. S. I. & Choi, K. Y., 2015 Jan 1, In : Experimental & molecular medicine. 47, p. e152

Research output: Contribution to journalArticle

15 Citations (Scopus)

K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

Koo, K. H., Jeong, W. J., Cho, Y. H., Park, J. C., Min, D. S. & Choi, K. Y., 2015, In : Oncotarget. 6, 25, p. 21328-21340 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Phospholipase D2 promotes degradation of hypoxia-inducible factor-1α independent of lipase activity

Park, M. H., Bae, S. S., Choi, K. Y. & Min, D. S., 2015 Jan 1, In : Experimental and Molecular Medicine. 47, 11, e196.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

Kaduwal, S., Jeong, W. J., Park, J. C., Lee, K. H., Lee, Y. M., Jeon, S. H., Lim, Y. B., Min, D. S. & Choi, K. Y., 2015, In : Oncotarget. 6, 32, p. 33091-33105 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells

Kang, D. W., Choi, C. Y., Cho, Y. H., Tian, H., Paolo, G. D., Choi, K. Y. & Min, D. S., 2015 Jul 27, In : Journal of Experimental Medicine. 212, 8, p. 1219-1237 19 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

Lee, S. H., Kim, M. Y., Kim, H. Y., Lee, Y. M., Kim, H., Nam, K. A., Roh, M. R., Min, D. S., Chung, K. Y. & Choi, K. Y., 2015 Jun 29, In : Journal of Experimental Medicine. 212, 7, p. 1061-1080 20 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
3 Citations (Scopus)
2014

CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation

Kim, H. Y., Yang, D. H., Shin, S. W., Kim, M. Y., Yoon, J. H., Kim, S., Park, H. C., Kang, D. W., Min, D., Hur, M. W. & Choi, K. Y., 2014 Feb, In : FASEB Journal. 28, 2, p. 615-626 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Differential protein expression and novel biomarkers related to 5-FU resistance in a 3D colorectal adenocarcinoma model

Lee, S. H., Nam, J. K., Park, J. K., Lee, J. H., Min, D. S. & Kuh, H. J., 2014 Oct, In : Oncology reports. 32, 4, p. 1427-1434 8 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Hovenia dulcis Thunb extract and its ingredient methyl vanillate Activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice

Cha, P. H., Shin, W., Zahoor, M., Kim, H. Y., Min, D. S. & Choi, K. Y., 2014 Jan 22, In : PloS one. 9, 1, e85546.

Research output: Contribution to journalArticle

17 Citations (Scopus)
16 Citations (Scopus)

Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells

Hwang, W. C., Kim, M. K., Song, J. H., Choi, K. Y. & Min, D. S., 2014 Jan 1, In : Experimental and Molecular Medicine. 46, 12, e124.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability

Park, M. H., Choi, K. Y., Jung, Y. & Min, D. S., 2014, In : Oncotarget. 5, 23, p. 11857-11872 16 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates

Bae, E. J., Lee, H. J., Jang, Y. H., Michael, S., Masliah, E., Min, D. S. & Lee, S. J., 2014 Jul, In : Cell Death and Differentiation. 21, 7, p. 1132-1141 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid

Han, S., Huh, J., Kim, W., Jeong, S., Min, D. S. & Jung, Y., 2014 Jan 1, In : Experimental and Molecular Medicine. 46, 12, e126.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Phospholipase D-mediated autophagic regulation is a potential target for cancer therapy

Jang, Y. H., Choi, K. Y. & Min, D. S., 2014 Apr 1, In : Cell Death and Differentiation. 21, 4, p. 533-546 14 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Role of oncogenic K-Ras in cancer stem cell activation by aberrant wnt/β-catenin signaling

Moon, B. S., Jeong, W. J., Park, J., Kim, T. I., Min, D. S. & Choi, K. Y., 2014 Feb 1, In : Journal of the National Cancer Institute. 106, 2

Research output: Contribution to journalArticle

89 Citations (Scopus)

The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity

Choi, O. M., Cho, Y. H., Choi, S., Lee, S. H., Seo, S. H., Kim, H. Y., Han, G., Min, D. S., Park, T. & Choi, K. Y., 2014 Aug, In : International Journal of Obesity. 38, 8, p. 1044-1052 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2013

Caffeic acid phenethyl ester downregulates phospholipase D1 via direct binding and inhibition of NFκB transactivation

Park, M. H., Kang, D. W., Jung, Y., Choi, K. Y. & Min, D. S., 2013 Dec 6, In : Biochemical and Biophysical Research Communications. 442, 1-2, p. 1-7 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Phospholipase d1 has a pivotal role in interleukin-1βdriven chronic autoimmune arthritis through regulation of NF-κB, hypoxia-inducible factor 1α, and foxo3a

Kang, D. W., Park, M. K., Oh, H. J., Lee, D. G., Park, S. H., Cho, M. L., Choi, K. Y. & Min, D. S., 2013 Jul 1, In : Molecular and cellular biology. 33, 14, p. 2760-2772 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Phospholipase D inhibitor enhances radiosensitivity of breast cancer cells

Son, J. C., Kang, D. W., Yang, K. M., Choi, K. Y., Son, T. G. & Min, D. S., 2013 Aug 16, In : Experimental and Molecular Medicine. 45, 8, e38.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Rebamipide abolishes Helicobacter pylori CagA-induced phospholipase D1 expression via inhibition of NFκB and suppresses invasion of gastric cancer cells

Kang, D. W., Hwang, W. C., Park, M. H., Ko, G. H., Ha, W. S., Kim, K. S., Lee, Y. C., Choi, K. Y. & Min, D. S., 2013 Jul 25, In : Oncogene. 32, 30, p. 3531-3542 12 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2012

Colon-targeted cell-permeable NFκB inhibitory peptide is orally active against experimental colitis

Hong, S., Yum, S., Yoo, H. J., Kang, S., Yoon, J. H., Min, D., Kim, Y. M. & Jung, Y., 2012 May 7, In : Molecular Pharmaceutics. 9, 5, p. 1310-1319 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Histone deacetylase inhibitor, apicidin, inhibits human ovarian cancer cell migration via class II histone deacetylase 4 silencing

Ahn, M. Y., Kang, D. O., Na, Y. J., Yoon, S., Choi, W. S., Kang, K. W., Chung, H. Y., Jung, J. H., Min, D. S. & Kim, H. S., 2012 Dec 28, In : Cancer Letters. 325, 2, p. 189-199 11 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
4 Citations (Scopus)
7 Citations (Scopus)

Valproic Acid Induces Cutaneous Wound Healing In Vivo and Enhances Keratinocyte Motility

Lee, S. H., Zahoor, M., Hwang, J. K., Min, D. S. & Choi, K. Y., 2012 Nov 7, In : PloS one. 7, 11, e48791.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells

Lee, S. H., Yoon, J., Shin, S. H., Zahoor, M., Kim, H. J., Park, P. J., Park, W. S., Min, D. S., Kim, H. Y. & Choi, K. Y., 2012 Apr 10, In : PloS one. 7, 4, e34152.

Research output: Contribution to journalArticle

50 Citations (Scopus)