• 2298 Citations
  • 22 h-Index
20042020

Research output per year

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Research Output

  • 2298 Citations
  • 22 h-Index
  • 60 Article
  • 4 Review article
2020

Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing

Kang, J. K., Heo, S., Kim, H. P., Song, S. H., Yun, H., Han, S. W., Kang, G. H., Bang, D. & Kim, T. Y., 2020 May, In : PloS one. 15, 5, e0232754.

Research output: Contribution to journalArticle

Open Access

MAPS-seq: magnetic bead-assisted parallel single-cell gene expression profiling

Park, M., Lee, D., Bang, D. & Lee, J. H., 2020 May 1, In : Experimental and Molecular Medicine. 52, 5, p. 804-814 11 p.

Research output: Contribution to journalArticle

Open Access

Multiplex generation, tracking, and functional screening of substitution mutants using a crispr/retron system

Lim, H., Jun, S., Park, M., Lim, J., Jeong, J., Lee, J. H. & Bang, D., 2020 May 15, In : ACS Synthetic Biology. 9, 5, p. 1003-1009 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Single-cell analysis of a mutant library generated using CRISPR-guided deaminase in human melanoma cells

Jun, S., Lim, H., Chun, H., Lee, J. H. & Bang, D., 2020 Dec 1, In : Communications Biology. 3, 1, 154.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2019

Applying a Linear Amplification Strategy to Recombinase Polymerase Amplification for Uniform DNA Library Amplification

Lee, J., Heo, S. & Bang, D., 2019 Nov 26, In : ACS Omega. 4, 22, p. 19953-19958 6 p.

Research output: Contribution to journalArticle

Open Access

Association of pathway mutation with survival after recurrence in colorectal cancer patients treated with adjuvant fluoropyrimidine and oxaliplatin chemotherapy

Lee, D. W., Han, S. W., Cha, Y., Bae, J. M., Kim, H. P., Lyu, J., Han, H., Kim, H., Jang, H., Bang, D., Won, J. K., Jeong, S. Y., Park, K. J., Kang, G. H. & Kim, T. Y., 2019 May 6, In : BMC cancer. 19, 1, 421.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Chimeric crRNAs with 19 DNA residues in the guide region show the retained DNA cleavage activity of Cas9 with potential to improve the specificity

Kim, H. Y., Kang, S. J., Jeon, Y., An, J., Park, J., Lee, H. J., Jang, J. E., Ahn, J. S., Bang, D., Chung, H. S., Jeong, C. & Ahn, D. R., 2019, In : Chemical Communications. 55, 24, p. 3552-3555 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

CRISPR-Cap: multiplexed double-stranded DNA enrichment based on the CRISPR system

Lee, J., Lim, H., Jang, H., Hwang, B., Lee, J. H., Cho, J., Lee, J. H. & Bang, D., 2019 Jan 10, In : Nucleic acids research. 47, 1, e1.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Facilitated Large-Scale Sequence Validation Platform Using Tn5-Tagmented Cell Lysates

Hwang, B., Heo, S., Cho, N., Seo, H. & Bang, D., 2019 Mar 15, In : ACS Synthetic Biology. 8, 3, p. 596-600 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements

Hwang, B., Lee, W., Yum, S. Y., Jeon, Y., Cho, N., Jang, G. & Bang, D., 2019 Dec 1, In : Nature communications. 10, 1, 1234.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Multiplexed single-cell RNA-seq via transient barcoding for simultaneous expression profiling of various drug perturbations

Shin, D., Lee, W., Lee, J. H. & Bang, D., 2019 May 15, In : Science Advances. 5, 5, eaav2249.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

NFATC3-PLA2G15 fusion transcript identified by RNA sequencing promotes tumor invasion and proliferation in colorectal cancer cell lines

Jang, J. E., Kim, H. P., Han, S. W., Jang, H., Lee, S. H., Song, S. H., Bang, D. & Kim, T. Y., 2019 Jan 1, In : Cancer Research and Treatment. 51, 1, p. 391-401 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Tumor mutation burden and prognosis in patients with colorectal cancer treated with adjuvant fluoropyrimidine and oxaliplatin

Lee, D. W., Han, S. W., Bae, J. M., Jang, H., Han, H., Kim, H., Bang, D., Jeong, S. Y., Park, K. J., Kang, G. H. & Kim, T. Y., 2019 Oct 15, In : Clinical Cancer Research. 25, 20, p. 6141-6147 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2018

Highly selective retrieval of accurate DNA utilizing a pool of in situ-replicated DNA from multiple next-generation sequencing platforms

Lim, H., Cho, N., Ahn, J., Park, S., Jang, H., Kim, H., Han, H., Lee, J. H. & Bang, D., 2018, In : Nucleic acids research. 46, 7, e40.

Research output: Contribution to journalArticle

2 Citations (Scopus)

High-throughput construction of multiple cas9 gene variants via assembly of high-depth tiled and sequence-verified oligonucleotides

Cho, N., Seo, H. N., Ryu, T., Kwon, E., Huh, S., Noh, J., Yeom, H., Hwang, B., Ha, H., Lee, J. H., Kwon, S. & Bang, D., 2018 May, In : Nucleic acids research. 46, 9, e55.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Selective targeting of KRAS oncogenic alleles by CRISPR/Cas9 inhibits proliferation of cancer cells

Lee, W., Lee, J. H., Jun, S., Lee, J. H. & Bang, D., 2018 Dec 1, In : Scientific reports. 8, 1, 11879.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Single-cell RNA sequencing technologies and bioinformatics pipelines

Hwang, B., Lee, J. H. & Bang, D., 2018 Aug 1, In : Experimental and Molecular Medicine. 50, 8, 96.

Research output: Contribution to journalReview article

172 Citations (Scopus)

Straightforward Delivery of Linearized Double-Stranded DNA Encoding sgRNA and Donor DNA for the Generation of Single Nucleotide Variants Based on the CRISPR/Cas9 System

Jun, S., Lim, H., Jang, H., Lee, W., Ahn, J., Lee, J. H. & Bang, D., 2018 Jul 20, In : ACS Synthetic Biology. 7, 7, p. 1651-1659 9 p.

Research output: Contribution to journalArticle

2017

Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer

Lee, D. W., Han, S. W., Cha, Y., Bae, J. M., Kim, H. P., Lyu, J., Han, H., Kim, H., Jang, H., Bang, D., Huh, I., Park, T., Won, J. K., Jeong, S. Y., Park, K. J., Kang, G. H. & Kim, T. Y., 2017 Sep 15, In : Cancer. 123, 18, p. 3513-3523 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Asymmetrical barcode adapterassisted recovery of duplicate reads and error correction strategy to detect rare mutations in circulating tumor DNA

Ahn, J., Byungjin, H., Kim, H. Y., Hoon, J., Kim, H. P., Han, S. W., Kim, T. Y., Lee, J. H. & Bang, D., 2017 May 2, In : Scientific reports. 7, 46678.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians, but not in Caucasians

Kim, S. Y., Kim, K., Hwang, B., Im, K., Park, S. N., Kim, J. A., Hwang, S. M., Bang, D. & Lee, D. S., 2017 Oct, In : Leukemia Research. 61, p. 96-103 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification

Lee, S. Y., Kim, K. R., Bang, D., Bae, S. W., Kim, H. J. & Ahn, D. R., 2016 Sep, In : Biomaterials Science. 4, 9, p. 1314-1317 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Clinical and pathological heterogeneity of Korean patients with CAPN3 mutations

Park, H. J., Jang, H., Lee, J. H., Shin, H. Y., Cho, S. R., Park, K. D., Bang, D., Lee, M. G., Kim, S. M., Lee, J. H. & Choi, Y. C., 2016 Jan, In : Yonsei medical journal. 57, 1, p. 173-179 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

FOXC2 and CLIP4: A potential biomarker for synchronous metastasis of ≤7-cm clear cell renal cell carcinomas

Ahn, J., Han, K. S., Heo, J. H., Bang, D., Kang, Y. H., Jin, H. A., Hong, S. J., Lee, J. H. & Ham, W. S., 2016 Aug 1, In : Oncotarget. 7, 32, p. 51423-51434 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Genomic profile of chronic lymphocytic leukemia in Korea identified by targeted sequencing

Kim, J. A., Hwang, B., Park, S. N., Huh, S., Im, K., Choi, S., Chung, H. Y., Huh, J. R., Seo, E. J., Lee, J. H., Bang, D. & Lee, D. S., 2016 Dec, In : PloS one. 11, 12, e0167641.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Nano-formulation of a photosensitizer using a DNA tetrahedron and its potential for in vivo photodynamic therapy

Kim, K. R., Bang, D. & Ahn, D. R., 2016 Apr, In : Biomaterials Science. 4, 4, p. 605-609 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs

Kim, K. R., Kim, H. Y., Lee, Y. D., Ha, J. S., Kang, J. H., Jeong, H., Bang, D., Ko, Y. T., Kim, S., Lee, H. & Ahn, D. R., 2016 Dec 10, In : Journal of Controlled Release. 243, p. 121-131 11 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer

Ahn, J., Kim, K. H., Park, S., Ahn, Y. H., Kim, H. Y., Yoon, H., Lee, J. H., Bang, D. & Lee, D. H., 2016, In : Oncotarget. 7, 39, p. 63252-63260 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Toward a new paradigm of DNA writing using a massively parallel sequencing platform and degenerate oligonucleotide

Hwang, B. & Bang, D., 2016 Nov 23, In : Scientific reports. 6, 37176.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2015

A high-throughput optomechanical retrieval method for sequence-verified clonal DNA from the NGS platform

Lee, H., Kim, H., Kim, S., Ryu, T., Kim, H., Bang, D. & Kwon, S., 2015 Feb, In : Nature communications. 6, 6073.

Research output: Contribution to journalArticle

15 Citations (Scopus)

De novo assembly and next-generation sequencing to analyse full-length gene variants from codon-barcoded libraries

Cho, N., Hwang, B., Yoon, J. K., Park, S., Lee, J., Seo, H. N., Lee, J., Huh, S., Chung, J. & Bang, D., 2015 Sep 21, In : Nature communications. 6, 8351.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Genetic testing of Korean Familial hypercholesterolemia using whole-exome sequencing

Han, S. M., Hwang, B., Park, T. G., Kim, D. I., Rhee, M. Y., Lee, B. K., Ahn, Y. K., Cho, B. R., Woo, J., Hur, S. H., Jeong, J. O., Park, S., Jang, Y., Lee, M. G., Bang, D., Lee, J. H. & Lee, S. H., 2015 May 11, In : PloS one. 10, 5, e0126706.

Research output: Contribution to journalArticle

9 Citations (Scopus)

MicroDuMIP: Target-enrichment technique for microarray-based duplex Molecular inversion probes

Yoon, J. K., Ahn, J., Kim, H. S., Han, S. M., Jang, H., Lee, M. G., Lee, J. H. & Bang, D., 2015 Mar 11, In : Nucleic acids research. 43, 5, e28.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Repetitive genomic insertion of gene-sized dsDNAs by targeting the promoter region of a counter-selectable marker

Jeong, J., Seo, H. N., Jung, Y. K., Lee, J., Ryu, G., Lee, W., Kwon, E., Ryoo, K., Kim, J., Cho, H. Y., Cho, K. M., Park, J. H. & Bang, D., 2015, In : Scientific reports. 5, 8712.

Research output: Contribution to journalArticle

Targeted next-generation sequencing for the genetic diagnosis of dysferlinopathy

Shin, H. Y., Jang, H., Han, J. H., Park, H. J., Lee, J. H., Kim, S. W., Kim, S. M., Park, Y. E., Kim, D. S., Bang, D., Lee, M. G., Lee, J. H. & Choi, Y. C., 2015 Jun 1, In : Neuromuscular Disorders. 25, 6, p. 502-510 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing

Lee, J. Y., Yoon, J. K., Kim, B., Kim, S., Kim, M. A., Lim, H., Bang, D. & Song, Y. S., 2015 Feb 26, In : BMC cancer. 15, 1, 85.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2014

Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers

Ahn, J. W., Kim, H. S., Yoon, J. K., Jang, H., Han, S. M., Eun, S., Shim, H. S., Kim, H. J., Kim, D. J., Lee, J. G., Lee, C. Y., Bae, M. K., Chung, K. Y., Jung, J. Y., Kim, E. Y., Kim, S. K., Chang, J., Kim, H. R., Kim, J. H., Lee, M. G. & 3 others, Cho, B. C., Lee, J. H. & Bang, D., 2014 Feb 27, In : Genome Medicine. 6, 2, 18.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Novel fusion transcripts in human gastric cancer revealed by transcriptome analysis

Kim, H. P., Cho, G. A., Han, S. W., Shin, J. Y., Jeong, E. G., Song, S. H., Lee, W. C., Lee, K. H., Bang, D., Seo, J. S., Kim, J. I. & Kim, T. Y., 2014 Nov 20, In : Oncogene. 33, 47, p. 5434-5441 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2013

A library of TAL effector nucleases spanning the human genome

Kim, Y., Kweon, J., Kim, A., Chon, J. K., Yoo, J. Y., Kim, H. J., Kim, S., Lee, C., Jeong, E., Chung, E., Kim, D., Lee, M. S., Go, E. M., Song, H. J., Kim, H., Cho, N., Bang, D., Kim, S. & Kim, J. S., 2013 Mar, In : Nature Biotechnology. 31, 3, p. 251-258 8 p.

Research output: Contribution to journalArticle

245 Citations (Scopus)

Genome-scale genetic engineering in Escherichia coli

Jeong, J., Cho, N., Jung, D. & Bang, D., 2013 Nov 1, In : Biotechnology Advances. 31, 6, p. 804-810 7 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)

The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma

Kim, H. R., Ahn, J. R., Lee, J. G., Bang, D. H., Ha, S. J., Hong, Y. K., Kim, S. M., Nam, K. C., Rha, S. Y., Soo, R. A., Riely, G. J., Kim, J. H. & Cho, B. C., 2013 Jul, In : Yonsei medical journal. 54, 4, p. 865-874 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Total chemical synthesis of fully functional Photoactive Yellow Protein

Gordon, W. R., Bang, D., Hoff, W. D. & Kent, S. B. H., 2013 Jun 15, In : Bioorganic and Medicinal Chemistry. 21, 12, p. 3436-3442 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2012

Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology

Mandal, K., Pentelute, B. L., Bang, D., Gates, Z. P., Torbeev, V. Y. & Kent, S. B. H., 2012 Feb 6, In : Angewandte Chemie - International Edition. 51, 6, p. 1481-1486 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Genome-scale promoter engineering by coselection MAGE

Wang, H. H., Kim, H., Cong, L., Jeong, J., Bang, D. & Church, G. M., 2012 Jun, In : Nature Methods. 9, 6, p. 591-593 3 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)

'Shotgun DNA synthesis' for the high-throughput construction of large DNA molecules

Kim, H., Han, H., Ahn, J., Lee, J., Cho, N., Jang, H., Kim, H., Kwon, S. & Bang, D., 2012 Oct, In : Nucleic acids research. 40, 18, p. e140

Research output: Contribution to journalArticle

27 Citations (Scopus)

Through the looking glass - a new world of proteins enabled by chemical synthesis

Kent, S., Sohma, Y., Liu, S., Bang, D., Pentelute, B. & Mandal, K., 2012 Jul, In : Journal of Peptide Science. 18, 7, p. 428-436 9 p.

Research output: Contribution to journalReview article

30 Citations (Scopus)
2011

Hierarchical gene synthesis using DNA microchip oligonucleotides

Kim, H., Jeong, J. & Bang, D., 2011 Feb 20, In : Journal of Biotechnology. 151, 4, p. 319-324 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Multiple target loci assembly sequencing (mTAS)

Han, H., Yoon, J. K., Cho, B. C., Kim, H. & Bang, D., 2011 Aug 15, In : Analytical Biochemistry. 415, 2, p. 218-220 3 p.

Research output: Contribution to journalArticle

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement

Isaacs, F. J., Carr, P. A., Wang, H. H., Lajoie, M. J., Sterling, B., Kraal, L., Tolonen, A. C., Gianoulis, T. A., Goodman, D. B., Reppas, N. B., Emig, C. J., Bang, D., Hwang, S. J., Jewett, M. C., Jacobson, J. M. & Church, G. M., 2011 Jul 15, In : Science. 333, 6040, p. 348-353 6 p.

Research output: Contribution to journalArticle

354 Citations (Scopus)