• 5799 Citations
  • 41 h-Index
1988 …2020

Research output per year

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Research Output

2020

Artifact-free and high-temporal-resolution in vivo opto-electrophysiology with microLED optoelectrodes

Kim, K., Vöröslakos, M., Seymour, J. P., Wise, K. D., Buzsáki, G. & Yoon, E., 2020 Dec 1, In : Nature communications. 11, 1, 2063.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Early Prediction of Single-Cell Derived Sphere Formation Rate Using Convolutional Neural Network Image Analysis

Chen, Y. C., Chen, Y. C., Zhang, Z., Yoon, E., Yoon, E. & Yoon, E., 2020 Jun 2, In : Analytical Chemistry. 92, 11, p. 7717-7724 8 p.

Research output: Contribution to journalArticle

Microfluidic high-throughput cell pairing and retrieval for studying breast cancer-MSC engulfment

Chen, Y. C., Gonzalez, M. E., Hiziroglu, A. B., Zhao, X., Brien, R., Cheng, Y. H., Zhang, Z., Kleer, C. G. & Yoon, E., 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 171-172 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Novel diamond shuttle to deliver flexible neural probe with reduced tissue compression

Na, K., Sperry, Z. J., Lu, J., Vöröslakos, M., Parizi, S. S., Bruns, T. M., Yoon, E. & Seymour, J. P., 2020 Dec 1, In : Microsystems and Nanoengineering. 6, 1, 37.

Research output: Contribution to journalArticle

Open Access
2019

A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs

Belur Nagaraj, A., Joseph, P., Ponting, E., Fedorov, Y., Singh, S., Cole, A., Lee, W., Yoon, E., Baccarini, A., Scacheri, P., Buckanovich, R., Adams, D. J., Drapkin, R., Brown, B. D. & DiFeo, A., 2019 Jan 8, In : Stem Cell Reports. 12, 1, p. 122-134 13 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells

Chefetz, I., Grimley, E., Yang, K., Hong, L., Vinogradova, E. V., Suciu, R., Kovalenko, I., Karnak, D., Morgan, C. A., Chtcherbinine, M., Buchman, C., Huddle, B., Barraza, S., Morgan, M., Bernstein, K. A., Yoon, E., Lombard, D. B., Bild, A., Mehta, G., Romero, I. & 6 others, Chiang, C. Y., Landen, C., Cravatt, B., Hurley, T. D., Larsen, S. D. & Buckanovich, R. J., 2019 Mar 12, In : Cell Reports. 26, 11, p. 3061-3075.e6

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Co-culture of functionally enriched cancer stem-like cells and cancer-associated fibroblasts for single-cell whole transcriptome analysis

Chen, Y. C., Jung, S., Zhang, Z., Wicha, M. S. & Yoon, E., 2019 Dec 31, In : Integrative biology : quantitative biosciences from nano to macro. 11, 9, p. 353-361 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells

Cheng, Y. H., Chen, Y. C., Lin, E., Brien, R., Jung, S., Chen, Y. T., Lee, W., Hao, Z., Sahoo, S., Min Kang, H., Cong, J., Burness, M., Nagrath, S., S. Wicha, M. & Yoon, E., 2019 Dec 1, In : Nature communications. 10, 1, 2163.

Research output: Contribution to journalArticle

Open Access
26 Citations (Scopus)

Label-Free Estimation of Therapeutic Efficacy on 3D Cancer Spheres Using Convolutional Neural Network Image Analysis

Zhang, Z., Chen, L., Wang, Y., Zhang, T., Chen, Y. C. & Yoon, E., 2019 Nov 5, In : Analytical Chemistry. 91, 21, p. 14093-14100 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Low-power, bio-inspired time-stamp-based 2-d optic flow sensor for artificial compound eyes of micro air vehicles

Park, S., Lee, K., Song, H., Cho, J., Park, S. Y. & Yoon, E., 2019 Dec 15, In : IEEE Sensors Journal. 19, 24, p. 12059-12068 10 p., 8821370.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer

Chen, Y. C., Gonzalez, M. E., Burman, B., Zhao, X., Anwar, T., Tran, M., Medhora, N., Hiziroglu, A. B., Lee, W., Cheng, Y. H., Choi, Y., Yoon, E. & Kleer, C. G., 2019 Jun 25, In : Cell Reports. 27, 13, p. 3916-3926.e5

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Microneedle Penetrating Array with Axon-Sized Dimensions for Cuff-less Peripheral Nerve Interfacing

Yan, D., Jiman, A., Ratze, D., Huang, S., Parizi, S., Welle, E., Ouyang, Z., Patel, P., Kushner, M. J., Chestek, C., Bruns, T. M., Yoon, E. & Seymour, J., 2019 May 16, 9th International IEEE EMBS Conference on Neural Engineering, NER 2019. IEEE Computer Society, p. 827-830 4 p. 8717097. (International IEEE/EMBS Conference on Neural Engineering, NER; vol. 2019-March).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Plasminogen activator inhibitor 1 (PAI1) promotes actin cytoskeleton reorganization and glycolytic metabolism in triple-negative breast cancer

Humphries, B. A., Buschhaus, J. M., Chen, Y. C., Haley, H. R., Qyli, T., Chiang, B., Shen, N., Rajendran, S., Cutter, A., Cheng, Y. H., Chen, Y. T., Cong, J., Spinosa, P. C., Yoon, E., Luker, K. E. & Luker, G. D., 2019 May, In : Molecular Cancer Research. 17, 5, p. 1142-1154 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Single-cell proteolytic activity measurement using microfluidics for rare cell populations

Chen, Y. C. & Yoon, E., 2019, Methods in Enzymology. Allbritton, N. L. & Kovarik, M. L. (eds.). Academic Press Inc., p. 129-143 15 p. (Methods in Enzymology; vol. 628).

Research output: Chapter in Book/Report/Conference proceedingChapter

Single-cell RNA-sequencing of migratory breast cancer cells: Discovering genes associated with cancer metastasis

Chen, Y. C., Sahoo, S., Brien, R., Jung, S., Humphries, B., Lee, W., Cheng, Y. H., Zhang, Z., Luker, K. E., Wicha, M. S., Luker, G. D. & Yoon, E., 2019 Dec 21, In : Analyst. 144, 24, p. 7296-7309 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Ultracompliant Carbon Nanotube Direct Bladder Device

Yan, D., Bruns, T. M., Wu, Y., Zimmerman, L. L., Stephan, C., Cameron, A. P., Yoon, E. & Seymour, J. P., 2019 Oct 1, In : Advanced Healthcare Materials. 8, 20, 1900477.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

4.32-pJ/b, Overlap-Free, Feedforward Edge-Combiner-Based Ultra-Wideband Transmitter for High-Channel-Count Neural Recording

Lin, Y. J., Park, S. Y., Chen, X., Wentzloff, D. & Yoon, E., 2018 Jan, In : IEEE Microwave and Wireless Components Letters. 28, 1, p. 52-54 3 p., 8170259.

Research output: Contribution to journalArticle

6 Citations (Scopus)

A Battery-Powered Opto-Electrophysiology Neural Interface with Artifact-Preventing Optical Pulse Shaping

Mendrela, A. E., Park, S. Y., Vöröslakos, M., Flynn, M. P. & Yoon, E., 2018 Oct 22, 2018 IEEE Symposium on VLSI Circuits, VLSI Circuits 2018. Institute of Electrical and Electronics Engineers Inc., p. 125-126 2 p. 8502353. (IEEE Symposium on VLSI Circuits, Digest of Technical Papers; vol. 2018-June).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

A High-Resolution Opto-Electrophysiology System with a Miniature Integrated Headstage

Mendrela, A. E., Kim, K., English, D., McKenzie, S., Seymour, J. P., Buzsaki, G. & Yoon, E., 2018 Oct, In : IEEE Transactions on Biomedical Circuits and Systems. 12, 5, p. 1065-1075 11 p., 8411136.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A miniature headstage for high resolution closed-loop optogenetics

Mendrela, A. E., Kim, K., English, D., McKenzie, S., Seymour, J., Buzsáki, G. & Yoon, E., 2018 Mar 23, 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 1-4 4 p. (2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings; vol. 2018-January).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Deep learning correlates single-cell morphology with migratory behaviors in microfluidics

Zhang, Z., Chen, L., Chen, Y. C. & Yoon, E., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 331-332 2 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dual color optogenetic control of neural populations using low-noise, multishank optoelectrodes

Kampasi, K., English, D. F., Seymour, J., Stark, E., McKenzie, S., Vöröslakos, M., Buzsáki, G., Wise, K. D. & Yoon, E., 2018 Dec 1, In : Microsystems and Nanoengineering. 4, 1, 10.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Dynamic Power Reduction in Scalable Neural Recording Interface Using Spatiotemporal Correlation and Temporal Sparsity of Neural Signals

Park, S. Y., Cho, J., Lee, K. & Yoon, E., 2018 Apr, In : IEEE Journal of Solid-State Circuits. 53, 4, p. 1102-1114 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Flexible microelectrode array for interfacing with the surface of neural ganglia

Sperry, Z. J., Na, K., Parizi, S. S., Chiel, H. J., Seymour, J., Yoon, E. & Bruns, T. M., 2018 Apr 16, In : Journal of Neural Engineering. 15, 3, 036027.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Functional Isolation of Tumor-Initiating Cells using Microfluidic-Based Migration Identifies Phosphatidylserine Decarboxylase as a Key Regulator

Chen, Y. C., Humphries, B., Brien, R., Gibbons, A. E., Chen, Y. T., Qyli, T., Haley, H. R., Pirone, M. E., Chiang, B., Xiao, A., Cheng, Y. H., Luan, Y., Zhang, Z., Cong, J., Luker, K. E., Luker, G. D. & Yoon, E., 2018 Dec 1, In : Scientific reports. 8, 1, 244.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Minimally-invasive neural interface for distributed wireless electrocorticogram recording systems

Chang, S. I., Park, S. Y. & Yoon, E., 2018 Jan 17, In : Sensors (Switzerland). 18, 1, 263.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Modular 128-Channel Δ - ΔΣ Analog Front-End Architecture Using Spectrum Equalization Scheme for 1024-Channel 3-D Neural Recording Microsystems

Park, S. Y., Cho, J., Na, K. & Yoon, E., 2018 Feb, In : IEEE Journal of Solid-State Circuits. 53, 2, p. 501-514 14 p., 8100720.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Morphology-based prediction of cancer cell migration using an artificial neural network and a random decision forest

Zhang, Z., Chen, L., Humphries, B., Brien, R., Wicha, M. S., Luker, K. E., Luker, G. D., Chen, Y. C. & Yoon, E., 2018 Dec, In : Integrative Biology (United Kingdom). 10, 12, p. 758-767 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

P38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis

Anwar, T., Arellano-Garcia, C., Ropa, J., Chen, Y. C., Kim, H. S., Yoon, E., Grigsby, S., Basrur, V., Nesvizhskii, A. I., Muntean, A., Gonzalez, M. E., Kidwell, K. M., Nikolovska-Coleska, Z. & Kleer, C. G., 2018 Dec 1, In : Nature communications. 9, 1, 2801.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Scalable Multiplexed Drug-Combination Screening Platforms Using 3D Microtumor Model for Precision Medicine

Zhang, Z., Chen, Y. C., Urs, S., Chen, L., Simeone, D. M. & Yoon, E., 2018 Oct 18, In : Small. 14, 42, 1703617.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Simultaneous Imaging and Energy Harvesting in CMOS Image Sensor Pixels

Park, S. Y., Lee, K., Song, H. & Yoon, E., 2018 Apr, In : IEEE Electron Device Letters. 39, 4, p. 532-535 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney

Menon, R., Otto, E. A., Kokoruda, A., Zhou, J., Zhang, Z., Yoon, E., Chen, Y. C., Troyanskaya, O., Spence, J. R., Kretzler, M. & Cebriań, C., 2018 Aug, In : Development (Cambridge). 145, 16 Special Issue, dev164038.

Research output: Contribution to journalArticle

Open Access
36 Citations (Scopus)

Single-cell RNA-sequencing of migratory cancer cells sorted by microfluidics: Discovering drivers of cancer metastasis

Chen, Y. C., Brien, R., Sahoo, S., Lee, W., Cheng, Y. H., Jung, S., Haley, H., Luker, K., Luker, G. & Yoon, E., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 130-131 2 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2017

3.37 μw/Ch modular scalable neural recording system with embedded lossless compression for dynamic power reduction

Park, S. Y., Cho, J. & Yoon, E., 2017 Aug 10, 2017 Symposium on VLSI Circuits, VLSI Circuits 2017. Institute of Electrical and Electronics Engineers Inc., p. C168-C169 8008468. (IEEE Symposium on VLSI Circuits, Digest of Technical Papers).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

A 272.49 pJ/pixel CMOS image sensor with embedded object detection and bio-inspired 2D optic flow generation for nano-air-vehicle navigation

Lee, K., Park, S., Park, S. Y., Cho, J. & Yoon, E., 2017 Aug 10, 2017 Symposium on VLSI Circuits, VLSI Circuits 2017. Institute of Electrical and Electronics Engineers Inc., p. C294-C295 8008514. (IEEE Symposium on VLSI Circuits, Digest of Technical Papers).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications

Lee, S. Y., Na, K., Pakela, J. M., Scheiman, J. M., Yoon, E. & Mycek, M. A., 2017, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV. Grundfest, W. S., Vo-Dinh, T. & Mahadevan-Jansen, A. (eds.). SPIE, 100540Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10054).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Compliant ultrasound proximity sensor for the safe operation of human friendly robots integrated with tactile sensing capability

Cho, I. J., Lee, H. K., Chang, S. I. & Yoon, E., 2017, In : Journal of Electrical Engineering and Technology. 12, 1, p. 310-316 7 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Endothelial-derived interleukin-6 induces cancer stem cell motility by generating a chemotactic gradient towards blood vessels

Kim, H. S., Chen, Y. C., Nör, F., Warner, K. A., Andrews, A., Wagner, V. P., Zhang, Z., Zhang, Z., Martins, M. D., Pearson, A. T., Yoon, E. & Nör, J. E., 2017, In : Oncotarget. 8, 59, p. 100339-100352 14 p.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

High-throughput cancer cell sphere formation for 3D cell culture

Chen, Y. C. & Yoon, E., 2017, Methods in Molecular Biology. Humana Press Inc., p. 281-291 11 p. (Methods in Molecular Biology; vol. 1612).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Low-power low-noise pseudo-open-loop preamplifier for neural interfaces

Chang, S. I., Park, S. Y. & Yoon, E., 2017 Aug 1, In : IEEE Sensors Journal. 17, 15, p. 4843-4852 10 p., 7953634.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth

Gonzalez, M. E., Martin, E. E., Anwar, T., Arellano-Garcia, C., Medhora, N., Lama, A., Chen, Y. C., Tanager, K. S., Yoon, E., Kidwell, K. M., Ge, C., Franceschi, R. T. & Kleer, C. G., 2017 Jan 31, In : Cell Reports. 18, 5, p. 1215-1228 14 p.

Research output: Contribution to journalArticle

Open Access
40 Citations (Scopus)

Pyramidal Cell-Interneuron Circuit Architecture and Dynamics in Hippocampal Networks

English, D. F., McKenzie, S., Evans, T., Kim, K., Yoon, E. & Buzsáki, G., 2017 Oct 11, In : Neuron. 96, 2, p. 505-520.e7

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)

Sampling from single-cell observations to predict tumor cell growth in-vitro and in-vivo

Pearson, A. T., Ingram, P., Bai, S., O'Hayer, P., Chung, J., Yoon, E., Jackson, T. & Buckanovich, R. J., 2017, In : Oncotarget. 8, 67, p. 111176-111189 14 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Selective Photomechanical Detachment and Retrieval of Divided Sister Cells from Enclosed Microfluidics for Downstream Analyses

Chen, Y. C., Baac, H. W., Lee, K. T., Fouladdel, S., Teichert, K., Ok, J. G., Cheng, Y. H., Ingram, P. N., Hart, A. J., Azizi, E., Guo, L. J., Wicha, M. S. & Yoon, E., 2017 May 23, In : ACS Nano. 11, 5, p. 4660-4668 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

State-of-the-art mems and microsystem tools for brain research

Seymour, J. P., Wu, F., Wise, K. D. & Yoon, E., 2017, In : Microsystems and Nanoengineering. 3, 16066.

Research output: Contribution to journalArticle

Open Access
59 Citations (Scopus)
2016

A 12,800-well single-cell-derived sphere assay chip utilizing highly-parallel microfluidic structures for cancer heterogeneity studies

Cheng, Y. H., Chen, Y. C., Brien, R. & Yoon, E., 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 238-239 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A Bidirectional Neural Interface Circuit with Active Stimulation Artifact Cancellation and Cross-Channel Common-Mode Noise Suppression

Mendrela, A. E., Cho, J., Fredenburg, J. A., Nagaraj, V., Netoff, T. I., Flynn, M. P. & Yoon, E., 2016 Apr, In : IEEE Journal of Solid-State Circuits. 51, 4, p. 955-965 11 p., 7370773.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Chronic In Vivo evaluation of PEDOT/CNT for stable neural recordings

Kozai, T. D. Y., Catt, K., Du, Z., Na, K., Srivannavit, O., Haque, R. U. M., Seymour, J., Wise, K. D., Yoon, E. & Cui, X. T., 2016 Jan, In : IEEE Transactions on Biomedical Engineering. 63, 1, p. 111-119 9 p., 2445713.

Research output: Contribution to journalArticle

73 Citations (Scopus)

EGFL6 regulates the asymmetric division, maintenance, and metastasis of ALDH+ ovarian cancer cells

Bai, S., Ingram, P., Chen, Y. C., Deng, N., Pearson, A., Niknafs, Y., O'Hayer, P., Wang, Y., Zhang, Z. Y., Boscolo, E., Bischoff, J., Yoon, E. & Buckanovich, R. J., 2016 Nov 1, In : Cancer Research. 76, 21, p. 6396-6409 14 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)

Fiberless multicolor neural optoelectrode for in vivo circuit analysis

Kampasi, K., Stark, E., Seymour, J., Na, K., Winful, H. G., Buzsáki, G., Wise, K. D. & Yoon, E., 2016 Aug 3, In : Scientific reports. 6, 30961.

Research output: Contribution to journalArticle

Open Access
46 Citations (Scopus)