• 3124 Citations
  • 22 h-Index
20092019

Research output per year

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Research Output

  • 3124 Citations
  • 22 h-Index
  • 24 Article
  • 4 Review article
  • 2 Short survey
  • 1 Comment/debate
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Article

Alternative Wnt Signaling Activates YAP/TAZ

Park, H. W., Kim, Y. C., Yu, B., Moroishi, T., Mo, J. S., Plouffe, S. W., Meng, Z., Lin, K. C., Yu, F. X., Alexander, C. M., Wang, C. Y. & Guan, K. L., 2015 Aug 17, In : Cell. 162, 4, p. 780-794 15 p., 8328.

Research output: Contribution to journalArticle

235 Citations (Scopus)

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

Moroishi, T., Park, H. W., Qin, B., Chen, Q., Meng, Z., Plouffe, S. W., Taniguchi, K., Yu, F. X., Karin, M., Pan, D. & Guan, K. L., 2015 Jun 15, In : Genes and Development. 29, 12, p. 1271-1284 14 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

Mo, J. S., Meng, Z., Kim, Y. C., Park, H. W., Hansen, C. G., Kim, S., Lim, D. S. & Guan, K. L., 2015 Apr 30, In : Nature Cell Biology. 17, 4, p. 500-510 11 p.

Research output: Contribution to journalArticle

196 Citations (Scopus)

Differential regulation of mTORC1 by leucine and glutamine

Jewell, J. L., Kim, Y. C., Russell, R. C., Yu, F. X., Park, H. W., Plouffe, S. W., Tagliabracci, V. S. & Guan, K. L., 2015 Jan 9, In : Science. 347, 6218, p. 194-198 5 p.

Research output: Contribution to journalArticle

286 Citations (Scopus)

Dynamic modulation of ANO1/TMEM16A HCO3- permeability by Ca2+/calmodulin

Jung, J., Nam, J. H., Park, H. W., Oh, U., Yoon, J. H. & Lee, M. G., 2013 Jan 2, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. 360-365 6 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

Dynamic regulation of CFTR bicarbonate permeability by [Cl -]i and its role in pancreatic bicarbonate secretion

Park, H. W., Nam, J. H., Kim, J. Y., Namkung, W., Yoon, J. S., Lee, J. S., Kim, K. S., Venglovecz, V., Gray, M. A., Kim, K. H. & Lee, M. G., 2010, In : Gastroenterology. 139, 2, p. 620-631 12 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

EIF5A-PEAK1 signaling regulates YAP1/TAZ protein expression and pancreatic cancer cell growth

Strnadel, J., Choi, S., Fujimura, K., Wang, H., Zhang, W., Wyse, M., Wright, T., Gross, E., Peinado, C., Park, H. W., Bui, J., Kelber, J., Bouvet, M., Guan, K. L. & Klemke, R. L., 2017 Apr 15, In : Cancer Research. 77, 8, p. 1997-2007 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Expression of anion exchangers in cultured human endolymphatic sac epithelia

Lee, H. J., Yang, W. S., Park, H. W., Choi, H. S., Kim, S. H., Kim, J. Y. & Choi, J. Y., 2012 Dec 1, In : Otology and Neurotology. 33, 9, p. 1664-1671 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway

Meng, Z., Moroishi, T., Mottier-Pavie, V., Plouffe, S. W., Hansen, C. G., Hong, A. W., Park, H. W., Mo, J. S., Lu, W., Lu, S., Flores, F., Yu, F. X., Halder, G. & Guan, K. L., 2015 Oct 5, In : Nature communications. 6, 8357.

Research output: Contribution to journalArticle

162 Citations (Scopus)

Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis

LaRusch, J., Jung, J., General, I. J., Lewis, M. D., Park, H. W., Brand, R. E., Gelrud, A., Anderson, M. A., Banks, P. A., Conwell, D., Lawrence, C., Romagnuolo, J., Baillie, J., Alkaade, S., Cote, G., Gardner, T. B., Amann, S. T., Slivka, A., Sandhu, B., Aloe, A. & 6 others, Kienholz, M. L., Yadav, D., Barmada, M. M., Bahar, I., Lee, M. G. & Whitcomb, D. C., 2014 Jul, In : PLoS Genetics. 10, 7, e1004376.

Research output: Contribution to journalArticle

76 Citations (Scopus)

MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity

Lee, I. Y., Lim, J. M., Cho, H., Kim, E., Kim, Y., Oh, H. K., Yang, W. S., Roh, K. H., Park, H. W., Mo, J. S., Yoon, J. H., Song, H. K. & Choi, E. J., 2019 Mar 21, In : Molecular Cell. 73, 6, p. 1138-1149.e6

Research output: Contribution to journalArticle

6 Citations (Scopus)

Opposite regulatory effects of TRPC1 and TRPC5 on neurite outgrowth in PC12 cells

Heo, D. K., Chung, W. Y., Park, H. W., Yuan, J. P., Lee, M. G. & Kim, J. Y., 2012 Apr 1, In : Cellular Signalling. 24, 4, p. 899-906 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

Yu, F. X., Zhang, Y., Park, H. W., Jewell, J. L., Chen, Q., Deng, Y., Pan, D., Taylor, S. S., Lai, Z. C. & Guan, K. L., 2013 Feb 1, In : Genes and Development. 27, 11, p. 1223-1232 10 p.

Research output: Contribution to journalArticle

159 Citations (Scopus)

Rag GTPases are cardioprotective by regulating lysosomal function

Kim, Y. C., Park, H. W., Sciarretta, S., Mo, J. S., Jewell, J. L., Russell, R. C., Wu, X., Sadoshima, J. & Guan, K. L., 2014 Jul 1, In : Nature communications. 5, 4241.

Research output: Contribution to journalArticle

44 Citations (Scopus)

RAP2 mediates mechanoresponses of the Hippo pathway

Meng, Z., Qiu, Y., Lin, K. C., Kumar, A., Placone, J. K., Fang, C., Wang, K. C., Lu, S., Pan, M., Hong, A. W., Moroishi, T., Luo, M., Plouffe, S. W., Diao, Y., Ye, Z., Park, H. W., Wang, X., Yu, F. X., Chien, S., Wang, C. Y. & 3 others, Ren, B., Engler, A. J. & Guan, K. L., 2018 Aug 30, In : Nature. 560, 7720, p. 655-660 6 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation

Lin, K. C., Moroishi, T., Meng, Z., Jeong, H. S., Plouffe, S. W., Sekido, Y., Han, J., Park, H. W. & Guan, K. L., 2017 Aug 1, In : Nature Cell Biology. 19, 8, p. 996-1002 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Rescue of epithelial HCO 3 - secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del

Xiao, F., Li, J., Singh, A. K., Riederer, B., Wang, J., Sultan, A., Park, H., Lee, M. G., Lamprecht, G., Scholte, B. J., De Jonge, H. R. & Seidler, U., 2012 Nov 1, In : Journal of Physiology. 590, 21, p. 5317-5334 18 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature

Park, H. W., Kim, J. Y., Choi, S. K., Lee, Y. H., Zeng, W., Kim, K. H., Muallem, S. & Lee, M. G., 2011 Jun 28, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 26, p. 10750-10755 6 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Synaptic Scaffolding Molecule Binds to and Regulates Vasoactive Intestinal Polypeptide Type-1 Receptor in Epithelial Cells

Gee, H. Y., Kim, Y. W., Jo, M. J., Namkung, W., Kim, J. Y., Park, H. W., Kim, K. S., Kim, H., Baba, A., Yang, J., Kim, E., Kim, K. H. & Lee, M. G., 2009 Aug, In : Gastroenterology. 137, 2, p. 607-617.e4

Research output: Contribution to journalArticle

24 Citations (Scopus)

Transepithelial bicarbonate secretion: Lessons from the pancreas

Park, H. W. & Lee, M. G., 2012 Oct, In : Cold Spring Harbor Perspectives in Medicine. 2, 10, a009571.

Research output: Contribution to journalArticle

20 Citations (Scopus)

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

Russell, R. C., Tian, Y., Yuan, H., Park, H. W., Chang, Y. Y., Kim, J., Kim, H., Neufeld, T. P., Dillin, A. & Guan, K. L., 2013 Jul 1, In : Nature Cell Biology. 15, 7, p. 741-750 10 p.

Research output: Contribution to journalArticle

715 Citations (Scopus)

WNK4 inhibits plasma membrane targeting of NCC through regulation of syntaxin13 SNARE formation

Chung, W. Y., Park, H. W., Han, J. W., Lee, M. G. & Kim, J. Y., 2013 Dec, In : Cellular Signalling. 25, 12, p. 2469-2477 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

WNK4 kinase negatively regulates the surface expression of Muscarinic M3 receptor

Chung, W. Y., Park, H. W., Heo, D. K., Kim, K. H., Lee, M. G. & Kim, J. Y., 2011 Mar 1, In : Cellular Signalling. 23, 3, p. 566-571 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

βpix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction

Lee, J. S., Lee, Y. M., Kim, J. Y., Park, H. W., Grinstein, S., Orlowski, J., Kim, E., Kim, K. H. & Lee, M. G., 2010 Mar 12, In : Journal of Biological Chemistry. 285, 11, p. 8104-8113 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)