• 9316 Citations
  • 45 h-Index
1990 …2020

Research output per year

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Research Output

A chemodosimeter approach to fluorescent sensing and imaging of inorganic and methylmercury species

Santra, M., Ryu, D., Chatterjee, A., Ko, S. K., Shin, I. & Ahn, K. H., 2009, In : Chemical Communications. 16, p. 2115-2117 3 p.

Research output: Contribution to journalArticle

158 Citations (Scopus)

A cyanine-based fluorescent sensor for detecting endogenous zinc ions in live cells and organisms

Guo, Z., Kim, G. H., Shin, I. & Yoon, J., 2012 Nov 1, In : Biomaterials. 33, 31, p. 7818-7827 10 p.

Research output: Contribution to journalArticle

133 Citations (Scopus)

A Glycoengineered Enzyme with Multiple Mannose-6-Phosphates Is Internalized into Diseased Cells to Restore Its Activity in Lysosomes

Hyun, J. Y., Kim, S., Lee, H. S. & Shin, I., 2018 Oct 18, In : Cell Chemical Biology. 25, 10, p. 1255-1267.e8

Research output: Contribution to journalArticle

8 Citations (Scopus)

A lysosomal chloride ion-selective fluorescent probe for biological applications

Park, S. H., Hyun, J. Y. & Shin, I., 2019, In : Chemical Science. 10, 1, p. 56-66 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Analysis of binding properties of pathogens and toxins using multivalent glycan microarrays

Kim, H. S., Hyun, J. Y., Park, S. H. & Shin, I., 2018, In : RSC Advances. 8, 27, p. 14898-14905 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Analysis of density-dependent binding of glycans by lectins using carbohydrate microarrays

Tian, X., Pai, J. & Shin, I., 2012 Sep 1, In : Chemistry - An Asian Journal. 7, 9, p. 2052-2060 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Analysis of Protein-Protein Interaction in a Single Live Cell by Using a FRET System Based on Genetic Code Expansion Technology

Park, S. H., Ko, W., Lee, H. S. & Shin, I., 2019 Mar 13, In : Journal of the American Chemical Society. 141, 10, p. 4273-4281 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Analysis of the role of the active site tyrosine in human glutathione transferase A1-1 by unnatural amino acid mutagenesis

Thorson, J. S., Shin, I., Chapman, E., Stenberg, G., Mannervik, B. & Schultz, P. G., 1998 Jan 21, In : Journal of the American Chemical Society. 120, 2, p. 451-452 2 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

An apoptosis-inducing small molecule that binds to heat shock protein 70

Williams, D. R., Ko, S. K., Park, S., Lee, M. R. & Shin, I., 2008 Sep 15, In : Angewandte Chemie - International Edition. 47, 39, p. 7466-7469 4 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

A near-infrared fluorescent sensor for detection of cyanide in aqueous solution and its application for bioimaging

Chen, X., Nam, S. W., Kim, G. H., Song, N., Jeong, Y., Shin, I., Kim, S. K., Kim, J., Park, S. & Yoon, J., 2010 Dec 21, In : Chemical Communications. 46, 47, p. 8953-8955 3 p.

Research output: Contribution to journalArticle

262 Citations (Scopus)

A new efficient method for the synthesis of L-galactose [5]

Kim, K. S., Cho, B. H. & Shin, I., 2002 Sep 20, In : Bulletin of the Korean Chemical Society. 23, 9, p. 1193-1194 2 p.

Research output: Contribution to journalLetter

10 Citations (Scopus)

An Inhibitor of the Interaction of Survivin with Smac in Mitochondria Promotes Apoptosis

Park, S. H., Shin, I., Park, S. H., Kim, N. D. & Shin, I., 2019 Nov 18, In : Chemistry - An Asian Journal. 14, 22, p. 4035-4041 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

An NBD-based colorimetric and fluorescent chemosensor for Zn2+ and its use for detection of intracellular zinc ions

Xu, Z., Kim, G. H., Han, S. J., Jou, M. J., Lee, C., Shin, I. & Yoon, J., 2009 Mar 14, In : Tetrahedron. 65, 11, p. 2307-2312 6 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)

Anti-leukemia activity of a Hsp70 inhibitor and its hybrid molecules

Park, S. H., Kim, W. J., Li, H., Seo, W., Park, S. H., Kim, H., Shin, S. C., Zuiderweg, E. R. P., Kim, E. E. K., Sim, T., Kim, N. K. & Shin, I., 2017 Dec 1, In : Scientific reports. 7, 1, 3537.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A pH-sensitive excited state intramolecular proton transfer fluorescent probe for imaging mitochondria and Helicobacter pylori

Hong, K. I., Park, S. H., Lee, S. M., Shin, I. & Jang, W. D., 2019 May 1, In : Sensors and Actuators, B: Chemical. 286, p. 148-153 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neurons

Kim, B. S., Lee, C. H., Chang, G. E., Cheong, E. & Shin, I., 2016 Sep 29, In : Scientific reports. 6, 34324.

Research output: Contribution to journalArticle

16 Citations (Scopus)

A rhodamine-hydroxamic acid-based fluorescent probe for hypochlorous acid and its applications to Biological imagings

Yang, Y. K., Cho, H. J., Lee, J., Shin, I. & Tae, J., 2009 Feb 19, In : Organic Letters. 11, 4, p. 859-861 3 p.

Research output: Contribution to journalArticle

240 Citations (Scopus)

A selenolactone-based fluorescent chemodosimeter to monitor mecury/methylmercury species in vitro and in vivo

Chen, X., Baek, K. H., Kim, Y., Kim, S. J., Shin, I. & Yoon, J., 2010 Jun 5, In : Tetrahedron. 66, 23, p. 4016-4021 6 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

A Sex Pheromone Isolated from Macrocentrus grandii. Absolute Stereochemistry Determination and Implications

Shin, I., Zhou, H. Q., Que, N. L. S., Liu, H. W., Swedenborg, P. D. & Jones, R. L., 1993 Jan 1, In : Journal of Organic Chemistry. 58, 10, p. 2923-2926 4 p.

Research output: Contribution to journalComment/debate

16 Citations (Scopus)

A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens

Baek, K. H., Zhang, H., Lee, B. R., Kwon, Y. G., Ha, S. J. & Shin, I., 2015 Dec 3, In : Scientific reports. 5, 17642.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A small molecule inhibitor of ATPase activity of HSP70 induces apoptosis and has antitumor activities

Ko, S. K., Kim, J., Na, D. C., Park, S., Park, S. H., Hyun, J. Y., Baek, K. H., Kim, N. D., Kim, N. K., Park, Y. N., Song, K. & Shin, I., 2015 Mar 19, In : Chemistry and Biology. 22, 3, p. 391-403 13 p., 3008.

Research output: Contribution to journalArticle

42 Citations (Scopus)

A small molecule that binds to an ATPase domain of Hsc70 promotes membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator

Cho, H. J., Gee, H. Y., Baek, K. H., Ko, S. K., Park, J. M., Lee, H., Kim, N. D., Lee, M. G. & Shin, I., 2011 Dec 21, In : Journal of the American Chemical Society. 133, 50, p. 20267-20276 10 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations

Busschaert, N., Park, S. H., Baek, K. H., Choi, Y. P., Park, J., Howe, E. N. W., Hiscock, J. R., Karagiannidis, L. E., Marques, I., Félix, V., Namkung, W., Sessler, J. L., Gale, P. A. & Shin, I., 2017 Jul 1, In : Nature chemistry. 9, 7, p. 667-675 9 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

A thiol-specific fluorescent probe and its application for bioimaging

Chen, X., Ko, S. K., Kim, M. J., Shin, I. & Yoon, J., 2010, In : Chemical Communications. 46, 16, p. 2751-2753 3 p.

Research output: Contribution to journalArticle

256 Citations (Scopus)

Autophagy-regulating small molecules and their therapeutic applications

Baek, K. H., Park, J. & Shin, I., 2012 Mar 23, In : Chemical Society reviews. 41, 8, p. 3245-3263 19 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Biological activity of (3 R,5 S,6 R)- and (3 S,5 R,6 S)-3,5-dimethyl-6-(methylethyl)-3,4,5,6-tetrahydropyran-2-one, a pheromone of Macrocentrus grandii (Goidanich) (Hymenoptera: Braconidae)

Swedenborg, P. D., Jones, R. L., Zhou, H. Q., Shin, I. & Liu, H. W., 1994 Dec 1, In : Journal of Chemical Ecology. 20, 12, p. 3373-3380 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Boronic acid-linked fluorescent and colorimetric probes for copper ions

Swamy, K. M. K., Ko, S. K., Kwon, S. K., Lee, H. N., Mao, C., Kim, J. M., Lee, K. H., Kim, J., Shin, I. & Yoon, J., 2008, In : Chemical Communications. 45, p. 5915-5917 3 p.

Research output: Contribution to journalArticle

232 Citations (Scopus)

Carbohydrate Analogue Microarrays for Identification of Lectin-Selective Ligands

Hyun, J. Y., Park, C. W., Liu, Y., Kwon, D., Park, S. H., Park, S., Pai, J. & Shin, I., 2017 Jun 19, In : ChemBioChem. 18, 12, p. 1077-1082 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Carbohydrate arrays for functional studies of carbohydrates

Shin, I., Cho, J. W. & Boo, D. W., 2004 Sep, In : Combinatorial Chemistry and High Throughput Screening. 7, 6, p. 565-574 10 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)

Carbohydrate chemistry

Shin, I. & Soo Kima, K., 2013 Apr 29, In : Chemical Society reviews. 42, 10, p. 4267-4269 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Carbohydrate Chips for Studying High-Throughput Carbohydrate-Protein Interactions

Park, S., Lee, M. R., Pyo, S. J. & Shin, I., 2004 Apr 21, In : Journal of the American Chemical Society. 126, 15, p. 4812-4819 8 p.

Research output: Contribution to journalArticle

204 Citations (Scopus)

Carbohydrate microarrays: An advanced technology for functional studies of glycans

Shin, I., Park, S. & Lee, M. R., 2005 May 6, In : Chemistry - A European Journal. 11, 10, p. 2894-2901 8 p.

Research output: Contribution to journalArticle

153 Citations (Scopus)

Carbohydrate microarrays

Park, S., Gildersleeve, J. C., Blixt, O. & Shin, I., 2013 Apr 29, In : Chemical Society reviews. 42, 10, p. 4310-4326 17 p.

Research output: Contribution to journalArticle

171 Citations (Scopus)

Carbohydrate microarrays as powerful tools in studies of carbohydrate-mediated biological processes

Park, S., Lee, M. R. & Shin, I., 2008, In : Chemical Communications. 37, p. 4389-4399 11 p.

Research output: Contribution to journalReview article

79 Citations (Scopus)

Carbohydrate microarrays containing glycosylated fluorescent probes for assessment of glycosidase activities

Hyun, J. Y., Kang, N. R. & Shin, I., 2018 Feb 16, In : Organic Letters. 20, 4, p. 1240-1243 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Carbohydrate microarrays for assaying galactosyltransferase activity

Park, S. & Shin, I., 2007 Apr 26, In : Organic Letters. 9, 9, p. 1675-1678 4 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Carbohydrate microarrays for enzymatic reactions and quantification of binding affinities for glycan-protein interactions

Lee, M. R., Park, S. & Shin, I., 2012 Jan 1, Carbohydrate Microarrays: Methods and Protocols. Chevolot, Y. (ed.). p. 103-116 14 p. (Methods in Molecular Biology; vol. 808).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)

Carbohydrate microarrays for screening functional glycans

Pai, J., Hyun, J. Y., Jeong, J., Loh, S., Cho, E. H., Kang, Y. S. & Shin, I., 2016 Mar 1, In : Chemical Science. 7, 3, p. 2084-2093 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Cardiosulfa, a small molecule that induces abnormal heart development in zebrafish, and its biological implications

Ko, S. K., Jin, H. J., Jung, D. W., Tian, X. & Shin, I., 2009 Oct 5, In : Angewandte Chemie - International Edition. 48, 42, p. 7809-7812 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Cardiosulfa Induces Heart Deformation in Zebrafish through the AhR-Mediated, CYP1A-Independent Pathway

Ko, S. K. & Shin, I., 2012 Jul 9, In : ChemBioChem. 13, 10, p. 1483-1489 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
4 Citations (Scopus)

Chemical tools for functional studies of glycans

Park, S., Lee, M. R. & Shin, I., 2008 Jul 22, In : Chemical Society reviews. 37, 8, p. 1579-1591 13 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
9 Citations (Scopus)

Chemoselective ligation of maleimidosugars to peptides/protein for the preparation of neoglycopeptides/neoglycoprotein

Shin, I., Jung, H. J. & Lee, M. R., 2001 Feb 12, In : Tetrahedron Letters. 42, 7, p. 1325-1328 4 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Cobalt-catalyzed asymmetric addition of silylacetylenes to oxa- and azabenzonorbornadienes

Shin, I., 2012 May 21, In : Chemical Communications. 48, 48, p. 5956-5967 2 p.

Research output: Contribution to journalArticle

Cobalt-catalyzed asymmetric addition of silylacetylenes to oxa- and azabenzonorbornadienes

Guo, Z., Shin, I. & Yoon, J., 2012 May 21, In : Chemical Communications. 48, 48, p. 5956-5967 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Combining Suppression of Stemness with Lineage-Specific Induction Leads to Conversion of Pluripotent Cells into Functional Neurons

Halder, D., Chang, G. E., De, D., Cheong, E., Kim, K. K. & Shin, I., 2015 Nov 19, In : Chemistry and Biology. 22, 11, p. 1512-1520 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Construction of carbohydrate microarrays by using one-step, direct immobilizations of diverse unmodified glycans on solid surfaces

Park, S., Lee, M. R. & Shin, I., 2009 Jan 1, In : Bioconjugate Chemistry. 20, 1, p. 155-162 8 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

CycIobutaneacetyl-CoA: A Janus-Faced Substrate for Acyl-CoA Dehydrogenases

Shin, I., Li, D., Becker, D. F., Stankovich, M. T. & Liu, H. W., 1994 Sep 1, In : Journal of the American Chemical Society. 116, 19, p. 8843-8844 2 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

De novo design of non-hydrogen-bonded helical pseudopeptides composed of oxanipecotic acid oligomers

Lee, M. R., Kim, K. Y., Cho, U. I., Boo, D. W. & Shin, I., 2003 Jan 1, In : Chemical Communications. 3, 8, p. 968-969 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)