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Research Output 2002 2019

Article

AAVR-Displaying Interfaces: Serotype-Independent Adeno-Associated Virus Capture and Local Delivery Systems

Kim, S. H., Lee, S., Lee, H., Cho, M., Schaffer, D. V. & Jang, J. H., 2019 Dec 6, In : Molecular Therapy - Nucleic Acids. 18, p. 432-443 12 p.

Research output: Contribution to journalArticle

Open Access
Dependovirus
Biocompatible Materials
Click Chemistry
Genes
Viral Genes
59 Citations (Scopus)

An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells

Jang, J. H., Koerber, J. T., Kim, J. S., Asuri, P., Vazin, T., Bartel, M., Keung, A., Kwon, I., Park, K. I. & Schaffer, D. V., 2011 Apr, In : Molecular Therapy. 19, 4, p. 667-675 9 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Gene Targeting
Stem Cells
Genes
Cell Biology
14 Citations (Scopus)

Bicomponent electrospinning to fabricate three-dimensional hydrogel-hybrid nanofibrous scaffolds with spatial fiber tortuosity

Jin, G., Lee, S., Kim, S. H., Kim, M. & Jang, J-H., 2014 Oct 30, In : Biomedical Microdevices. 16, 6, p. 793-804 12 p.

Research output: Contribution to journalArticle

Hydrogel
Electrospinning
Hydrogels
Scaffolds
Pyrrolidinones
14 Citations (Scopus)

Colloids as mobile substrates for the implantation and integration of differentiated neurons into the mammalian brain

Jgamadze, D., Bergen, J., Stone, D., Jang, J. H., Schaffer, D. V., Isacoff, E. Y. & Pautot, S., 2012 Jan 25, In : PloS one. 7, 1, e30293.

Research output: Contribution to journalArticle

colloids
Colloids
Ion implantation
Neurons
Brain
127 Citations (Scopus)

Controllable delivery of non-viral DNA from porous scaffolds

Jang, J. H. & Shea, L. D., 2003 Jan 9, In : Journal of Controlled Release. 86, 1, p. 157-168 12 p.

Research output: Contribution to journalArticle

Microspheres
DNA
Polymers
Tissue Engineering
Emulsions
1 Citation (Scopus)

Development of efficient adeno-associated virus (AAV)-mediated gene delivery system with a phytoactive material for targeting human melanoma cells

Lee, J. H., Kim, Y., Yoon, Y. E., Kim, Y. J., Oh, S. G., Jang, J-H. & Kim, E., 2017 Jul 25, In : New Biotechnology. 37, p. 194-199 6 p.

Research output: Contribution to journalArticle

Gene therapy
Gene Transfer Techniques
Heparan Sulfate Proteoglycans
Dependovirus
Cell death
72 Citations (Scopus)

Directed evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells

Asuri, P., Bartel, M. A., Vazin, T., Jang, J. H., Wong, T. B. & Schaffer, D. V., 2012 Feb, In : Molecular Therapy. 20, 2, p. 329-338 10 p.

Research output: Contribution to journalArticle

Dependovirus
Pluripotent Stem Cells
Gene Targeting
Genes
Zinc Fingers
99 Citations (Scopus)

DNA shuffling of adeno-associated virus yields functionally diverse viral progeny

Koerber, J. T., Jang, J. H. & Schaffer, D. V., 2008 Aug 28, In : Molecular Therapy. 16, 10, p. 1703-1709 7 p.

Research output: Contribution to journalArticle

DNA Shuffling
Dependovirus
Libraries
Genes
Viruses
28 Citations (Scopus)

Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression

Kim, E., Song, I. T., Lee, S., Kim, J. S., Lee, H. & Jang, J. H., 2012 Jun 4, In : Angewandte Chemie - International Edition. 51, 23, p. 5598-5601 4 p.

Research output: Contribution to journalArticle

Polyetherimides
Viruses
Gene expression
Catecholamines
Adhesives
17 Citations (Scopus)

Elastin-like polypeptide matrices for enhancing adeno-associated virus-mediated gene delivery to human neural stem cells

Kim, J. S., Chu, H. S., Park, K. I., Won, J. I. & Jang, J. H., 2012 Mar 1, In : Gene Therapy. 19, 3, p. 329-337 9 p.

Research output: Contribution to journalArticle

Dependovirus
Neural Stem Cells
Elastin
Peptides
Genes
29 Citations (Scopus)

Electrospun nanofibrous scaffolds for controlled release of adeno-associated viral vectors

Lee, S., Kim, J. S., Chu, H. S., Kim, G. W., Won, J. I. & Jang, J. H., 2011 Nov 1, In : Acta Biomaterialia. 7, 11, p. 3868-3876 9 p.

Research output: Contribution to journalArticle

Elastin
Polypeptides
Scaffolds
Dependovirus
Scaffolds (biology)
36 Citations (Scopus)

Engineering adeno-associated virus for one-step purification via immobilized metal affinity chromatography

Koerber, J. T., Jang, J. H., Yu, J. H., Kane, R. S. & Schaffer, D. V., 2007 Apr 1, In : Human Gene Therapy. 18, 4, p. 367-378 12 p.

Research output: Contribution to journalArticle

His-His-His-His-His-His
Dependovirus
Affinity Chromatography
Capsid
Metals
1 Citation (Scopus)

Enhanced Cell Adhesion on a Nano-Embossed, Sticky Surface Prepared by the Printing of a DOPA-Bolaamphiphile Assembly Ink

Lee, C., Kim, S. H., Jang, J. H. & Lee, S. Y., 2017 Dec 1, In : Scientific reports. 7, 1, 13797.

Research output: Contribution to journalArticle

Dihydroxyphenylalanine
Cell adhesion
Ink
Printing
Self assembly

Enhanced cellular secretion of AAV2 by expression of foreign viral envelope proteins

Kotterman, M. A., Koerber, J. T., Nam, J. S., Cho, Y. H., Kim, S. H., Jang, J. H. & Lim, K. I., 2015 Jan 5, In : Biochemical Engineering Journal. 93, p. 108-114 7 p.

Research output: Contribution to journalArticle

Viral Envelope Proteins
Dependovirus
Viruses
Virion
Exosomes
2 Citations (Scopus)

Enhanced cellular transfection by ternary non-viral gene vectors coupled with adeno-associated virus-derived peptides

Oh, J. S., Park, M., Kim, J. S. & Jang, J-H., 2014 Jan 1, In : Macromolecular Bioscience. 14, 1, p. 121-130 10 p.

Research output: Contribution to journalArticle

Dependovirus
Viruses
Peptides
Transfection
Genes
2 Citations (Scopus)

Functional Polysaccharide Sutures Prepared by Wet Fusion of Interfacial Polyelectrolyte Complexation Fibers

Do, M., Im, B. G., Park, J. P., Jang, J-H. & Lee, H., 2017 Nov 10, In : Advanced Functional Materials. 27, 42, 1702017.

Research output: Contribution to journalArticle

polysaccharides
Polysaccharides
Polyelectrolytes
Complexation
Fusion reactions
107 Citations (Scopus)

Gene delivery through cell culture substrate adsorbed DNA complexes

Bengali, Z., Pannier, A. K., Segura, T., Anderson, B. C., Jang, J. H., Mustoe, T. A. & Shea, L. D., 2005 May 5, In : Biotechnology and Bioengineering. 90, 3, p. 290-302 13 p.

Research output: Contribution to journalArticle

Cell culture
Polystyrenes
Biocompatible Materials
DNA
Cell Culture Techniques
25 Citations (Scopus)

Heparin-coated superparamagnetic nanoparticle-mediated adeno-associated virus delivery for enhancing cellular transduction

Hwang, J. H., Lee, S., Kim, E., Kim, J. S., Lee, C. H., Ahn, I. S. & Jang, J. H., 2011 Dec 15, In : International Journal of Pharmaceutics. 421, 2, p. 397-404 8 p.

Research output: Contribution to journalArticle

Dependovirus
Nanoparticles
Heparin
Nerve Growth Factor
Gene Transfer Techniques
24 Citations (Scopus)

Highly moldable electrospun clay-like fluffy nanofibers for three-dimensional scaffolds

Lee, S., Cho, S., Kim, M., Jin, G., Jeong, U. & Jang, J-H., 2014 Jan 22, In : ACS Applied Materials and Interfaces. 6, 2, p. 1082-1091 10 p.

Research output: Contribution to journalArticle

Nanofibers
Scaffolds
Clay
Polystyrenes
Tissue engineering
6 Citations (Scopus)

Integration of adeno-associated virus-derived peptides into nonviral vectors to synergistically enhance cellular transfection

Kim, J. S., Kim, E., Oh, J. S. & Jang, J-H., 2013 Jul 8, In : Biomacromolecules. 14, 7, p. 2136-2145 10 p.

Research output: Contribution to journalArticle

Viruses
Peptides
Genes
Polyethyleneimine
Gene therapy
37 Citations (Scopus)

Intramuscular delivery of DNA releasing microspheres: Microsphere properties and transgene expression

Jang, J. H. & Shea, L. D., 2006 May 1, In : Journal of Controlled Release. 112, 1, p. 120-128 9 p.

Research output: Contribution to journalArticle

Transgenes
Microspheres
DNA
Polymers
Plasmids
3 Citations (Scopus)

Inverted Quasi-Spherical Droplets on Polydopamine–TiO2 Substrates for Enhancing Gene Delivery

Kim, S. H., Lee, M., Cho, M., Kim, I. S., Park, K. I., Lee, H. & Jang, J. H., 2017 Nov, In : Macromolecular Bioscience. 17, 11, 1700148.

Research output: Contribution to journalArticle

Genes
Substrates
Neural Stem Cells
Gene Transfer Techniques
Stem cells
20 Citations (Scopus)

Magnetically enhanced adeno-associated viral vector delivery for human neural stem cell infection

Kim, E., Oh, J. S., Ahn, I. S., Park, K. I. & Jang, J. H., 2011 Nov 1, In : Biomaterials. 32, 33, p. 8654-8662 9 p.

Research output: Contribution to journalArticle

Dependovirus
Neural Stem Cells
Stem cells
Viruses
Infection
102 Citations (Scopus)

Molecular evolution of adeno-associated virus for enhanced glial gene delivery

Koerber, J. T., Klimczak, R., Jang, J. H., Dalkara, D., Flannery, J. G. & Schaffer, D. V., 2009 Dec 1, In : Molecular Therapy. 17, 12, p. 2088-2095 8 p.

Research output: Contribution to journalArticle

Dependovirus
Molecular Evolution
Neuroglia
Astrocytes
Retina
1 Citation (Scopus)

Multifunctional Self-Adhesive Fibrous Layered Matrix (FiLM) for Tissue Glues and Therapeutic Carriers

Yoon, Y. E., Im, B. G., Kim, J. S. & Jang, J. H., 2017 Jan 9, In : Biomacromolecules. 18, 1, p. 127-140 14 p.

Research output: Contribution to journalArticle

Glues
Adhesives
Tissue
Scaffolds
Tissue Adhesives
2 Citations (Scopus)

Mutagenic Analysis of an Adeno-Associated Virus Variant Capable of Simultaneously Promoting Immune Resistance and Robust Gene Delivery

Kim, Y., Kim, E., Oh, S., Yoon, Y. E. & Jang, J. H., 2018 Jan, In : Human Gene Therapy. 29, 1, p. 25-41 17 p.

Research output: Contribution to journalArticle

Dependovirus
Neutralizing Antibodies
Genetic Therapy
Genes
Immunoglobulin G
101 Citations (Scopus)

Neurotrophin releasing single and multiple lumen nerve conduits

Yang, Y., De Laporte, L., Rives, C. B., Jang, J. H., Lin, W. C., Shull, K. R. & Shea, L. D., 2005 Jun 2, In : Journal of Controlled Release. 104, 3, p. 433-446 14 p.

Research output: Contribution to journalArticle

Nerve Growth Factors
Microspheres
Polymers
Nerve Growth Factor
Gases
51 Citations (Scopus)

Patterned PLG substrates for localized DNA delivery and directed neurite extension

Houchin-Ray, T., Swift, L. A., Jang, J. H. & Shea, L. D., 2007 Jun 1, In : Biomaterials. 28, 16, p. 2603-2611 9 p.

Research output: Contribution to journalArticle

Neurites
Neurons
DNA
Nerve Growth Factors
Accessories
6 Citations (Scopus)

PEGylation and HAylation via catechol: α-Amine-specific reaction at N-terminus of peptides and proteins

Song, I. T., Lee, M., Lee, H., Han, J., Jang, J. H., Lee, M. S., Koh, G. Y. & Lee, H., 2016 Oct 1, In : Acta Biomaterialia. 43, p. 50-60 11 p.

Research output: Contribution to journalArticle

Peptides
Amines
Proteins
Polyethylene glycols
Bioactivity
130 Citations (Scopus)

Plasmid delivery in vivo from porous tissue-engineering scaffolds: Transgene expression and cellular transfection

Jang, J. H., Rives, C. B. & Shea, L. D., 2005 Sep 1, In : Molecular Therapy. 12, 3, p. 475-483 9 p.

Research output: Contribution to journalArticle

Tissue Scaffolds
Tissue Engineering
Transgenes
Transfection
Plasmids
8 Citations (Scopus)

Polydopamine-Decorated Sticky, Water-Friendly, Biodegradable Polycaprolactone Cell Carriers

Kim, M., Kim, J. S., Lee, H. & Jang, J-H., 2016 May 1, In : Macromolecular Bioscience. 16, 5, p. 738-747 10 p.

Research output: Contribution to journalArticle

Polycaprolactone
Microspheres
Stem cells
Neural Stem Cells
Water
10 Citations (Scopus)

Polydopamine Inter-Fiber Networks: New Strategy for Producing Rigid, Sticky, 3D Fluffy Electrospun Fibrous Polycaprolactone Sponges

Choi, W., Lee, S., Kim, S. H. & Jang, J. H., 2016 Jun 1, In : Macromolecular Bioscience. p. 824-835 12 p.

Research output: Contribution to journalArticle

Polycaprolactone
Porifera
Tissue
Rigidity
Fibers
1 Citation (Scopus)

Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics

Cho, M., Jung, K., Kim, S. H., Kim, I. S., Kim, M., Shin, M., Lee, H., Park, K. I. & Jang, J. H., 2019 May 1, In : Gene Therapy. 26, 5, p. 135-150 16 p.

Research output: Contribution to journalArticle

Dependovirus
Neural Stem Cells
Interleukin-10
Safety
Virus Diseases
7 Citations (Scopus)

Salt-Induced Electrospun Patterned Bundled Fibers for Spatially Regulating Cellular Responses

Cho, M., Kim, S. H., Jin, G., Park, K. I. & Jang, J-H., 2016 Jun 1, In : ACS Applied Materials and Interfaces. 8, 21, p. 13320-13331 12 p.

Research output: Contribution to journalArticle

Salts
Fibers
Stem cells
Tissue Scaffolds
Recovery
18 Citations (Scopus)

Sliding Fibers: Slidable, Injectable, and Gel-like Electrospun Nanofibers as Versatile Cell Carriers

Lee, S., Yun, S., Park, K. I. & Jang, J-H., 2016 Mar 22, In : ACS Nano. 10, 3, p. 3282-3294 13 p.

Research output: Contribution to journalArticle

Nanofibers
sliding
Gels
gels
fibers
20 Citations (Scopus)

SpONGE: Spontaneous organization of numerous-layer generation by electrospray

Jin, G., Shin, M., Kim, S. H., Lee, H. & Jang, J-H., 2015 Jun 1, In : Angewandte Chemie - International Edition. 54, 26, p. 7587-7591 5 p.

Research output: Contribution to journalArticle

Biomolecules
Polymer solutions
Drug delivery
Salts
21 Citations (Scopus)

Sticky "delivering-from" strategies using viral vectors for efficient human neural stem cell infection by bioinspired catecholamines

Kim, E., Lee, S., Hong, S., Jin, G., Kim, M., Park, K. I., Lee, H. & Jang, J-H., 2014 Jun 11, In : ACS Applied Materials and Interfaces. 6, 11, p. 8288-8294 7 p.

Research output: Contribution to journalArticle

Stem cells
Catecholamines
Norepinephrine
Gene therapy
Fibroblast Growth Factor 2
19 Citations (Scopus)
absorbents
Drug delivery
delivery
Oils
drugs
76 Citations (Scopus)

Surface adsorption of DNA to tissue engineering scaffolds for efficient gene delivery

Jang, J. H., Bengali, Z., Houchin, T. L. & Shea, L. D., 2006 Apr 1, In : Journal of Biomedical Materials Research - Part A. 77, 1, p. 50-58 9 p.

Research output: Contribution to journalArticle

Tissue Scaffolds
Scaffolds (biology)
Tissue engineering
DNA
Genes
18 Citations (Scopus)

Surface immobilization of hexa-histidine-tagged adeno-associated viral vectors for localized gene delivery

Jang, J. H., Koerber, J. T., Gujraty, K., Bethi, S. R., Kane, R. S. & Schaffer, D. V., 2010 Nov 1, In : Gene Therapy. 17, 11, p. 1384-1389 6 p.

Research output: Contribution to journalArticle

Histidine
Immobilization
Genes
Genetic Therapy
Metals
29 Citations (Scopus)

Targeting protein and peptide therapeutics to the heart via tannic acid modification

Shin, M., Lee, H. A., Lee, M., Shin, Y., Song, J. J., Kang, S. W., Nam, D. H., Jeon, E. J., Cho, M., Do, M., Park, S., Lee, M. S., Jang, J. H., Cho, S. W., Kim, K. S. & Lee, H., 2018 May 1, In : Nature biomedical engineering. 2, 5, p. 304-317 14 p.

Research output: Contribution to journalArticle

Tannins
Protein Transport
Peptides
Blood vessels
Proteins
8 Citations (Scopus)

The promotion of human neural stem cells adhesion using bioinspired poly(norepinephrine) nanoscale coating

Park, M., Shin, M., Kim, E., Lee, S., Park, K. I., Lee, H. & Jang, J. H., 2014, In : Journal of Nanomaterials. 2014, 793052.

Research output: Contribution to journalArticle

Norepinephrine
Cell adhesion
Stem cells
Coatings
Biocompatible Materials
1 Citation (Scopus)

Transduction of striatum and cortex tissues by adeno-associated viral vectors produced by herpes simplex virus- and baculovirus-based methods

Zhang, H. S., Kim, E., Lee, S., Ahn, I. S. & Jang, J-H., 2012 Jan 1, In : Journal of Virological Methods. 179, 1, p. 276-280 5 p.

Research output: Contribution to journalArticle

Dependovirus
Baculoviridae
Simplexvirus
Transfection
Genes
3 Citations (Scopus)

Tubing-Electrospinning: A One-Step Process for Fabricating Fibrous Matrices with Spatial, Chemical, and Mechanical Gradients

Kim, J. S., Im, B. G., Jin, G. & Jang, J. H., 2016 Aug 31, In : ACS Applied Materials and Interfaces. 8, 34, p. 22721-22731 11 p.

Research output: Contribution to journalArticle

Electrospinning
Tubing
Tissue
Polymers
Tissue engineering
Conference article
1 Citation (Scopus)

Tissue engineering scaffolds for controlled protein and plasmid delivery

Shea, L. D., Whittlesey, K. J., Segura, T., Jang, J. & Yang, Y., 2002 Dec 1, In : Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1, 1 p.

Research output: Contribution to journalConference article

Tissue Scaffolds
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Plasmids
Conference contribution

Directed evolution of adeno-associated virus for enhanced gene delivery to pluripotent and adult neural stem cells

Kotterman, M. A., Asuri, P., Jang, J. H., Vazin, T. & Schaffer, D. V., 2013 Jan 1, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, 1 p. (Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dependovirus
Adult Stem Cells
Neural Stem Cells
Stem cells
Viruses

Liquid filled multilayered capsules for oral delivery

Kim, Y., Kim, J., Kim, Y. & Jang, J. H., 2019 Jan 1, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Capsules
Liquids
Oviparity
Sharks
Dependovirus
Review article
2 Citations (Scopus)

BiFACIAL (Bi omimetic F reestanding A nisotropic C atechol- i nterfaces with A symmetrically L ayered) Films as Versatile Extracellular Matrix Substitutes

Im, B. G., Do, M., Kim, Y., Cho, M. & Jang, J-H., 2018 Mar 7, In : ACS Applied Materials and Interfaces. 10, 9, p. 7602-7613 12 p.

Research output: Contribution to journalReview article

Biomimetics
Blood vessels
Chitosan
Skin
Tissue regeneration
27 Citations (Scopus)

Electrospun nanofibers as versatile interfaces for efficient gene delivery

Lee, S., Jin, G. & Jang, J. H., 2014 Dec 9, In : Journal of Biological Engineering. 8, 1, 30.

Research output: Contribution to journalReview article

Nanofibers
Genes
Cell Engineering
Technology
Military electronic countermeasures
81 Citations (Scopus)

Engineering biomaterial systems to enhance viral vector gene delivery

Jang, J. H., Schaffer, D. V. & Shea, L. D., 2011 Aug, In : Molecular Therapy. 19, 8, p. 1407-1415 9 p.

Research output: Contribution to journalReview article

Viral Genes
Biocompatible Materials
Tropism
Infectious Disease Medicine
Satellite Viruses