• 1425 Citations
  • 17 h-Index
20062019

Research output per year

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Research Output

  • 1425 Citations
  • 17 h-Index
  • 24 Article
  • 2 Short survey
  • 1 Comment/debate
  • 1 Editorial
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Article
2019

Epigenetic regulation of mammalian hedgehog signaling to the stroma determines the molecular subtype of bladder cancer

Kim, S., Kim, Y., Kong, J., Kim, E., Choi, J. H., Yuk, H. D., Lee, H., Kim, H. R., Lee, K. H., Kang, M., Roe, J. S., Moon, K. C., Kim, S., Ku, J. H. & Shin, K., 2019 Apr, In : eLife. 8, e43024.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Oncogenic KRAS sensitizes lung adenocarcinoma to GSK-J4–induced metabolic and oxidative stress

Hong, B. J., Park, W. Y., Kim, H. R., Moon, J. W., Lee, H. Y., Park, J. H., Kim, S. K., Oh, Y., Roe, J. S. & Kim, M. Y., 2019 Nov 15, In : Cancer Research. 79, 22, p. 5849-5859 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma

Banito, A., Li, X., Laporte, A. N., Roe, J. S., Sanchez-Vega, F., Huang, C. H., Dancsok, A. R., Hatzi, K., Chen, C. C., Tschaharganeh, D. F., Chandwani, R., Tasdemir, N., Jones, K. B., Capecchi, M. R., Vakoc, C. R., Schultz, N., Ladanyi, M., Nielsen, T. O. & Lowe, S. W., 2018 Mar 12, In : Cancer Cell. 33, 3, p. 527-541.e8

Research output: Contribution to journalArticle

30 Citations (Scopus)
2017

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

Roe, J. S., Hwang, C. I., Somerville, T. D. D., Milazzo, J. P., Lee, E. J., Da Silva, B., Maiorino, L., Tiriac, H., Young, C. M., Miyabayashi, K., Filippini, D., Creighton, B., Burkhart, R. A., Buscaglia, J. M., Kim, E. J., Grem, J. L., Lazenby, A. J., Grunkemeyer, J. A., Hollingsworth, M. A., Grandgenett, P. M. & 4 others, Egeblad, M., Park, Y., Tuveson, D. A. & Vakoc, C. R., 2017 Aug 24, In : Cell. 170, 5, p. 875-888.e20

Research output: Contribution to journalArticle

97 Citations (Scopus)

Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene

Fontanals-Cirera, B., Hasson, D., Vardabasso, C., Di Micco, R., Agrawal, P., Chowdhury, A., Gantz, M., de Pablos-Aragoneses, A., Morgenstern, A., Wu, P., Filipescu, D., Valle-Garcia, D., Darvishian, F., Roe, J. S., Davies, M. A., Vakoc, C. R., Hernando, E. & Bernstein, E., 2017 Nov 16, In : Molecular Cell. 68, 4, p. 731-744.e9

Research output: Contribution to journalArticle

22 Citations (Scopus)
2016

BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements

Bhagwat, A. S., Roe, J. S., Mok, B. Y. L., Hohmann, A. F., Shi, J. & Vakoc, C. R., 2016 Apr 19, In : Cell Reports. 15, 3, p. 519-530 12 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

BRD4 connects enhancer remodeling to senescence immune surveillance

Tasdemir, N., Banito, A., Roe, J. S., Alonso-Curbelo, D., Camiolo, M., Tschaharganeh, D. F., Huang, C. H., Aksoy, O., Bolden, J. E., Chen, C. C., Fennell, M., Thapar, V., Chicas, A., Vakoc, C. R. & Lowe, S. W., 2016 Jun, In : Cancer Discovery. 6, 6, p. 613-629 17 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition

Hohmann, A. F., Martin, L. J., Minder, J. L., Roe, J. S., Shi, J., Steurer, S., Bader, G., McConnell, D., Pearson, M., Gerstberger, T., Gottschamel, T., Thompson, D., Suzuki, Y., Koegl, M. & Vakoc, C. R., 2016 Sep 1, In : Nature Chemical Biology. 12, 9, p. 672-679 8 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

The essential transcriptional function of BRD4 in acute myeloid leukemia

Roe, J. S. & Vakoc, C. R., 2016 Jan 1, In : Cold Spring Harbor Symposia on Quantitative Biology. 81, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia

Roe, J. S., Mercan, F., Rivera, K., Pappin, D. J. & Vakoc, C. R., 2015 Jun 18, In : Molecular Cell. 58, 6, p. 1028-1039 12 p.

Research output: Contribution to journalArticle

154 Citations (Scopus)

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler

Shen, C., Ipsaro, J. J., Shi, J., Milazzo, J. P., Wang, E., Roe, J. S., Suzuki, Y., Pappin, D. J., Joshua-Tor, L. & Vakoc, C. R., 2015 Dec 17, In : Molecular Cell. 60, 6, p. 847-859 13 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancer

Kim, J. H., Lee, S. M., Lee, J. H., Chun, S., Kang, B. H., Kwak, S., Roe, J. S., Kim, T. W., Kim, H., Kim, W. H., Cho, E. J. & Youn, H. D., 2015 Jan 1, In : Oncotarget. 6, 23, p. 19528-19541 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

TGF-β/smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis

Yu, J. R., Tai, Y., Jin, Y., Hammell, M. C., Wilkinson, J. E., Roe, J. S., Vakoc, C. R. & Van Aelst, L., 2015 Jan 1, In : Genes and Development. 29, 3, p. 250-261 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer

Wang, E., Kawaoka, S., Roe, J. S., Shi, J., Hohmann, A. F., Xu, Y., Bhagwat, A. S., Suzuki, Y., Kinney, J. B. & Vakoc, C. R., 2015 Apr 28, In : eLife. 4, p. e06377

Research output: Contribution to journalArticle

11 Citations (Scopus)

The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer

Wang, E., Kawaoka, S., Roe, J. S., Shi, J., Hohmann, A. F., Xu, Y., Bhagwat, A. S., Kinney, J. B. & Vakoc, C. R., 2015 Apr 28, In : eLife. 2015, 4, e06377.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

Rathert, P., Roth, M., Neumann, T., Muerdter, F., Roe, J. S., Muhar, M., Deswal, S., Cerny-Reiterer, S., Peter, B., Jude, J., Hoffmann, T., Boryn, L. M., Axelsson, E., Schweifer, N., Tontsch-Grunt, U., Dow, L. E., Gianni, D., Pearson, M., Valent, P., Stark, A. & 3 others, Kraut, N., Vakoc, C. R. & Zuber, J., 2015 Sep 24, In : Nature. 525, 7570, p. 543-547 5 p.

Research output: Contribution to journalArticle

217 Citations (Scopus)
2013

P53 regulates glucose metabolism by miR-34a

Kim, H. R., Roe, J. S., Lee, J. E., Cho, E. J. & Youn, H. D., 2013 Jul 26, In : Biochemical and Biophysical Research Communications. 437, 2, p. 225-231 7 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Phosphorylation and ubiquitination-dependent degradation of CABIN1 releases p53 for transactivation upon genotoxic stress

Choi, S. Y., Jang, H., Roe, J. S., Kim, S. T., Cho, E. J. & Youn, H. D., 2013 Feb 1, In : Nucleic acids research. 41, 4, p. 2180-2190 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

Shi, J., Whyte, W. A., Zepeda-Mendoza, C. J., Milazzo, J. P., Shen, C., Roe, J. S., Minder, J. L., Mercan, F., Wang, E., Eckersley-Maslin, M. A., Campbell, A. E., Kawaoka, S., Shareef, S., Zhu, Z., Kendall, J., Muhar, M., Haslinger, C., Yu, M., Roeder, R. G., Wigler, M. H. & 5 others, Blobel, G. A., Zuber, J., Spector, D. L., Young, R. A. & Vakoc, C. R., 2013 Dec 15, In : Genes and Development. 27, 24, p. 2648-2662 15 p.

Research output: Contribution to journalArticle

200 Citations (Scopus)
2012

A p53-inducible microRNA-34a downregulates Ras signaling by targeting IMPDH

Kim, H. R., Roe, J. S., Lee, J. E., Hwang, I. Y., Cho, E. J. & Youn, H. D., 2012 Feb 24, In : Biochemical and Biophysical Research Communications. 418, 4, p. 682-688 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

pVHL-mediated transcriptional repression of c-Myc by recruitment of histone deacetylases

Hwang, I. Y., Roe, J. S., Seol, J. H., Kim, H. R., Cho, E. J. & Youn, H. D., 2012 Feb 1, In : Molecules and cells. 33, 2, p. 195-201 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2011

Phosphorylation of von Hippel-Lindau protein by checkpoint kinase 2 regulates p53 transactivation

Roe, J. S., Kim, H. R., Hwang, I. Y., Ha, N. C., Kim, S. T., Cho, E. J. & Youn, H. D., 2011 Nov 15, In : Cell Cycle. 10, 22, p. 3920-3928 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Von Hippel-Lindau protein promotes Skp2 destabilization on DNA damage

Roe, J. S., Kim, H. R., Hwang, I. Y., Cho, E. J. & Youn, H. D., 2011 Jul 14, In : Oncogene. 30, 28, p. 3127-3138 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2006

p53 Stabilization and Transactivation by a von Hippel-Lindau Protein

Roe, J. S., Kim, H., Lee, S. M., Kim, S. T., Cho, E. J. & Youn, H. D., 2006 May 5, In : Molecular Cell. 22, 3, p. 395-405 11 p.

Research output: Contribution to journalArticle

175 Citations (Scopus)