• 2236 Citations
  • 27 h-Index
19982020

Research output per year

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Research Output

  • 2236 Citations
  • 27 h-Index
  • 62 Article
  • 8 Review article
  • 2 Short survey
  • 1 Comment/debate
1998

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release

Bimston, D., Song, J., Winchester, D., Takayama, S., Reed, J. C. & Morimoto, R. I., 1998 Dec 1, In : EMBO Journal. 17, 23, p. 6871-6878 8 p.

Research output: Contribution to journalArticle

148 Citations (Scopus)
1999

The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity

Melville, M. W., Tan, S. L., Wambach, M., Song, J., Morimoto, R. I. & Katze, M. G., 1999 Feb 5, In : Journal of Biological Chemistry. 274, 6, p. 3797-3803 7 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)
2000

Analysis of molecular chaperone activities using in vitro and in vivo approaches.

Freeman, B. C., Michels, A., Song, J., Kampinga, H. H. & Morimoto, R. I., 2000, In : Methods in molecular biology (Clifton, N.J.). 99, p. 393-419 27 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)

Bag1 functions in vivo as a negative regulator of Hsp70 chaperone activity

Nollen, E. A. A., Brunsting, J. F., Song, J., Kampinga, H. H. & Morimoto, R. I., 2000 Feb, In : Molecular and cellular biology. 20, 3, p. 1083-1088 6 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
2001

Bag1-Hsp 70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth

Song, J., Takeda, M. & Morimoto, R. I., 2001 Mar 20, In : Nature Cell Biology. 3, 3, p. 276-282 7 p.

Research output: Contribution to journalArticle

216 Citations (Scopus)

Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

Thress, K., Song, J., Morimoto, R. I. & Kornbluth, S., 2001 Mar 1, In : EMBO Journal. 20, 5, p. 1033-1041 9 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)
2003

Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation

Oh, W. K. & Song, J., 2003 Aug 1, In : Molecules and cells. 16, 1, p. 84-91 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

HspBP1 is the negative regulator of the bovine progesterone receptor

Park, K. M. & Song, J. W., 2003 Sep 1, In : Asian-Australasian Journal of Animal Sciences. 16, 9, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper

Colón-Ramos, D. A., Irusta, P. M., Gan, E. C., Olson, M. R., Song, J., Morimoto, R. I., Elliott, R. M., Lombard, M., Hollingsworth, R., Hardwick, J. M., Smith, G. K. & Kornbluth, S., 2003 Oct 1, In : Molecular Biology of the Cell. 14, 10, p. 4162-4172 11 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
2004

Functional genomics approach using mice

Sung, Y. H., Song, J. & Lee, H. W., 2004 Jan 31, In : Journal of Biochemistry and Molecular Biology. 37, 1, p. 122-132 11 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)
2005

Extratelomeric functions of telomerase

Chung, H. K., Cheong, C., Song, J. & Lee, H. W., 2005 Mar 1, In : Current Molecular Medicine. 5, 2, p. 233-241 9 p.

Research output: Contribution to journalReview article

55 Citations (Scopus)

Generation of reversible Rb-knockdown mice

Yoon, S. C., Jae, E. L., Cheong, C., Young, H. S., Eun, Y. Y., Chan, B. P., Song, J., Sang, C. P. & Lee, H. W., 2005 Nov 1, In : Mechanisms of Ageing and Development. 126, 11, p. 1164-1169 6 p.

Research output: Contribution to journalArticle

Hematopoietic malignancies associated with increased Stat5 and Bcl-x L expressions in Ink4a/Arf-deficient mice

Young, H. S., Park, J., Choi, B., Kim, J., Cheong, C., Yoon, S. C., Eun, Y. Y., Lee, M., Jin, S. H., Sang, C. P., Han, T. H., Tae, J. K., Song, J., Rhee, K. & Lee, H. W., 2005 Jun 1, In : Mechanisms of Ageing and Development. 126, 6-7, p. 732-739 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2006

Hsp70 functions as a negative regulator of West Nile virus capsid protein through direct interaction

Oh, W. K. & Song, J., 2006 Sep 8, In : Biochemical and Biophysical Research Communications. 347, 4, p. 994-1000 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Jab1 as a mediator of nuclear export and cytoplasmic degradation of p53

Lee, E. W., Oh, W. & Song, J., 2006 Oct 1, In : Molecules and cells. 22, 2, p. 133-140 8 p.

Research output: Contribution to journalShort survey

30 Citations (Scopus)

Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2

Oh, W., Lee, E. W., Young, H. S., Yang, M. R., Ghim, J., Lee, H. W. & Song, J., 2006 Jun 23, In : Journal of Biological Chemistry. 281, 25, p. 17457-17465 9 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Jab1 mediates cytoplasmic localization and degradation of West Nile virus capsid protein

Oh, W., Yang, M. R., Lee, E. W., Park, K. M., Pyo, S., Yang, J. S., Lee, H. W. & Song, J., 2006 Oct 6, In : Journal of Biological Chemistry. 281, 40, p. 30166-30174 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Role of INK4a locus in normal eye development and cataract genesis

Cheong, C., Sung, Y. H., Lee, J., Choi, Y. S., Song, J., Kee, C. & Lee, H. W., 2006 Jul 1, In : Mechanisms of Ageing and Development. 127, 7, p. 633-638 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2008

Ikaros negatively regulates inducible nitric oxide synthase expression in macrophages: Involvement of Ikaros phosphorylation by casein kinase 2

Cho, S. J., Huh, J. E., Song, J., Rhee, D. K. & Pyo, S., 2008 Oct 1, In : Cellular and Molecular Life Sciences. 65, 20, p. 3290-3303 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

West Nile virus capsid protein induces p53-mediated apoptosis via the sequestration of HDM2 to the nucleolus

Yang, M. R., Lee, S. R., Oh, W., Lee, E. W., Yeh, J. Y., Nah, J. J., Joo, Y. S., Shin, J., Lee, H. W., Pyo, S. & Song, J., 2008 Jan 1, In : Cellular Microbiology. 10, 1, p. 165-176 12 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)
2009

Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

Lee, E. W., Lee, M. S., Camus, S., Ghim, J., Yang, M. R., Oh, W., Ha, N. C., Lane, D. P. & Song, J., 2009 Jul 22, In : EMBO Journal. 28, 14, p. 2100-2113 14 p.

Research output: Contribution to journalArticle

90 Citations (Scopus)

Jab1 has negative effects on p53-mediated genotoxic stresses

Lee, E. W., Lee, S. & Song, J., 2009 May, In : BMB reports. 42, 5, p. 299-303 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

PML-IV functions as a negative regulator of telomerase by interacting with TERT

Oh, W., Ghim, J., Lee, E. W., Yang, M. R., Kim, E. T., Ahn, J. H. & Song, J., 2009 Aug 1, In : Journal of cell science. 122, 15, p. 2613-2622 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2010

Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT

Oh, W., Lee, E. W., Lee, D., Yang, M. R., Ko, A., Yoon, C. H., Lee, H. W., Bae, Y. S., Choi, C. Y. & Song, J., 2010 Jul 1, In : Oncogene. 29, 28, p. 4101-4112 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

MKRN1 induces degradation of West Nile virus capsid protein by functioning as an E3 ligase

Ko, A., Lee, E. W., Yeh, J. Y., Yang, M. R., Oh, W., Moon, J. S. & Song, J., 2010 Jan, In : Journal of Virology. 84, 1, p. 426-436 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2012

Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF

Ko, A., Shin, J. Y., Seo, J., Lee, K. D., Lee, E. W., Lee, M. S., Lee, H. W., Choi, I. J., Jeong, J. S., Chun, K. H. & Song, J., 2012 Nov 7, In : Journal of the National Cancer Institute. 104, 21, p. 1660-1672 13 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
4 Citations (Scopus)

Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice

Devkota, S., Sung, Y. H., Choi, J. M., Lee, J., Ha, N. Y., Kim, H., Cho, B., Song, J. & Lee, H. W., 2012 Nov 1, In : International Journal of Biochemistry and Cell Biology. 44, 11, p. 1887-1896 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy

Ahn, Y. H., Yi, H., Shin, J. Y., Lee, K. D., Shin, S. P., Lee, S. J., Song, J. & Chun, K. H., 2012 Apr 1, In : Clinical and Experimental Metastasis. 29, 4, p. 359-369 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The roles of FADD in extrinsic apoptosis and necroptosis

Lee, E. W., Seo, J., Jeong, M., Lee, S. & Song, J., 2012, In : BMB reports. 45, 9, p. 496-508 13 p.

Research output: Contribution to journalReview article

73 Citations (Scopus)

Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis

Lee, E. W., Kim, J. H., Ahn, Y. H., Seo, J., Ko, A., Jeong, M., Kim, S. J., Ro, J. Y., Park, K. M., Lee, H. W., Park, E. J., Chun, K. H. & Song, J., 2012 Aug 15, In : Nature communications. 3, 978.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2013

Anti-cancer effect of a quinoxaline derivative GK13 as a transglutaminase 2 inhibitor

Lee, S. H., Kim, N., Kim, S. J., Song, J., Gong, Y. D. & Kim, S. Y., 2013 Aug 1, In : Journal of cancer research and clinical oncology. 139, 8, p. 1279-1294 16 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation

Hwang, Y. J., Lee, E. W., Song, J., Kim, H. R., Jun, Y. C. & Hwang, K. A., 2013 Nov 28, In : Scientific reports. 3, 3242.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response

Lee, M. S., Seo, J., Choi, D. Y., Lee, E. W., Ko, A., Ha, N. C., Bok Yoon, J., Lee, H. W., Pyo Kim, K. & Song, J., 2013 Apr 1, In : Cell Death and Differentiation. 20, 4, p. 620-629 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2014

Ablation of galectin-3 induces p27 KIP1-dependent premature senescence without oncogenic stress

Kim, S. J., Lee, H. W., Gu Kang, H., La, S. H., Choi, I. J., Ro, J. Y., Bresalier, R. S., Song, J. & Chun, K. H., 2014 Nov 1, In : Cell Death and Differentiation. 21, 11, p. 1769-1779 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells

Park, E. J., Choi, D. H., Kim, Y., Lee, E. W., Song, J., Cho, M. H., Kim, J. H. & Kim, S. W., 2014 Dec, In : Toxicology in Vitro. 28, 8, p. 1402-1412 11 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Oleanolic acid regulates NF-κB signaling by suppressing MafK expression in RAW 264.7 cells

Hwang, Y. J., Song, J., Kim, H. R. & Hwang, K. A., 2014, In : BMB reports. 47, 9, p. 524-529 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP

Ko, H. R., Kim, C. K., Lee, S. B., Song, J., Lee, K. H., Kim, K. K., Park, K. W., Cho, S. W. & Ahn, J. Y., 2014 Mar, In : Cell Death and Disease. 5, 3, e1131.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Suppression of PPARγ through MKRN1-mediated ubiquitination and degradation prevents adipocyte differentiation

Kim, J. H., Park, K. W., Lee, E. W., Jang, W. S., Seo, J., Shin, S., Hwang, K. A. & Song, J., 2014 Apr 1, In : Cell Death and Differentiation. 21, 4, p. 594-603 10 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

SWCNTs induced autophagic cell death in human bronchial epithelial cells

Park, E. J., Zahari, N. E. M., Lee, E. W., Song, J., Lee, J. H., Cho, M. H. & Kim, J. H., 2014 Apr 1, In : Toxicology in Vitro. 28, 3, p. 442-450 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2015

Camptothecin and topotecan inhibit adipocyte differentiation by inducing degradation of PPARγ

Kim, J. H., Jeong, M., Lee, S. S. & Song, J., 2015 Jul 13, In : Biochemical and Biophysical Research Communications. 463, 4, p. 1122-1128 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Galectin-3 activates PPARγ and supports white adipose tissue formation and high-fat diet-induced obesity

Baek, J. H., Kim, S. J., Kang, H. G., Lee, H. W., Kim, J. H., Hwang, K. A., Song, J. & Chun, K. H., 2015 Jan 1, In : Endocrinology. 156, 1, p. 147-156 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

Lee, M. S., Jeong, M. H., Lee, H. W., Han, H. J., Ko, A., Hewitt, S. M., Kim, J. H., Chun, K. H., Chung, J. Y., Lee, C., Cho, H. & Song, J., 2015 Jul 17, In : Nature communications. 6, 7769.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer

Lee, H. W., Kim, S. J., Choi, I. J., Song, J. & Chun, K. H., 2015 Aug 25, In : Clinical and Experimental Metastasis. 32, 6, p. 593-603 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in metabolism, immunity, and cancer

Kim, J. H., Song, J. & Park, K. W., 2015 Mar, In : Archives of pharmacal research. 38, 3, p. 302-312 11 p.

Research output: Contribution to journalReview article

35 Citations (Scopus)

USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics

Lee, E. W., Seong, D., Seo, J., Jeong, M., Lee, H. K. & Song, J., 2015 Sep 11, In : Cell Death and Differentiation. 22, 9, p. 1463-1476 14 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2016

Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer

Kim, S. J., Lee, H. W., Baek, J. H., Cho, Y. H., Kang, H. G., Jeong, J. S., Song, J., Park, H. S. & Chun, K. H., 2016 Jan 14, In : Oncogene. 35, 2, p. 251-260 10 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

CHIP controls necroptosis through ubiquitylation-and lysosome-dependent degradation of RIPK3

Seo, J., Lee, E. W., Sung, H., Seong, D., Dondelinger, Y., Shin, J., Jeong, M., Lee, H. K., Kim, J. H., Han, S. Y., Lee, C., Seong, J. K., Vandenabeele, P. & Song, J., 2016 Feb 25, In : Nature Cell Biology. 18, 3, p. 291-302 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC

Lee, J. S., Kang, J. H., Lee, S. H., Hong, D., Son, J., Hong, K. M., Song, J. & Kim, S. Y., 2016 Jan 1, In : Cell Death and Disease. 7, 12, e2511.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Dynamics of ARF regulation that control senescence and cancer

Ko, A., Han, S. Y. & Song, J., 2016, In : BMB reports. 49, 11, p. 598-606 9 p.

Research output: Contribution to journalReview article

12 Citations (Scopus)