• 2132 Citations
  • 26 h-Index
19982019

Research output per year

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Research Output

  • 2132 Citations
  • 26 h-Index
  • 61 Article
  • 8 Review article
  • 2 Short survey
  • 1 Comment/debate
Article

Ablation of galectin-3 induces p27 KIP1-dependent premature senescence without oncogenic stress

Kim, S. J., Lee, H. W., Gu Kang, H., La, S. H., Choi, I. J., Ro, J. Y., Bresalier, R. S., Song, J. & Chun, K. H., 2014 Nov 1, In : Cell Death and Differentiation. 21, 11, p. 1769-1779 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-α-Induced Apoptosis via Different Routes

Lee, S., Lee, J. Y., Lee, E. W., Park, S., Kang, D. H., Min, C., Lee, D. J., Kang, D., Song, J., Kwon, J. & Kang, S. W., 2019 Feb 19, In : Cell Reports. 26, 8, p. 2194-2211.e6

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF

Ko, A., Shin, J. Y., Seo, J., Lee, K. D., Lee, E. W., Lee, M. S., Lee, H. W., Choi, I. J., Jeong, J. S., Chun, K. H. & Song, J., 2012 Nov 7, In : Journal of the National Cancer Institute. 104, 21, p. 1660-1672 13 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer

Kim, S. J., Lee, H. W., Baek, J. H., Cho, Y. H., Kang, H. G., Jeong, J. S., Song, J., Park, H. S. & Chun, K. H., 2016 Jan 14, In : Oncogene. 35, 2, p. 251-260 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Anti-cancer effect of a quinoxaline derivative GK13 as a transglutaminase 2 inhibitor

Lee, S. H., Kim, N., Kim, S. J., Song, J., Gong, Y. D. & Kim, S. Y., 2013 Aug 1, In : Journal of cancer research and clinical oncology. 139, 8, p. 1279-1294 16 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release

Bimston, D., Song, J., Winchester, D., Takayama, S., Reed, J. C. & Morimoto, R. I., 1998 Dec 1, In : EMBO Journal. 17, 23, p. 6871-6878 8 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

Bag1 functions in vivo as a negative regulator of Hsp70 chaperone activity

Nollen, E. A. A., Brunsting, J. F., Song, J., Kampinga, H. H. & Morimoto, R. I., 2000 Feb 1, In : Molecular and Cellular Biology. 20, 3, p. 1083-1088 6 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Bag1-Hsp 70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth

Song, J., Takeda, M. & Morimoto, R. I., 2001 Mar 20, In : Nature Cell Biology. 3, 3, p. 276-282 7 p.

Research output: Contribution to journalArticle

216 Citations (Scopus)

Camptothecin and topotecan inhibit adipocyte differentiation by inducing degradation of PPARγ

Kim, J. H., Jeong, M., Lee, S. S. & Song, J., 2015 Jul 13, In : Biochemical and Biophysical Research Communications. 463, 4, p. 1122-1128 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

CHIP controls necroptosis through ubiquitylation-and lysosome-dependent degradation of RIPK3

Seo, J., Lee, E. W., Sung, H., Seong, D., Dondelinger, Y., Shin, J., Jeong, M., Lee, H. K., Kim, J. H., Han, S. Y., Lee, C., Seong, J. K., Vandenabeele, P. & Song, J., 2016 Feb 25, In : Nature Cell Biology. 18, 3, p. 291-302 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation

Oh, W. K. & Song, J., 2003 Aug 1, In : Molecules and Cells. 16, 1, p. 84-91 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ

Kim, J. H., Shin, S., Seo, J., Lee, E. W., Jeong, M., Lee, M. S., Han, H. J. & Song, J., 2017 Jan 6, In : Scientific reports. 7, 40023.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL

Yoon, M. K., Kim, B. Y., Lee, J. Y., Ha, J. H., Kim, S. A., Lee, D. H., Lee, M. S., Lee, M. K., Choi, J. S., Cho, J. H., Kim, J. H., Kim, S., Song, J., Park, S. G., Park, B. C., Bae, K. H., Choi, S. U. & Chi, S. W., 2018 Jan 1, In : Journal of Biological Chemistry. 293, 51, p. 19546-19558 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer

Shin, S., Kim, K., Kim, H. R., Ylaya, K., Do, S. I., Hewitt, S. M., Park, H. S., Roe, J. S., Chung, J. Y. & Song, J., 2019 Jan 1, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

Lee, E. W., Lee, M. S., Camus, S., Ghim, J., Yang, M. R., Oh, W., Ha, N. C., Lane, D. P. & Song, J., 2009 Jul 22, In : EMBO Journal. 28, 14, p. 2100-2113 14 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)
3 Citations (Scopus)

Dual loss of USP10 and p14ARF protein expression is associated with poor prognosis in patients with small intestinal adenocarcinoma

Song, J. S., Yi, J. M., Cho, H., Choi, C. H., Park, Y., Chung, E. J., Song, J., Chung, J. Y. & Hong, S. M., 2018 Oct 1, In : Tumor Biology. 40, 10

Research output: Contribution to journalArticle

2 Citations (Scopus)

Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC

Lee, J. S., Kang, J. H., Lee, S. H., Hong, D., Son, J., Hong, K. M., Song, J. & Kim, S. Y., 2016 Jan 1, In : Cell Death and Disease. 7, 12, e2511.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice

Devkota, S., Sung, Y. H., Choi, J. M., Lee, J., Ha, N. Y., Kim, H., Cho, B., Song, J. & Lee, H. W., 2012 Nov 1, In : International Journal of Biochemistry and Cell Biology. 44, 11, p. 1887-1896 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Galectin-3 activates PPARγ and supports white adipose tissue formation and high-fat diet-induced obesity

Baek, J. H., Kim, S. J., Kang, H. G., Lee, H. W., Kim, J. H., Hwang, K. A., Song, J. & Chun, K. H., 2015 Jan 1, In : Endocrinology. 156, 1, p. 147-156 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Generation of reversible Rb-knockdown mice

Yoon, S. C., Jae, E. L., Cheong, C., Young, H. S., Eun, Y. Y., Chan, B. P., Song, J., Sang, C. P. & Lee, H. W., 2005 Nov 1, In : Mechanisms of Ageing and Development. 126, 11, p. 1164-1169 6 p.

Research output: Contribution to journalArticle

Glatiramer acetate attenuates the activation of CD4 + T cells by modulating STAT1 and â'3 signaling in glia

Ahn, Y. H., Jeon, S. B., Chang, C. Y., Goh, E. A., Kim, S. S., Kim, H. J., Song, J. & Park, E. J., 2017 Jan 17, In : Scientific reports. 7, 40484.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT

Oh, W., Lee, E. W., Lee, D., Yang, M. R., Ko, A., Yoon, C. H., Lee, H. W., Bae, Y. S., Choi, C. Y. & Song, J., 2010 Jul 1, In : Oncogene. 29, 28, p. 4101-4112 12 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Hematopoietic malignancies associated with increased Stat5 and Bcl-x L expressions in Ink4a/Arf-deficient mice

Young, H. S., Park, J., Choi, B., Kim, J., Cheong, C., Yoon, S. C., Eun, Y. Y., Lee, M., Jin, S. H., Sang, C. P., Han, T. H., Tae, J. K., Song, J., Rhee, K. & Lee, H. W., 2005 Jun 1, In : Mechanisms of Ageing and Development. 126, 6-7, p. 732-739 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Hsp70 functions as a negative regulator of West Nile virus capsid protein through direct interaction

Oh, W. K. & Song, J., 2006 Sep 8, In : Biochemical and Biophysical Research Communications. 347, 4, p. 994-1000 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

HspBP1 is the negative regulator of the bovine progesterone receptor

Park, K. M. & Song, J., 2003 Sep 1, In : Asian-Australasian Journal of Animal Sciences. 16, 9, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

Ikaros negatively regulates inducible nitric oxide synthase expression in macrophages: Involvement of Ikaros phosphorylation by casein kinase 2

Cho, S. J., Huh, J. E., Song, J., Rhee, D. K. & Pyo, S., 2008 Oct 1, In : Cellular and Molecular Life Sciences. 65, 20, p. 3290-3303 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper

Colón-Ramos, D. A., Irusta, P. M., Gan, E. C., Olson, M. R., Song, J., Morimoto, R. I., Elliott, R. M., Lombard, M., Hollingsworth, R., Hardwick, J. M., Smith, G. K. & Kornbluth, S., 2003 Oct 1, In : Molecular Biology of the Cell. 14, 10, p. 4162-4172 11 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Jab1 has negative effects on p53-mediated genotoxic stresses

Lee, E. W., Lee, S. & Song, J., 2009 May, In : BMB reports. 42, 5, p. 299-303 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2

Oh, W., Lee, E. W., Young, H. S., Yang, M. R., Ghim, J., Lee, H. W. & Song, J., 2006 Jun 23, In : Journal of Biological Chemistry. 281, 25, p. 17457-17465 9 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Jab1 mediates cytoplasmic localization and degradation of West Nile virus capsid protein

Oh, W., Yang, M. R., Lee, E. W., Park, K. M., Pyo, S., Yang, J. S., Lee, H. W. & Song, J., 2006 Oct 6, In : Journal of Biological Chemistry. 281, 40, p. 30166-30174 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

K6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death

Seo, J., Lee, E. W., Shin, J., Seong, D., Nam, Y. W., Jeong, M., Lee, S. H., Lee, C. & Song, J., 2018 Sep 6, In : Oncogene. 37, 36, p. 4994-5006 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

Lee, M. S., Han, H. J., Han, S. Y., Kim, I. Y., Chae, S., Lee, C. S., Kim, S. E., Yoon, S. G., Park, J. W., Kim, J. H., Shin, S., Jeong, M., Ko, A., Lee, H. Y., Oh, K. J., Lee, Y-H., Bae, K. H., Koo, S. H., Kim, J. W., Seong, J. K. & 2 others, Hwang, D. & Song, J., 2018 Dec 1, In : Nature communications. 9, 1, 3404.

Research output: Contribution to journalArticle

11 Citations (Scopus)

MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation

Hwang, Y. J., Lee, E. W., Song, J., Kim, H. R., Jun, Y. C. & Hwang, K. A., 2013 Nov 28, In : Scientific reports. 3, 3242.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells

Park, E. J., Choi, D. H., Kim, Y., Lee, E. W., Song, J., Cho, M. H., Kim, J. H. & Kim, S. W., 2014 Dec, In : Toxicology in Vitro. 28, 8, p. 1402-1412 11 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

MKRN1 induces degradation of West Nile virus capsid protein by functioning as an E3 ligase

Ko, A., Lee, E. W., Yeh, J. Y., Yang, M. R., Oh, W., Moon, J. S. & Song, J., 2010 Jan 1, In : Journal of Virology. 84, 1, p. 426-436 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Molecular chaperone HSP90 is necessary to prevent cellular senescence via lysosomal degradation of p14ARF

Han, S. Y., Ko, A., Kitano, H., Choi, C. H., Lee, M. S., Seo, J., Fukuoka, J., Kim, S. Y., Hewitt, S. M., Chung, J. Y. & Song, J., 2017 Jan 15, In : Cancer Research. 77, 2, p. 343-354 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

New role of E3 ubiquitin ligase in the regulation of necroptosis

Seo, J., Lee, E. W. & Song, J., 2016 May 1, In : BMB reports. 49, 5, p. 247-248 2 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Oleanolic acid regulates NF-κB signaling by suppressing MafK expression in RAW 264.7 cells

Hwang, Y. J., Song, J., Kim, H. R. & Hwang, K. A., 2014 Jan 1, In : BMB reports. 47, 9, p. 524-529 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF

Ko, A., Han, S. Y., Choi, C. H., Cho, H., Lee, M. S., Kim, S. Y., Song, J. S., Hong, K. M., Lee, H. W., Hewitt, S. M., Chung, J. Y. & Song, J., 2018 Jun 1, In : Cell Death and Differentiation. 25, 6, p. 1050-1062 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP

Ko, H. R., Kim, C. K., Lee, S. B., Song, J., Lee, K. H., Kim, K. K., Park, K. W., Cho, S. W. & Ahn, J. Y., 2014 Jan 1, In : Cell Death and Disease. 5, 3, e1131.

Research output: Contribution to journalArticle

22 Citations (Scopus)

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

Lee, M. S., Jeong, M. H., Lee, H. W., Han, H. J., Ko, A., Hewitt, S. M., Kim, J. H., Chun, K. H., Chung, J. Y., Lee, C., Cho, H. & Song, J., 2015 Jul 17, In : Nature communications. 6, 7769.

Research output: Contribution to journalArticle

60 Citations (Scopus)

PML-IV functions as a negative regulator of telomerase by interacting with TERT

Oh, W., Ghim, J., Lee, E. W., Yang, M. R., Kim, E. T., Ahn, J. H. & Song, J., 2009 Aug 1, In : Journal of cell science. 122, 15, p. 2613-2622 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

Park, T. J., Park, J. H., Lee, G. S., Lee, J. Y., Shin, J. H., Kim, M. W., Kim, Y. S., Kim, J. Y., Oh, K. J., Han, B. S., Kim, W. K., Ahn, Y., Moon, J. H., Song, J., Bae, K. H., Kim, D. H., Lee, E. W. & Lee, S. C., 2019 Nov 1, In : Cell Death and Disease. 10, 11, 835.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

Thress, K., Song, J., Morimoto, R. I. & Kornbluth, S., 2001 Mar 1, In : EMBO Journal. 20, 5, p. 1033-1041 9 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Role of INK4a locus in normal eye development and cataract genesis

Cheong, C., Sung, Y. H., Lee, J., Choi, Y. S., Song, J., Kee, C. & Lee, H. W., 2006 Jul 1, In : Mechanisms of Ageing and Development. 127, 7, p. 633-638 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury

Martens, S., Jeong, M., Tonnus, W., Feldmann, F., Hofmans, S., Goossens, V., Takahashi, N., Bräsen, J. H., Lee, E. W., Van der Veken, P., Joossens, J., Augustyns, K., Fulda, S., Linkermann, A., Song, J. & Vandenabeele, P., 2017 Jun 29, In : Cell death & disease. 8, 6, p. e2904

Research output: Contribution to journalArticle

28 Citations (Scopus)

Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response

Lee, M. S., Seo, J., Choi, D. Y., Lee, E. W., Ko, A., Ha, N. C., Bok Yoon, J., Lee, H. W., Pyo Kim, K. & Song, J., 2013 Apr 1, In : Cell Death and Differentiation. 20, 4, p. 620-629 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy

Ahn, Y. H., Yi, H., Shin, J. Y., Lee, K. D., Shin, S. P., Lee, S. J., Song, J. & Chun, K. H., 2012 Apr 1, In : Clinical and Experimental Metastasis. 29, 4, p. 359-369 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Suppression of PPARγ through MKRN1-mediated ubiquitination and degradation prevents adipocyte differentiation

Kim, J. H., Park, K. W., Lee, E. W., Jang, W. S., Seo, J., Shin, S., Hwang, K. A. & Song, J., 2014 Apr 1, In : Cell Death and Differentiation. 21, 4, p. 594-603 10 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)