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2020

O-GlcNAcylation on LATS2 disrupts the Hippo pathway by inhibiting its activity

Kima, E., Kima, E., Kang, J. G., Kang, M. J., Park, J. H., Kim, Y. J., Kim, Y. J., Kweon, T. H., Kweon, T. H., Lee, H. W., Jho, E. H., Jho, E. H., Lee, Y. H., Lee, Y. H., Kim, S. I., Yi, E. C., Yi, E. C., Park, H. W., Yang, W. H., Yang, W. H. & 3 others, Cho, J. W., Cho, J. W. & Cho, J. W., 2020 Jun 23, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 25, p. 14259-14269 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

Kim, S. R., Lee, S. G., Kim, S. H., Kim, J. H., Choi, E., Cho, W., Rim, J. H., Hwang, I., Lee, C. J., Lee, M., Oh, C. M., Jeon, J. Y., Gee, H. Y., Kim, J. H., Lee, B. W., Kang, E. S., Cha, B. S., Lee, M. S., Yu, J. W., Cho, J. W. & 2 others, Kim, J. S. & Lee, Y. H., 2020 Dec 1, In : Nature communications. 11, 1, 2127.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019

Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP+-induced neuronal death

Jung, S., Chung, Y., Lee, Y., Lee, Y., Cho, J. W., Shin, E. J., Kim, H. C. & Oh, Y. J., 2019 Dec 1, In : Cell Death Discovery. 5, 1, 130.

Research output: Contribution to journalArticle

Open Access

Liver disease–associated keratin 8 and 18 mutations modulate keratin acetylation and methylation

Jang, K. H., Yoon, H. N., Lee, J., Yi, H., Park, S. Y., Lee, S. Y., Lim, Y., Lee, H. J., Cho, J. W., Paik, Y. K., Hancock, W. S. & Ku, N. O., 2019 Aug 1, In : FASEB Journal. 33, 8, p. 9030-9043 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Refinements of LC-MS/MS Spectral Counting Statistics Improve Quantification of Low Abundance Proteins

Lee, H. Y., Kim, E. G., Jung, H. R., Jung, J. W., Kim, H. B., Cho, J. W., Kim, K. M. & Yi, E. C., 2019 Dec 1, In : Scientific reports. 9, 1, 13653.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Senescent T cells predict the development of hyperglycemia in humans

Lee, Y. H., Kim, S. R., Han, D. H., Yu, H. T., Han, Y. D., Kim, J. H., Kim, S. H., Lee, C. J., Min, B. H., Kim, D. H., Kim, K. H., Cho, J. W., Lee, W. W., Shin, E. C. & Park, S., 2019 Jan 1, In : Diabetes. 68, 1, p. 156-162 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Sodium-glucose cotransporter 2 inhibitors regulate ketone body metabolism via inter-organ crosstalk

Kim, J. H., Lee, M., Kim, S. H., Kim, S. R., Lee, B. W., Kang, E. S., Cha, B. S., Cho, J. W. & Lee, Y. H., 2019 Apr, In : Diabetes, Obesity and Metabolism. 21, 4, p. 801-811 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Trifunctional Fluorogenic Probes for Fluorescence Imaging and Isolation of Glycosidases in Cells

Hyun, J. Y., Park, S. H., Park, C. W., Kim, H. B., Cho, J. W. & Shin, I., 2019 Jun 21, In : Organic Letters. 21, 12, p. 4439-4442 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Dysregulated autophagy contributes to caspase-dependent neuronal apoptosis

Chung, Y., Lee, J., Jung, S., Lee, Y., Cho, J. W. & Oh, Y. J., 2018 Dec 1, In : Cell Death and Disease. 9, 12, 1189.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR

Noh, S. H., Gee, H. Y., Kim, Y., Piao, H., Kim, J., Kang, C. M., Lee, G., Mook-Jung, I., Lee, Y., Cho, J. W. & Lee, M. G., 2018 Oct 3, In : Autophagy. 14, 10, p. 1761-1778 18 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Structural basis for arginine glycosylation of host substrates by bacterial effector proteins

Park, J. B., Kim, Y. H., Yoo, Y., Kim, J., Jun, S. H., Cho, J. W., El Qaidi, S., Walpole, S., Monaco, S., García-García, A. A., Wu, M., Hays, M. P., Hurtado-Guerrero, R., Angulo, J., Hardwidge, P. R., Shin, J. S. & Cho, H. S., 2018 Dec 1, In : Nature communications. 9, 1, 4283.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2016

Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation

Seo, H. G., Kim, H. B., Kang, M. J., Ryum, J. H., Yi, E. C. & Cho, J. W., 2016 Oct 7, In : Scientific reports. 6, 34614.

Research output: Contribution to journalArticle

17 Citations (Scopus)

O-GlcNAcylation of orphan nuclear receptor estrogen-related receptorγ promotes hepatic gluconeogenesis

Misra, J., Kim, D. K., Jung, Y. S., Kim, H. B., Kim, Y. H., Yoo, E. K., Kim, B. G., Kim, S., Lee, I. K., Harris, R. A., Kim, J. S., Lee, C. H., Cho, J. W. & Choi, H. S., 2016 Oct 1, In : Diabetes. 65, 10, p. 2835-2848 14 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

O-linked N-acetylglucosamine transferase promotes cervical cancer tumorigenesis through human papillomaviruses E6 and E7 oncogenes

Kim, M., Kim, Y. S., Kim, H., Kang, M. Y., Park, J., Lee, D. H., Roh, G. S., Kim, H. J., Kang, S. S., Cho, G. J., Park, J. K., Cho, J. W., Shin, J. K. & Choi, W. S., 2016, In : Oncotarget. 7, 28, p. 44596-44607 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells

Ra, E. A., Lee, T. A., Won Kim, S., Park, A., Choi, H. J., Jang, I., Kang, S., Hee Cheon, J., Cho, J. W., Eun Lee, J., Lee, S. & Park, B., 2016 May 24, In : Nature communications. 7, 11726.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2015

CCCTC-binding factor controls the homeostatic maintenance and migration of Langerhans cells

Kim, T. G., Kim, M., Lee, J. J., Kim, S. H., Je, J. H., Lee, Y., Song, M. J., Choi, Y., Chung, Y. W., Park, C. G., Cho, J. W., Lee, M. G., Lee, Y. S. & Kim, H. P., 2015 Sep 1, In : Journal of Allergy and Clinical Immunology. 136, 3, p. 713-724 12 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Mitochondrial ATP synthase activity is impaired by suppressed O-GlcNAcylation in Alzheimer's disease

Cha, M. Y., Cho, H. J., Kim, C., Jung, Y. O., Kang, M. J., Murray, M. E., Hong, H. S., Choi, Y. J., Choi, H., Kim, D. K., Choi, H., Kim, J., Dickson, D. W., Song, H. K., Cho, J. W., Yi, E. C., Kim, J., Jin, S. M. & Mook-Jung, I., 2015, In : Human molecular genetics. 24, 22, p. 6492-6504 13 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster

Park, S., Lee, Y., Pak, J. W., Kim, H., Choi, H., Kim, J. W., Roth, J. & Cho, J. W., 2015 Aug 25, In : Cellular and Molecular Life Sciences. 72, 16, p. 3173-3183 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

O-GlcNAcylation of eIF2α regulates the phospho-eIF2α-mediated ER stress response

Jang, I., Kim, H. B., Seo, H., Kim, J. Y., Choi, H., Yoo, J. S., Kim, J. W. & Cho, J. W., 2015 Aug 1, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 8, p. 1860-1869 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
10 Citations (Scopus)
2014

ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase

Park, S., Jang, I., Zuber, C., Lee, Y., Cho, J. W., Matsuo, I., Ito, Y. & Roth, J., 2014 Aug, In : Histochemistry and cell biology. 142, 2, p. 153-169 17 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Genetic ablation and short-duration inhibition of lipoxygenase results in increased macroautophagy

Jang, I., Park, S., Cho, J. W., Yigitkanli, K., van Leyen, K. & Roth, J., 2014 Feb 15, In : Experimental Cell Research. 321, 2, p. 276-287 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Inhibition of mTOR affects protein stability of OGT

Park, S., Pak, J., Jang, I. & Cho, J. W., 2014 Oct 17, In : Biochemical and Biophysical Research Communications. 453, 2, p. 208-212 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2013

Chemical approaches to study O-GlcNAcylation

Banerjee, P. S., Hart, G. W. & Won Cho, J., 2013 Apr 29, In : Chemical Society reviews. 42, 10, p. 4345-4357 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Large protein complexes retained in the ER are dislocated by non-COPII vesicles and degraded by selective autophagy

Le Fourn, V., Park, S., Jang, I., Gaplovska-Kysela, K., Guhl, B., Lee, Y., Cho, J. W., Zuber, C. & Roth, J., 2013 Jun, In : Cellular and Molecular Life Sciences. 70, 11, p. 1985-2002 18 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment

Kim, C., Nam, D. W., Park, S. Y., Song, H., Hong, H. S., Boo, J. H., Jung, E. S., Kim, Y., Baek, J. Y., Kim, K. S., Cho, J. W. & Mook-Jung, I., 2013 Jan, In : Neurobiology of Aging. 34, 1, p. 275-285 11 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

The Third ACGG-DB Meeting Report: Towards an international collaborative infrastructure for glycobioinformatics

Aoki-Kinoshita, K. F., Sawaki, H., An, H. J., Cho, J. W., Hsu, D., Kato, M., Kawano, S., Kawasaki, T., Khoo, K. H., Kim, J., Kim, J. D., Li, X., Lütteke, T., Okuda, S., Packer, N. H., Paulson, J. C., Raman, R., Ranzinger, R., Shen, H., Shikanai, T. & 7 others, Yamada, I., Yang, P., Yamaguchi, Y., Ying, W., Yoo, J. S., Zhang, Y. & Narimatsu, H., 2013 Feb, In : Glycobiology. 23, 2, p. 144-146 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2012

A role for O-GlcNAcylation in setting circadian clock speed

Kim, E. Y., Jeong, E. H., Park, S., Jeong, H. J., Edery, I. & Cho, J. W., 2012 Mar 1, In : Genes and Development. 26, 5, p. 490-502 13 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

O-GlcNAc modification of PPARγ reduces its transcriptional activity

Ji, S., Park, S. Y., Roth, J., Kim, H. S. & Cho, J. W., 2012 Jan 27, In : Biochemical and Biophysical Research Communications. 417, 4, p. 1158-1163 6 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2011

A novel zinc-carboxypeptidase SURO-1 regulates cuticle formation and body morphogenesis in Caenorhabditis elegans

Kim, T. H., Kim, Y. J., Cho, J. W. & Shim, J., 2011 Jan 3, In : FEBS Letters. 585, 1, p. 121-127 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling

Cha, B., Kim, W., Kim, Y. K., Hwang, B. N., Park, S. Y., Yoon, J. W., Park, W. S., Cho, J. W., Bedford, M. T. & Jho, E. H., 2011 May 19, In : Oncogene. 30, 20, p. 2379-2389 11 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

O-GlcNAcylation of tubulin inhibits its polymerization

Ji, S., Kang, J. G., Park, S. Y., Lee, J., Oh, Y. J. & Cho, J. W., 2011 Mar, In : Amino Acids. 40, 3, p. 809-818 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Protein O-GlcNAcylation regulates Drosophila growth through the insulin signaling pathway

Park, S., Park, S. H., Baek, J. Y., Jy, Y. J., Kim, K. S., Roth, J., Cho, J. W. & Choe, K. M., 2011 Oct, In : Cellular and Molecular Life Sciences. 68, 20, p. 3377-3384 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

TGF-β-stimulated aberrant expression of class III β-tubulin via the ERK signaling pathway in cultured retinal pigment epithelial cells

Chung, E. J., Chun, J. N., Jung, S. A., Cho, J. W. & Lee, J. H., 2011 Nov 18, In : Biochemical and Biophysical Research Communications. 415, 2, p. 367-372 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2010

Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction

Kim, S. H., Kim, S. H., Choi, M., Lee, Y., Kim, Y. O., Ahn, D. S., Kim, Y. H., Kang, E. S., Lee, E. J., Jung, M., Cho, J. W., Williams, D. R. & Lee, H. C., 2010 Sep 1, In : Cardiovascular Research. 87, 4, p. 713-722 10 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

O-GlcNAcylation regulates hyperglycemia-induced GPX1 activation

Yang, W. H., Park, S. Y., Ji, S., Kang, J. G., Kim, J. E., Song, H., Mook-Jung, I., Choe, K. M. & Cho, J. W., 2010 Jan 1, In : Biochemical and Biophysical Research Communications. 391, 1, p. 756-761 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway

Hur, K. Y., Kim, S. H., Choi, M. A., Williams, D. R., Lee, Y. H., Kang, S. W., Yadav, U. C. S., Srivastava, S. K., Jung, M., Cho, J. W., Kim, S. G., Kang, E. S., Lee, E. J. & Lee, H. C., 2010 Jul, In : Atherosclerosis. 211, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition

Park, S. Y., Kim, H. S., Kim, N. H., Ji, S., Cha, S. Y., Kang, J. G., Ota, I., Shimada, K., Konishi, N., Nam, H. W., Hong, S. W., Yang, W. H., Roth, J., Yook, J. I. & Cho, J. W., 2010 Nov 17, In : EMBO Journal. 29, 22, p. 3787-3796 10 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Tyrosylprotein sulfotransferase regulates collagen secretion in Caenorhabditis elegans.

Kim, T. H., Kim, D. H., Nam, H. W., Park, S. Y., Shim, J. & Cho, J. W., 2010 Apr, In : Molecules and cells. 29, 4, p. 413-418 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2009

Chemoenzymatic syntheses of carbasugar analogues of nucleoside diphosphate sugars: UDP-carba-Gal, UDP-carba-GlcNAc, UDP-carba-Glc, and GDP-carba-Man

Seo, K. C., Kwon, Y. G., Kim, D. H., Jang, I. S., Cho, J. W. & Chung, S. K., 2009, In : Chemical Communications. 13, p. 1733-1735 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Excessive O-GlcNAcylation of proteins suppresses spontaneous cardiogenesis in ES cells

Kim, H. S., Park, S. Y., Choi, Y. R., Kang, J. G., Joo, H. J., Moon, W. K. & Cho, J. W., 2009 Aug 6, In : FEBS Letters. 583, 15, p. 2474-2478 5 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

O-GlcNAc protein modification in cancer cells increases in response to glucose deprivation through glycogen degradation

Kang, J. G., Park, S. Y., Ji, S., Jang, I., Park, S., Kim, H. S., Kim, S. M., Yook, J. I., Park, Y. I., Roth, J. & Cho, J. W., 2009 Dec 11, In : Journal of Biological Chemistry. 284, 50, p. 34777-34784 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2008

NFκB activation is associated with its O-GlcNAcylation state under hyperglycemic conditions

Won, H. Y., Sang, Y. P., Hyung, W. N., Do, H. K., Jeong, G. K., Eun, S. K., Yu, S. K., Hyun, C. L., Kwan, S. K. & Cho, J. W., 2008 Nov 11, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 45, p. 17345-17350 6 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)
2007

Activation of MEK-ERK by heregulin-β1 promotes the development of cardiomyocytes derived from ES cells

Kim, H. S., Cho, J. W., Hidaka, K. & Morisaki, T., 2007 Sep 28, In : Biochemical and Biophysical Research Communications. 361, 3, p. 732-738 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Cloning, characterization and expression of a gene encoding dihydroxyacetone synthase in Mycobacterium sp. strain JC1 DSM 3803

Seo, J. G., Park, S. W., Park, H., Kim, S. Y., Ro, Y. T., Kim, E., Cho, J. W. & Kim, Y. M., 2007 Dec, In : Microbiology. 153, 12, p. 4174-4182 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2006

Heat shock protein 60 modified with O-linked N-acetylglucosamine is involved in pancreatic β-cell death under hyperglycemic conditions

Kim, H. S., Kim, E. M., Lee, J., Yang, W. H., Park, T. Y., Kim, Y. M. & Cho, J. W., 2006 Apr 17, In : FEBS Letters. 580, 9, p. 2311-2316 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability

Yang, W. H., Kim, J. E., Nam, H. W., Ju, J. W., Kim, H. S., Kim, Y. S. & Cho, J. W., 2006 Oct, In : Nature Cell Biology. 8, 10, p. 1074-1083 10 p.

Research output: Contribution to journalArticle

281 Citations (Scopus)
2005

Activation of c-Jun N-terminal kinase is required for neurite outgrowth of dopaminergic neuronal cells

Eom, D. S., Choi, W. S., Ji, S., Cho, J. W. & Oh, Y. J., 2005 May 31, In : NeuroReport. 16, 8, p. 823-828 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

De novo formation of basal bodies in Naegleria gruberi: Regulation by phosphorylation

Kim, H. K., Kang, J. G., Yumura, S., Walsh, C. J., Jin, W. C. & Lee, J., 2005 Jun, In : Journal of Cell Biology. 169, 5, p. 719-724 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Efficient prefractionation of low-abundance proteins in human plasma and construction of a two-dimensional map

Cho, S. Y., Lee, E. Y., Lee, J. S., Kim, H. Y., Park, J. M., Kwon, M. S., Park, Y. K., Lee, H. J., Kang, M. J., Kim, J. Y., Yoo, J. S., Park, S. J., Cho, J. W., Kim, H. S. & Paik, Y. K., 2005 Aug, In : Proteomics. 5, 13, p. 3386-3396 11 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)