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1990 …2019
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Research Output 1990 2019

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Article
2019
4 Citations (Scopus)

A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer

Park, J., Cho, Y. H., Shin, W. J., Lee, S. K., Lee, J. H., Kim, T., Cha, P. H., Yang, J. S., Cho, J., Min, D. S., Han, G., Lee, H. Y. & Choi, K-Y., 2019 Dec 1, In : Scientific reports. 9, 1, 648.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Catenins
Wnt Signaling Pathway

A therapeutic strategy for chemotherapy-resistant gastric cancer via destabilization of both β-catenin and ras

Ryu, W. J., Lee, J. E., Cho, Y. H., Lee, G., Seo, M. K., Lee, S. K., Hwang, J. H., Min, D. S., Noh, S. H., Paik, S., Kim, S., Cheong, J. H. & Choi, K-Y., 2019 Apr 1, In : Cancers. 11, 4, 496.

Research output: Contribution to journalArticle

Open Access
Catenins
Stomach Neoplasms
Drug Therapy
oxaliplatin
Heterografts

CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Choi, S., Kim, H. Y., Cha, P. H., Seo, S. H., Lee, C., Choi, Y., Shin, W., Heo, Y., Han, G., Lee, W. T. & Choi, K-Y., 2019 Jan 1, In : Life Science Alliance. 2, 2, e201800254.

Research output: Contribution to journalArticle

Open Access
growth plate
Growth Plate
Bone Development
senescence
Fingers

WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer

Ro, E. J., Cho, Y. H., Jeong, W. J., Park, J. C., Min, D. S. & Choi, K-Y., 2019 Jul 30, In : Cell Communication and Signaling. 17, 1, 88.

Research output: Contribution to journalArticle

Open Access
Neoplastic Stem Cells
Stem cells
Colorectal Neoplasms
Chemical activation
Proteins
3 Citations (Scopus)

WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation

Jeong, W. J., Park, J. C., Kim, W. S., Ro, E. J., Jeon, S. H., Lee, S. K., Park, Y. N., Min, D. S. & Choi, K-Y., 2019 Dec 1, In : Nature communications. 10, 1, 295.

Research output: Contribution to journalArticle

suppressors
Tumors
Carrier Proteins
tumors
degradation
2018

A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab

Lee, S. K., Cho, Y. H., Cha, P. H., Yoon, J. S., Ro, E. J., Jeong, W. J., Park, J., Kim, H., Il Kim, T., Min, D. S., Han, G. & Choi, K-Y., 2018 Nov 1, In : Experimental and Molecular Medicine. 50, 11, 153.

Research output: Contribution to journalArticle

Catenins
Epidermal Growth Factor Receptor
Colorectal Neoplasms
Mutation
Molecules
2 Citations (Scopus)

Discovery of a small-molecule inhibitor of Dvl–CXXC5 interaction by computational approaches

Ma, S., Choi, J., Jin, X., Kim, H. Y., Yun, J. H., Lee, W., Choi, K-Y. & No, K. T., 2018 May 1, In : Journal of Computer-Aided Molecular Design. 32, 5, p. 643-655 13 p.

Research output: Contribution to journalArticle

PDZ Domains
inhibitors
Proteins
Molecules
Fingers
2 Citations (Scopus)

Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signaling

Shin, W., Lee, S. K., Hwang, J. H., Park, J. C., Cho, Y. H., Ro, E. J., Song, Y., Seo, H. R. & Choi, K-Y., 2018 Jun 1, In : Experimental and Molecular Medicine. 50, 6, 71.

Research output: Contribution to journalArticle

Catenins
Colorectal Neoplasms
Cells
Molecules
Degradation
5 Citations (Scopus)

Transcutaneous implantation of valproic acid-encapsulated dissolving microneedles induces hair regrowth

Fakhraei Lahiji, S., Seo, S. H., Kim, S., Dangol, M., Shim, J., Li, C. G., Ma, Y., Lee, C., Kang, G., Yang, H., Choi, K-Y. & Jung, H., 2018 Jun 1, In : Biomaterials. 167, p. 69-79 11 p.

Research output: Contribution to journalArticle

Valproic Acid
Hair Follicle
Re-Epithelialization
Acids
Catenins
3 Citations (Scopus)

β-Catenin-RAS interaction serves as a molecular switch for RAS degradation via GSK3β

Lee, S. K., Jeong, W. J., Cho, Y. H., Cha, P. H., Yoon, J. S., Ro, E. J., Choi, S., Oh, J. M., Heo, Y., Kim, H., Min, D. S., Han, G., Lee, W. T. & Choi, K-Y., 2018 Dec 1, In : EMBO Reports. 19, 12, e46060.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Catenins
Switches
Degradation
Phosphorylation
2017
1 Citation (Scopus)

Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5

Lee, I., Choi, S., Yun, J. H., Seo, S. H., Choi, S., Choi, K-Y. & Lee, W. T., 2017 Apr 8, In : Biochemical and Biophysical Research Communications. 485, 3, p. 584-590 7 p.

Research output: Contribution to journalArticle

PDZ Domains
Crystal structure
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Essential Drugs
7 Citations (Scopus)

MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting β-catenin and ATP-binding cassette, subfamily G, member 2

Kang, D. W., Yang, E. S., Noh, Y. N., Hwang, W. C., Jo, S. Y., Suh, Y. A., Park, W. S., Choi, K-Y. & Min, D. S., 2017 Apr 1, In : Journal of Pathology. 241, 5, p. 614-625 12 p.

Research output: Contribution to journalArticle

Catenins
Cytotoxins
MicroRNAs
Helicobacter pylori
Adenosine Triphosphate
3 Citations (Scopus)

Phospholipase D1 acts through Akt/TopBP1 and RB1 to regulate the E2F1-dependent apoptotic program in cancer cells

Kang, D. W., Lee, S. W., Hwang, W. C., Lee, B. H., Choi, Y. S., Suh, Y. A., Choi, K-Y. & Min, D. S., 2017 Jan 1, In : Cancer Research. 77, 1, p. 142-152 11 p.

Research output: Contribution to journalArticle

Neoplasms
Catenins
Colonic Neoplasms
Colorectal Neoplasms
phospholipase D1
6 Citations (Scopus)

Phospholipase D1 inhibition linked to upregulation of ICAT blocks colorectal cancer growth hyperactivated by Wnt/β-catenin and PI3K/Akt signaling

Kang, D. W., Lee, B. H., Suh, Y. A., Choi, Y. S., Jang, S. J., Kim, Y. M., Choi, K-Y. & Min, D. S., 2017 Dec 1, In : Clinical Cancer Research. 23, 23, p. 7340-7350 11 p.

Research output: Contribution to journalArticle

Catenins
Phosphatidylinositol 3-Kinases
Colorectal Neoplasms
Up-Regulation
Growth
1 Citation (Scopus)

Stabilization of Sur8 via PKCα/δ degradation promotes transformation and migration of colorectal cancer cells

Lee, K. H., Jeong, W. J., Cha, P. H., Lee, S. K., Min, D. S. & Choi, K-Y., 2017 Jan 1, In : Oncotarget. 8, 70, p. 115596-115608 13 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Fibroblast Growth Factor 2
Mitogen-Activated Protein Kinases
Phosphorylation
Polyubiquitin
15 Citations (Scopus)

Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis

Lee, S. H., Seo, S. H., Lee, D. H., Pi, L. Q., Lee, W. S. & Choi, K-Y., 2017 Nov 1, In : Journal of Investigative Dermatology. 137, 11, p. 2260-2269 10 p.

Research output: Contribution to journalArticle

Catenins
Hair Follicle
Wnt Signaling Pathway
Hair
Peptides
2016
7 Citations (Scopus)

CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation

Kim, M. Y., Kim, H. Y., Hong, J., Kim, D., Lee, H., Cheong, E., Lee, Y., Roth, J., Kim, D. G., Min, D. S. & Choi, K-Y., 2016 Mar 1, In : GLIA. 64, 3, p. 350-362 13 p.

Research output: Contribution to journalArticle

Oligodendroglia
Myelin Sheath
Corpus Callosum
Genes
Gene Expression
4 Citations (Scopus)

Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies

Choi, J., Ma, S. L., Kim, H. Y., Yun, J. H., Heo, J. N., Lee, W. T., Choi, K-Y. & No, K. T., 2016 Jan 1, In : Bioorganic and Medicinal Chemistry. 24, 15, p. 3259-3266 8 p.

Research output: Contribution to journalArticle

PDZ Domains
Screening
Binders
Molecules
Wnt Signaling Pathway
16 Citations (Scopus)

KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer

Cho, Y. H., Cha, P. H., Kaduwal, S., Park, J. C., Lee, S. K., Yoon, J. S., Shin, W., Kim, H., Ro, E. J., Koo, K. H., Park, K. S., Han, G. & Choi, K-Y., 2016 Jan 1, In : Oncotarget. 7, 49, p. 81727-81740 14 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Colorectal Neoplasms
Carcinogenesis
Neoplasm Metastasis
5 Citations (Scopus)

Polygonum aviculare L. And its active compounds, quercitrin hydrate, caffeic acid, and rutin, activate the Wnt/β-catenin pathway and induce cutaneous wound healing

Seo, S. H., Lee, S. H., Cha, P. H., Kim, M. Y., Min, D. S. & Choi, K-Y., 2016 May 1, In : Phytotherapy Research. 30, 5, p. 848-854 7 p.

Research output: Contribution to journalArticle

Polygonum
Catenins
Rutin
Wnt Signaling Pathway
Wound Healing
4 Citations (Scopus)

Rebamipide attenuates Helicobacter pylori CagA-induced self-renewal capacity via modulation of β-catenin signaling axis in gastric cancer-initiating cells

Kang, D. W., Noh, Y. N., Hwang, W. C., Choi, K-Y. & Min, D. S., 2016 Aug 1, In : Biochemical Pharmacology. 113, p. 36-44 9 p.

Research output: Contribution to journalArticle

Catenins
Helicobacter pylori
Stomach Neoplasms
Modulation
MicroRNAs
9 Citations (Scopus)

Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development

Park, J. C., Jeong, W. J., Kim, M. Y., Min, D. S. & Choi, K-Y., 2016 Jan 1, In : Journal of cell science. 129, 15, p. 2997-3007 11 p.

Research output: Contribution to journalArticle

Neural Stem Cells
Tretinoin
Cell Differentiation
Brain
Vitamin A
1 Citation (Scopus)
Catenins
Colorectal Neoplasms
Adenomatous Polyposis Coli
Therapeutics
Mutation
17 Citations (Scopus)

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

Cha, P. H., Cho, Y. H., Lee, S. K., Lee, J., Jeong, W. J., Moon, B. S., Yun, J. H., Yang, J. S., Choi, S., Yoon, J., Kim, H. Y., Kim, M. Y., Kaduwal, S., Lee, W. T., Min, D. S., Kim, H., Han, G. & Choi, K-Y., 2016 Aug 1, In : Nature Chemical Biology. 12, 8, p. 593-600 8 p.

Research output: Contribution to journalArticle

Catenins
Colorectal Neoplasms
Neoplasms
Mutation
Wnt Signaling Pathway
11 Citations (Scopus)

Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy

Kim, H. Y., Choi, S., Yoon, J. H., Lim, H. J., Lee, H., Choi, J., Ro, E. J., Heo, J. N., Lee, W. T., No, K. T. & Choi, K-Y., 2016 Apr 1, In : EMBO Molecular Medicine. 8, 4, p. 375-387 13 p.

Research output: Contribution to journalArticle

Drug Interactions
Catenins
Osteoporosis
Anabolic Agents
Bone and Bones
2 Citations (Scopus)

STAT3 potentiates SIAH-1 mediated proteasomal degradation of β-Catenin in human embryonic kidney cells

Shin, M., Yi, E. H., Kim, B. H., Shin, J. C., Park, J. Y., Cho, C. H., Park, J. W., Choi, K-Y. & Ye, S. K., 2016 Nov 1, In : Molecules and cells. 39, 11, p. 821-826 6 p.

Research output: Contribution to journalArticle

Catenins
Kidney
Wnt Signaling Pathway
Ubiquitin-Protein Ligases
Ubiquitin
4 Citations (Scopus)

Sur8 mediates tumorigenesis and metastasis in colorectal cancer

Lee, Y. M., Kaduwal, S., Lee, K. H., Park, J. C., Jeong, W. J. & Choi, K-Y., 2016 Jul 29, In : Experimental & molecular medicine. 48, 7, p. e249

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Liver
Colorectal Neoplasms
Carcinogenesis
Cells
2015
24 Citations (Scopus)

CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation

Kim, H. Y., Yoon, J. Y., Yun, J. H., Cho, K. W., Lee, S. H., Rhee, Y., Jung, H., Lim, H. J., Lee, H., Choi, J., Heo, J. N., Lee, W. T., No, K. T., Min, D. & Choi, K-Y., 2015 Jun 1, In : Cell Death and Differentiation. 22, 6, p. 912-920 9 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Osteoblasts
Fingers
Proteins
13 Citations (Scopus)

Euodia sutchuenensis Dode extract stimulates osteoblast differentiation via Wnt/β-catenin pathway activation

Hwang, J. H., Cha, P. H., Han, G., Bach, T. T. H., Min, D. S. I. & Choi, K-Y., 2015 Jan 1, In : Experimental & molecular medicine. 47, p. e152

Research output: Contribution to journalArticle

Evodia
Catenins
Wnt Signaling Pathway
Osteoblasts
Chemical activation
9 Citations (Scopus)

K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

Koo, K. H., Jeong, W. J., Cho, Y. H., Park, J. C., Min, D. S. & Choi, K-Y., 2015 Jan 1, In : Oncotarget. 6, 25, p. 21328-21340 13 p.

Research output: Contribution to journalArticle

Estrogens
Carcinogenesis
Endometrial Neoplasms
ras Proteins
Heterografts
17 Citations (Scopus)

NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction

Kim, K. H., Kim, D., Park, J. Y., Jung, H. J., Cho, Y. H., Kim, H. K., Han, J., Choi, K-Y. & Kwon, H. J., 2015 May 1, In : Journal of Molecular Medicine. 93, 5, p. 499-509 11 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Angiogenesis Inhibitors
Signal Transduction
Neoplasms
(1S,2S)-2-(2-(N-((3-benzimidazol-2-yl)propyl)-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride
7 Citations (Scopus)

N-nicotinoyl tyramine, a novel niacinamide derivative, inhibits melanogenesis by suppressing MITF gene expression

Kim, B., Lee, S. H., Choi, K-Y. & Kim, H. S., 2015 Jul 1, In : European Journal of Pharmacology. 764, p. 1-8 8 p.

Research output: Contribution to journalArticle

Microphthalmia-Associated Transcription Factor
Niacinamide
Monophenol Monooxygenase
Bleaching Agents
Gene Expression
1 Citation (Scopus)

Phospholipase D2 promotes degradation of hypoxia-inducible factor-1α independent of lipase activity

Park, M. H., Bae, S. S., Choi, K-Y. & Min, D. S., 2015 Jan 1, In : Experimental and Molecular Medicine. 47, 11, e196.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Lipase
Degradation
Proteins
Hydroxylation
16 Citations (Scopus)

Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

Kaduwal, S., Jeong, W. J., Park, J. C., Lee, K. H., Lee, Y. M., Jeon, S. H., Lim, Y., Min, D. S. & Choi, K-Y., 2015 Jan 1, In : Oncotarget. 6, 32, p. 33091-33105 15 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Extracellular Signal-Regulated MAP Kinases
Cell Movement
Neoplasm Metastasis
Melanoma
20 Citations (Scopus)

Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells

Kang, D. W. O., Choi, C. Y. E., Cho, Y. H., Tian, H., Di Paolo, G., Choi, K-Y. & Min, D. S. I., 2015 Jul 27, In : The Journal of experimental medicine. 212, 8, p. 1219-1237 19 p.

Research output: Contribution to journalArticle

Catenins
Carcinogenesis
Neoplasms
MicroRNAs
Colonic Neoplasms
21 Citations (Scopus)

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

Lee, S. H., Kim, M. Y., Kim, H. Y., Lee, Y. M., Kim, H., Nam, K. A., Roh, M., Min, D. S., Chung, K. Y. & Choi, K-Y., 2015 Jan 1, In : Journal of Experimental Medicine. 212, 7, p. 1061-1080 20 p.

Research output: Contribution to journalArticle

Catenins
Wound Healing
Carrier Proteins
Skin
Collagen
1 Citation (Scopus)
Hypoxia-Inducible Factor 1
Endocytosis
Epidermal Growth Factor Receptor
Phospholipase D
Hypoxia-Inducible Factor-Proline Dioxygenases
2014
18 Citations (Scopus)

CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation

Kim, H. Y., Yang, D. H., Shin, S. W., Kim, M. Y., Yoon, J. H., Kim, S., Park, H. C., Kang, D. W., Min, D., Hur, M. W. & Choi, K-Y., 2014 Jan 1, In : FASEB Journal. 28, 2, p. 615-626 12 p.

Research output: Contribution to journalArticle

Endothelial cells
Cell Differentiation
Bone
Endothelial Cells
Bone and Bones
15 Citations (Scopus)

Hovenia dulcis Thunb extract and its ingredient methyl vanillate Activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice

Cha, P. H., Shin, W., Zahoor, M., Kim, H. Y., Min, D. S. & Choi, K-Y., 2014 Jan 22, In : PloS one. 9, 1, e85546.

Research output: Contribution to journalArticle

Hovenia dulcis
Catenins
Wnt Signaling Pathway
Osteoblasts
Bone
7 Citations (Scopus)
Catenins
Obese Mice
Oximes
High Fat Diet
Bone and Bones
15 Citations (Scopus)

Indirubin-3'-oxime reverses bone loss in ovariectomized and hindlimb-unloaded mice via activation of the Wnt/β-catenin signaling

Zahoor, M., Cha, P. H., Min, D. S. & Choi, K-Y., 2014 Jan 1, In : Journal of Bone and Mineral Research. 29, 5, p. 1196-1205 10 p.

Research output: Contribution to journalArticle

Catenins
Oximes
Hindlimb
Bone and Bones
Osteoporosis
7 Citations (Scopus)

Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells

Hwang, W. C., Kim, M. K., Song, J. H., Choi, K-Y. & Min, D. S., 2014 Jan 1, In : Experimental and Molecular Medicine. 46, 12, e124.

Research output: Contribution to journalArticle

Autophagy
Colorectal Neoplasms
Cells
Phospholipase D
AMP-Activated Protein Kinases
9 Citations (Scopus)

Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability

Park, M. H., Choi, K-Y., Jung, Y. & Min, D. S., 2014 Jan 1, In : Oncotarget. 5, 23, p. 11857-11872 16 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor-Proline Dioxygenases
Hypoxia-Inducible Factor 1
Proteins
Prolyl Hydroxylases
Multiprotein Complexes
19 Citations (Scopus)

Phospholipase D-mediated autophagic regulation is a potential target for cancer therapy

Jang, Y. H., Choi, K-Y. & Min, D. S., 2014 Apr 1, In : Cell Death and Differentiation. 21, 4, p. 533-546 14 p.

Research output: Contribution to journalArticle

Phospholipase D
Autophagy
Neoplasms
Adenosine Monophosphate
Protein Kinases
71 Citations (Scopus)

Role of oncogenic K-Ras in cancer stem cell activation by aberrant wnt/β-catenin signaling

Moon, B. S., Jeong, W. J., Park, J., Kim, T. I., Min, D. S. & Choi, K-Y., 2014 Feb 1, In : Journal of the National Cancer Institute. 106, 2

Research output: Contribution to journalArticle

Catenins
Neoplastic Stem Cells
Mutation
Adenomatous Polyposis Coli
Carcinogenesis
18 Citations (Scopus)

The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity

Choi, O. M., Cho, Y. H., Choi, S., Lee, S. H., Seo, S. H., Kim, H. Y., Han, G., Min, D. S., Park, T. & Choi, K-Y., 2014 Jan 1, In : International Journal of Obesity. 38, 8, p. 1044-1052 9 p.

Research output: Contribution to journalArticle

Catenins
Oximes
Adipocytes
Obesity
High Fat Diet
2013
6 Citations (Scopus)

Caffeic acid phenethyl ester downregulates phospholipase D1 via direct binding and inhibition of NFκB transactivation

Park, M. H., Kang, D. W., Jung, Y., Choi, K-Y. & Min, D. S., 2013 Dec 6, In : Biochemical and Biophysical Research Communications. 442, 1-2, p. 1-7 7 p.

Research output: Contribution to journalArticle

Transcriptional Activation
Down-Regulation
Phospholipase D
Propolis
Phosphatidic Acids
6 Citations (Scopus)

Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents

Song, D., Yang, J. S., Kim, S. J., Kim, B. K., Park, S. K., Won, M., Kim, H. M., Choi, K-Y., Lee, K., Lee, K. & Han, G., 2013 Feb 1, In : Bioorganic and Medicinal Chemistry. 21, 3, p. 788-794 7 p.

Research output: Contribution to journalArticle

Ammonium Compounds
Antineoplastic Agents
Assays
Salts
Phosphatidylinositol 3-Kinase
11 Citations (Scopus)

House dust mite allergen der f 2 induces interleukin-13 expression by activating the PI3K/Akt pathway

Ro, E. J., Cha, P. H., Kim, H. Y., Cho, Y. H., Park, J., Han, J. S. & Choi, K-Y., 2013 May 1, In : Immunologic Research. 56, 1, p. 181-188 8 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Dermatophagoides Antigens
Interleukin-13
NF-kappa B
Asthma
22 Citations (Scopus)

Phospholipase d1 has a pivotal role in interleukin-1βdriven chronic autoimmune arthritis through regulation of NF-κB, hypoxia-inducible factor 1α, and foxo3a

Kang, D. W., Park, M. K., Oh, H. J., Lee, D. G., Park, S. H., Cho, M. L., Choi, K-Y. & Min, D. S., 2013 Jul 1, In : Molecular and Cellular Biology. 33, 14, p. 2760-2772 13 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Interleukins
Arthritis
Interleukin-1
Rheumatoid Arthritis