• 3852 Citations
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1990 …2020

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Article

Activation of protein kinase C by 1-beta-D-arabinofuranosylcytosine conjugates of phospholipid.

Lee, K. H., Jung, Y. J., Hong, C. I., Cho, M. H., Bai, D. H., Kim, S. H., Choi, K. Y., Yu, J. H. & Kim, C. M., 2004 Jan, In : International journal of oncology. 24, 1, p. 193-199 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Akt is involved in the inhibition of cell proliferation by EGF

Soung, H. J., Jeong, W. J., Cho, J. Y., Lee, K. H. & Choi, K. Y., 2007 Aug 31, In : Experimental and Molecular Medicine. 39, 4, p. 491-498 8 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

A mixed micellar formulation for the transdermal delivery of an Indirubin analog

Seo, S. H., Kim, E., Joo, Y., Lee, J., Oh, K. T., Hwang, S. J. & Choi, K. Y., 2020 Feb, In : Pharmaceutics. 12, 2, 175.

Research output: Contribution to journalArticle

Open Access

A mutant KRAS-induced factor REG4 promotes cancer stem cell properties via Wnt/β-catenin signaling

Hwang, J. H., Yoon, J., Cho, Y. H., Cha, P. H., Park, J. C. & Choi, K. Y., 2020 May 15, In : International Journal of Cancer. 146, 10, p. 2877-2890 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling

Yao, T. W., Kim, W. S., Yu, D. M. T., Sharbeen, G., McCaughan, G. W., Choi, K. Y., Xia, P. & Gorrell, M. D., 2011 Jul 1, In : Molecular Cancer Research. 9, 7, p. 948-959 12 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

APC inhibits ERK pathway activation and cellular proliferation induce by RAS

Park, K. S., Jeon, S. H., Kim, S. E., Bahk, Y. Y., Holmer, S. L., Williams, B. O., Chung, K. C., Surh, Y. J. & Choi, K. Y., 2006 Mar 1, In : Journal of cell science. 119, 5, p. 819-827 9 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

A positively charged residue bound in the minor groove does not alter the bending of a DNA duplex

Glasfeld, A., Schumacher, M. A., Choi, K. Y., Zalkin, H. & Brennan, R. G., 1996 Dec 25, In : Journal of the American Chemical Society. 118, 51, p. 13073-13074 2 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer

Park, J., Cho, Y. H., Shin, W. J., Lee, S. K., Lee, J. H., Kim, T., Cha, P. H., Yang, J. S., Cho, J., Min, D. S., Han, G., Lee, H. Y. & Choi, K. Y., 2019 Dec 1, In : Scientific reports. 9, 1, 648.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab

Lee, S. K., Cho, Y. H., Cha, P. H., Yoon, J. S., Ro, E. J., Jeong, W. J., Park, J., Kim, H., Il Kim, T., Min, D. S., Han, G. & Choi, K. Y., 2018 Nov 1, In : Experimental and Molecular Medicine. 50, 11, 153.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Association of a RUNX2 promoter polymorphism with bone mineral density in postmenopausal Korean women

Lee, H. J., Koh, J. M., Hwang, J. Y., Choi, K. Y., Lee, S. H., Park, E. K., Kim, T. H., Han, B. G., Kim, G. S., Kim, S. Y. & Lee, J. Y., 2009 Jun 1, In : Calcified Tissue International. 84, 6, p. 439-445 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

A therapeutic strategy for chemotherapy-resistant gastric cancer via destabilization of both β-catenin and ras

Ryu, W. J., Lee, J. E., Cho, Y. H., Lee, G., Seo, M. K., Lee, S. K., Hwang, J. H., Min, D. S., Noh, S. H., Paik, S., Kim, S., Cheong, J. H. & Choi, K. Y., 2019 Apr, In : Cancers. 11, 4, 496.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Axin inhibits extracellular signal-regulated kinase pathway by ras degradation via β-catenin

Soung, H. J., Yoon, J. Y., Park, Y. N., Jeong, W. J., Kim, S., Jho, E. H., Surh, Y. J. & Choi, K. Y., 2007 May 11, In : Journal of Biological Chemistry. 282, 19, p. 14482-14492 11 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
14 Citations (Scopus)

Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway

Moon, B. S., Yoon, J. Y., Kim, M. Y., Lee, S. H., Choi, T. & Choi, K. Y., 2009 Feb 28, In : Experimental and Molecular Medicine. 41, 2, p. 116-125 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Both ERK and Wnt/β-catenin pathways are involved in Wnt3a-induced proliferation

Yun, M. S., Kim, S. E., Jeon, S. H., Lee, J. S. & Choi, K. Y., 2005 Jan 15, In : Journal of cell science. 118, 2, p. 313-322 10 p.

Research output: Contribution to journalArticle

151 Citations (Scopus)

Caffeic acid phenethyl ester downregulates phospholipase D1 via direct binding and inhibition of NFκB transactivation

Park, M. H., Kang, D. W., Jung, Y., Choi, K. Y. & Min, D. S., 2013 Dec 6, In : Biochemical and Biophysical Research Communications. 442, 1-2, p. 1-7 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Characterization of Fus3 localization: Active Fus3 localizes in complexes of varying size and specific activity

Choi, K. Y., Kranz, J. E., Mahanty, S. K., Park, K. S. & Elion, E. A., 1999 May, In : Molecular Biology of the Cell. 10, 5, p. 1553-1568 16 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Chromosomal end fusion resulting from telomere erosion increases susceptibility to radiation via multinucleation: Effect of p53

Ju, Y. J., Park, J. E., Juhn, K. M., Jeong, J., Yun, M., Park, M. J., Park, G. H., Choi, K. Y., Cho, M. H., Wong, K. K., Park, W. B. & Lee, K. H., 2006 Oct 1, In : International journal of oncology. 29, 4, p. 753-763 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Controlled transcriptional regulation in eukaryotes by a novel transcription factor derived from Escherichia coli purine repressor

Yeon, E. H., Noh, J. Y., Kim, J. M., Lee, M. Y., Yoon, S., Park, S. K., Choi, K. Y. & Kim, K. S., 2004 Jun 25, In : Biochemical and Biophysical Research Communications. 319, 2, p. 334-341 8 p.

Research output: Contribution to journalArticle

Co-treatment with retinyl retinoate and a PPARα agonist reduces retinoid dermatitis

Kim, B., Kim, J. E., Kim, H., Lee, J. D., Choi, K. Y. & Lee, S. H., 2012 Jun 1, In : International Journal of Dermatology. 51, 6, p. 733-741 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Crystallization and preliminary X-ray analysis of an Escherichia coli purine repressor-hypoxanthine-DNA complex

Schumacher, M. A., Choi, K. Y., Zalkin, H. & Brennan, R. G., 1994 Sep 22, In : Journal of Molecular Biology. 242, 3, p. 302-305 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Crystallization and preliminary X-ray studies on the co-repressor binding domain of the Escherichia coli purine repressor

Schumacher, M. A., Choi, K. Y., Zalkin, H. & Brennan, R. G., 1992 Jun 20, In : Journal of Molecular Biology. 225, 4, p. 1131-1133 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Crystal structure of LacI member, PurR, bound to DNA: Minor groove binding by α helices

Schumacher, M. A., Choi, K. Y., Zalkin, H. & Brennan, R. G., 1994 Jan 1, In : Science. 266, 5186, p. 763-770 8 p.

Research output: Contribution to journalArticle

321 Citations (Scopus)

Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5

Lee, I., Choi, S., Yun, J. H., Seo, S. H., Choi, S., Choi, K. Y. & Lee, W., 2017 Apr 8, In : Biochemical and Biophysical Research Communications. 485, 3, p. 584-590 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation

Kim, H. Y., Yoon, J. Y., Yun, J. H., Cho, K. W., Lee, S. H., Rhee, Y. M., Jung, H. S., Lim, H. J., Lee, H., Choi, J., Heo, J. N., Lee, W., No, K. T., Min, D. & Choi, K. Y., 2015 Jun 1, In : Cell Death and Differentiation. 22, 6, p. 912-920 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

CXXC5 is a transcriptional activator of Flk-1 and mediates bone morphogenic protein-induced endothelial cell differentiation and vessel formation

Kim, H. Y., Yang, D. H., Shin, S. W., Kim, M. Y., Yoon, J. H., Kim, S., Park, H. C., Kang, D. W., Min, D., Hur, M. W. & Choi, K. Y., 2014 Feb, In : FASEB Journal. 28, 2, p. 615-626 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Choi, S., Kim, H. Y., Cha, P. H., Seo, S. H., Lee, C., Choi, Y., Shin, W., Heo, Y., Han, G., Lee, W. & Choi, K. Y., 2019, In : Life Science Alliance. 2, 2, e201800254.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation

Kim, M. Y., Kim, H. Y., Hong, J., Kim, D., Lee, H., Cheong, E., Lee, Y., Roth, J., Kim, D. G., Min, D. S. & Choi, K. Y., 2016 Mar 1, In : Glia. 64, 3, p. 350-362 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents

Song, D., Yang, J. S., Kim, S. J., Kim, B. K., Park, S. K., Won, M., Kim, H. M., Choi, K. Y., Lee, K., Lee, K. & Han, G., 2013 Feb 1, In : Bioorganic and Medicinal Chemistry. 21, 3, p. 788-794 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer

Ryu, W. J., Lee, J. D., Park, J. C., Cha, P. H., Cho, Y. H., Kim, J. Y., Sohn, J. H., Paik, S. & Choi, K. Y., 2020 May 1, In : Experimental and Molecular Medicine. 52, 5, p. 832-842 11 p.

Research output: Contribution to journalArticle

Open Access

Differential modulation of zinc-stimulated p21Cip/WAF1 and cyclin D1 induction by inhibition of PI3 kinase in HT-29 colorectal cancer cells

Oh, S. Y., Park, K. S., Kim, J. A. & Choi, K. Y., 2002 Mar 31, In : Experimental and Molecular Medicine. 34, 1, p. 27-31 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Differential regulation of MAP kinase cascade in human colorectal tumorigenesis

Park, K. S., Kim, N. G., Kim, J. J., Kim, H., Ahn, Y. H. & Choi, K. Y., 1999 Jan 1, In : British journal of cancer. 81, 7, p. 1116-1121 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Differential transmission of G1 cell cycle arrest and mating signals by saccharomyces cerevisiae Ste5 mutants in the pheromone pathway

Choi, Y. J., Kim, S. H., Park, K. S. & Choi, K. Y., 1999 Dec 1, In : Biochemistry and Cell Biology. 77, 5, p. 459-468 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Discovery of a small-molecule inhibitor of Dvl–CXXC5 interaction by computational approaches

Ma, S., Choi, J., Jin, X., Kim, H. Y., Yun, J. H., Lee, W., Choi, K. Y. & No, K. T., 2018 May 1, In : Journal of Computer-Aided Molecular Design. 32, 5, p. 643-655 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Drosophila extracellular signal-regulated kinase involves the insulin-mediated proliferation of schneider cells

Kwon, H. B., Kim, S. H., Kim, S. E., Jang, I. H., Ahn, Y., Lee, W. J. & Choi, K. Y., 2002 Apr 26, In : Journal of Biological Chemistry. 277, 17, p. 14853-14858 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells

Kim, S. E., Cho, J. Y., Kim, K. S., Lee, S. J., Lee, K. H. & Choi, K. Y., 2004 Nov 1, In : Cellular Signalling. 16, 11, p. 1309-1317 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

EGF receptor is involved in WNT3a-mediated proliferation and motility of NIH3T3 cells via ERK pathway activation

Kim, S. E. & Choi, K. Y., 2007 Jul 1, In : Cellular Signalling. 19, 7, p. 1554-1564 11 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

ERK activation is involved in tooth development via FGF10 signaling

Cho, K. W., Cai, J., Kim, H. Y., Hosoya, A., Ohshima, H., Choi, K. Y. & Jung, H. S., 2009 Dec 1, In : Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 312, 8, p. 901-911 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Euodia sutchuenensis Dode extract stimulates osteoblast differentiation via Wnt/β-catenin pathway activation

Hwang, J. H., Cha, P. H., Han, G., Bach, T. T. H., Min, D. S. I. & Choi, K. Y., 2015 Jan 1, In : Experimental & molecular medicine. 47, p. e152

Research output: Contribution to journalArticle

15 Citations (Scopus)

Extracellular zinc stimulates ERK-dependent activation of p21Cip/WAF1 and inhibits proliferation of colorectal cancer cells

Park, K. S., Ahn, Y., Kim, J. A., Yun, M. S., Seong, B. L. & Choi, K. Y., 2002 Nov, In : British Journal of Pharmacology. 137, 5, p. 597-607 11 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Feature genes of hepatitis B virus-positive hepatocellular carcinoma, established by its molecular discrimination approach using prediction analysis of microarray

Kim, B. Y., Lee, J. G., Park, S., Ahn, J. Y., Ju, Y. J., Chung, J. H., Han, C. J., Jeong, S. H., Yeom, Y. I., Kim, S., Lee, Y. S., Kim, C. M., Eom, E. M., Lee, D. H., Choi, K. Y., Cho, M. H., Suh, K. S., Choi, D. W. & Lee, K. H., 2004 Dec 24, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1739, 1, p. 50-61 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Genes of the Escherichia coli pur regulon are negatively controlled by a repressor-operator interaction

He, B., Shiau, A., Choi, K. Y., Zalkin, H. & Smith, J. M., 1990 Aug 18, In : Journal of Bacteriology. 172, 8, p. 4555-4562 8 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling

Park, P. J., Moon, B. S., Lee, S. H., Kim, S. N., Kim, A. R., Kim, H. J., Park, W. S., Choi, K. Y., Cho, E. G. & Lee, T. R., 2012 Nov 2, In : Life Sciences. 91, 19-20, p. 935-943 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Homozygous deletions of the CDKN2 gene and loss of heterozygosity of 9p in primary hepatocellular carcinoma

Piao, Z., Park, C., Lee, J. S., Yang, C. H., Choi, K. Y. & Kim, H., 1998 Jan 9, In : Cancer Letters. 122, 1-2, p. 201-207 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

House dust mite allergen der f 2 induces interleukin-13 expression by activating the PI3K/Akt pathway

Ro, E. J., Cha, P. H., Kim, H. Y., Cho, Y. H., Park, J. W., Han, J. S. & Choi, K. Y., 2013 May 1, In : Immunologic Research. 56, 1, p. 181-188 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Hovenia dulcis Thunb extract and its ingredient methyl vanillate Activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice

Cha, P. H., Shin, W., Zahoor, M., Kim, H. Y., Min, D. S. & Choi, K. Y., 2014 Jan 22, In : PloS one. 9, 1, e85546.

Research output: Contribution to journalArticle

17 Citations (Scopus)

H-Ras is degraded by Wnt/β-catenin signaling via β-TrCP-mediated polyubiquitylation

Kim, S. E., Yoon, J. Y., Jeong, W. J., Jeon, S. H., Park, Y., Yoon, J. B., Park, Y. N., Kim, H. & Choi, K. Y., 2009 Mar 15, In : Journal of cell science. 122, 6, p. 842-848 7 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Identification of potential Corynebacterium ammoniagenes purine gene regulators using the pur-lacZ reporter in Escherichia coli

Han, R. N., Cho, I. H., Chung, S. O., Han, J. K., Lee, J. H., Kim, S. K. & Choi, K. Y., 2004 Dec 1, In : Journal of microbiology and biotechnology. 14, 6, p. 1249-1255 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification of proteins interacting with the catalytic subunit of PP2A by proteomics

Lee, W. J., Kim, D. U., Lee, M. Y. & Choi, K. Y., 2007 Jan 1, In : Proteomics. 7, 2, p. 206-214 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signaling

Shin, W., Lee, S. K., Hwang, J. H., Park, J. C., Cho, Y. H., Ro, E. J., Song, Y., Seo, H. R. & Choi, K. Y., 2018 Jun 1, In : Experimental and Molecular Medicine. 50, 6, 71.

Research output: Contribution to journalArticle

4 Citations (Scopus)