• 1302 Citations
  • 21 h-Index
19942019

Research output per year

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Research Output

  • 1302 Citations
  • 21 h-Index
  • 58 Article
  • 4 Comment/debate
  • 1 Letter
  • 1 Review article
1994

Ly-6A is required for T cell receptor expression and protein tyrosine kinase fyn activity

Lee, S. K., Su, B., Maher, S. E. & Bothwell, A. L. M., 1994, In : EMBO Journal. 13, 9, p. 2167-2176 10 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

p59fyn tyrosine kinase regulates p56lck tyrosine kinase activity and early TCR-mediated signaling

Lee, S. K., Shaw, A., Maher, S. E. & Bothwell, A. L. M., 1994 Oct, In : International Immunology. 6, 10, p. 1621-1627 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
1998

Induction of late activation events by Igβ signaling subunit of B-cell receptor in Jurkat T-cell without tyrosine phosphorylation

Lim, J. H., Kim, S. W., Song, Y. S. & Lee, S. K., 1998 Aug 31, In : Molecules and cells. 8, 4, p. 408-415 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
5 Citations (Scopus)
1999

Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb

Morio, T., Hanissian, S. H., Bacharier, L. B., Teraoka, H., Nonoyama, S., Seki, M., Kondo, J., Nakano, H., Lee, S. K., Geha, R. S. & Yata, J. I., 1999 Sep, In : Immunity. 11, 3, p. 339-348 10 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)
2002

Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction

Shim, J. H., Lee, H. K., Chang, E. J., Chae, W. J., Han, J. H., Han, D. J., Morio, T., Yang, J. J., Bothwell, A. & Lee, S. K., 2002 Aug, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 16, p. 10617-10622 6 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2003

Tautomycetin as a novel immunosuppressant in transplantation

Han, D. J., Jeong, Y. L., Wee, Y. M., Lee, A. Y., Lee, H. K., Ha, J. C., Lee, S. K. & Kim, S. C., 2003 Feb, In : Transplantation Proceedings. 35, 1, p. 547 1 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2004

Qualitatively differential regulation of T cell activation and apoptosis by T cell receptor ζ chain ITAMs and their tyrosine residues

Chae, W. J., Lee, H. K., Han, J. H., Kim, S. W. V., Bothwell, A. L. M., Morio, T. & Lee, S. K., 2004 Sep, In : International Immunology. 16, 9, p. 1225-1236 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

T cell-specific immunosuppression using tautomycetin or PTD-conjugated protein drugs

Chae, W. J., Choi, J. M., Yang, J. J. & Lee, S. K., 2004 Dec 31, In : Yonsei medical journal. 45, 6, p. 978-990 13 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Trichomonas vaginalis inhibits proinflammatory cytokine production in macrophages by suppressing NF-κB activation

Chang, J. H., Ryang, Y. S., Morio, T., Lee, S. K. & Chang, E. J., 2004 Oct 31, In : Molecules and cells. 18, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2006
21 Citations (Scopus)

Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation

Choi, J. M., Ahn, M. H., Chae, W. J., Jung, Y. G., Park, J. C., Song, H. M., Kim, Y. E., Shin, J. A., Park, C. S., Park, J. W., Park, T. K., Lee, J. H., Seo, B. F., Kim, K. D., Kim, E. S., Lee, D. H., Lee, S. K. & Lee, S. K., 2006 May, In : Nature Medicine. 12, 5, p. 574-579 6 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Proteomic analysis of resting and activated human CD8+ T cells

Koo, J. H., Chae, W. J., Choi, J. M., Nam, H. W., Morio, T., Kim, Y. S., Jang, Y. S., Choi, K. Y., Yang, J. J. & Lee, S. K., 2006 Jun, In : Journal of microbiology and biotechnology. 16, 6, p. 911-920 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tautomycetin inhibits growth of colorectal cancer cells through p21cip/WAF1 induction via the extracellular signal-regulated kinase pathway

Lee, J. H., Lee, J. S., Kim, S. E., Moon, B. S., Kim, Y. C., Lee, S. K., Lee, S. K. & Choi, K. Y., 2006 Dec, In : Molecular Cancer Therapeutics. 5, 12, p. 3222-3231 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells

Chae, W. J., Henegariu, O., Lee, S. K. & Bothwell, A. L. M., 2006 Jun 20, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 25, p. 9631-9636 6 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
2007
41 Citations (Scopus)
2008

Mitochondrial ATP synthase is a target for TNBS-induced protein carbonylation in XS-106 dendritic cells

Jeong, H. J., Tae, H. L., Dong, H. K., Young, H. C., Ju, H. L., Soo, C. K., Lee, S. K., Lee, J. & Lee, M. G., 2008 Jun, In : Proteomics. 8, 12, p. 2384-2393 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis

Choi, J. M., Kim, S. H., Shin, J. H., Gibson, T., Yoon, B. S., Lee, D. H., Lee, S. K., Bothwell, A. L. M., Lim, J. S. & Lee, S. K., 2008 Dec 16, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 50, p. 19875-19880 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2009

Impaired CD4 and CD8 Effector Function and Decreased Memory T Cell Populations in ICOS-Deficient Patients

Takahashi, N., Matsumoto, K., Saito, H., Nanki, T., Miyasaka, N., Kobata, T., Azuma, M., Lee, S. K., Mizutani, S. & Morio, T., 2009 May 1, In : Journal of Immunology. 182, 9, p. 5515-5527 13 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Mesenchymal stem cells pretreated with delivered Hph-1-Hsp70 protein are protected from hypoxia-mediated cell death and rescue heart functions from myocardial injury

Chang, W., Song, B. W., Lim, S., Song, H., Chi, Y. S., Cha, M. J., Dong, H. A., Jung, Y. G., Lee, D. H., Ji, H. C., Choi, K. D., Lee, S. K., Chung, N., Lee, S. K., Jang, Y. & Hwang, K. C., 2009 Sep, In : Stem Cells. 27, 9, p. 2283-2292 10 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Synergistic inhibition of T-cell activation by a cell-permeable ZAP-70 mutant and ctCTLA-4

Kim, K. D., Choi, J. M., Chae, W. J. & Lee, S. K., 2009 Apr 10, In : Biochemical and Biophysical Research Communications. 381, 3, p. 355-360 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2010

Branched oligomerization of cell-permeable peptides markedly enhances the transduction efficiency of adenovirus into mesenchymal stem cells

Park, S. H., Doh, J., Park, S. I., Lim, J. Y., Kim, S. M., Youn, J. I., Jin, H. T., Seo, S. H., Song, M. Y., Sung, S. Y., Kim, M., Hwang, S. J., Choi, J. M., Lee, S. K., Lee, H. Y., Lim, C. L., Chung, Y. J., Yang, D., Kim, H. N., Lee, Z. H. & 3 others, Choi, K. Y., Jeun, S. S. & Sung, Y. C., 2010 Aug, In : Gene Therapy. 17, 8, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Cell-penetrating DNA-binding protein as a safe and efficient naked DNA delivery carrier in vitro and in vivo

Kim, E. S., Yang, S. W., Hong, D. K., Kim, W. T., Kim, H. G. & Lee, S. K., 2010 Jan 29, In : Biochemical and Biophysical Research Communications. 392, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation

Choi, J. M., Shin, J. H., Sohn, M. H., Harding, M. J., Park, J. H., Tobiasova, Z., Kim, D. Y., Maher, S. E., Chae, W. J., Park, S. H., Lee, C. G., Lee, S. K. & Bothwell, A. L. M., 2010 Oct 26, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 43, p. 18575-18580 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Erratum: Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation (Proceedings of the National Academy of Sciences of the United States of America (2010) 107:43 (18575-18580) DOI: 10.1073/pnas.1000400107)

Choi, J. M., Shin, J. H., Sohn, M. H., Harding, M. J., Park, J. H., Tobiasova, Z., Kim, D. Y., Maher, S. E., Chae, W. J., Park, S. H., Lee, C. G., Lee, S. K. & Bothwell, A. L. M., 2010 Dec 14, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 50, p. 21943 1 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Helicobacter pylori proinflammatory protein upregulates NF-κB as a cell-translocating Ser/Thr kinase

Kim, D. J., Park, K. S., Kim, J. H., Yang, S. H., Yoon, J. Y., Han, B. G., Kim, H. S., Lee, S. J., Jang, J. Y., Kim, K. H., Kim, M. J., Song, J. S., Kim, H. J., Park, C. M., Lee, S. K., Il Lee, B. & Suh, S. W., 2010 Dec 14, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 50, p. 21418-21423 6 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Qualitative and quantitative differences in the intensity of Fas-mediated intracellular signals determine life and death in T cells

Shin, M. J., Shim, J. H., Lee, J. Y., Chae, W. J., Lee, H. K., Morio, T., Park, J. H., Chang, E. J. & Lee, S. K., 2010 Sep, In : International Journal of Hematology. 92, 2, p. 262-270 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Quantification of cellular uptake and in vivo tracking of transduction using real-time monitoring

Lee, M. S., Kwon, E. H., Choi, H. S., Kwon, S. H., Lee, C. H., Shim, I. S., Lee, S. K. & Her, S., 2010 Apr 2, In : Biochemical and Biophysical Research Communications. 394, 2, p. 348-353 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The synergistic effect of tautomycetin on cyclosporine a-mediated immunosuppression in a rodent islet allograft model

Wee, Y. M., Choi, M. Y., Kang, C. H., Kim, Y. H., Kim, J. H., Lee, S. K., Yu, S. Y., Kim, S. C. & Han, D. J., 2010 Jul, In : Molecular Medicine. 16, 7-8, p. 298-306 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2011

Calpains are involved in entamoeba histolytica-induced death of ht-29 colonic epithelial cells

Jang, Y. S., Song, K. J., Kim, J. Y., Lee, Y. A., Kim, K. A., Lee, S. K. & Shin, M. H., 2011 Jun, In : Korean Journal of Parasitology. 49, 2, p. 177-180 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Controlled release of cell-permeable gene complex from poly(L-lactide) scaffold for enhanced stem cell tissue engineering

Jung, M. R., Shim, I. K., Kim, E. S., Park, Y. J., Yang, Y. I., Lee, S. K. & Lee, S. J., 2011 Jun 10, In : Journal of Controlled Release. 152, 2, p. 294-302 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Monitoring the status of T-cell activation in a microfluidic system

Park, J. Y., Kim, H. O., Kim, K. D., Kim, S. K., Lee, S. K. & Jung, H., 2011 Jul 7, In : Analyst. 136, 13, p. 2831-2836 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Reactive oxygen species-dependent necroptosis in Jurkat T cells induced by pathogenic free-living Naegleria fowleri

Song, K. J., Jang, Y. S., Lee, Y. A., Kim, K. A., Lee, S. K. & Shin, M. H., 2011 Jul, In : Parasite Immunology. 33, 7, p. 390-400 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2012

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice

Shim, J. H., Greenblatt, M. B., Singh, A., Brady, N., Hu, D., Drapp, R., Ogawa, W., Kasuga, M., Noda, T., Yang, S. H., Lee, S. K., Rebel, V. I. & Glimcher, L. H., 2012 Jan 3, In : Journal of Clinical Investigation. 122, 1, p. 91-106 16 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Alleviation of rheumatoid arthritis by cell-transducible methotrexate upon transcutaneous delivery

Lee, S. W., Kim, J. H., Park, M. C., Park, Y. B., Chae, W. J., Morio, T., Lee, D. H., Yang, S. H., Lee, S. K., Lee, S. K. & Lee, S. K., 2012 Feb, In : Biomaterials. 33, 5, p. 1563-1572 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Application of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis in Korean patients with undifferentiated arthritis

Jung, S. J., Kang, Y., Ha, Y. J., Lee, K. H., Lee, S. W., Lee, S. K. & Park, Y. B., 2012 May, In : Scandinavian Journal of Rheumatology. 41, 3, p. 192-195 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Attenuation of contact hypersensitivity by cell-permeable heat shock protein 70 in BALB/c mouse model

Park, J. M., Je, J. H., Wu, W. H., Jee, H. J., Lee, S. K. & Lee, M. G., 2012 Dec, In : Experimental dermatology. 21, 12, p. 969-971 3 p.

Research output: Contribution to journalLetter

7 Citations (Scopus)

Cell permeable NFAT inhibitory peptide Sim-2-VIVIT inhibits T-cell activation and alleviates allergic airway inflammation and hyper-responsiveness

Choi, J. M., Sohn, J. H., Park, T. Y., Park, J. W. & Lee, S. K., 2012 Apr 30, In : Immunology Letters. 143, 2, p. 170-176 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Erratum: Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice (Journal of Clinical Investigation (2012) 122, 1 (91-106) DOI: 10.1172/JCI59466)

Shim, J. H., Greenblatt, M. B., Singh, A., Brady, N., Hu, D., Drapp, R., Ogawa, W., Kasuga, M., Noda, T., Yang, S. H., Lee, S. K., Rebel, V. I. & Glimcher, L. H., 2012 May 1, In : Journal of Clinical Investigation. 122, 5, p. 1948 1 p.

Research output: Contribution to journalComment/debate

Impaired cell adhesion, apoptosis, and signaling in WASP gene-disrupted Nalm-6 pre-B cells and recovery of cell adhesion using a transducible form of WASp

Sato, R., Honda, F., Koyama, H., Iiizumi, S., Lee, S. K., Mizutani, S., Kim, E. S., Adachi, N. & Morio, T., 2012 Mar, In : International Journal of Hematology. 95, 3, p. 299-310 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils

Honda, F., Kano, H., Kanegane, H., Nonoyama, S., Kim, E. S., Lee, S. K., Takagi, M., Mizutani, S. & Morio, T., 2012 Apr, In : Nature Immunology. 13, 4, p. 369-378 10 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)

Transducible form of p47 phox and p67 phox compensate for defective NADPH oxidase activity in neutrophils of patients with chronic granulomatous disease

Honda, F., Hane, Y., Toma, T., Yachie, A., Kim, E. S., Lee, S. K., Takagi, M., Mizutani, S. & Morio, T., 2012 Jan 6, In : Biochemical and Biophysical Research Communications. 417, 1, p. 162-168 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2013

Alleviation of abnormal synaptic neurotransmitter release by cell-permeable form of the truncated SNAP-25 upon transcutaneous delivery

Park, T. Y., Shin, M. J., Park, S. D. & Lee, S. K., 2013 May 24, In : Neuroscience Letters. 543, p. 52-57 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin

Park, T. Y., Kim, S. H., Shin, Y. C., Lee, N. H., Lee, R. K. C., Shim, J. H., Glimcher, L. H., Mook-Jung, I., Cheong, E., Kim, W. K., Honda, F., Morio, T., Lim, J. S. & Lee, S. K., 2013 Mar 28, In : Journal of Controlled Release. 166, 3, p. 307-315 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The Antioxidative Effect of Heat-Shock Protein 70 in Dendritic Cells

Je, J. H., Kim, D. Y., Roh, H. J., Pak, C., Kim, D. H., Byamba, D., Jee, H., Kim, T. G., Park, J. M., Lee, S. K. & Lee, M. G., 2013 Sep, In : Scandinavian Journal of Immunology. 78, 3, p. 238-247 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014

Erratum: Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells(Biochem. Biophys. Res. Commun. (2014)451(1-7))

Park, J. H., Ko, J. S., Shin, Y., Cho, J. Y., Oh, H. A., Bothwell, A. L. M. & Lee, S. K., 2014 Sep 12, In : Biochemical and Biophysical Research Communications. 452, 1, p. 205 1 p.

Research output: Contribution to journalComment/debate

Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells

Park, J. H., Ko, J. S., Shin, Y., Cho, J. Y., Oh, H. A., Bothwell, A. M. & Lee, S. K., 2014 Aug 15, In : Biochemical and Biophysical Research Communications. 451, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

PLCδ1 protein rescues ischemia-reperfused heart by the regulation of calcium homeostasis

Lim, S., Chang, W., Cha, M. J., Song, B. W., Ham, O., Lee, S. Y., Lee, C., Park, J. H., Lee, S. K., Jang, Y. & Hwang, K. C., 2014 Jun, In : Molecular Therapy. 22, 6, p. 1110-1121 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells

Park, T. Y., Park, S. D., Cho, J. Y., Moon, J. S., Kim, N. Y., Park, K., Seong, R. H., Lee, S. W., Morio, T., Bothwell, A. L. M. & Lee, S. K., 2014 Dec 30, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 52, p. 18673-18678 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Skin-penetrating methotrexate alleviates imiquimod-induced psoriasiform dermatitis via decreasing IL-17-producing gamma delta T cells

Byamba, D., Kim, D. Y., Kim, D. S., Kim, T. G., Jee, H., Kim, S. H., Park, T. Y., Yang, S. H., Lee, S. K. & Lee, M. G., 2014 Jul, In : Experimental dermatology. 23, 7, p. 492-496 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)