• 1254 Citations
  • 21 h-Index
20082020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Red ginseng improves exercise endurance by promoting mitochondrial biogenesis and myoblast differentiation

Shin, E. J., Jo, S., Choi, S., Cho, C. W., Lim, W. C., Hong, H. D., Lim, T. G., Jang, Y. J., Jang, M., Byun, S. & Rhee, Y., 2020 Feb 16, In : Molecules. 25, 4, 865.

Research output: Contribution to journalArticle

Open Access

Smilax guianensis Vitman Extract Prevents LPS-Induced Inflammation by Inhibiting the NF-κB Pathway in RAW 264.7 Cells

Kim, J. G., Kim, M. J., Lee, J. S., Sydara, K., Lee, S., Byun, S. & Jung, S. K., 2020 Jun 28, In : Journal of microbiology and biotechnology. 30, 6, p. 822-829 8 p.

Research output: Contribution to journalArticle

Open Access
2019

Caffeic acid phenethyl ester inhibits uv-induced mmp-1 expression by targeting histone acetyltransferases in human skin

Shin, E. J., Jo, S., Choi, H. K., Cho, S., Byun, S. & Lim, T. G., 2019 Jun 2, In : International journal of molecular sciences. 20, 12, 3055.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Dihydrocapsaicin inhibits epithelial cell transformation through targeting amino acid signaling and c-Fos expression

Lee, J. S., Kim, Y. A., Jang, Y. J., Oh, Y. & Byun, S., 2019 Jun, In : Nutrients. 11, 6, 1269.

Research output: Contribution to journalArticle

Open Access

Effect of differential thermal drying conditions on the immunomodulatory function of ginger

Lee, J. S., Kim, B., Kim, J. H., Jeong, M., Lim, S. & Byun, S., 2019 Jan 1, In : Journal of microbiology and biotechnology. 29, 7, p. 1053-1060 8 p.

Research output: Contribution to journalArticle

Enhancing immunomodulatory function of red ginseng through fermentation using Bifidobacterium animalis subsp. Lactis LT 19-2

Kim, J. H., Doo, E. H., Jeong, M., Kim, S., Lee, Y. Y., Yang, J., Lee, J. S., Kim, J. H., Lee, K. W., Huh, C. S. & Byun, S., 2019 Jul, In : Nutrients. 11, 7, 1481.

Research output: Contribution to journalArticle

Open Access

Heat-Killed Lactobacillus plantarum KCTC 13314BP Enhances Phagocytic Activity and Immunomodulatory Effects Via Activation of MAPK and STAT3 Pathways

Jeong, M., Kim, J. H., Yang, H., Kang, S. D., Song, S., Lee, D., Lee, J. S., Yoon Park, J. H., Byun, S. & Lee, K. W., 2019 Aug 28, In : Journal of microbiology and biotechnology. 29, 8, p. 1248-1254 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Non-enzymatic softening of Calendula officinalis L. Petals and its anti-skin aging effect for food materialization

Lim, S., Choi, S., Lee, P., Kim, H. S., Lee, D. Y. & Byun, S., 2019, In : Korean Journal of Food Science and Technology. 51, 3, p. 243-247 5 p.

Research output: Contribution to journalArticle

Quercetin directly targets JAK2 and PKCδ and prevents UV-induced photoaging in human skin

Shin, E. J., Lee, J. S., Hong, S., Lim, T. G. & Byun, S., 2019 Nov 1, In : International journal of molecular sciences. 20, 21, 5262.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

The ginsenoside metabolite compound K inhibits hormone-independent breast cancer through downregulation of cyclin D1

Lee, S. J., Lee, J. S., Lee, E., Lim, T. G. & Byun, S., 2018 Jul, In : Journal of Functional Foods. 46, p. 159-166 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c-Fos Degradation

Shin, S. H., Lee, S. R., Lee, E., Kim, K. H. & Byun, S., 2017 Jul 28, In : Journal of Natural Products. 80, 7, p. 2124-2130 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Induction of synthetic lethality by natural compounds targeting cancer signaling

Farrand, L. & Byun, S., 2017 Aug 1, In : Current Pharmaceutical Design. 23, 29, p. 4311-4320 10 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Therapeutic implications of autophagy inducers in immunological disorders, infection, and cancer

Byun, S., Lee, E. & Lee, K. W., 2017 Sep 12, In : International journal of molecular sciences. 18, 9, A1959.

Research output: Contribution to journalReview article

Open Access
15 Citations (Scopus)

TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway

Bae, S. Y., Byun, S., Bae, S. H., Min, D. S., Woo, H. A. & Lee, K., 2017 May 4, In : Autophagy. 13, 5, p. 820-833 14 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
2016

Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling

Hwang, S. Y., Deng, X., Byun, S., Lee, C., Lee, S. J., Suh, H., Zhang, J., Kang, Q., Zhang, T., Westover, K. D., Mandinova, A. & Lee, S. W., 2016 Jun 28, In : Cell Reports. 16, 1, p. 28-36 9 p.

Research output: Contribution to journalArticle

Open Access
26 Citations (Scopus)

Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization

Byun, S., Shin, S. H., Park, J., Lim, S., Lee, E., Lee, C., Sung, D., Farrand, L., Lee, S. R., Kim, K. H., Dong, Z., Lee, S. W. & Lee, K. W., 2016 May 1, In : Molecular Nutrition and Food Research. 60, 5, p. 1068-1078 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The NADPH oxidase inhibitor apocynin inhibits UVB-induced skin carcinogenesis

Byun, S., Lee, E., Jang, Y. J., Kim, Y. & Lee, K. W., 2016 Jun 1, In : Experimental dermatology. 25, 6, p. 489-491 3 p.

Research output: Contribution to journalLetter

Open Access
4 Citations (Scopus)
2015

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

Yoon, K. W., Byun, S., Kwon, E., Hwang, S. Y., Chu, K., Hiraki, M., Jo, S. H., Weins, A., Hakroush, S., Cebulla, A., Sykes, D. B., Greka, A., Mundel, P., Fisher, D. E., Mandinova, A. & Lee, S. W., 2015 Jul 31, In : Science. 349, 6247, 1261669.

Research output: Contribution to journalArticle

Open Access
91 Citations (Scopus)

Identification of a dual inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) pathways

Byun, S., Lim, S., Mun, J. Y., Kim, K. H., Ramadhar, T. R., Farrand, L., Shin, S. H., Thimmegowda, N. R., Lee, H. J., Frank, D. A., Clardy, J., Lee, S. W. & Lee, K. W., 2015 Sep 25, In : Journal of Biological Chemistry. 290, 39, p. 23553-23562 10 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Losing p53 loosens up ER-stress

Byun, S., Namba, T. & Lee, S. W., 2015, In : Aging. 7, 11, p. 895-896 2 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway

Namba, T., Chu, K., Kodama, R., Byun, S., Yoon, K. W., Hiraki, M., Mandinova, A. & Lee, S. W., 2015, In : Oncotarget. 6, 24, p. 19990-20001 12 p.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

Proteomics in Understanding the Molecular Basis of Phytochemicals for Health

Kwon, J. Y., Byun, S. & Lee, K. W., 2015 Oct 5, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods: Second Edition. Wiley-Blackwell, p. 328-337 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis

Hiraki, M., Hwang, S. Y., Cao, S., Ramadhar, T. R., Byun, S., Yoon, K. W., Lee, J. H., Chu, K., Gurkar, A. U., Kolev, V., Zhang, J., Namba, T., Murphy, M. E., Newman, D. J., Mandinova, A., Clardy, J. & Lee, S. W., 2015 Sep 17, In : Chemistry and Biology. 22, 9, p. 1206-1216 11 p.

Research output: Contribution to journalArticle

Open Access
36 Citations (Scopus)

The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1

Byun, S., Shin, S. H., Lee, E., Lee, J., Lee, S. Y., Farrand, L., Jung, S. K., Cho, Y. Y., Um, S. J., Sin, H. S., Kwon, Y. J., Zhang, C., Benjamin, K. T., Ann, M. B., Lee, H. J., Lee, K. W. & Dong, Z., 2015 Dec 1, In : Carcinogenesis. 36, 12, p. 1580-1589 10 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2014

The diarylheptanoid hirsutenone sensitizes chemoresistant ovarian cancer cells to cisplatin via modulation of apoptosis-inducing factor and X-linked inhibitor of apoptosis

Farrand, L., Kim, J. Y., Byun, S., Im-Aram, A., Lee, J., Suh, J. Y., Lee, K. W., Lee, H. J. & Tsang, B. K., 2014 Jan 17, In : Journal of Biological Chemistry. 289, 3, p. 1723-1731 9 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

The P110 subunit of PI3-K is a therapeutic target of acacetin in skin cancer

Jung, S. K., Kim, J. E., Lee, S. Y., Lee, M. H., Byun, S., Kim, Y. A., Lim, T. G., Reddy, K., Huang, Z., Bode, A. M., Lee, H. J., Lee, K. W. & Dong, Z., 2014 Jan, In : Carcinogenesis. 35, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)
2013

Autophagy and Cellular Senescence Mediated by Sox2 Suppress Malignancy of Cancer Cells

Cho, Y. Y., Kim, D. J., Lee, H. S., Jeong, C. H., Cho, E. J., Kim, M. O., Byun, S., Lee, K. Y., Yao, K., Carper, A., Langfald, A., Bode, A. M. & Dong, Z., 2013 Feb 25, In : PloS one. 8, 2, e57172.

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)

CDIP1-BAP31 Complex Transduces Apoptotic Signals from Endoplasmic Reticulum to Mitochondria under Endoplasmic Reticulum Stress

Namba, T., Tian, F., Chu, K., Hwang, S. Y., Yoon, K. W., Byun, S., Hiraki, M., Mandinova, A. & Lee, S. W., 2013 Oct 18, In : Cell Reports. 5, 2, p. 331-339 9 p.

Research output: Contribution to journalArticle

Open Access
44 Citations (Scopus)

CDK2 and mTOR are direct molecular targets of isoangustone A in the suppression of human prostate cancer cell growth

Lee, E., Son, J. E., Byun, S., Lee, S. J., Kim, Y. A., Liu, K., Kim, J., Lim, S. S., Park, J. H. Y., Dong, Z., Lee, K. W. & Lee, H. J., 2013 Oct 1, In : Toxicology and Applied Pharmacology. 272, 1, p. 12-20 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Isoangustone A, a novel licorice compound, inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma

Song, N. R., Lee, E., Byun, S., Kim, J. E., Mottamal, M., Park, J. H. Y., Lim, S. S., Bode, A. M., Lee, H. J., Lee, K. W. & Dong, Z., 2013 Dec, In : Cancer Prevention Research. 6, 12, p. 1293-1303 11 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Luteolin suppresses UVB-induced photoageing by targeting JNK1 and p90RSK2

Lim, S. H., Jung, S. K., Byun, S., Lee, E. J., Hwang, J. A., Seo, S. G., Kim, Y. A., Yu, J. G., Lee, K. W. & Lee, H. J., 2013 May 1, In : Journal of Cellular and Molecular Medicine. 17, 5, p. 672-680 9 p.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

New perspectives in chemoresistant ovarian cancer

Ali, A. Y., Farrand, L., Kim, J. Y., Im-Aram, A., Byun, S., Lai-Han Leung, E., Joo Lee, H. & Tsang, B. K., 2013 Jan 1, Ovarian Toxicology, Second Edition. CRC Press, p. 283-314 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission

Farrand, L., Byun, S., Kim, J. Y., Im-Aram, A., Lee, J., Lim, S., Lee, K. W., Suh, J. Y., Lee, H. J. & Tsang, B. K., 2013 Aug 16, In : Journal of Biological Chemistry. 288, 33, p. 23740-23750 11 p.

Research output: Contribution to journalArticle

Open Access
53 Citations (Scopus)

Raf and PI3K are the molecular targets for the anti-metastatic effect of luteolin

Kim, H. Y., Jung, S. K., Byun, S., Son, J. E., Oh, M. H., Lee, J., Kang, M. J., Heo, Y. S., Lee, K. W. & Lee, H. J., 2013 Oct 1, In : Phytotherapy Research. 27, 10, p. 1481-1488 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Src kinase is a direct target of apigenin against UVB-induced skin inflammation

Byun, S., Park, J., Lee, E., Lim, S., Yu, J. G., Lee, S. J., Chen, H., Dong, Z., Lee, K. W. & Lee, H. J., 2013 Feb 1, In : Carcinogenesis. 34, 2, p. 397-405 9 p.

Research output: Contribution to journalArticle

Open Access
48 Citations (Scopus)

Structural and functional analysis of the natural JNK1 inhibitor quercetagetin

Baek, S., Kang, N. J., Popowicz, G. M., Arciniega, M., Jung, S. K., Byun, S., Song, N. R., Heo, Y. S., Kim, B. Y., Lee, H. J., Holak, T. A., Augustin, M., Bode, A. M., Huber, R., Dong, Z. & Lee, K. W., 2013 Jan 23, In : Journal of Molecular Biology. 425, 2, p. 411-423 13 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

USP8 is a novel target for overcoming gefitinib resistance in lung cancer

Byun, S., Lee, S. Y., Lee, J., Jeong, C. H., Farrand, L., Lim, S., Reddy, K., Kim, J. Y., Lee, M. H., Lee, H. J., Bode, A. M., Lee, K. W. & Dong, Z., 2013 Jul 15, In : Clinical Cancer Research. 19, 14, p. 3894-3904 11 p.

Research output: Contribution to journalArticle

Open Access
62 Citations (Scopus)
2012

Inhibitory effect of ERK1/2 and AP-1 by hyperoside isolated from Acanthopanax sessiliflorus

Jung, S. K., Lim, T. G., Kim, J. E., Byun, S., Kim, G. W., Choi, J. N., Lee, C. H., Kim, B. Y., Lee, K. W. & Lee, H. J., 2012 Feb 15, In : Food Chemistry. 130, 4, p. 915-920 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Molecular determinants of ovarian cancer chemoresistance: New insights into an old conundrum

Ali, A. Y., Farrand, L., Kim, J. Y., Byun, S., Suh, J. Y., Lee, H. J. & Tsang, B. K., 2012 Oct, In : Annals of the New York Academy of Sciences. 1271, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2011

7,3',4'-trihydroxyisoflavone, a metabolite of the soy isoflavone Daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4

Lee, D. E., Lee, K. W., Byun, S., Jung, S. K., Song, N., Lim, S. H., Heo, Y. S., Kim, J. E., Kang, N. J., Kim, B. Y., Bowden, G. T., Bode, A. M., Lee, H. J. & Dong, Z., 2011 Apr 22, In : Journal of Biological Chemistry. 286, 16, p. 14246-14256 11 p.

Research output: Contribution to journalArticle

Open Access
50 Citations (Scopus)

Kaempferol attenuates 4-hydroxynonenal-induced apoptosis in PC12 cells by directly inhibiting NADPH oxidase

Jang, Y. J., Kim, J., Shim, J., Kim, J., Byun, S., Oak, M. H., Lee, K. W. & Lee, H. J., 2011 Jun, In : Journal of Pharmacology and Experimental Therapeutics. 337, 3, p. 747-754 8 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2010

5-Deoxykaempferol plays a potential therapeutic role by targeting multiple signaling pathways in skin cancer

Lee, K. M., Lee, K. W., Byun, S., Jung, S. K., Seo, S. K., Heo, Y. S., Bode, A. M., Lee, H. J. & Dong, Z., 2010 Apr, In : Cancer Prevention Research. 3, 4, p. 454-465 12 p.

Research output: Contribution to journalArticle

Open Access
26 Citations (Scopus)

Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1

Hwang, M. K., Bode, A. M., Byun, S., Song, N. R., Joo Lee, H., Lee, K. W. & Dong, Z., 2010 Sep 1, In : Cancer Research. 70, 17, p. 6859-6869 11 p.

Research output: Contribution to journalArticle

Open Access
56 Citations (Scopus)

Luteolin inhibits protein kinase Cε and c-Src activities and UVB-induced skin cancer

Byun, S., Lee, K. W., Jung, S. K., Lee, E. J., Hwang, M. K., Lim, S. H., Bode, A. M., Lee, H. J. & Dong, Z., 2010 Mar 15, In : Cancer Research. 70, 6, p. 2415-2423 9 p.

Research output: Contribution to journalArticle

Open Access
87 Citations (Scopus)

Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf

Jung, S. K., Lee, K. W., Kim, H. Y., Oh, M. H., Byun, S., Lim, S. H., Heo, Y. S., Kang, N. J., Bode, A. M., Dong, Z. & Lee, H. J., 2010 May 15, In : Biochemical Pharmacology. 79, 10, p. 1455-1461 7 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells

Choi, K. H., Kim, J. E., Song, N. R., Son, J. E., Hwang, M. K., Byun, S., Kim, J. H., Lee, K. W. & Lee, H. J., 2010 Mar 1, In : Cardiovascular Research. 85, 4, p. 836-844 9 p.

Research output: Contribution to journalArticle

Open Access
76 Citations (Scopus)
2009

Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo

Jung, S. K., Lee, K. W., Byun, S., Lee, E. J., Kim, J. E., Bode, A. M., Dong, Z. & Lee, H. J., 2009 Dec 11, In : Carcinogenesis. 31, 5, p. 911-917 7 p.

Research output: Contribution to journalArticle

Open Access
51 Citations (Scopus)
2008

Myricetin suppresses UVB-induced skin cancer by targeting Fyn

Sung, K. J., Ki, W. L., Byun, S., Nam, J. K., Sung, H. L., Heo, Y. S., Bode, A. M., Bowden, G. T., Hyong, J. L. & Dong, Z., 2008 Jul 15, In : Cancer Research. 68, 14, p. 6021-6029 9 p.

Research output: Contribution to journalArticle

Open Access
102 Citations (Scopus)