• 895 Citations
  • 16 h-Index
20032018
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Research Output 2003 2018

  • 895 Citations
  • 16 h-Index
  • 28 Article
  • 2 Comment/debate
  • 1 Review article
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Article
2018

Conformation-Specific Spectroscopy of Asparagine-Containing Peptides: Influence of Single and Adjacent Asn Residues on Inherent Conformational Preferences

Blodgett, K. N., Fischer, J. L., Lee, J., Choi, S. H. & Zwier, T. S., 2018 Nov 8, In : Journal of Physical Chemistry A. 122, 44, p. 8762-8775 14 p.

Research output: Contribution to journalArticle

Asparagine
peptides
Conformations
Spectroscopy
Peptides
2 Citations (Scopus)

Conformer-Specific and Diastereomer-Specific Spectroscopy of αβα Synthetic Foldamers: Ac-Ala-βACHC-Ala-NHBn

Blodgett, K. N., Zhu, X., Walsh, P. S., Sun, D., Lee, J., Choi, S. H. & Zwier, T. S., 2018 Apr 12, In : Journal of Physical Chemistry A. 122, 14, p. 3697-3710 14 p.

Research output: Contribution to journalArticle

caps
Amides
helices
amides
Conformations
1 Citation (Scopus)

Cooperative Effect of the Two Hydrogen Bonding Types on 11/9-Helical Folding of α/β-Peptides

Jang, G., Lee, M., Lee, J., Shim, J., Kang, P., Choi, M. G. & Choi, S. H., 2018 Feb 1, In : Bulletin of the Korean Chemical Society. 39, 2, p. 244-249 6 p.

Research output: Contribution to journalArticle

Hydrogen bonds
Peptides
Nuclear magnetic resonance
Depsipeptides
X rays

Crystal Packing-induced Dimorphism of 12/10-Helical β-Peptides with Dynamic Folding Propensity

Jang, G., Shin, S., Guzei, I. A., Jung, S., Choi, M. G. & Choi, S. H., 2018 Feb 1, In : Bulletin of the Korean Chemical Society. 39, 2, p. 265-268 4 p.

Research output: Contribution to journalArticle

Crystal structure
Peptides
Crystals
1 Citation (Scopus)

Side chain-specific 11/9-helix propensity of α/β-peptides with alternating residue types

Lee, J., Shim, J., Kang, P., Choi, M. G. & Choi, S. H., 2018 Jan 1, In : Organic and Biomolecular Chemistry. 16, 3, p. 433-438 6 p.

Research output: Contribution to journalArticle

helices
peptides
Oligomers
Peptides
Stereochemistry
2016
13 Citations (Scopus)

12/10-Helical β-Peptide with Dynamic Folding Propensity: Coexistence of Right- and Left-Handed Helices in an Enantiomeric Foldamer

Shin, S., Lee, M., Guzei, I. A., Kang, Y. K. & Choi, S. H., 2016 Oct 12, In : Journal of the American Chemical Society. 138, 40, p. 13390-13395 6 p.

Research output: Contribution to journalArticle

Carboxylic Acids
Carboxylic acids
Peptides
Oligomers
Conformations
1 Citation (Scopus)

Helical α/β-depsipeptides with alternating residue types: Conformational change from the 11-helix to the 14/15-helix

Lee, J., Jang, G., Kang, P., Choi, M-G. & Choi, S. H., 2016 Jan 1, In : Organic and Biomolecular Chemistry. 14, 36, p. 8438-8442 5 p.

Research output: Contribution to journalArticle

Depsipeptides
helices
Conformations
Cycloleucine
lactic acid
6 Citations (Scopus)

Stabilization of 11/9-helical α/β-peptide foldamers in protic solvents

Lee, M., Shim, J., Kang, P., Choi, M-G. & Choi, S. H., 2016 May 1, In : Chemical Communications. 52, 35, p. 5950-5952 3 p.

Research output: Contribution to journalArticle

Peptides
Stabilization
Acids
Conformations
Amino Acids
2015
4 Citations (Scopus)

Cis-2-Aminocyclohex-4-enecarboxylic acid as a new building block of helical foldamers

Kwon, S., Kang, P., Choi, M-G. & Choi, S. H., 2015 May 1, In : New Journal of Chemistry. 39, 5, p. 3221-3224 4 p.

Research output: Contribution to journalArticle

Acids
Alanine
Conformations
Peptides
Amino acids
2014
19 Citations (Scopus)

Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors

Khanfar, M. A., Quinti, L., Wang, H., Choi, S. H., Kazantsev, A. G. & Silverman, R. B., 2014 Apr 9, In : European Journal of Medicinal Chemistry. 76, p. 414-426 13 p.

Research output: Contribution to journalArticle

Sirtuin 2
Benzamides
Assays
Huntington Disease
Cells
13 Citations (Scopus)

Helical folding of α/β-peptides containing β-amino acids with an eight-membered ring constraint

Lee, W., Kwon, S., Kang, P., Guzei, I. A. & Choi, S. H., 2014 May 7, In : Organic and Biomolecular Chemistry. 12, 17, p. 2641-2644 4 p.

Research output: Contribution to journalArticle

folding
peptides
amino acids
Cyclic Amino Acids
Amino Acids
2013
19 Citations (Scopus)

Structural characterization of peptide oligomers containing (1R,2S)-2-aminocyclohexanecarboxylic acid (cis-ACHC)

Choi, S. H., Ivancic, M., Guzei, I. A. & Gellman, S. H., 2013 Jun 1, In : European Journal of Organic Chemistry. 17, p. 3464-3469 6 p.

Research output: Contribution to journalArticle

oligomers
Oligomers
peptides
Conformations
Peptides
31 Citations (Scopus)

Structural characterization of α/β-peptides having alternating residues: X-ray structures of the 11/9-helix from crystals of racemic mixtures

Lee, M., Shim, J., Kang, P., Guzei, I. A. & Choi, S. H., 2013 Nov 25, In : Angewandte Chemie - International Edition. 52, 48, p. 12564-12567 4 p.

Research output: Contribution to journalArticle

Peptides
X rays
Crystals
X ray crystallography
Conformations
2012
12 Citations (Scopus)

3-(N-Arylsulfamoyl)benzamides, inhibitors of human sirtuin type 2 (SIRT2)

Choi, S. H., Quinti, L., Kazantsev, A. G. & Silverman, R. B., 2012 Apr 15, In : Bioorganic and Medicinal Chemistry Letters. 22, 8, p. 2789-2793 5 p.

Research output: Contribution to journalArticle

Sirtuin 2
Benzamides
Methylation
Drug Design
Neuroprotective Agents
55 Citations (Scopus)

Single-conformation infrared spectra of model peptides in the amide i and amide II regions: Experiment-based determination of local mode frequencies and inter-mode coupling

Buchanan, E. G., James, W. H., Choi, S. H., Guo, L., Gellman, S. H., Müller, C. W. & Zwier, T. S., 2012 Sep 7, In : Journal of Chemical Physics. 137, 9, 094301.

Research output: Contribution to journalArticle

Amides
coupled modes
amides
peptides
Conformations
95 Citations (Scopus)

The Sirtuin 2 Inhibitor AK-7 Is Neuroprotective in Huntington's Disease Mouse Models

Chopra, V., Quinti, L., Kim, J., Vollor, L., Narayanan, K. L., Edgerly, C., Cipicchio, P. M., Lauver, M. A., Choi, S. H., Silverman, R. B., Ferrante, R. J., Hersch, S. & Kazantsev, A. G., 2012 Dec 27, In : Cell Reports. 2, 6, p. 1492-1497 6 p.

Research output: Contribution to journalArticle

Sirtuin 2
Huntington Disease
Brain
Genetic Models
Invertebrates
2010
33 Citations (Scopus)

Crystallographic characterization of 12-helical secondary structure in β-peptides containing side chain groups

Choi, S. H., Guzei, I. A., Spencer, L. C. & Gellman, S. H., 2010 Oct 6, In : Journal of the American Chemical Society. 132, 39, p. 13879-13885 7 p.

Research output: Contribution to journalArticle

Peptides
Cycloleucine
Acids
Hydrogen
Crystal structure
73 Citations (Scopus)

Helix formation in preorganized β/γ-peptide foldamers: Hydrogen-bond analogy to the α-helix without α-amino acid residues

Guo, L., Almeida, A. M., Zhang, W., Reidenbach, A. G., Choi, S. H., Guzei, I. A. & Gellman, S. H., 2010 Jun 16, In : Journal of the American Chemical Society. 132, 23, p. 7868-7869 2 p.

Research output: Contribution to journalArticle

Peptides
Amino acids
Hydrogen
Hydrogen bonds
Amino Acids
30 Citations (Scopus)

Laser spectroscopy of conformational constrained α/β-peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe

James, W. H., Baquero, E. E., Choi, S. H., Gellman, S. H. & Zwier, T. S., 2010 Mar 1, In : Journal of Physical Chemistry A. 114, 3, p. 1581-1591 11 p.

Research output: Contribution to journalArticle

Cycloleucine
Laser spectroscopy
laser spectroscopy
peptides
Peptides
2009
35 Citations (Scopus)

Crystallographic characterization of helical secondary structures in 2:1 and 1:2 α/Β-peptides

Choi, S. H., Guzei, I. A., Spencer, L. C. & Gellman, S. H., 2009 Mar 4, In : Journal of the American Chemical Society. 131, 8, p. 2917-2924 8 p.

Research output: Contribution to journalArticle

Peptides
Hydrogen
Cycloleucine
Hydrogen bonds
Oligomers
44 Citations (Scopus)

Single-conformation and diastereomer specific ultraviolet and infrared spectroscopy of model synthetic foldamers: α/β-peptides

James, W. H., Baquero, E. E., Shubert, V. A., Choi, S. H., Gellman, S. H. & Zwier, T. S., 2009 May 13, In : Journal of the American Chemical Society. 131, 18, p. 6574-6590 17 p.

Research output: Contribution to journalArticle

Ultraviolet spectroscopy
Amides
Peptides
Conformations
Infrared spectroscopy
2008
65 Citations (Scopus)

Crystallographic characterization of helical secondary structures in α/β-peptides with 1: 1 residue alternation

Soo, H. C., Guzei, I. A., Spencer, L. C. & Gellman, S. H., 2008 May 21, In : Journal of the American Chemical Society. 130, 20, p. 6544-6550 7 p.

Research output: Contribution to journalArticle

Peptides
Hydrogen
Hydrogen bonds
Oligomers
Conformations
49 Citations (Scopus)

Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: β-peptides Ac-β3-hPhe- β3-hAla-NHMe and Ac-β3-hAla-β3- hPhe-NHMe

Baquero, E. E., James, W. H., Soo, H. C., Gellman, S. H. & Zwier, T. S., 2008 Apr 9, In : Journal of the American Chemical Society. 130, 14, p. 4795-4807 13 p.

Research output: Contribution to journalArticle

Ultraviolet spectroscopy
Peptides
Conformations
Infrared spectroscopy
Spectrum Analysis
53 Citations (Scopus)

Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: β-peptides Ac-β3-hPhe-NHMe and Ac-β3-hTyr-NHMe

Baquero, E. E., James, W. H., Soo, H. C., Gellman, S. H. & Zwier, T. S., 2008 Apr 9, In : Journal of the American Chemical Society. 130, 14, p. 4784-4794 11 p.

Research output: Contribution to journalArticle

Ultraviolet spectroscopy
Peptides
Conformations
Infrared spectroscopy
Spectrum Analysis
2007
49 Citations (Scopus)

Crystallographic characterization of the α/β-peptide 14/15-helix

Choi, S. H., Guzei, I. A. & Gellman, S. H., 2007 Nov 14, In : Journal of the American Chemical Society. 129, 45, p. 13780-13781 2 p.

Research output: Contribution to journalArticle

Peptides
Conformations
Cyclopentanes
Oligomers
Amino acids
2006
75 Citations (Scopus)

New helical foldamers: Heterogeneous backbones with 1:2 and 2:1 α:β-amino acid residue patterns

Schmitt, M. A., Choi, S. H., Guzei, I. A. & Gellman, S. H., 2006 Apr 12, In : Journal of the American Chemical Society. 128, 14, p. 4538-4539 2 p.

Research output: Contribution to journalArticle

Oligopeptides
X ray crystallography
X Ray Crystallography
Oligomers
Scaffolds
2005
100 Citations (Scopus)

Residue requirements for helical folding in short α/β-peptides: Crystallographic characterization of the 11-helix in an optimized sequence

Schmitt, M. A., Choi, S. H., Guzei, I. A. & Gellman, S. H., 2005 Sep 28, In : Journal of the American Chemical Society. 127, 38, p. 13130-13131 2 p.

Research output: Contribution to journalArticle

Peptides
Amino acids
Amino Acids
Acyclic Acids
Amino Acid Substitution
2003
15 Citations (Scopus)

An efficient synthesis of 3(S)-aminopiperidine-5(R)-carboxylic acid as a cyclic β,γ′-diamino acid

Park, J. S., Yeom, C. E., Choi, S. H., Ahn, Y. S., Ro, S., Jeon, Y. H., Shin, D. K. & Kim, B. M., 2003 Feb 17, In : Tetrahedron Letters. 44, 8, p. 1611-1614 4 p.

Research output: Contribution to journalArticle

Cyclic Amino Acids
Carboxylic Acids
Acids
Dicarboxylic Acids
Enzymatic hydrolysis