• 3929 Citations
  • 25 h-Index
1989 …2017

Research output per year

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Research Output

  • 3929 Citations
  • 25 h-Index
  • 48 Article
  • 1 Chapter
  • 1 Paper
  • 1 Review article
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Article
2017

Kinetic analysis of de novo centriole assembly in heat-shocked mammalian cells

Baek, I. K., Jang, Y. K., Lee, T. H. & Lee, J. H., 2017 Jan 1, In : Cytoskeleton. 74, 1, p. 18-28 11 p.

Research output: Contribution to journalArticle

2013

UNC119a bridges the transmission of Fyn signals to RAB11, leading to the completion of cytokinesis

Lee, Y. K., Chung, S., Baek, I. K., Lee, T. H., Paik, S. Y. & Lee, J. H., 2013 Apr 15, In : Cell Cycle. 12, 8, p. 1303-1315 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2011

A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration

Jin, H. S., Park, H. S., Shin, J. H., Kim, D. H., Jun, S. H., Lee, C. J. & Lee, T. H., 2011 Sep 2, In : Biochemical and Biophysical Research Communications. 412, 3, p. 454-459 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Antiangiogenic kringles derived from human plasminogen and apolipoprotein(a) inhibit fibrinolysis through a mechanism that requires a functional lysine-binding site

Ahn, J. H., Lee, H. J., Lee, E. K., Yu, H. K., Lee, T. H., Yoon, Y., Kim, S. J. & Kim, J. S., 2011 Apr 1, In : Biological Chemistry. 392, 4, p. 347-356 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2009

cIAP1, cIAP2, and xIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-κB activation

Jin, H. S., Lee, D. H., Kim, D. H. U., Chung, J. H. U., Lee, S. J. U. & Lee, T., 2009 Mar 1, In : Cancer Research. 69, 5, p. 1782-1791 10 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)
2008

Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease

Young, M. L., Park, S. H., Shin, D. I., Hwang, J. Y., Park, B. K., Park, Y. J., Lee, T. H., Chae, H. Z., Jin, B. K., Oh, T. H. & Oh, Y. J., 2008 Apr 11, In : Journal of Biological Chemistry. 283, 15, p. 9986-9998 13 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)
2006

Cell cycle-dependent expression of cIAP2 at G2/M phase contributes to survival during mitotic cell cycle arrest

Jin, H. S. & Lee, T. H., 2006 Oct 15, In : Biochemical Journal. 399, 2, p. 335-342 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas

Hu, S., Du, M. Q., Park, S. M., Alcivar, A., Qu, L., Gupta, S., Tang, J., Baens, M., Ye, H., Lee, T. H., Marynen, P., Riley, J. L. & Yang, X., 2006 Jan 1, In : Journal of Clinical Investigation. 116, 1, p. 174-181 8 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

The interaction of hepatitis B virus X protein and protein phosphatase type 2 Cα and its effect on IL-6

Kim, J. S., Rho, B. Y., Lee, T. H., Lee, J. M., Kim, S. J. & Park, J. H., 2006 Dec 8, In : Biochemical and Biophysical Research Communications. 351, 1, p. 253-258 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2005

Anti-IgM induces up-regulation and tyrosine-phosphorylation of heterogeneous nuclear ribonucleoprotein K proteins (hnRNP K) in a Ramos B cell line

Jeon, H. K., Ahn, J. H., Choe, J., Park, J. H. & Lee, T. H., 2005 May 15, In : Immunology Letters. 98, 2, p. 303-310 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
19 Citations (Scopus)

Role of FLASH in caspase-8-mediated activation of NF-κB: Dominant-negative function of FLASH mutant in NF-κB signaling pathway

Jum, J. I., Chung, C. W., Lee, H. J., Pyo, J. O., Lee, K. N., Kim, N. S., Kim, Y. S., Yoo, H. S., Lee, T. H., Kim, E. & Jung, Y. K., 2005 Jan 20, In : Oncogene. 24, 4, p. 688-696 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

TGF-β inhibits Fas-mediated apoptosis of a follicular dendritic cell line by down-regulating the expression of Fas and caspase-8: Counteracting role of TGF-β on TNF sensitization of Fas-mediated apoptosis

Park, S. M., Kim, S., Choi, J. S., Hur, D. Y., Lee, W. J., Lee, M. S., Choe, J. & Lee, T. H., 2005 May 15, In : Journal of Immunology. 174, 10, p. 6169-6175 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT

Kim, J. H., Park, S. M., Kang, M. R., Oh, S. Y., Lee, T. H., Muller, M. T. & Chung, I. K., 2005 Apr 1, In : Genes and Development. 19, 7, p. 776-781 6 p.

Research output: Contribution to journalArticle

127 Citations (Scopus)
2004
2 Citations (Scopus)

Cisplatin-induced apoptosis in Hep3B cells: Mitochondria-dependent and -independent pathways

Kim, J. S., Lee, J. M., Chwae, Y. J., Kim, Y. H., Lee, J. H., Kim, K., Lee, T. H., Kim, S. J. & Park, J. H., 2004 Apr 15, In : Biochemical Pharmacology. 67, 8, p. 1459-1468 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Mass spectrometric analysis of tumor necrosis factor receptor-associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2

Lee, J. S., Hong, U. S., Lee, T. H., Sungjoo, K. Y. & Yoon, J. B., 2004 Nov 1, In : Proteomics. 4, 11, p. 3376-3382 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Proteome analysis associated with cadmium adaptation in U937 cells. Identification of calbindin-D28k as a secondary cadmium-responsive protein that confers resistance to cadmium-induced apoptosis

Jeon, H. K., Jin, H. S., Lee, D. H., Choi, W. S., Moon, C. K., Oh, Y. J. & Lee, T. H., 2004 Jul 23, In : Journal of Biological Chemistry. 279, 30, p. 31575-31583 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro

Park, S. M., Yoon, J. B. & Lee, T. H., 2004 May 21, In : FEBS Letters. 566, 1-3, p. 151-156 6 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)
2003

Functional effects of TNF-α on a human follicular dendritic cell line: Persistent NF-κB activation and sensitization for Fas-mediated apoptosis

Park, S. M., Park, H. Y. & Lee, T. H., 2003 Oct 15, In : Journal of Immunology. 171, 8, p. 3955-3962 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

IL-4 augments anisomycin-induced p38 activation via Akt pathway in a follicular dendritic cell (FDC)-like line

Lee, H. M., Jin, H. S., Park, J. W., Park, S. M., Jeon, H. K. & Lee, T. H., 2003 Aug 14, In : FEBS Letters. 549, 1-3, p. 110-114 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2002

Soluble Fas ligand-susceptible "memory" cells in mice but not in human: Potential role of soluble Fas ligand in deletion of auto-reactive cells

Kim, S., Kim, J. Y., Lee, T. H., Suk, K., Cha, H. S., Koh, E. M., Yagita, H. & Lee, M. S., 2002 Jul 4, In : Autoimmunity. 35, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2001

Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells

Lee, Z. H., Lee, S. E., Kwack, K., Yeo, W., Lee, T. H., Bae, S. S., Suh, P. G. & Kim, H. H., 2001 Mar 28, In : Journal of Leukocyte Biology. 69, 3, p. 490-496 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Non-apoptotic signaling pathways activated by soluble Fas ligand in serum-starved human fibroblasts: Mitogen-activated protein kinases and NF-κB-dependent gene expression

Ahn, J. H., Park, S. M., Cho, H. S., Lee, M. S., Yoon, J. B., Vilcek, J. & Lee, T. H., 2001 Dec 14, In : Journal of Biological Chemistry. 276, 50, p. 47100-47106 7 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)
2000

Inhibition of autoimmune diabetes by Fas ligand: The paradox is solved

Kim, S., Kim, K. A., Hwang, D. Y., Lee, T. H., Kayagaki, N., Yagita, H. & Lee, M. S., 2000 Mar 15, In : Journal of Immunology. 164, 6, p. 2931-2936 6 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Involvement of two NF-κB binding elements in tumor necrosis factor α-, CD40-, and Epstein-Barr virus latent membrane protein 1-mediated induction of the cellular inhibitor of apoptosis protein 2 gene

Hong, S. Y., Yoon, W. H., Park, J. H., Kang, S. G., Ahn, J. H. & Lee, T. H., 2000 Jun 16, In : Journal of Biological Chemistry. 275, 24, p. 18022-18028 7 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
1999
27 Citations (Scopus)

The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD

Jeong, E. J., Bang, S. H., Lee, T. H., Park, Y. I., Sim, W. S. & Kim, K. S., 1999 Jun 4, In : Journal of Biological Chemistry. 274, 23, p. 16337-16342 6 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
1998

Characterization of an immunosuppressive anti-CD40 ligand monoclonal antibody

Kim, K. M., Min, H. Y., Jung, S. H., Lee, T. H., Kim, J. G. & Kang, C. Y., 1998 Jan 1, In : Hybridoma. 17, 5, p. 463-470 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Enhanced extraction efficiency of recombinant proteins by use of the KNR4-disrupted strains of Saccharomyces cerevisiae

Park, S. M., Song, Y. H., Kim, S. H., Lee, Y. M., Cho, H. S., Kim, J. S., Lee, T. G. & Lee, T. H., 1998 Jan 1, In : Biotechnology Letters. 20, 5, p. 511-514 4 p.

Research output: Contribution to journalArticle

1997

A plasmid vector facilitating gene expression in both yeast and mammalian cells

Lee, T. H., 1997 Jun 1, In : Journal of Microbiology. 35, 2, p. 149-151 3 p.

Research output: Contribution to journalArticle

Codon optimization for high-level expression of human erythropoietin (EPO) in mammalian cells

Kim, C. H., Oh, Y. & Lee, T. H., 1997 Oct 15, In : Gene. 199, 1-2, p. 293-301 9 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Effect of polyamines on cellular differentiation of N. gruberi: Inhibition of translation of tubulin mRNA

Yoo, J. U., Kwon, K. S., Cho, H. I., Kim, D., Chung, I. K., Kim, Y. M., Lee, T. H. & Lee, J. H., 1997 Dec 1, In : Journal of Microbiology. 35, 4, p. 315-322 8 p.

Research output: Contribution to journalArticle

1996

Induction of cell death by myristylated death domain of p55 tnf receptor is not abolished by ipr-tike point mutation

Lee, T. H., Kim, C. H., Song, Y. H., Park, K. & Qh, Y., 1996 Dec 1, In : FASEB Journal. 10, 6, p. A1335

Research output: Contribution to journalArticle

1995

Induction of cell death by myristylated death domain of p55 TNF receptor is not abolished by lpr(cg)-like point mutation in death domain

Kim, C. H., Song, Y. H., Park, K., Oh, Y. & Lee, T. H., 1995 Dec 1, In : Journal of Inflammation. 45, 4, p. 312-322 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

Stanger, B. Z., Leder, P., Lee, T. H., Kim, E. & Seed, B., 1995 May 19, In : Cell. 81, 4, p. 513-523 11 p.

Research output: Contribution to journalArticle

799 Citations (Scopus)
1994

Interferon-β induces metalloproteinase mRNA expression in human fibroblasts. Role of activator protein-1

Sciavolino, P. J., Lee, T. H. & Vilcek, J., 1994 Jan 1, In : Journal of Biological Chemistry. 269, 34, p. 21627-21634 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1

Klampfer, L., Lee, T. H., Hsu, W., Vilček, J. & Chen-Kiang, S., 1994 Oct, In : Molecular and cellular biology. 14, 10, p. 6561-6569 9 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Relationship of TSG-14 protein to the pentraxin family of major acute phase proteins

Lee, G. W., Goodman, A. R., Lee, T. H. & Vilček, J., 1994 Oct 15, In : Journal of Immunology. 153, 8, p. 3700-3707 8 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)
1993

Transcriptional regulation of TSG6, a tumor necrosis factor- and interleukin-1-inducible primary response gene coding for a secreted hyaluronan-binding protein

Lee, T. H., Klampfer, L., Shows, T. B. & Vilcek, J., 1993 Jan 1, In : Journal of Biological Chemistry. 268, 9, p. 6154-6160 7 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins

Lee, G. W., Lee, T. H. & Vilcek, J. T., 1993 Jan 1, In : Journal of Immunology. 150, 5, p. 1804-1812 9 p.

Research output: Contribution to journalArticle

205 Citations (Scopus)

TSG-6: A TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritis

Wisniewski, H. G., Maier, R., Lotz, M., Lee, S., Klampfer, L., Lee, T. H. & Vilcek, J., 1993 Jan 1, In : Journal of Immunology. 151, 11, p. 6593-6601 9 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)
1992
231 Citations (Scopus)

Downregulation of interleukin 8 gene expression in human fibroblasts: Unique mechanism of transcriptional inhibition by interferon

Oliveira, I. C., Sciavolino, P. J., Lee, T. H. & Vilček, J., 1992 Oct 1, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 19, p. 9049-9053 5 p.

Research output: Contribution to journalArticle

159 Citations (Scopus)

Overexpression of metallothionein confers resistance to the cytotoxic effect of TNF with cadmium in MCF-7 breast carcinoma cells

Sciavolino, P. J., Lee, T. H. & Vilcek, J., 1992 Jan 1, In : Lymphokine and Cytokine Research. 11, 5, p. 265-270 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
1990

Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts

Lee, T. H., Lee, G. W., Ziff, E. B. & Vilček, J., 1990 Jan 1, In : Molecular and cellular biology. 10, 5, p. 1982-1988 7 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)
1989

Antiviral Action of TNF in Human Fibroblasts Requires the Presence of Subeffective Concentrations of Classical Interferon‐β

REIS, L. F. L., LEE, T. H., KOHASE, M., ZHANG, Y., LIN, J. X., FUJITA, T., TANIGUCHI, T. & VILČEK, J., 1989 Jun, In : Annals of the New York Academy of Sciences. 557, 1, p. 540-542 3 p.

Research output: Contribution to journalArticle

Tumor necrosis factor acts synergistically with autocrine interferon-β and increases interferon-β mRNA levels in human fibroblasts

Reis, L. F. L., Lee, T. H. & Vilcek, J., 1989 Jan 1, In : Journal of Biological Chemistry. 264, 28, p. 16351-16354 4 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)