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Research Output 1989 2017

  • 3874 Citations
  • 25 h-Index
  • 48 Article
  • 1 Chapter
  • 1 Paper
  • 1 Review article
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Article
2017

Kinetic analysis of de novo centriole assembly in heat-shocked mammalian cells

Baek, I. K., Jang, Y. K., Lee, T. H. & Lee, J., 2017 Jan 1, In : Cytoskeleton. 74, 1, p. 18-28 11 p.

Research output: Contribution to journalArticle

Centrioles
Hot Temperature
Tubulin
Centrosome
Shock
2013
10 Citations (Scopus)

UNC119a bridges the transmission of Fyn signals to RAB11, leading to the completion of cytokinesis

Lee, Y. K., Chung, S., Baek, I. K., Lee, T. H., Paik, S. Y. & Lee, J. H., 2013 Apr 15, In : Cell Cycle. 12, 8, p. 1303-1315 13 p.

Research output: Contribution to journalArticle

Cytokinesis
src-Family Kinases
Signal Transduction
Phosphorylation
Spindle Poles
2011
15 Citations (Scopus)

A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration

Jin, H. S., Park, H. S., Shin, J. H., Kim, D. H., Jun, S. H., Lee, C. J. & Lee, T. H., 2011 Sep 2, In : Biochemical and Biophysical Research Communications. 412, 3, p. 454-459 6 p.

Research output: Contribution to journalArticle

Inhibitor of Apoptosis Proteins
TNF Receptor-Associated Factor 2
Apoptosis
Protein Binding
Carrier Proteins
4 Citations (Scopus)

Antiangiogenic kringles derived from human plasminogen and apolipoprotein(a) inhibit fibrinolysis through a mechanism that requires a functional lysine-binding site

Ahn, J. H., Lee, H. J., Lee, E. K., Yu, H. K., Lee, T. H., Yoon, Y., Kim, S. J. & Kim, J. S., 2011 Apr 1, In : Biological Chemistry. 392, 4, p. 347-356 10 p.

Research output: Contribution to journalArticle

Kringles
Apoprotein(a)
Plasminogen
Fibrinolysis
Lysine
2009
76 Citations (Scopus)

cIAP1, cIAP2, and xIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-κB activation

Jin, H. S., Lee, D. H., Kim, D. H. U., Chung, J. H. U., Lee, S. J. U. & Lee, T., 2009 Mar 1, In : Cancer Research. 69, 5, p. 1782-1791 10 p.

Research output: Contribution to journalArticle

Ubiquitination
DNA Damage
Phosphotransferases
Inhibitor of Apoptosis Proteins
MAP Kinase Signaling System
2008
78 Citations (Scopus)

Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease

Young, M. L., Park, S. H., Shin, D. I., Hwang, J. Y., Park, B. K., Park, Y. J., Lee, T. H., Chae, H. Z., Jin, B. K., Oh, T. H. & Oh, Y. J., 2008 Apr 11, In : Journal of Biological Chemistry. 283, 15, p. 9986-9998 13 p.

Research output: Contribution to journalArticle

Peroxiredoxins
Oxidopamine
Parkinsonian Disorders
Theoretical Models
Pharmaceutical Preparations
2006
19 Citations (Scopus)

Cell cycle-dependent expression of cIAP2 at G2/M phase contributes to survival during mitotic cell cycle arrest

Jin, H. S. & Lee, T. H., 2006 Oct 15, In : Biochemical Journal. 399, 2, p. 335-342 8 p.

Research output: Contribution to journalArticle

Inhibitor of Apoptosis Proteins
G2 Phase
Cell Cycle Checkpoints
Cell Division
Cell Cycle
80 Citations (Scopus)

cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas

Hu, S., Du, M. Q., Park, S. M., Alcivar, A., Qu, L., Gupta, S., Tang, J., Baens, M., Ye, H., Lee, T. H., Marynen, P., Riley, J. L. & Yang, X., 2006 Jan 1, In : Journal of Clinical Investigation. 116, 1, p. 174-181 8 p.

Research output: Contribution to journalArticle

Marginal Zone B-Cell Lymphoma
Ubiquitin-Protein Ligases
Antigen Receptors
Genetic Translocation
Proteins
16 Citations (Scopus)

The interaction of hepatitis B virus X protein and protein phosphatase type 2 Cα and its effect on IL-6

Kim, J. S., Rho, B. Y., Lee, T. H., Lee, J. M., Kim, S. J. & Park, J. H., 2006 Dec 8, In : Biochemical and Biophysical Research Communications. 351, 1, p. 253-258 6 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Phosphoprotein Phosphatases
Interleukin-6
Proteins
Enzyme activity
2005
8 Citations (Scopus)

Anti-IgM induces up-regulation and tyrosine-phosphorylation of heterogeneous nuclear ribonucleoprotein K proteins (hnRNP K) in a Ramos B cell line

Jeon, H. K., Ahn, J. H., Choe, J., Park, J. H. & Lee, T. H., 2005 May 15, In : Immunology Letters. 98, 2, p. 303-310 8 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein K
Tyrosine
B-Lymphocytes
Up-Regulation
Phosphorylation
19 Citations (Scopus)
Transcriptional Activation
Marginal Zone B-Cell Lymphoma
Fusion reactions
Genes
Chemical activation
22 Citations (Scopus)

Role of FLASH in caspase-8-mediated activation of NF-κB: Dominant-negative function of FLASH mutant in NF-κB signaling pathway

Jum, J. I., Chung, C. W., Lee, H. J., Pyo, J. O., Lee, K. N., Kim, N. S., Kim, Y. S., Yoo, H. S., Lee, T. H., Kim, E. & Jung, Y. K., 2005 Jan 20, In : Oncogene. 24, 4, p. 688-696 9 p.

Research output: Contribution to journalArticle

Caspase 8
Mutant Proteins
Proteins
Tumor Necrosis Factor-alpha
Caspases
14 Citations (Scopus)

TGF-β inhibits Fas-mediated apoptosis of a follicular dendritic cell line by down-regulating the expression of Fas and caspase-8: Counteracting role of TGF-β on TNF sensitization of Fas-mediated apoptosis

Park, S. M., Kim, S., Choi, J. S., Hur, D. Y., Lee, W. J., Lee, M. S., Choe, J. & Lee, T. H., 2005 May 15, In : Journal of Immunology. 174, 10, p. 6169-6175 7 p.

Research output: Contribution to journalArticle

Follicular Dendritic Cells
Caspase 8
Germinal Center
Apoptosis
Cell Line
122 Citations (Scopus)

Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT

Kim, J. H., Park, S. M., Kang, M. R., Oh, S. Y., Lee, T. H., Muller, M. T. & Chung, I. K., 2005 Apr 1, In : Genes and Development. 19, 7, p. 776-781 6 p.

Research output: Contribution to journalArticle

Telomere Homeostasis
Telomerase
Ligases
Ubiquitin
Proteolysis
2004
2 Citations (Scopus)
Pemphigus
Complementary DNA
Monoclonal Antibodies
Light
Antigens
36 Citations (Scopus)

Cisplatin-induced apoptosis in Hep3B cells: Mitochondria-dependent and -independent pathways

Kim, J. S., Lee, J. M., Chwae, Y. J., Kim, Y. H., Lee, J. H., Kim, K., Lee, T. H., Kim, S. J. & Park, J. H., 2004 Apr 15, In : Biochemical Pharmacology. 67, 8, p. 1459-1468 10 p.

Research output: Contribution to journalArticle

Mitochondria
Cisplatin
Apoptosis
Caspases
Assays
23 Citations (Scopus)

Mass spectrometric analysis of tumor necrosis factor receptor-associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2

Lee, J. S., Hong, U. S., Lee, T. H., Sungjoo, K. Y. & Yoon, J. B., 2004 Nov 1, In : Proteomics. 4, 11, p. 3376-3382 7 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 1
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Ubiquitination
Apoptosis
R388
11 Citations (Scopus)

Proteome analysis associated with cadmium adaptation in U937 cells. Identification of calbindin-D28k as a secondary cadmium-responsive protein that confers resistance to cadmium-induced apoptosis

Jeon, H. K., Jin, H. S., Lee, D. H., Choi, W. S., Moon, C. K., Oh, Y. J. & Lee, T. H., 2004 Jul 23, In : Journal of Biological Chemistry. 279, 30, p. 31575-31583 9 p.

Research output: Contribution to journalArticle

Calbindin 1
U937 Cells
Proteome
Cadmium
Apoptosis
94 Citations (Scopus)

Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro

Park, S. M., Yoon, J. B. & Lee, T. H., 2004 May 21, In : FEBS Letters. 566, 1-3, p. 151-156 6 p.

Research output: Contribution to journalArticle

Receptor-Interacting Protein Serine-Threonine Kinases
Inhibitor of Apoptosis Proteins
Tumor Necrosis Factor Receptors
Ubiquitination
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
2003
16 Citations (Scopus)

Functional effects of TNF-α on a human follicular dendritic cell line: Persistent NF-κB activation and sensitization for Fas-mediated apoptosis

Park, S. M., Park, H. Y. & Lee, T. H., 2003 Oct 15, In : Journal of Immunology. 171, 8, p. 3955-3962 8 p.

Research output: Contribution to journalArticle

Follicular Dendritic Cells
Germinal Center
Apoptosis
Cell Line
Inhibitor of Apoptosis Proteins
12 Citations (Scopus)

IL-4 augments anisomycin-induced p38 activation via Akt pathway in a follicular dendritic cell (FDC)-like line

Lee, H. M., Jin, H. S., Park, J. W., Park, S. M., Jeon, H. K. & Lee, T. H., 2003 Aug 14, In : FEBS Letters. 549, 1-3, p. 110-114 5 p.

Research output: Contribution to journalArticle

Anisomycin
Follicular Dendritic Cells
Interleukin-4
Chemical activation
Phosphatidylinositol 3-Kinases
2002
6 Citations (Scopus)

Soluble Fas ligand-susceptible "memory" cells in mice but not in human: Potential role of soluble Fas ligand in deletion of auto-reactive cells

Kim, S., Kim, J. Y., Lee, T. H., Suk, K., Cha, H. S., Koh, E. M., Yagita, H. & Lee, M. S., 2002 Jul 4, In : Autoimmunity. 35, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Lymphocytes
Propidium
Systemic Lupus Erythematosus
2001
15 Citations (Scopus)

Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells

Lee, Z. H., Lee, S. E., Kwack, K., Yeo, W., Lee, T. H., Bae, S. S., Suh, P. G. & Kim, H. H., 2001 Mar 28, In : Journal of Leukocyte Biology. 69, 3, p. 490-496 7 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 3
Jurkat Cells
Caspases
T-Lymphocytes
Cell Death
81 Citations (Scopus)

Non-apoptotic signaling pathways activated by soluble Fas ligand in serum-starved human fibroblasts: Mitogen-activated protein kinases and NF-κB-dependent gene expression

Ahn, J. H., Park, S. M., Cho, H. S., Lee, M. S., Yoon, J. B., Vilcek, J. & Lee, T. H., 2001 Dec 14, In : Journal of Biological Chemistry. 276, 50, p. 47100-47106 7 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Fas Ligand Protein
Fibroblasts
Mitogen-Activated Protein Kinases
Gene expression
2000
84 Citations (Scopus)

Inhibition of autoimmune diabetes by Fas ligand: The paradox is solved

Kim, S., Kim, K. A., Hwang, D. Y., Lee, T. H., Kayagaki, N., Yagita, H. & Lee, M. S., 2000 Mar 15, In : Journal of Immunology. 164, 6, p. 2931-2936 6 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Type 1 Diabetes Mellitus
Inbred NOD Mouse
Lymphocytes
Apoptosis
105 Citations (Scopus)

Involvement of two NF-κB binding elements in tumor necrosis factor α-, CD40-, and Epstein-Barr virus latent membrane protein 1-mediated induction of the cellular inhibitor of apoptosis protein 2 gene

Hong, S. Y., Yoon, W. H., Park, J. H., Kang, S. G., Ahn, J. H. & Lee, T. H., 2000 Jun 16, In : Journal of Biological Chemistry. 275, 24, p. 18022-18028 7 p.

Research output: Contribution to journalArticle

Inhibitor of Apoptosis Proteins
Tumor Necrosis Factor-alpha
Genes
5' Flanking Region
Transcription
1999
27 Citations (Scopus)
Follicular Dendritic Cells
CD40 Ligand
Mitogen-Activated Protein Kinases
Transcriptional Activation
Germinal Center
96 Citations (Scopus)

The solution structure of FADD death domain. Structural basis of death domain interactions of Fas and FADD

Jeong, E. J., Bang, S. H., Lee, T. H., Park, Y. I., Sim, W. S. & Kim, K. S., 1999 Jun 4, In : Journal of Biological Chemistry. 274, 23, p. 16337-16342 6 p.

Research output: Contribution to journalArticle

Fas-Associated Death Domain Protein
Apoptosis
Signal transduction
Mutagenesis
Site-Directed Mutagenesis
1998
3 Citations (Scopus)

Characterization of an immunosuppressive anti-CD40 ligand monoclonal antibody

Kim, K. M., Min, H. Y., Jung, S. H., Lee, T. H., Kim, J. G. & Kang, C. Y., 1998 Jan 1, In : Hybridoma. 17, 5, p. 463-470 8 p.

Research output: Contribution to journalArticle

CD40 Ligand
Immunosuppressive Agents
Monoclonal Antibodies
Severe Combined Immunodeficiency
B-Lymphocytes

Enhanced extraction efficiency of recombinant proteins by use of the KNR4-disrupted strains of Saccharomyces cerevisiae

Park, S. M., Song, Y. H., Kim, S. H., Lee, Y. M., Cho, H. S., Kim, J. S., Lee, T. G. & Lee, T. H., 1998 Jan 1, In : Biotechnology Letters. 20, 5, p. 511-514 4 p.

Research output: Contribution to journalArticle

Recombinant proteins
Recombinant Proteins
Yeast
Cell Wall
Saccharomyces cerevisiae
1997

A plasmid vector facilitating gene expression in both yeast and mammalian cells

Lee, T. H., 1997 Jun 1, In : Journal of Microbiology. 35, 2, p. 149-151 3 p.

Research output: Contribution to journalArticle

Plasmids
Yeasts
Gene Expression
Cytomegalovirus
Galactosidases
111 Citations (Scopus)

Codon optimization for high-level expression of human erythropoietin (EPO) in mammalian cells

Kim, C. H., Oh, Y. & Lee, T. H., 1997 Oct 15, In : Gene. 199, 1-2, p. 293-301 9 p.

Research output: Contribution to journalArticle

Erythropoietin
Codon
Genes
Yeasts
Protein Sorting Signals

Effect of polyamines on cellular differentiation of N. gruberi: Inhibition of translation of tubulin mRNA

Yoo, J. U., Kwon, K. S., Cho, H. I., Kim, D., Chung, I. K., Kim, Y. M., Lee, T. H. & Lee, J. H., 1997 Dec 1, In : Journal of Microbiology. 35, 4, p. 315-322 8 p.

Research output: Contribution to journalArticle

Spermine
Polyamines
Protein Biosynthesis
Tubulin
Naegleria
1996

Induction of cell death by myristylated death domain of p55 tnf receptor is not abolished by ipr-tike point mutation

Lee, T. H., Kim, C. H., Song, Y. H., Park, K. & Qh, Y., 1996 Dec 1, In : FASEB Journal. 10, 6, p. A1335

Research output: Contribution to journalArticle

Cell death
Point Mutation
Gene expression
Cell Death
Gene Expression
1995
13 Citations (Scopus)

Induction of cell death by myristylated death domain of p55 TNF receptor is not abolished by lpr(cg)-like point mutation in death domain

Kim, C. H., Song, Y. H., Park, K., Oh, Y. & Lee, T. H., 1995 Dec 1, In : Journal of Inflammation. 45, 4, p. 312-322 11 p.

Research output: Contribution to journalArticle

Receptors, Tumor Necrosis Factor, Type I
Point Mutation
Cell Death
Gene Expression
Luciferases
788 Citations (Scopus)

RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

Stanger, B. Z., Leder, P., Lee, T. H., Kim, E. & Seed, B., 1995 May 19, In : Cell. 81, 4, p. 513-523 11 p.

Research output: Contribution to journalArticle

Cell death
Yeast
Cause of Death
Cell Death
Yeasts
1994
43 Citations (Scopus)

Interferon-β induces metalloproteinase mRNA expression in human fibroblasts. Role of activator protein-1

Sciavolino, P. J., Lee, T. H. & Vilcek, J., 1994 Jan 1, In : Journal of Biological Chemistry. 269, 34, p. 21627-21634 8 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Metalloproteases
Fibroblasts
Interferons
Tumor Necrosis Factor-alpha
66 Citations (Scopus)

NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1

Klampfer, L., Lee, T. H., Hsu, W., Vilček, J. & Chen-Kiang, S., 1994 Oct, In : Molecular and Cellular Biology. 14, 10, p. 6561-6569 9 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-beta
Transcription Factor AP-1
Interleukin-1
Tumor Necrosis Factor-alpha
Genes
71 Citations (Scopus)

Relationship of TSG-14 protein to the pentraxin family of major acute phase proteins

Lee, G. W., Goodman, A. R., Lee, T. H. & Vilček, J., 1994 Oct 15, In : Journal of Immunology. 153, 8, p. 3700-3707 8 p.

Research output: Contribution to journalArticle

Acute-Phase Proteins
Interleukin-1
C-Reactive Protein
Proteins
Dexamethasone
1993
51 Citations (Scopus)

Transcriptional regulation of TSG6, a tumor necrosis factor- and interleukin-1-inducible primary response gene coding for a secreted hyaluronan-binding protein

Lee, T. H., Klampfer, L., Shows, T. B. & Vilcek, J., 1993 Jan 1, In : Journal of Biological Chemistry. 268, 9, p. 6154-6160 7 p.

Research output: Contribution to journalArticle

CD44 Antigens
Interleukin-1
Tumor Necrosis Factor-alpha
Genes
Interferon Regulatory Factor-2
200 Citations (Scopus)

TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins

Lee, G. W., Lee, T. H. & Vilcek, J. T., 1993 Jan 1, In : Journal of Immunology. 150, 5, p. 1804-1812 9 p.

Research output: Contribution to journalArticle

Acute-Phase Proteins
Interleukin-1
Tumor Necrosis Factor-alpha
Proteins
Messenger RNA
115 Citations (Scopus)

TSG-6: A TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritis

Wisniewski, H. G., Maier, R., Lotz, M., Lee, S., Klampfer, L., Lee, T. H. & Vilcek, J., 1993 Jan 1, In : Journal of Immunology. 151, 11, p. 6593-6601 9 p.

Research output: Contribution to journalArticle

Interleukin-1
Arthritis
Glycoproteins
Synovial Fluid
Genes
1992
225 Citations (Scopus)
Carrier Proteins
Tumor Necrosis Factor-alpha
Proteins
Complementary DNA
Fibroblasts
157 Citations (Scopus)

Downregulation of interleukin 8 gene expression in human fibroblasts: Unique mechanism of transcriptional inhibition by interferon

Oliveira, I. C., Sciavolino, P. J., Lee, T. H. & Vilček, J., 1992 Oct 1, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 19, p. 9049-9053 5 p.

Research output: Contribution to journalArticle

Interleukin-8
Interferons
Down-Regulation
Fibroblasts
Gene Expression
28 Citations (Scopus)

Overexpression of metallothionein confers resistance to the cytotoxic effect of TNF with cadmium in MCF-7 breast carcinoma cells

Sciavolino, P. J., Lee, T. H. & Vilcek, J., 1992 Jan 1, In : Lymphokine and Cytokine Research. 11, 5, p. 265-270 6 p.

Research output: Contribution to journalArticle

Metallothionein
Cadmium
Tumor Necrosis Factor-alpha
Breast Neoplasms
Cadmium Chloride
1990
119 Citations (Scopus)

Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts

Lee, T. H., Lee, G. W., Ziff, E. B. & Vilček, J., 1990 Jan 1, In : Molecular and cellular biology. 10, 5, p. 1982-1988 7 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor-alpha
Fibroblasts
Genes
Complementary DNA
Matrix Metalloproteinase 3
1989

Antiviral Action of TNF in Human Fibroblasts Requires the Presence of Subeffective Concentrations of Classical Interferon‐β

REIS, L. F. L., Lee, T. H., KOHASE, M., ZHANG, Y., LIN, J. X., FUJITA, T., TANIGUCHI, T. & VILČEK, J., 1989 Jan 1, In : Annals of the New York Academy of Sciences. 557, 1, p. 540-542 3 p.

Research output: Contribution to journalArticle

Interferon-beta
Fibroblasts
Antiviral Agents
51 Citations (Scopus)

Tumor necrosis factor acts synergistically with autocrine interferon-β and increases interferon-β mRNA levels in human fibroblasts

Reis, L. F. L., Lee, T. H. & Vilcek, J., 1989 Jan 1, In : Journal of Biological Chemistry. 264, 28, p. 16351-16354 4 p.

Research output: Contribution to journalArticle

Fibroblasts
Interferons
Tumor Necrosis Factor-alpha
Messenger RNA
Encephalomyocarditis virus