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1989 …2019
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Research Output 1989 2019

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2019

Filbertone ameliorates adiposity in mice fed a high-fat diet via activation of cAMP signaling

Moon, Y., Tong, T., Kang, W. & Park, T., 2019 Aug 1, In : Nutrients. 11, 8, 1749.

Research output: Contribution to journalArticle

Open Access
Adiposity
cyclic AMP
adiposity
High Fat Diet
high fat diet
2 Citations (Scopus)

α-Cedrene protects rodents from high-fat diet-induced adiposity via adenylyl cyclase 3

Tong, T., Yu, R. & Park, T., 2019 Jan 1, In : International Journal of Obesity. 43, 1, p. 202-216 15 p.

Research output: Contribution to journalArticle

Adiposity
High Fat Diet
Adenylyl Cyclases
Rodentia
Obesity
1 Citation (Scopus)

α-Ionone attenuates high-fat diet-induced skeletal muscle wasting in mice: Via activation of cAMP signaling

Tong, T., Kim, M. & Park, T., 2019 Feb 1, In : Food and Function. 10, 2, p. 1167-1178 12 p.

Research output: Contribution to journalArticle

Norisoprenoids
norisoprenoids
High Fat Diet
high fat diet
skeletal muscle

α-ionone protects against UVB-induced photoaging in human dermal fibroblasts

Tong, T., Park, J., Moon, Y., Kang, W. & Park, T., 2019 Jan 1, In : Molecules. 24, 9, 1804.

Research output: Contribution to journalArticle

Open Access
Norisoprenoids
fibroblasts
Fibroblasts
collagens
Skin
2018
1 Citation (Scopus)

Regulation of adipogenesis and thermogenesis through mouse olfactory receptor 23 stimulated by α-cedrene in 3T3-L1 cells

Tong, T., Park, J., Moon, C. & Park, T., 2018 Nov 16, In : Nutrients. 10, 11, 1781.

Research output: Contribution to journalArticle

Odorant Receptors
3T3-L1 Cells
Adipogenesis
olfactory receptors
Thermogenesis
3 Citations (Scopus)

α-Cedrene, a Newly Identified Ligand of MOR23, Increases Skeletal Muscle Mass and Strength

Tong, T., Kim, M. & Park, T., 2018 Aug 1, In : Molecular Nutrition and Food Research. 62, 15, 1800173.

Research output: Contribution to journalArticle

Odorant Receptors
olfactory receptors
Muscle Strength
skeletal muscle
Skeletal Muscle
2017

Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle

Le, N. H., Kim, C. S., Tu, T. H., Kim, B. S., Park, T., Park, J. H. Y., Goto, T., Kawada, T., Ha, T. Y. & Yu, R., 2017 May 11, In : Journal of Inflammation (United Kingdom). 14, 1, 9.

Research output: Contribution to journalArticle

Muscle
Skeletal Muscle
Obesity
Muscular Atrophy
Inflammation
3 Citations (Scopus)
adenosine monophosphate
lipoproteins
Artemisia
Lipoproteins
diets
8 Citations (Scopus)

Olfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP-PKA pathway

Tong, T., Ryu, S. E., Min, Y., De March, C. A., Bushdid, C., Golebiowski, J., Moon, C. & Park, T., 2017 Dec 1, In : Scientific reports. 7, 1, 9471.

Research output: Contribution to journalArticle

Odorant Receptors
Hepatocytes
Liver
RNA Interference
Lipids
adenylate kinase
Adenylate Kinase
Adiposity
adiposity
High Fat Diet
18 Citations (Scopus)

Quercetin protects obesity-induced hypothalamic inflammation by reducing microglia-mediated inflammatory responses via HO-1 induction

Yang, J., Kim, C. S., Tu, T. H., Kim, M. S., Goto, T., Kawada, T., Choi, M. S., Park, T., Sung, M. K., Yun, J. W., Choe, S. Y., Lee, J. H., Joe, Y., Choi, H. S., Back, S. H., Chung, H. T. & Yu, R., 2017 Jul 1, In : Nutrients. 9, 7, 650.

Research output: Contribution to journalArticle

Quercetin
neuroglia
Microglia
quercetin
obesity
6 Citations (Scopus)

Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: Potential involvement of SIRT1-mediated signaling cascades in the liver

Yoo, A., Narayan, V. P., Hong, E. Y., Whang, W. K. & Park, T., 2017 Dec 1, In : Scientific Reports. 7, 1, 2251.

Research output: Contribution to journalArticle

Sirtuin 1
High Fat Diet
Liver
Down-Regulation
scopolin
2016
18 Citations (Scopus)

Adenylyl cyclase 3 haploinsufficiency confers susceptibility to diet-induced obesity and insulin resistance in mice

Tong, T., Shen, Y., Lee, H. W., Yu, R. & Park, T., 2016 Sep 28, In : Scientific reports. 6, 34179.

Research output: Contribution to journalArticle

Haploinsufficiency
Adenylyl Cyclases
Insulin Resistance
Obesity
Diet
2 Citations (Scopus)

Enzymatically modified isoquercitrin attenuates high-fat diet-induced obesity

Min, Y. & Park, T., 2016 Apr 1, In : Journal of the Korean Society of Food Science and Nutrition. 45, 4, p. 474-483 10 p.

Research output: Contribution to journalArticle

isoquercitrin
High Fat Diet
high fat diet
obesity
Obesity
8 Citations (Scopus)

Increased expression of FGF1-mediated signaling molecules in adipose tissue of obese mice

Choi, Y., Jang, S., Choi, M. S., Ryoo, Z. Y. & Park, T., 2016 Jun 1, In : Journal of Physiology and Biochemistry. 72, 2, p. 157-167 11 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Obese Mice
Nutrition
Adipose Tissue
Receptor, Fibroblast Growth Factor, Type 1
9 Citations (Scopus)

The Soy Peptide Phe-Leu-Val Reduces TNFα-Induced Inflammatory Response and Insulin Resistance in Adipocytes

Kwak, S. J., Kim, C. S., Choi, M. S., Park, T., Sung, M. K., Yun, J. W., Yoo, H., Mine, Y. & Yu, R., 2016 Jul 1, In : Journal of medicinal food. 19, 7, p. 678-685 8 p.

Research output: Contribution to journalArticle

Adipocytes
Insulin Resistance
Tumor Necrosis Factor-alpha
Peptides
Obesity
10 Citations (Scopus)

Whole‑transcriptome analysis of mouse adipose tissue in response to short‑term caloric restriction

Kim, S. S., Choi, K. M., Kim, S., Park, T., Cho, I. C., Lee, J. W. & Lee, C. K., 2016 Apr 1, In : Molecular Genetics and Genomics. 291, 2, p. 831-847 17 p.

Research output: Contribution to journalArticle

Caloric Restriction
Adipose Tissue
Genes
Somatomedins
Epidermal Growth Factor
2015
8 Citations (Scopus)

4-1BBL signaling promotes cell proliferation through reprogramming of glucose metabolism in monocytes/macrophages

Tu, T. H., Kim, C. S., Nam-Goong, I. S., Nam, C. W., Kim, Y. I., Goto, T., Kawada, T., Park, T., Yoon Park, J. H., Ryoo, Z. Y., Park, J. W., Choi, H. S. & Yu, R., 2015 Apr 1, In : FEBS Journal. 282, 8, p. 1468-1480 13 p.

Research output: Contribution to journalArticle

Macrophages
Cell proliferation
Metabolism
Monocytes
Cell Proliferation
43 Citations (Scopus)

Downregulation of microRNA-451 in non-alcoholic steatohepatitis inhibits fatty acid-induced proinflammatory cytokine production through the AMPK/AKT pathway

Hur, W., Lee, J. H., Kim, S. W., Kim, J. H., Bae, S. H., Kim, M., Hwang, D., Kim, Y. S., Park, T., Um, S. J., Song, B. J. & Yoon, S. K., 2015 May 17, In : International Journal of Biochemistry and Cell Biology. 64, p. 265-276 12 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Palmitates
Fatty Liver
MicroRNAs
Liver
1 Citation (Scopus)

Hyperproduction of IL-6 caused by aberrant TDP-43 overexpression in high-fat diet-induced obese mice

Lee, S., Lee, T. A., Song, S. J., Park, T. & Park, B., 2015 Jul 3, In : FEBS Letters. 589, 15, p. 1825-1831 7 p., 37196.

Research output: Contribution to journalArticle

Obese Mice
High Fat Diet
Nutrition
Interleukin-6
Fats
9 Citations (Scopus)

Identification of a subnuclear body involved in sequence-specific cytokine RNA processing

Lee, S., Lee, T. A., Lee, E., Kang, S., Park, A., Kim, S. W., Park, H., Yoon, J. H., Ha, S-J., Park, T., Lee, J. S., Cheon, J. & Park, B., 2015 Jan 5, In : Nature Communications. 6, 6791.

Research output: Contribution to journalArticle

interleukins
splicing
compartments
Interleukin-6
Interleukin-10
10 Citations (Scopus)

IL-7 receptor deletion ameliorates diet-induced obesity and insulin resistance in mice

Lee, M., Song, S. J., Choi, M. S., Yu, R. & Park, T., 2015 Oct 24, In : Diabetologia. 58, 10, p. 2361-2370 10 p.

Research output: Contribution to journalArticle

Interleukin-7 Receptors
Insulin Resistance
White Adipose Tissue
Obesity
Diet
62 Citations (Scopus)

Luteolin attenuates hepatic steatosis and insulin resistance through the interplay between the liver and adipose tissue in mice with diet-induced obesity

Kwon, E. Y., Jung, U. J., Park, T., Yun, J. W. & Choi, M. S., 2015 May 1, In : Diabetes. 64, 5, p. 1658-1669 12 p.

Research output: Contribution to journalArticle

Luteolin
Insulin Resistance
Adipose Tissue
Obesity
Diet
11 Citations (Scopus)

Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats

Mukherjee, R., Kim, S. W., Park, T., Choi, M. S. & Yun, J. W., 2015 Sep 10, In : International Journal of Obesity. 39, 9, p. 1349-1358 10 p.

Research output: Contribution to journalArticle

Galectin 1
Weight Gain
Body Weight
Diet
High Fat Diet
11 Citations (Scopus)

Topical application of oleuropein induces anagen hair growth in telogen mouse skin

Tong, T., Kim, N. & Park, T., 2015 Jun 10, In : PloS one. 10, 6, e0129578.

Research output: Contribution to journalArticle

oleuropein
topical application
Catenins
skin (animal)
Hair
2014
40 Citations (Scopus)
Coffee
Insulin Resistance
Obesity
Diet
Adipogenesis
7 Citations (Scopus)

Dietary camphene attenuates hepatic steatosis and insulin resistance in mice

Kim, S., Choi, Y., Choi, S., Choi, Y. & Park, T., 2014 Feb 1, In : Obesity. 22, 2, p. 408-417 10 p.

Research output: Contribution to journalArticle

Insulin Resistance
High Fat Diet
Liver
Adiponectin
AMP-Activated Protein Kinases
7 Citations (Scopus)

Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters

Tu, T. H., Kim, C. S., Kang, J. H., Nam-Goong, I. S., Nam, C. W., Kim, E. S., Kim, Y. I., Choi, J. I., Kawada, T., Goto, T., Park, T., Yoon Park, J. H., Choi, M. S. & Yu, R., 2014 Jan 1, In : International Journal of Obesity. 38, 8, p. 1075-1082 8 p.

Research output: Contribution to journalArticle

Adipose Tissue
Inflammation
Obesity
Proteins
Body Mass Index
20 Citations (Scopus)

Oleuropein attenuates visceral adiposity in high-fat diet-induced obese mice through the modulation of WNT10b- and galanin-mediated signalings

Kuem, N., Song, S. J., Yu, R., Yun, J. W. & Park, T., 2014 Jan 1, In : Molecular Nutrition and Food Research. 58, 11, p. 2166-2176 11 p.

Research output: Contribution to journalArticle

Galanin
oleuropein
Obese Mice
Adiposity
adiposity
26 Citations (Scopus)

Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice

Kim, S. W., Hur, W., Li, T. Z., Lee, Y. K., Choi, J. E., Hong, S. W., Lyoo, K. S., You, C. R., Jung, E. S., Jung, C. K., Park, T., Um, S. J. & Yoon, S. K., 2014 Jan 1, In : Experimental and Molecular Medicine. 46, 4, e92.

Research output: Contribution to journalArticle

High Fat Diet
Fatty Liver
Nutrition
Fibrosis
Fats
41 Citations (Scopus)
Adipogenesis
Thermogenesis
High Fat Diet
Olea
Obesity
3 Citations (Scopus)

Over-expression of Roquin aggravates T cell mediated hepatitis in transgenic mice using T cell specific promoter

Ji, Y. R., Kim, H. J., Yu, D. H., Bae, K. B., Park, S. J., Park, S. J., Jang, W. Y., Kang, M. C., Jeong, J., Sung, Y. H., Choi, M., Park, T., Park, T., Yun, J. W., Lee, H. S., Lee, S., Kim, M. O. & Ryoo, Z. Y., 2014 Sep 26, In : Biochemical and Biophysical Research Communications. 452, 3, p. 822-827 6 p.

Research output: Contribution to journalArticle

T-cells
Liver
Transgenic Mice
Hepatitis
Concanavalin A
8 Citations (Scopus)

Piperonal prevents high-fat diet-induced hepatic steatosis and insulin resistance in mice via activation of adiponectin/AMPK pathway

Li, X., Choi, Y., Yanakawa, Y. & Park, T., 2014 Jan 1, In : International Journal of Obesity. 38, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Adiponectin
High Fat Diet
Insulin Resistance
Liver
40 Citations (Scopus)

Quercetin protects against obesity-induced skeletal muscle inflammation and atrophy

Le, N. H., Kim, C. S., Park, T., Park, J. H. Y., Sung, M. K., Lee, D. G., Hong, S. M., Choe, S. Y., Goto, T., Kawada, T. & Yu, R., 2014 Dec 28, In : Mediators of Inflammation. 2014, 834294.

Research output: Contribution to journalArticle

Muscular Atrophy
Quercetin
Skeletal Muscle
Obesity
High Fat Diet
18 Citations (Scopus)

Quercetin suppresses MIP-1α-induced adipose inflammation by downregulating its receptors CCR1/CCR5 and inhibiting inflammatory signaling

Noh, H. J., Kim, C. S., Kang, J. H., Park, J. Y., Choe, S. Y., Hong, S. M., Yoo, H., Park, T. & Yu, R., 2014 May 1, In : Journal of medicinal food. 17, 5, p. 550-557 8 p.

Research output: Contribution to journalArticle

CCR1 Receptors
CCR5 Receptors
Macrophage Inflammatory Proteins
Quercetin
Down-Regulation
18 Citations (Scopus)

The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity

Choi, O. M., Cho, Y. H., Choi, S., Lee, S. H., Seo, S. H., Kim, H. Y., Han, G., Min, D. S., Park, T. & Choi, K-Y., 2014 Jan 1, In : International Journal of Obesity. 38, 8, p. 1044-1052 9 p.

Research output: Contribution to journalArticle

Catenins
Oximes
Adipocytes
Obesity
High Fat Diet
2013
11 Citations (Scopus)
Artemisia
Adipogenesis
High Fat Diet
Obesity
Gene Expression
9 Citations (Scopus)

Blockade of 4-1BB and 4-1BBL interaction reduces obesity-induced skeletal muscle inflammation

Le, N. H., Kim, C. S., Tu, T. H., Choi, H. S., Kim, B. S., Kawada, T., Goto, T., Park, T., Yoon Park, J. H. & Yu, R., 2013 Dec 1, In : Mediators of Inflammation. 2013, 865159.

Research output: Contribution to journalArticle

4-1BB Ligand
Skeletal Muscle
Obesity
Inflammation
Macrophages
27 Citations (Scopus)
AMP-Activated Protein Kinases
High Fat Diet
Liver
Phosphorylation
Ribosomal Protein S6 Kinases
12 Citations (Scopus)

Indole-3-carbinol directly targets SIRT1 to inhibit adipocyte differentiation

Choi, Y., Um, S. J. & Park, T., 2013 Jun 1, In : International Journal of Obesity. 37, 6, p. 881-884 4 p.

Research output: Contribution to journalArticle

Adipocytes
3T3-L1 Cells
Brassica
Sirtuin 1
indole-3-carbinol
15 Citations (Scopus)
Smell
Neoplasm Genes
High Fat Diet
high fat diet
Nutrition
2 Citations (Scopus)

Inhibitory effect of yellow myrobalan (Terminalia chebula) extract on fibrosis induced by carbon tetrachloride in rat liver

Koo, Y. C., Hong, C. O., Nam, M. H., Kim, J. H., Yang, S. Y., Won, N. H., Park, T. S. & Lee, K. W., 2013 Jun 1, In : Food Science and Biotechnology. 22, 3, p. 871-880 10 p.

Research output: Contribution to journalArticle

Terminalia chebula
Terminalia
carbon tetrachloride
Carbon Tetrachloride
fibrosis
16 Citations (Scopus)

Involvement of SIRT1-AMPK signaling in the protective action of indole-3-carbinol against hepatic steatosis in mice fed a high-fat diet

Choi, Y., Yanagawa, Y., Kim, S. & Park, T., 2013 Jul 1, In : Journal of Nutritional Biochemistry. 24, 7, p. 1393-1400 8 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
High Fat Diet
Nutrition
Fats
Liver
47 Citations (Scopus)

Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice

Choi, S., Choi, Y., Choi, Y., Kim, S., Jang, J. & Park, T., 2013 Jan 1, In : Food Chemistry. 141, 4, p. 3627-3635 9 p.

Research output: Contribution to journalArticle

piperine
fatty liver
High Fat Diet
high fat diet
Nutrition
2012
14 Citations (Scopus)

Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feeding

Cha, A., Choi, Y., Jin, Y., Sung, M. K., Koo, Y. C., Lee, K. W. & Park, T., 2012 Jan 3, In : Journal of Biomedicine and Biotechnology. 2012, 141395.

Research output: Contribution to journalArticle

Codonopsis
Methanol
Anti-Inflammatory Agents
Ethanol
Liver
45 Citations (Scopus)

Carvacrol prevents diet-induced obesity by modulating gene expressions involved in adipogenesis and inflammation in mice fed with high-fat diet

Cho, S., Choi, Y., Park, S. & Park, T., 2012 Feb 1, In : Journal of Nutritional Biochemistry. 23, 2, p. 192-201 10 p.

Research output: Contribution to journalArticle

Adipogenesis
High Fat Diet
Nutrition
Gene expression
Obesity
8 Citations (Scopus)

Cinchonine prevents high-fat-diet-induced obesity through downregulation of adipogenesis and adipose inflammation

Jung, S. A., Choi, M., Kim, S., Yu, R. & Park, T., 2012 Jun 20, In : PPAR Research. 541204.

Research output: Contribution to journalArticle

Adipogenesis
High Fat Diet
Down-Regulation
Obesity
Inflammation
21 Citations (Scopus)

Extract from Dioscorea batatas ameliorates insulin resistance in mice fed a high-fat diet

Kim, S., Jwa, H., Yanagawa, Y. & Park, T., 2012 Jun 1, In : Journal of medicinal food. 15, 6, p. 527-534 8 p.

Research output: Contribution to journalArticle

Dioscorea
High Fat Diet
Insulin Resistance
Facilitative Glucose Transport Proteins
Membrane Transport Proteins
39 Citations (Scopus)
Adipogenesis
Intra-Abdominal Fat
Thermogenesis
Nutrition
Obesity
59 Citations (Scopus)

Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice

Kim, S. J., Choi, Y., Choi, Y. H. & Park, T., 2012 Feb 1, In : Journal of Nutritional Biochemistry. 23, 2, p. 113-122 10 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Adipose Tissue
Obesity
Tissue
Nutrition