• 1633 Citations
  • 20 h-Index
1988 …2020

Research output per year

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Research Output

  • 1633 Citations
  • 20 h-Index
  • 49 Article
  • 2 Review article
  • 1 Book
  • 1 Chapter
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Article

A conserved arginine residue in the terminal protein domain of hepatitis B virus polymerase is critical for RNA pre-genome encapsidation

Shin, Y. C., Park, S. & Ryu, W. S., 2011 Aug 1, In : Journal of General Virology. 92, 8, p. 1809-1816 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Activated ras oncogene collaborates with HBx gene of hepatitis B virus to transform cells by suppressing HBx-mediated apoptosis

Kim, Y. C., Song, K. S., Yoon, G., Nam, M. J. & Ryu, W. S., 2001 Jan 4, In : Oncogene. 20, 1, p. 16-23 8 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

A novel cis-acting element facilitates minus-strand DNA synthesis during reverse transcription of the hepatitis B virus genome

Shin, M. K., Lee, J. & Ryu, W. S., 2004 Jun, In : Journal of Virology. 78, 12, p. 6252-6262 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A novel parvovirus isolated from Manchurian chipmunks

Yoo, B. C., Lee, D. H., Park, S. M., Park, J. W., Kim, C. Y., Lee, H. S., Seo, J. S., Park, K. J. & Ryu, W. S., 1999 Jan 20, In : Virology. 253, 2, p. 250-258 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Assembly of hepatitis delta virus particles

Ryu, W. S., Bayer, M. & Taylor, J., 1992, In : Journal of Virology. 66, 4, p. 2310-2315 6 p.

Research output: Contribution to journalArticle

Open Access
140 Citations (Scopus)

Association of hepatitis C virus particles with immunoglobulin: A mechanism for persistent infection

Choo, S. H., So, H. S., Cho, J. M. & Ryu, W. S., 1995 Jan 1, In : Journal of General Virology. 76, 9, p. 2337-2341 5 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
5 Citations (Scopus)

Circularization of an RNA template via long-range base pairing is critical for hepadnaviral reverse transcription

Shin, M. K., Kim, J. H., Ryu, D. K. & Ryu, W. S., 2008 Feb 20, In : Virology. 371, 2, p. 362-373 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

DDB1 stimulates viral transcription of hepatitis B virus via HBx-independent mechanisms

Kim, W., Lee, S., Son, Y., Ko, C. & Ryu, W. S., 2016 Jan 1, In : Journal of Virology. 90, 21, p. 9644-9653 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

DDX3 DEAD-box RNA helicase inhibits hepatitis B virus reverse transcription by incorporation into Nucleocapsids

Wang, H., Kim, S. & Ryu, W. S., 2009 Jun 1, In : Journal of Virology. 83, 11, p. 5815-5824 10 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

DDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional Level

Ko, C., Lee, S., Windisch, M. P. & Ryu, W. S., 2014 Jan 1, In : Journal of Virology. 88, 23, p. 13689-13698 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Development of a novel hepatitis B virus encapsidation detection assay by viral nucleocapsid-captured quantitative RT-PCR

Ryu, D. K., Ahn, Y., Ryu, W. S. & Windisch, M. P., 2015 Nov, In : BioTechniques. 59, 5, p. 287-293 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Development of transgenic chickens expressing enhanced green fluorescent protein

Kwon, M. S., Koo, B. C., Choi, B. R., Lee, H. T., Kim, Y. H., Ryu, W. S., Shim, H., Kim, J. H., Kim, N. H. & Kim, T., 2004 Jul 23, In : Biochemical and Biophysical Research Communications. 320, 2, p. 442-448 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Effect of a Novel Saponin Adjuvant Derived from Quillaja saponaria on the Immune Response to Recombinant Hepatitis B Surface Antigen

So, H. S., Yoon, H. S., Choi, D. Y., Kwon, Y. S., Sung, J. H., Lee, T. G., Park, E. S., Cho, H. S., Lee, B. M., Cho, J. M. & Ryu, W. S., 1997 Apr 30, In : Molecules and cells. 7, 2, p. 178-186 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Effect of S267F variant of NTCP on the patients with chronic hepatitis B

Lee, H. W., Park, H. J., Jin, B., Dezhbord, M., Kim, D. Y., Han, K. H., Ryu, W. S., Kim, S. & Ahn, S. H., 2017 Dec 1, In : Scientific reports. 7, 1, 17634.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Efficient long-term amplification of hepatitis B virus isolates after infection of slow proliferating HepG2-NTCP cells

König, A., Yang, J., Jo, E., Park, K. H. P., Kim, H., Than, T. T., Song, X., Qi, X., Dai, X., Park, S., Shum, D., Ryu, W. S., Kim, J. H., Yoon, S. K., Park, J. Y., Ahn, S. H., Han, K. H., Gerlich, W. H. & Windisch, M. P., 2019 Aug, In : Journal of Hepatology. 71, 2, p. 289-300 12 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Emergence of YMDD motif mutant of hepatitis B virus during short-term lamivudine therapy in South Korea

Paik, Y. H., Chung, H. Y., Ryu, W. S., Lee, K. S., Lee, J. S., Kim, J. H., Lee, C. K., Chon, C. Y., Moon, Y. M. & Han, K. H., 2001 Jul 25, In : Journal of Hepatology. 35, 1, p. 92-98 7 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Evidence that the 5'-end cap structure is essential for encapsidation of hepatitis B virus pregenomic RNA

Jeong, J. K., Yoon, G. S. & Ryu, W. S., 2000 Jun 22, In : Journal of Virology. 74, 12, p. 5502-5508 7 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Expression from herpesvirus promoters does not relieve the intron requirement for cytoplasmic accumulation of human β-globin mRNA

Yu, X. M., Gelembiuk, G. W., Wang, C. Y., Ryu, W. S. & Mertz, J. E., 1991 Dec 25, In : Nucleic acids research. 19, 25, p. 7231-7234 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Factors predictive of response to interferon-α therapy in hepatitis C virus type 1b infection

Yeh, B. I., Han, K. H., Lee, H. W., Sohn, J. H., Ryu, W. S., Yoon, D. J., Yoon, J., Kim, H. W., Kong, I. D., Chang, S. J. & Choi, J. W., 2002 Mar 19, In : Journal of Medical Virology. 66, 4, p. 481-487 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Four conserved cysteine residues of the hepatitis B virus polymerase are critical for RNA pregenome encapsidation

Kim, S., Lee, J. & Ryu, W. S., 2009 Aug 1, In : Journal of Virology. 83, 16, p. 8032-8040 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Genetic dissection of naturally occurring basal core promoter mutations of hepatitis B virus reveals a silent phenotype in the overlapping X gene

Hussain, Z., Jung, H. S., Ryu, D. K. & Ryu, W. S., 2009 Oct 5, In : Journal of General Virology. 90, 9, p. 2272-2281 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

HBx targeting to mitochondria and ROS generation are necessary but insufficient for HBV-induced cyclooxygenase-2 expression

Lim, W., Kwon, S. H., Cho, H., Kim, S., Lee, S., Ryu, W. S. & Cho, H., 2010 Apr 1, In : Journal of Molecular Medicine. 88, 4, p. 359-369 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels

Ko, C., Chakraborty, A., Chou, W. M., Hasreiter, J., Wettengel, J. M., Stadler, D., Bester, R., Asen, T., Zhang, K., Wisskirchen, K., McKeating, J. A., Ryu, W. S. & Protzer, U., 2018 Dec, In : Journal of Hepatology. 69, 6, p. 1231-1241 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: Implications for immune evasion

Wang, H. & Ryu, W. S., 2010 Jul, In : PLoS Pathogens. 6, 7, p. 1-11 11 p., e1000986.

Research output: Contribution to journalArticle

139 Citations (Scopus)

Hepatitis B virus polymerase suppresses translation of pregenomic RNA via a mechanism involving its interaction with 5′ stem-loop structure

Ryu, D. K., Kim, S. & Ryu, W. S., 2008 Mar 30, In : Virology. 373, 1, p. 112-123 12 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Hepatitis B virus X protein enhances Myc stability by inhibiting SCF Skp2 ubiquitin E3 ligase-mediated Myc ubiquitination and contributes to oncogenesis

Lee, S., Kim, W., Ko, C. & Ryu, W. S., 2016 Apr 7, In : Oncogene. 35, 14, p. 1857-1867 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Hepatitis B virus X protein is essential for the activation of Wnt/β-catenin signaling in hepatoma cells

Cha, M. Y., Kim, C. M., Park, Y. M. & Ryu, W. S., 2004 Jun 1, In : Hepatology. 39, 6, p. 1683-1693 11 p.

Research output: Contribution to journalArticle

177 Citations (Scopus)

Hepatitis delta virus mutant: Effect on RNA editing

Wu, T. T., Bichko, V. V., Ryu, W. S., Lemon, S. M. & Taylor, J. M., 1995 Nov, In : Journal of Virology. 69, 11, p. 7226-7231 6 p.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)

Hydrophobic residues of terminal protein domain of hepatitis B virus polymerase contribute to distinct steps in viral genome replication

Shin, Y. C., Ko, C. & Ryu, W. S., 2011 Dec 15, In : FEBS Letters. 585, 24, p. 3964-3968 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Identification and characterization of a novel hepatitis B virus pregenomic RNA encapsidation inhibitor

Jo, E., Ryu, D. K., König, A., Park, S., Cho, Y., Park, S. H., Kim, T. H., Yoon, S. K., Ryu, W. S., Cechetto, J. & Windisch, M. P., 2020 Mar, In : Antiviral Research. 175, 104709.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Incorporation of eukaryotic translation initiation factor eIF4E into viral nucleocapsids via interaction with hepatitis B virus polymerase

Kim, S., Wang, H. & Ryu, W. S., 2010 Jan 1, In : Journal of Virology. 84, 1, p. 52-58 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Inhibition of hepatitis B virus replication by ligand-mediated activation of RNase L

Park, I. H., Kwon, Y. C., Ryu, W. S. & Ahn, B. Y., 2014 Apr 1, In : Antiviral Research. 104, 1, p. 118-127 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Nucleotide sequence stability of the genome of hepatitis delta virus

Netter, H. J., Wu, T. T., Bockol, M., Cywinski, A., Ryu, W. S., Tennant, B. C. & Taylor, J. M., 1995 Mar, In : Journal of Virology. 69, 3, p. 1687-1692 6 p.

Research output: Contribution to journalArticle

Open Access
36 Citations (Scopus)

Polyadenylation is dispensable for encapsidation and reverse transcription of hepatitis B viral pregenomic RNA

Lee, H. J., Lee, J., Shin, M. K. & Ryu, W. S., 2008 Jun 30, In : Molecules and cells. 25, 4, p. 545-552 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Presentation of the hydrophilic domains of hepatitis C viral E2 envelope glycoprotein on hepatitis B surface antigen particles

Lee, I. H., Kim, C. H. & Ryu, W. S., 1996 Oct, In : Journal of Medical Virology. 50, 2, p. 145-151 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Proximity between the cap and 5′ ε stem-loop structure is critical for the suppression of pgRNA translation by the hepatitis B viral polymerase

Ryu, D. K., Ahn, B. Y. & Ryu, W. S., 2010 Oct 1, In : Virology. 406, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Residues Arg703, Asp777, and Arg781 of the rnase H domain of hepatitis B virus polymerase are critical for viral DNA synthesis

Ko, C., Shin, Y. C., Park, W. J., Kim, S., Kim, J. & Ryua, W. S., 2014 Jan, In : Journal of Virology. 88, 1, p. 154-163 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Ribonucleoprotein complexes of hepatitis delta virus

Ryu, W. S., Netter, H. J., Bayer, M. & Taylor, J., 1993, In : Journal of Virology. 67, 6, p. 3281-3287 7 p.

Research output: Contribution to journalArticle

Open Access
71 Citations (Scopus)
Open Access
75 Citations (Scopus)

Stimulation of hepatitis B virus genome replication by HBx is linked to both nuclear and cytoplasmic HBx expression

Cha, M. Y., Ryu, D. K., Jung, H. S., Chang, H. E. & Ryu, W. S., 2009 Jun 29, In : Journal of General Virology. 90, 4, p. 978-986 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

The FDA-approved drug irbesartan inhibits HBV-infection in HepG2 cells stably expressing sodium taurocholate co-transporting polypeptide

Ko, C., Park, W. J., Park, S., Kim, S., Windisch, M. P. & Ryu, W. S., 2015 Jan 1, In : Antiviral therapy. 20, 8, p. 835-842 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

The late spliced 19S and 16S RNAs of simian virus 40 can be synthesized from a common pool of transcripts

Good, P. J., Welch, R. C., Ryu, W. S. & Mertz, J. E., 1988, In : Journal of Virology. 62, 2, p. 563-571 9 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

The roles of the delta antigen in the structure and replication of hepatitis delta virus

Taylor, J., Chao, M., Hsieh, S. Y. & Wang-Shick, R., 1991, In : Journal of Hepatology. 13, SUPPL. 4, p. S119-S120

Research output: Contribution to journalArticle

8 Citations (Scopus)

Three novel cis-acting elements required for efficient plus-strand DNA synthesis of the hepatitis B virus genome

Lee, J., Shin, M. K., Lee, H. J., Yoon, G. & Ryu, W. S., 2004 Jul, In : Journal of Virology. 78, 14, p. 7455-7464 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Topical administration of the pan-Src kinase inhibitors, dasatinib and LCB 03-0110, prevents allergic contact dermatitis in mice

Jung, S. H., Sun, X., Ryu, W. S. & Yang, B. S., 2013 Jan 1, In : British Journal of Dermatology. 168, 1, p. 112-119 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Turnover of hepatitis B virus X protein is facilitated by Hdj1, a human Hsp40/DnaJ protein

Sohn, S. Y., Kim, J. H., Baek, K. W., Ryu, W. S. & Ahn, B. Y., 2006 Sep 1, In : Biochemical and Biophysical Research Communications. 347, 3, p. 764-768 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Versatile PCR-mediated insertion or deletion mutagenesis

Lee, J., Lee, H. J., Shin, M. K. & Ryu, W. S., 2004 Mar 1, In : BioTechniques. 36, 3, p. 398-400 3 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)