• 1370 Citations
  • 20 h-Index
20022020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Article

[18F]-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of β-amyloid fibrils

Lee, J. H., Byeon, S. R., Kim, Y. S., Lim, S. J., Oh, S. J., Moon, D. H., Yoo, K. H., Chung, B. Y. & Kim, D. J., 2008 Oct 15, In : Bioorganic and Medicinal Chemistry Letters. 18, 20, p. 5701-5704 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of β-amyloid aggregation

Lee, Y. S., Kim, H. Y., Youn, H. M., Seo, J. H., Kim, Y. & Shin, K. J., 2013 Nov 1, In : Bioorganic and Medicinal Chemistry Letters. 23, 21, p. 5882-5886 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model

Yang, S. H., Kim, J., Lee, M. J. & Kim, Y., 2015 Oct 27, In : Scientific reports. 5, 15703.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide

Kim, Y., Lillo, A., Moss, J. A. & Janda, K. D., 2005 Nov 1, In : Molecular Pharmaceutics. 2, 6, p. 528-535 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A

Ma, H., Zhou, B., Kim, Y. S. & Janda, K. D., 2006 Jun 15, In : Toxicon. 47, 8, p. 901-908 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide

Moss, J. A., Lillo, A., Kim, Y. S., Gao, C., Ditzel, H. & Janda, K. D., 2005 Jan 19, In : Journal of the American Chemical Society. 127, 2, p. 538-9 2 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice

Cho, S. M., Lee, S., Yang, S. H., Kim, H. Y., Lee, M. J., Kim, H. V., Kim, J., Baek, S., Yun, J., Kim, D., Kim, Y. K., Cho, Y., Woo, J., Kim, T. S. & Kim, Y. S., 2016 Feb 2, In : Scientific reports. 6, 20185.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A highly sensitive plasma-based amyloid-β detection system through medium-changing and noise cancellation system for early diagnosis of the Alzheimer's disease

Yoo, Y. K., Kim, J., Kim, G., Kim, Y. S., Kim, H. Y., Lee, S., Cho, W. W., Kim, S., Lee, S. M., Lee, B. C., Lee, J. H. & Hwang, K. S., 2017 Dec 1, In : Scientific reports. 7, 1, 8882.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model

Kim, H. V., Kim, H. Y., Ehrlich, H. Y., Choi, S. Y., Kim, D. J. & Kim, Y. S., 2013 Mar 1, In : Amyloid. 20, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Aminostyrylbenzofuran derivatives as potent inhibitors for Aβ fibril formation

Byun, J. H., Kim, H. Y., Kim, Y. S., Mook-Jung, I., Kim, D. J., Lee, W. K. & Yoo, K. H., 2008 Oct 15, In : Bioorganic and Medicinal Chemistry Letters. 18, 20, p. 5591-5593 3 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice

Lee, S. H., Kim, Y. S., Kim, H. Y., Kim, Y. H., Kim, M. S., Kong, J. Y., Lee, M. H., Kim, D. J. & Ahn, Y. G., 2014 Apr 23, In : PloS one. 9, 4, e95733.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a

Yang, Y., Kim, J., Kim, H. Y., Ryoo, N., Lee, S., Kim, Y. S., Rhim, H. & Shin, Y. K., 2015 Aug 25, In : Cell Reports. 12, 8, p. 1244-1251 8 p., 1940.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Anti-amyloidogenic approach to access amyloid-β(1-42) in Fmoc solid-phase synthesis

Lee, S. & Kim, Y. S., 2015 Aug 1, In : Bulletin of the Korean Chemical Society. 36, 8, p. 2147-2149 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice

Yang, S. H., Shin, J., Shin, N. N., Hwang, J-H., Hong, S-C., Park, K., Lee, J. W., Lee, S., Baek, S., Kim, K., Cho, I. & Kim, Y., 2019 Mar 12, In : Scientific reports. 9, 1, p. 4183

Research output: Contribution to journalArticle

2 Citations (Scopus)

Bimolecular fluorescence complementation; Lighting-up tau-tau interaction in living cells

Tak, H. J., Haque, M. M., Kim, M. J., Lee, J. H., Baik, J. H., Kim, Y. S., Kim, D. J., Grailhe, R. & Kim, Y. K., 2013 Dec 2, In : PloS one. 8, 12, e81682.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Biological tuning of synthetic tactics in solid-phase synthesis: application to A beta(1-42)

Kim, Y. S., Moss, J. A. & Janda, K. D., 2004 Oct 29, In : Journal of Organic Chemistry. 69, 22, p. 7776-8 3 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Bis-styrylnaphthalene and bis-styrylnaphthyridine derivatives with high binding affinity to β-amyloid fibrils

Lee, Y. R., Kim, Y. S. & Yoo, K. H., 2015 Jan 20, In : Bulletin of the Korean Chemical Society. 36, 1, p. 413-416 4 p.

Research output: Contribution to journalArticle

Cell surface GRP78 as a biomarker and target for suppressing glioma cells

Kang, B. R., Yang, S. H., Chung, B. R., Kim, W. & Kim, Y. S., 2016 Oct 7, In : Scientific reports. 6, 34922.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Comparative analyses of plasma amyloid-b levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system

Kim, Y. S., Yoo, Y. K., Kim, H. Y., Roh, J. H., Kim, J., Baek, S., Lee, J. C., Kim, H. J., Chae, M. S., Jeong, D., Park, D., Lee, S., Jang, H. C., Kim, K., Lee, J. H., Byun, B. H., Park, S. Y., Ha, J. H., Lee, K. C., Cho, W. W. & 4 others, Kim, J. S., Koh, J. Y., Lim, S. M. & Hwang, K. S., 2019 Jan 1, In : Science Advances. 5, 4, eaav1388.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system

Kim, Y., Yoo, Y. K., Kim, H. Y., Roh, J. H., Kim, J., Baek, S., Lee, J. C., Kim, H. J., Chae, M-S., Jeong, D., Park, D., Lee, S., Jang, H., Kim, K., Lee, J. H., Byun, B. H., Park, S. Y., Ha, J. H., Lee, K. C., Cho, W. W. & 4 others, Kim, J-S., Koh, J-Y., Lim, S. M. & Hwang, K. S., 2019 Apr 17, In : Science Advances. 5, 4, p. eaav1388

Research output: Contribution to journalArticle

Comparative resin kinetics using in situ fluorescence measurements

Walsh, D. P., Pang, C., Parikh, P. B., Kim, Y. S. & Chang, Y. T., 2002 May 1, In : Journal of Combinatorial Chemistry. 4, 3, p. 204-208 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model

Cho, S. M., Kim, H. V., Lee, S., Kim, H. Y., Kim, W., Kim, T. S., Kim, D. J. & Kim, Y. S., 2014 Oct 27, In : Scientific reports. 4, 6777.

Research output: Contribution to journalArticle

23 Citations (Scopus)

CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer's disease

Byun, J., Son, S. M., Cha, M. Y., Shong, M., Hwang, Y. J., Kim, Y., Ryu, H., Moon, M., Kim, K. S. & Mook-Jung, I., 2015 Jun 1, In : Cell Death and Differentiation. 22, 6, p. 959-973 15 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Destruction of ERP responses to deviance in an auditory oddball paradigm in amyloid infusion mice with memory deficits

Kim, B., Shin, J., Kim, Y. S. & Choi, J. H., 2020, In : PloS one. 15, 3

Research output: Contribution to journalArticle

Detection and quantification of plasma amyloid-β by selected reaction monitoring mass spectrometry

Kim, J. S., Ahn, H. S., Cho, S. M., Lee, J. E., Kim, Y. S. & Lee, C., 2014 Aug 20, In : Analytica Chimica Acta. 840, p. 1-9 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Dielectrophoresis-based filtration effect and detection of amyloid beta in plasma for Alzheimer's disease diagnosis

Kim, H. J., Park, D., Baek, S. Y., Yang, S. H., Kim, Y. S., Lim, S. M., Kim, J. & Hwang, K. S., 2019 Mar 1, In : Biosensors and Bioelectronics. 128, p. 166-175 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Dielectrophoresis-based filtration effect and detection of amyloid beta in plasma for Alzheimer's disease diagnosis

Kim, H. J., Park, D., Baek, S. Y., Yang, S. H., Kim, Y. S., Lim, S. M., Kim, J. & Hwang, K. S., 2019 Mar 1, In : Biosensors and Bioelectronics. 128, p. 166-175 10 p.

Research output: Contribution to journalArticle

Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis

Choi, J. W., Kim, H. Y., Jeon, M., Kim, D. J. & Kim, Y., 2012 Sep 1, In : Amyloid. 19, 3, p. 133-137 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Enhancing surface functionality of reduced graphene oxide biosensors by oxygen plasma treatment for Alzheimer's disease diagnosis

Chae, M. S., Kim, J., Jeong, D., Kim, Y. S., Roh, J. H., Lee, S. M., Heo, Y., Kang, J. Y., Lee, J. H., Yoon, D. S., Kim, T. G., Chang, S. T. & Hwang, K. S., 2017 Jun 15, In : Biosensors and Bioelectronics. 92, p. 610-617 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques

Kim, H. Y., Kim, H. V., Jo, S., Lee, C. J., Choi, S. Y., Kim, D. J. & Kim, Y., 2015 Dec 8, In : Nature communications. 6, 8997.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Fluorescence Chemicals to Detect Insoluble and Soluble Amyloid-β Aggregates

Lee, D., Kim, S. M., Kim, H. Y. & Kim, Y., 2019 Jun 19, In : ACS Chemical Neuroscience. 10, 6, p. 2647-2657 11 p.

Research output: Contribution to journalArticle

Fluorescent 1,4-Naphthoquinones to Visualize Diffuse and Dense-Core Amyloid Plaques in APP/PS1 Transgenic Mouse Brains

Neo Shin, N., Jeon, H., Jung, Y., Baek, S., Lee, S., Yoo, H. C., Bae, G. H., Park, K., Yang, S. H., Han, J. M., Kim, I. & Kim, Y., 2019 Jun 19, In : ACS Chemical Neuroscience. 10, 6, p. 3031-3044 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Fluorescent 1,4-Naphthoquinones To Visualize Diffuse and Dense-Core Amyloid Plaques in APP/PS1 Transgenic Mouse Brains

Neo Shin, N., Jeon, H., Jung, Y., Baek, S., Lee, S., Yoo, H. C., Bae, G. H., Park, K., Yang, S-H., Han, J. M., Kim, I. & Kim, Y., 2019 Apr 24, In : ACS Chemical Neuroscience.

Research output: Contribution to journalArticle

Four-week individual caging of male ICR mice alters body composition without change in body mass

Shin, J., Woo, J., Cho, Y., Choi, Y. H., Shin, N. N. & Kim, Y., 2018 Dec 1, In : Scientific reports. 8, 1, 1331.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Frontiers in Probing Alzheimer's Disease Biomarkers with Fluorescent Small Molecules

Jun, Y. W., Cho, S. W., Jung, J., Huh, Y., Kim, Y., Kim, D. & Ahn, K. H., 2019 Feb 27, In : ACS Central Science. 5, 2, p. 209-217 9 p.

Research output: Contribution to journalArticle

Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition

Yoon, B. E., Woo, J., Chun, Y. E., Chun, H., Jo, S., Bae, J. Y., An, H., Min, J. O., Oh, S. J., Han, K. S., Kim, H. Y., Kim, T., Kim, Y. S., Bae, Y. C. & Lee, C. J., 2014 Jan 1, In : Journal of Physiology. 592, 22, p. 4951-4968 18 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Identification of Plasma Membrane Glycoproteins Specific to Human Glioblastoma Multiforme Cells Using Lectin Arrays and LC-MS/MS

Park, Y. E., Yeom, J., Kim, Y. S., Lee, H. J., Han, K. C., Lee, S. T., Lee, C. & Lee, J. E., 2018 Jan 1, In : Proteomics. 18, 1

Research output: Contribution to journalArticle

Identification of Plasma Membrane Glycoproteins Specific to Human Glioblastoma Multiforme Cells Using Lectin Arrays and LC-MS/MS

Park, Y. E., Yeom, J., Kim, Y. S., Lee, H. J., Han, K. C., Lee, S. T., Lee, C. & Lee, J. E., 2018 Jan, In : Proteomics. 18, 1, 1700302.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Intracerebroventricular injection of amyloid-# peptides in normal mice to acutely induce alzheimer-like cognitive deficits

Kim, H. Y., Lee, D. K., Chung, B. R., Kim, H. V. & Kim, Y., 2016 Feb 24, In : Journal of Visualized Experiments. 2016, 109, e53308.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery

Liu, Y., Steiniger, S. C. J., Kim, Y. S., Kaufmann, G. F., Felding-Habermann, B. & Janda, K. D., 2007 May 1, In : Molecular Pharmaceutics. 4, 3, p. 435-447 13 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Multifunctionalized reduced graphene oxide biosensors for simultaneous monitoring of structural changes in amyloid-β 40

Jeong, D., Kim, J., Chae, M. S., Lee, W., Yang, S. H., Kim, Y., Kim, S. M., Lee, J. S., Lee, J. H., Choi, J., Yoon, D. S. & Hwang, K. S., 2018 Jun, In : Sensors (Switzerland). 18, 6, 1738.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Multifunctional Photonics Nanoparticles for Crossing the Blood–Brain Barrier and Effecting Optically Trackable Brain Theranostics

Singh, A., Kim, W., Kim, Y., Jeong, K., Kang, C. S., Kim, Y. S., Koh, J., Mahajan, S. D., Prasad, P. N. & Kim, S., 2016 Oct 18, In : Advanced Functional Materials. 26, 39, p. 7057-7066 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice

Yang, S. H., Lee, D. K., Shin, J., Lee, S., Baek, S., Kim, J., Jung, H., Hah, J. M. & Kim, Y. S., 2017 Jan 1, In : EMBO Molecular Medicine. 9, 1, p. 61-77 17 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Novel cyanine dyes with vinylsulfone group for labeling biomolecules

Park, J. W., Kim, Y., Lee, K. J. & Kim, D. J., 2012 Mar 21, In : Bioconjugate Chemistry. 23, 3, p. 350-362 13 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Peptide–nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?

Jeong, W. J., Bu, J., Kubiatowicz, L. J., Chen, S. S., Kim, Y. S. & Hong, S., 2018 Dec 1, In : Nano Convergence. 5, 1

Research output: Contribution to journalArticle

Preliminary PET Study of 18F-FC119S in Normal and Alzheimer's Disease Models

Oh, S. J., Kim, M. H., Han, S. J., Kang, K. J., Ko, I. O., Kim, Y., Park, J. A., Choi, J. Y., Lee, K. C., Chi, D. Y., Lee, Y. J. & Kim, K. M., 2017 Sep 5, In : Molecular Pharmaceutics. 14, 9, p. 3114-3120 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Preventive approach for overcoming dementia

Lee, H. Y., Kim, D. W., Lee, W., Kim, H. Y. & Kim, Y. S., 2019 Aug 1, In : Archives of pharmacal research. 42, 8, p. 647-657 11 p.

Research output: Contribution to journalArticle

Rapid and sustained cognitive recovery in APP/PS1 transgenic mice by co-administration of EPPS and donepezil

Kim, H. Y., Kim, H. V., Lee, D. K., Yang, S. H. & Kim, Y. S., 2016 Oct 31, In : Scientific reports. 6, 34165.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Reactive cyanine fluorescence dyes indicating ph perturbation of biomolecules

Park, J. W., Kim, D. J., Lee, K. J. & Kim, Y. S., 2013 Jan 20, In : Bulletin of the Korean Chemical Society. 34, 1, p. 287-290 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Real-time imaging of glioblastoma using bioluminescence in a U-87 MG xenograft model mouse

Kim, W., Kang, B. R., Kim, H. Y., Cho, S. M., Lee, Y. D., Kim, S., Kim, J. Y., Kim, D. J. & Kim, Y. S., 2015 Jan 1, In : Journal of the Korean Society for Applied Biological Chemistry. 58, 2, p. 243-248 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)