A malignant tumor consists of rapidly growing cancer cells, and requires a dedicated blood supply to provide oxygen and nutrients. Therefore, vascular endothelial growth factor (VEGF), a signal protein produced by cells stimulating angiogenesis, is considered as a key biomarker in clinical diagnosis of cancers , . There are already existing methods for the VEGF detection requiring advanced instruments and complex protocols . Recently, significant progress has been achieved in biosensors for the detection and quantification of VEGF using synthetic receptors . In particular, a capacitive biosensor detects the change of dielectric properties when the receptor binds to VEGF, and capacitance change can be used to quantify the reactions. However, the sensitivity of the capacitive biosensors still needs to be improved for use in cancer diagnosis.
|Title of host publication||2019 IEEE International Solid-State Circuits Conference, ISSCC 2019|
|Publisher||Institute of Electrical and Electronics Engineers Inc.|
|Number of pages||3|
|Publication status||Published - 2019 Mar 6|
|Event||2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 - San Francisco, United States|
Duration: 2019 Feb 17 → 2019 Feb 21
|Name||Digest of Technical Papers - IEEE International Solid-State Circuits Conference|
|Conference||2019 IEEE International Solid-State Circuits Conference, ISSCC 2019|
|Period||19/2/17 → 19/2/21|
Bibliographical noteFunding Information:
This work was supported by a Nano.Material Technology Development Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2014M3A7B4051594) and the IDEC, Korea.
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Electrical and Electronic Engineering