2019 update of the Korean clinical practice guidelines of stroke for endovascular recanalization therapy in patients with acute ischemic stroke

Sang Bae Ko, Hong Kyun Park, Byung Moon Kim, Ji Hoe Heo, Joung Ho Rha, Sun U. Kwon, Jong S. Kim, Byung Chul Lee, Sang Hyun Suh, Cheolkyu Jung, Hae Woong Jeong, Dong Hun Kang, Hee Joon Bae, Byung Woo Yoon, Keun Sik Hong

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Abstract

Endovascular recanalization therapy (ERT) has been a standard of care for patients with acute ischemic stroke due to large artery occlusion (LAO) within 6 hours after onset, since five landmark ERT trials conducted by 2015 demonstrated its clinical benefit. Recently, two randomized clinical trials demonstrated that ERT, even in the late time window of up to 16 hours or 24 hours after last known normal time, improved the outcome of patients who had a target mismatch, defined as either clinical-core mismatch or perfusion-core mismatch, which prompted the update of national guidelines in several countries. Accordingly, to provide evidence-based and up-to-date recommendations for ERT in patients with acute LAO in Korea, the Clinical Practice Guidelines Committee of the Korean Stroke Society decided to revise the previous Korean Clinical Practice Guidelines of Stroke for ERT. For this update, the members of the writing group were appointed by the Korean Stroke Society and the Korean Society of Interventional Neuroradiology. After thoroughly reviewing the updated evidence from two recent trials and relevant literature, the writing members revised recommendations, for which formal consensus was achieved by convening an expert panel composed of 45 experts from the participating academic societies. The current guidelines are intended to help healthcare providers, patients, and their caregivers make well-informed decisions and to improve the quality of care regarding ERT. The ultimate decision for ERT in a particular patient must be made in light of circumstances specific to that patient.

Original languageEnglish
Pages (from-to)231-240
Number of pages10
JournalJournal of Stroke
Volume21
Issue number2
DOIs
Publication statusPublished - 2019 May

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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    Ko, S. B., Park, H. K., Kim, B. M., Heo, J. H., Rha, J. H., Kwon, S. U., Kim, J. S., Lee, B. C., Suh, S. H., Jung, C., Jeong, H. W., Kang, D. H., Bae, H. J., Yoon, B. W., & Hong, K. S. (2019). 2019 update of the Korean clinical practice guidelines of stroke for endovascular recanalization therapy in patients with acute ischemic stroke. Journal of Stroke, 21(2), 231-240. https://doi.org/10.5853/jos.2019.00024