3D structure of individual nanocrystals in solution by electron microscopy

Jungwon Park, Hans Elmlund, Peter Ercius, Jong Min Yuk, David T. Limmer, Qian Chen, Kwanpyo Kim, Sang Hoon Han, David A. Weitz, A. Zettl, A. Paul Alivisatos

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

Knowledge about the synthesis, growth mechanisms, and physical properties of colloidal nanoparticles has been limited by technical impediments. We introduce a method for determining three-dimensional (3D) structures of individual nanoparticles in solution. We combine a graphene liquid cell, high-resolution transmission electron microscopy, a direct electron detector, and an algorithm for single-particle 3D reconstruction originally developed for analysis of biological molecules. This method yielded two 3D structures of individual platinum nanocrystals at near-atomic resolution. Because our method derives the 3D structure from images of individual nanoparticles rotating freely in solution, it enables the analysis of heterogeneous populations of potentially unordered nanoparticles that are synthesized in solution, thereby providing a means to understand the structure and stability of defects at the nanoscale.

Original languageEnglish
Pages (from-to)290-295
Number of pages6
JournalScience
Volume349
Issue number6245
DOIs
Publication statusPublished - 2015 Jul 17

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Nanocrystals
Electron microscopy
Nanoparticles
Graphite
High resolution transmission electron microscopy
Platinum
Physical properties
Detectors
Defects
Molecules
Electrons
Liquids

All Science Journal Classification (ASJC) codes

  • General

Cite this

Park, J., Elmlund, H., Ercius, P., Yuk, J. M., Limmer, D. T., Chen, Q., ... Alivisatos, A. P. (2015). 3D structure of individual nanocrystals in solution by electron microscopy. Science, 349(6245), 290-295. https://doi.org/10.1126/science.aab1343
Park, Jungwon ; Elmlund, Hans ; Ercius, Peter ; Yuk, Jong Min ; Limmer, David T. ; Chen, Qian ; Kim, Kwanpyo ; Han, Sang Hoon ; Weitz, David A. ; Zettl, A. ; Alivisatos, A. Paul. / 3D structure of individual nanocrystals in solution by electron microscopy. In: Science. 2015 ; Vol. 349, No. 6245. pp. 290-295.
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Park, J, Elmlund, H, Ercius, P, Yuk, JM, Limmer, DT, Chen, Q, Kim, K, Han, SH, Weitz, DA, Zettl, A & Alivisatos, AP 2015, '3D structure of individual nanocrystals in solution by electron microscopy', Science, vol. 349, no. 6245, pp. 290-295. https://doi.org/10.1126/science.aab1343

3D structure of individual nanocrystals in solution by electron microscopy. / Park, Jungwon; Elmlund, Hans; Ercius, Peter; Yuk, Jong Min; Limmer, David T.; Chen, Qian; Kim, Kwanpyo; Han, Sang Hoon; Weitz, David A.; Zettl, A.; Alivisatos, A. Paul.

In: Science, Vol. 349, No. 6245, 17.07.2015, p. 290-295.

Research output: Contribution to journalArticle

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AU - Elmlund, Hans

AU - Ercius, Peter

AU - Yuk, Jong Min

AU - Limmer, David T.

AU - Chen, Qian

AU - Kim, Kwanpyo

AU - Han, Sang Hoon

AU - Weitz, David A.

AU - Zettl, A.

AU - Alivisatos, A. Paul

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Park J, Elmlund H, Ercius P, Yuk JM, Limmer DT, Chen Q et al. 3D structure of individual nanocrystals in solution by electron microscopy. Science. 2015 Jul 17;349(6245):290-295. https://doi.org/10.1126/science.aab1343