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2019
8 Citations (Scopus)

A multicenter phase II study of AMG 337 in patients with MET-amplified gastric/gastroesophageal junction/esophageal adenocarcinoma and other MET-amplified solid tumors

Van Cutsem, E., Karaszewska, B., Kang, Y. K., Chung, H. C., Shankaran, V., Siena, S., Go, N. F., Yang, H., Schupp, M. & Cunningham, D., 2019 Apr 15, In : Clinical Cancer Research. 25, 8, p. 2414-2423 10 p.

Research output: Contribution to journalArticle

Esophagogastric Junction
Stomach
Adenocarcinoma
Neoplasms
Disease-Free Survival
2 Citations (Scopus)

A phase II, randomised study of mFOLFOX6 with or without the Akt inhibitor ipatasertib in patients with locally advanced or metastatic gastric or gastroesophageal junction cancer

Bang, Y. J., Kang, Y. K., Ng, M., Chung, H., Wainberg, Z. A., Gendreau, S., Chan, W. Y., Xu, N., Maslyar, D., Meng, R., Chau, I. & Ajani, J. A., 2019 Feb 1, In : European Journal of Cancer. 108, p. 17-24 8 p.

Research output: Contribution to journalArticle

Esophagogastric Junction
Stomach
Disease-Free Survival
Placebos
Neoplasms
7 Citations (Scopus)

Avelumab (anti-PD-L1) as first-line switch-maintenance or second-line therapy in patients with advanced gastric or gastroesophageal junction cancer: Phase 1b results from the JAVELIN Solid Tumor trial

Chung, H. C., Arkenau, H. T., Lee, J., Rha, S. Y., Oh, D. Y., Wyrwicz, L., Kang, Y. K., Lee, K. W., Infante, J. R., Lee, S. S., Kemeny, M., Keilholz, U., Melichar, B., Mita, A., Plummer, R., Smith, D., Gelb, A. B., Xiong, H., Hong, J., Chand, V. & 1 others, Safran, H., 2019 Feb 4, In : Journal for ImmunoTherapy of Cancer. 7, 1, 30.

Research output: Contribution to journalArticle

Esophagogastric Junction
Stomach
Maintenance
Disease-Free Survival
Neoplasms
1 Citation (Scopus)

Behaviors and attitudes toward the use of complementary and alternative medicine among Korean cancer patients

Kwon, J. H., Lee, S. C., Lee, M. A., Kim, Y. J., Kang, J. H., Kim, J. Y., Lee, H. J., Bae, W. K., Kim, M. J., Chie, E. K., Kim, J., Kim, Y. H., Chung, H. C. & Rha, S. Y., 2019 Jul 1, In : Cancer Research and Treatment. 51, 3, p. 851-860 10 p.

Research output: Contribution to journalArticle

Open Access
Complementary Therapies
Neoplasms
Republic of Korea
Odds Ratio
Confidence Intervals

Changes in taste and food preferences in breast cancer patients receiving chemotherapy: a pilot study

Kim, Y. H., Kim, G. M., Son, S., Song, M., Park, S., Chung, H. C. & Lee, S. M., 2019 Jan 1, In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

Food Preferences
Breast Neoplasms
Drug Therapy
Taste Threshold
Malnutrition

Comprehensive immune profiling and immune-monitoring using body fluid of patients with metastatic gastric cancer

Park, H. S., Kwon, W. S., Park, S., Jo, E., Lim, S. J., Lee, C. K., Lee, J. B., Jung, M., Kim, H. S., Beom, S. H., Park, J. Y., Kim, T. S., Chung, H. C. & Rha, S. Y., 2019 Oct 21, In : Journal for ImmunoTherapy of Cancer. 7, 1, 268.

Research output: Contribution to journalArticle

Open Access
Immunologic Monitoring
Body Fluids
Stomach Neoplasms
T-Lymphocytes
Vascular Endothelial Growth Factor A
3 Citations (Scopus)

Differences in the efficacies of pazopanib and gemcitabine/docetaxel as second-line treatments for metastatic soft tissue sarcoma

Kim, J. H., Park, H. S., Heo, S. J., Kim, S. K., Han, J. W., Shin, K. H., Kim, S. H., Hur, H., Kim, K. S., Choi, Y. D., Kim, S., Lee, Y. H., Suh, J. S., Ahn, J. B., Chung, H. C., Noh, S. H., Rha, S. Y. & Kim, H. S., 2019 Feb 1, In : Oncology (Switzerland). 96, 2, p. 59-69 11 p.

Research output: Contribution to journalArticle

docetaxel
gemcitabine
Sarcoma
Therapeutics
Synovial Sarcoma
1 Citation (Scopus)

Effect of First-line S-1 Plus Oxaliplatin With or Without Ramucirumab Followed by Paclitaxel Plus Ramucirumab on Advanced Gastric Cancer in East Asia: The Phase 2 RAINSTORM Randomized Clinical Trial

Yoshikawa, T., Muro, K., Shitara, K., Oh, D. Y., Kang, Y. K., Chung, H. C., Kudo, T., Chin, K., Kadowaki, S., Hamamoto, Y., Hironaka, S., Yoshida, K., Yen, C. J., Omuro, Y., Bai, L. Y., Maeda, K., Ozeki, A., Yoshikawa, R. & Kitagawa, Y., 2019 Aug 2, In : JAMA network open. 2, 8, p. e198243

Research output: Contribution to journalArticle

Open Access
oxaliplatin
Far East
Paclitaxel
Stomach Neoplasms
Randomized Controlled Trials
31 Citations (Scopus)

Efficacy and safety of pembrolizumab in previously treated advanced cervical cancer: Results from the phase II KEYNOTE-158 study

Chung, H. C., Ros, W., Delord, J. P., Perets, R., Italiano, A., Shapira-Frommer, R., Manzuk, L., Piha-Paul, S. A., Xu, L., Zeigenfuss, S., Pruitt, S. K. & Leary, A., 2019 Jan 1, In : Journal of Clinical Oncology. 37, 17, p. 1470-1478 9 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Safety
Drug Therapy
Neoplasms
pembrolizumab

Immunohistochemistry biomarkers predict survival in stage II/III gastric cancer patients: From a prospective clinical trial

Kim, M. H., Zhang, X., Jung, M., Jung, I., Park, H. S., Beom, S. H., Kim, H. S., Rha, S. Y., Kim, H., Choi, Y. Y., Son, T., Kim, H. I., Cheong, J. H., Hyung, W. J., Noh, S. H. & Chung, H. C., 2019 Jan 1, In : Cancer Research and Treatment. 51, 2, p. 819-831 13 p.

Research output: Contribution to journalArticle

Open Access
Thymidylate Synthase
Stomach Neoplasms
oxaliplatin
Biomarkers
Immunohistochemistry
1 Citation (Scopus)

Inhibiting casein kinase 2 overcomes paclitaxel resistance in gastric cancer

Jung, M., Park, K. H., Kim, H. M., Kim, T. S., Zhang, X., Park, S. M., Beom, S. H., Kim, H. S., Cheong, J. H., Chung, H. C., Soong, J., Lin, S. C. & Rha, S. Y., 2019 Nov 1, In : Gastric Cancer. 22, 6, p. 1153-1163 11 p.

Research output: Contribution to journalArticle

Casein Kinase II
Paclitaxel
Stomach Neoplasms
Heterografts
Phosphatidylinositol 3-Kinase
1 Citation (Scopus)

Landscape of actionable genetic alterations profiled from 1,071 tumor samples in Korean cancer patients

Lee, S. H., Lee, B., Shim, J. H., Lee, K. W., Yun, J. W., Kim, S. Y., Kim, T. Y., Kim, Y. H., Ko, Y. H., Chung, H. C., Yu, C. S., Lee, J., Rha, S. Y., Kim, T. W., Jung, K. H., Im, S. A., Moon, H. G., Cho, S., Kang, J. H., Kim, J. & 10 others, Kim, S. K., Ryu, H. S., Ha, S. Y., Kim, J. I., Chung, Y. J., Kim, C., Kim, H. L., Park, W. Y., Noh, D. Y. & Park, K., 2019 Jan 1, In : Cancer Research and Treatment. 51, 1, p. 211-222 12 p.

Research output: Contribution to journalArticle

Open Access
Neoplasms
Paraffin
Formaldehyde
Precision Medicine
Workflow
3 Citations (Scopus)

Maintenance avelumab versus continuation of first-line chemotherapy in gastric cancer: JAVELIN Gastric 100 study design

Moehler, M., Ryu, M. H., Dvorkin, M., Lee, K. W., Coşkun, H., Wong, R., Chung, H. C., Poltoratsky, A., Tsuji, A., Yen, C. J., Muntean, A. S., Le Sourd, S., Vaccaro, G. M., Overton, L., Boku, N., Wainberg, Z. A., Patel, M., Sharma, M., Xiong, H., Conti, I. & 2 others, Taieb, J. & Bang, Y. J., 2019 Feb, In : Future Oncology. 15, 6, p. 567-577 11 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Esophagogastric Junction
Stomach
oxaliplatin
Maintenance
1 Citation (Scopus)

Mesothelin Expression Is a Predictive Factor for Peritoneal Recurrence in Curatively Resected Stage III Gastric Cancer

Shin, S. J., Park, S., Kim, M. H., Nam, C. M., Kim, H., Choi, Y. Y., Jung, M. K., Choi, H. J., Rha, S. Y. & Chung, H. C., 2019 Nov 1, In : Oncologist. 24, 11, p. e1108-e1114

Research output: Contribution to journalArticle

Stomach Neoplasms
Recurrence
Survival
Neoplasms
mesothelin
9 Citations (Scopus)

Pembrolizumab alone or in combination with chemotherapy as first-line therapy for patients with advanced gastric or gastroesophageal junction adenocarcinoma: results from the phase II nonrandomized KEYNOTE-059 study

Bang, Y. J., Kang, Y. K., Catenacci, D. V., Muro, K., Fuchs, C. S., Geva, R., Hara, H., Golan, T., Garrido, M., Jalal, S. I., Borg, C., Doi, T., Yoon, H. H., Savage, M. J., Wang, J., Dalal, R. P., Shah, S., Wainberg, Z. A. & Chung, H. C., 2019 Jan 1, In : Gastric Cancer.

Research output: Contribution to journalArticle

Open Access
Esophagogastric Junction
Combination Drug Therapy
Stomach
Adenocarcinoma
Therapeutics

Phase II trial of preoperative sequential chemotherapy followed by chemoradiotherapy for high-risk gastric cancer

Kim, H. S., Koom, W. S., Baek, S. E., Kim, H. I., Jung, M., Beom, S. H., Kang, B., Kim, H., Chang, J. S., Choi, Y. Y., Son, T., Cheong, J. H., Noh, S. H., Kim, E. H., Park, J. C., Shin, S. K., Lee, S. K., Lee, Y. C., Shin, S. J., Chung, H. & 5 others, Jung, I., Chung, H. C., Lim, J. S., Hyung, W. J. & Rha, S. Y., 2019 Nov, In : Radiotherapy and Oncology. 140, p. 143-149 7 p.

Research output: Contribution to journalArticle

Chemoradiotherapy
Stomach Neoplasms
Drug Therapy
docetaxel
Cisplatin
1 Citation (Scopus)

Prognostic role of body composition parameters in gastric/gastroesophageal junction cancer patients from the EXPAND trial

Hacker, U. T., Hasenclever, D., Linder, N., Stocker, G., Chung, H. C., Kang, Y. K., Moehler, M., Busse, H. & Lordick, F., 2019 Jan 1, (Accepted/In press) In : Journal of Cachexia, Sarcopenia and Muscle.

Research output: Contribution to journalArticle

Open Access
Esophagogastric Junction
Body Composition
Stomach
Muscles
Survival

Randomised phase II trial comparing four front-line doublets in Asian patients with metastatic gastric cancer

Kim, C., Chon, H. J., Kim, J. H., Jung, M., Nam, C. M., Kim, H. S., Kang, B., Chung, H. C. & Rha, S. Y., 2019 May, In : European Journal of Cancer. 112, p. 20-28 9 p.

Research output: Contribution to journalArticle

docetaxel
Fluorouracil
Stomach Neoplasms
Paclitaxel
Disease-Free Survival
4 Citations (Scopus)

Role of probe-based confocal laser endomicroscopy-targeted biopsy in the molecular and histopathological study of gastric cancer

Park, C. H., Kim, H., Jo, J. H., Hahn, K. Y., Yoon, J. H., Kim, S. Y., Lee, Y. C., Noh, S. H., Chung, H. C. & Lee, S. K., 2019 Jan, In : Journal of Gastroenterology and Hepatology (Australia). 34, 1, p. 84-91 8 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Lasers
Endoscopy
Biopsy
Light
4 Citations (Scopus)

S-1 based doublet as an adjuvant chemotherapy for curatively resected stage III gastric cancer: Results from the randomized phase III POST trial

Lee, C. K., Jung, M., Kim, H. S., Jung, I., Shin, D. B., Kang, S. Y., Zang, D. Y., Kim, K. H., Lee, M. H., Kim, B. S., Lee, K. H., Cheong, J. H., Hyung, W. J., Noh, S. H., Chung, H. C. & Rha, S. Y., 2019 Jan 1, In : Cancer Research and Treatment. 51, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Cisplatin
Stomach Neoplasms
docetaxel
oxaliplatin
11 Citations (Scopus)

Safety and efficacy of nivolumab in combination with s-1/capecitabine plus oxaliplatin in patients with previously untreated, unresectable, advanced, or recurrent gastric/gastroesophageal junction cancer: Interim results of a randomized, phase II trial (attraction-4)

Boku, N., Ryu, M. H., Kato, K., Chung, H. C., Minashi, K., Lee, K. W., Cho, H., Kang, W. K., Komatsu, Y., Tsuda, M., Yamaguchi, K., Hara, H., Fumita, S., Azuma, M., Chen, L. T. & Kang, Y. K., 2019 Feb 1, In : Annals of Oncology. 30, 2, p. 250-258 9 p.

Research output: Contribution to journalArticle

Open Access
oxaliplatin
Esophagogastric Junction
Stomach
Safety
Neoplasms

Temsirolimus in Asian Metastatic/Recurrent Non-clear Cell Renal Carcinoma

Lee, J. B., Park, H. S., Park, S., Lee, H. J., Kwon, K. A., Choi, Y. J., Kim, Y. J., Nam, C. M., Cho, N. H., Kang, B., Chung, H. C. & Rha, S. Y., 2019 Oct 1, In : Cancer research and treatment : official journal of Korean Cancer Association. 51, 4, p. 1578-1588 11 p.

Research output: Contribution to journalArticle

Open Access
Renal Cell Carcinoma
Disease-Free Survival
Confidence Intervals
Survival
Nephrectomy
2018
6 Citations (Scopus)

Alpha-fetoprotein kinetics in patients with hepatocellular carcinoma receiving ramucirumab or placebo: An analysis of the phase 3 REACH study

Chau, I., Park, J. O., Ryoo, B. Y., Yen, C. J., Poon, R., Pastorelli, D., Blanc, J. F., Kudo, M., Pfiffer, T., Hatano, E., Chung, H. C., Kopeckova, K., Phelip, J. M., Brandi, G., Ohkawa, S., Li, C. P., Okusaka, T., Hsu, Y., Abada, P. B. & Zhu, A. X., 2018 Jul 3, In : British journal of cancer. 119, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

alpha-Fetoproteins
Hepatocellular Carcinoma
Placebos
Survival
Therapeutics

A Prediction Model of Tumor Progression and Survival in HER2-Positive Metastatic Gastric Cancer Patients Treated with Trastuzumab and Chemotherapy

Chae, D., Nam, C. M., Kim, J. H., Lee, C. K., Kim, S. S., Kim, H. S., Jung, M., Cheong, J. H., Chung, H. C., Rha, S. Y. & Park, K., 2018 Jul 1, In : AAPS Journal. 20, 4, 72.

Research output: Contribution to journalArticle

Stomach Neoplasms
Drug Therapy
Survival
Neoplasms
Fluorouracil
1 Citation (Scopus)

Casein kinase 2 inhibitor, CX-4945, as a potential targeted anticancer agent in gastric cancer

Kim, H. M., Jeong, I., Kim, H. J., Kang, S. K., Kwon, W. S., Kim, T. S., Park, K. H., Jung, M., Soong, J., Lin, S. C., Chung, H. C. & Rha, S. Y., 2018 Nov, In : Anticancer research. 38, 11, p. 6171-6180 10 p.

Research output: Contribution to journalArticle

Casein Kinase II
Antineoplastic Agents
Stomach Neoplasms
Cell Line
Exome
3 Citations (Scopus)

Corrigendum to ‘Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib: Patient-focused outcome results from the randomised phase III REACH study’ [Eur J Canc 81 (2017) 17–25] (S0959804917309334) (10.1016/j.ejca.2017.05.001))

Chau, I., Peck-Radosavljevic, M., Borg, C., Malfertheiner, P., Seitz, J. F., Park, J. O., Ryoo, B. Y., Yen, C. J., Kudo, M., Poon, R., Pastorelli, D., Blanc, J. F., Chung, H. C., Baron, A. D., Okusaka, T., Bowman, L., Cui, Z. L., Girvan, A. C., Abada, P. B., Yang, L. & 1 others, Zhu, A. X., 2018 Sep, In : European Journal of Cancer. 100, p. 135-136 2 p.

Research output: Contribution to journalComment/debate

Hepatocellular Carcinoma
Stomach
Emotions
Pain
Therapeutics

Efficacy and Safety of Ixabepilone and Capecitabine in Patients With Advanced Triple-negative Breast Cancer: a Pooled Analysis From Two Large Phase III, Randomized Clinical Trials

Rugo, H. S., Roche, H., Thomas, E., Chung, H. C., Lerzo, G. L., Vasyutin, I., Patel, A. & Vahdat, L., 2018 Dec, In : Clinical Breast Cancer. 18, 6, p. 489-497 9 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Phase III Clinical Trials
Randomized Controlled Trials
Safety
Confidence Intervals
47 Citations (Scopus)

Efficacy and safety of pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma: Pooled analyses after long-term follow-up in KEYNOTE-012

Mehra, R., Seiwert, T. Y., Gupta, S., Weiss, J., Gluck, I., Eder, J. P., Burtness, B., Tahara, M., Keam, B., Kang, H., Muro, K., Geva, R., Chung, H. C., Lin, C. C., Aurora-Garg, D., Ray, A., Pathiraja, K., Cheng, J., Chow, L. Q. M. & Haddad, R., 2018 Jul 17, In : British journal of cancer. 119, 2, p. 153-159 7 p.

Research output: Contribution to journalArticle

Safety
Therapeutics
Carcinoma, squamous cell of head and neck
pembrolizumab
Survival
5 Citations (Scopus)

Forty-nine gastric cancer cell lines with integrative genomic profiling for development of c-MET inhibitor

Kim, H. J., Kang, S. K., Kwon, W. S., Kim, T. S., Jeong, I., Jeung, H. C., Kragh, M., Horak, I. D., Chung, H. C. & Rha, S. Y., 2018 Jul 1, In : International Journal of Cancer. 143, 1, p. 151-159 9 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Cell Line
Hepatocyte Growth Factor
Proto-Oncogene Proteins c-met
Pharmaceutical Preparations

Identification of natural products as novel PI3Kβ inhibitors through pharmacophore-based virtual screening

Jin, X., Kwon, W., Kim, T. S., Heo, J. N., Chung, H., Choi, J. & No, K. T., 2018 Mar 1, In : Bulletin of the Korean Chemical Society. 39, 3, p. 294-299 6 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Biological Products
Screening
Phosphoric Monoester Hydrolases
Molecular dynamics
9 Citations (Scopus)

Marked Loss of Muscle, Visceral Fat, or Subcutaneous Fat After Gastrectomy Predicts Poor Survival in Advanced Gastric Cancer: Single-Center Study from the CLASSIC Trial

Park, H. S., Kim, H. S., Beom, S. H., Rha, S. Y., Chung, H. C., Kim, J. H., Chun, Y. J., Lee, S. W., Choe, E. A., Heo, S. J., Noh, S. H., Hyung, W. J., Cheong, J. H., Kim, H. I., Son, T., Lim, J. S., Baek, S. E. & Jung, M., 2018 Oct 1, In : Annals of surgical oncology. 25, 11, p. 3222-3230 9 p.

Research output: Contribution to journalArticle

Intra-Abdominal Fat
Subcutaneous Fat
Gastrectomy
Stomach Neoplasms
Body Composition
4 Citations (Scopus)

MET in gastric cancer with liver metastasis: The relationship between MET amplification and Met overexpression in primary stomach tumors and liver metastasis

Kim, H. S., Chon, H. J., Kim, H., Shin, S. J., Wacheck, V., Gruver, A. M., Kim, J. S., Rha, S. Y. & Chung, H. C., 2018 Jun 15, In : Journal of surgical oncology. 117, 8, p. 1679-1686 8 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Stomach Neoplasms
Stomach
Neoplasm Metastasis
Liver
8 Citations (Scopus)

Multidisciplinary treatment for patients with stage IV gastric cancer: The role of conversion surgery following chemotherapy 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

Beom, S. H., Choi, Y. Y., Baek, S. E., Li, S. X., Lim, J. S., Son, T., Kim, H. I., Cheong, J. H., Hyung, W., Choi, S. H., Jung, M., Kim, H. S., Jeung, H. C., Chung, H., Rha, S. & Noh, S. H., 2018 Nov 15, In : BMC cancer. 18, 1, 1116.

Research output: Contribution to journalArticle

Stomach Neoplasms
Carcinogenesis
Drug Therapy
Health
Gastrectomy
11 Citations (Scopus)

Pembrolizumab in Asia-Pacific patients with advanced head and neck squamous cell carcinoma: Analyses from KEYNOTE-012

Tahara, M., Muro, K., Hasegawa, Y., Chung, H. C., Lin, C. C., Keam, B., Takahashi, K., Cheng, J. D. & Bang, Y. J., 2018 Mar, In : Cancer Science. 109, 3, p. 771-776 6 p.

Research output: Contribution to journalArticle

Confidence Intervals
Safety
Carcinoma, squamous cell of head and neck
pembrolizumab
Survival
152 Citations (Scopus)

Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial

KEYNOTE-061 investigators, 2018 Jul 14, In : The Lancet. 392, 10142, p. 123-133 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Paclitaxel
Stomach
Cell Death
Survival
68 Citations (Scopus)

Phase III, randomised trial of avelumab versus physician's choice of chemotherapy as third-line treatment of patients with advanced gastric or gastro-oesophageal junction cancer: Primary analysis of JAVELIN Gastric 300

Bang, Y. J., Yañez Ruiz, E., Van Cutsem, E., Lee, K. W., Wyrwicz, L., Schenker, M., Alsina, M., Ryu, M. H., Chung, H. C., Evesque, L., Al-Batran, S. E., Park, S. H., Lichinitser, M., Boku, N., Moehler, M. H., Hong, J., Xiong, H., Hallwachs, R., Conti, I. & Taieb, J., 2018 Jan 1, In : Annals of Oncology. 29, 10, p. 2052-2060 9 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Stomach
Physicians
Drug Therapy
Stomach Neoplasms
6 Citations (Scopus)

Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcoma

Cho, Y. J., Kim, S. H., Kim, E. K., Han, J. W., Shin, K. H., Hu, H., Kim, K. S., Choi, Y. D., Kim, S., Lee, Y. H., Suh, J. S., Ahn, J. B., Chung, H. C., Noh, S. H., Rha, S. Y., Jung, S. T. & Kim, H. S., 2018 Feb 7, In : BMC cancer. 18, 1, 158.

Research output: Contribution to journalArticle

Histone Code
Sarcoma
Survival
Polycomb Repressive Complex 2
Proteins
2 Citations (Scopus)

Ramucirumab safety in East Asian patients: A meta-analysis of six global, randomized, double-blind, placebo-controlled, phase III clinical trials

Yen, C. J., Muro, K., Kim, T. W., Kudo, M., Shih, J. Y., Lee, K. W., Chao, Y., Kim, S. W., Yamazaki, K., Sohn, J. H., Cheng, R., Zhang, Y., Binder, P., Mi, G., Orlando, M. & Chung, H. C., 2018 Mar 1, In : Journal of Global Oncology. 2018, 4

Research output: Contribution to journalArticle

Phase III Clinical Trials
Meta-Analysis
Placebos
Safety
ramucirumab
3 Citations (Scopus)

Real-time tumor gene expression profiling to direct gastric cancer chemotherapy: Proof-of-concept "3G" trial

Yong, W. P., Rha, S. Y., Tan, I. B. H., Choo, S. P., Syn, N. L., Koh, V., Tan, S. H., Asuncion, B. R., Sundar, R., So, J. B. Y., Shabbir, A., Tan, C. S., Kim, H. S., Jung, M., Chung, H. C., Ng, M. C. H., Tai, D. W. M., Lee, M. H., Wu, J., Yeoh, K. G. & 1 others, Tan, P., 2018 Nov 1, In : Clinical Cancer Research. 24, 21, p. 5272-5281 10 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
oxaliplatin
Stomach Neoplasms
Drug Therapy
Neoplasms

Regulation of proliferation and invasion by the IGF signalling pathway in Epstein-Barr virus-positive gastric cancer

Jeong, I., Kang, S. K., Kwon, W. S., Kim, H. J., Kim, K. H., Kim, H. M., Lee, A., Lee, S. K., Bogenrieder, T., Chung, H. C. & Rha, S. Y., 2018 Dec, In : Journal of Cellular and Molecular Medicine. 22, 12, p. 5899-5908 10 p.

Research output: Contribution to journalArticle

Somatomedins
Human Herpesvirus 4
Stomach Neoplasms
Cell Cycle
Sincalide
1 Citation (Scopus)

Subgroup analysis of East Asian patients in REGARD: A phase III trial of ramucirumab and best supportive care for advanced gastric cancer

Chung, H. C., Kok, V. C., Cheng, R., Hsu, Y., Orlando, M., Fuchs, C. & Cho, J. Y., 2018 Jun, In : Asia-Pacific Journal of Clinical Oncology. 14, 3, p. 204-209 6 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Placebos
ramucirumab
Confidence Intervals
Safety
3 Citations (Scopus)

The prognostic value of volume-based parameters using 18F-FDG PET/CT in gastric cancer according to HER2 status

Park, J. S., Lee, N., Beom, S. H., Kim, H. S., Lee, C. K., Rha, S. Y., Chung, H. C., Yun, M., Cho, A. & Jung, M., 2018 Mar 1, In : Gastric Cancer. 21, 2, p. 213-224 12 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Stomach Neoplasms
Tumor Burden
Disease-Free Survival
Survival
2017
1 Citation (Scopus)

ABCB1 2677G>T/A variant enhances chemosensitivity to anti-cancer agents acting on microtubule dynamics through LAMP1 inhibition

Kwon, W. S., Rha, S., Jeung, H. C., Ahn, J. B., Jung, J. J., Ki, D. H., Kim, T. S. & Chung, H., 2017 Jan 1, In : Biochemical Pharmacology. 123, p. 73-84 12 p.

Research output: Contribution to journalArticle

Microtubules
Genes
Neoplasms
Cells
Microarray Analysis
30 Citations (Scopus)

A first-time-in-human study of GSK2636771, a phosphoinositide 3 kinase beta-selective inhibitor, in patients with advanced solid tumors

Mateo, J., Ganji, G., Lemech, C., Burris, H. A., Han, S. W., Swales, K., Decordova, S., DeYoung, M. P., Smith, D. A., Kalyana-Sundaram, S., Wu, J., Motwani, M., Kumar, R., Tolson, J. M., Rha, S. Y., Chung, H. C., Eder, J. P., Sharma, S., Bang, Y. J., Infante, J. R. & 3 others, Yan, L., De Bono, J. S. & Arkenau, H. T., 2017 Oct 1, In : Clinical Cancer Research. 23, 19, p. 5981-5992 12 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Neoplasms
Phosphatidylinositol 3-Kinases
Prostatic Neoplasms
Hypophosphatemia
3 Citations (Scopus)

A non-randomized, open-label, single-arm, Phase 2 study of emibetuzumab in Asian patients with MET diagnostic positive, advanced gastric cancer

Sakai, D., Chung, H. C., Oh, D. Y., Park, S. H., Kadowaki, S., Kim, Y. H., Tsuji, A., Komatsu, Y., Kang, Y. K., Uenaka, K., Wijayawardana, S. R., Wacheck, V., Wang, X., Yamamura, A. & Doi, T., 2017 Dec 1, In : Cancer Chemotherapy and Pharmacology. 80, 6, p. 1197-1207 11 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Stomach Neoplasms
Labels
Tumors
Safety
1 Citation (Scopus)

A phase 1, open label, dose escalation study to investigate the safety, tolerability, and pharmacokinetics of MG1102 (apolipoprotein(a) Kringle V) in patients with solid tumors

Kim, G. M., Reid, T., Shin, S. J., Rha, S. Y., Ahn, J. B., Lee, S. S. & Chung, H. C., 2017 Dec 1, In : Investigational New Drugs. 35, 6, p. 773-781 9 p.

Research output: Contribution to journalArticle

Kringles
Apoprotein(a)
Pharmacokinetics
Safety
Neoplasms
7 Citations (Scopus)

Cardiotoxicity of trastuzumab in patients with HER2-positive gastric cancer

Park, J. S., Youn, J. C., Shim, C. Y., Hong, G. R., Lee, C. K., Kim, J. H., Park, H. S., Heo, S. J., Beom, S. H., Kim, H. S., Rha, S. Y., Chung, H. C., Kang, S. M. & Jung, M., 2017 Sep 1, In : Oncotarget. 8, 37, p. 61837-61845 9 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Stroke Volume
Drug Therapy
Cardiotoxicity
Trastuzumab
1 Citation (Scopus)

Changes in telomerase activity due to alternative splicing of human telomerase reverse transcriptase in colorectal cancer

Jeung, H. C., Rha, S. Y., Shin, S. J., Ahn, J. B., Park, K. H., Kim, T. S., Kim, J. J., Roh, J. K. & Chung, H. C., 2017 Jan 1, In : Oncology Letters. 14, 2, p. 2385-2392 8 p.

Research output: Contribution to journalArticle

Telomerase
Alternative Splicing
Colorectal Neoplasms
human TERT protein
Reverse Transcription
5 Citations (Scopus)

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer

Kim, H. S., Lee, H., Shin, S. J., Beom, S. H., Jung, M., Bae, S., Lee, E. Y., Park, K. H., Choi, Y. Y., Son, T., Kim, H. I., Cheong, J. H., Hyung, W. J., Park, J. C., Shin, S. K., Lee, S. K., Lee, Y. C., Koom, W. S., Lim, J. S., Chung, H. C. & 4 others, Noh, S. H., Rha, S. Y., Kim, H. & Paik, S., 2017 Jan 1, In : Oncotarget. 8, 24, p. 38389-38398 10 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Immunohistochemistry
Therapeutics
Receptor, Fibroblast Growth Factor, Type 2
PTEN Phosphohydrolase
7 Citations (Scopus)

Depth of response is a significant predictor for long-term outcome in advanced gastric cancer patients treated with trastuzumab

Lee, C. K., Kim, S. S., Park, S., Kim, C., Heo, S. J., Lim, J. S., Kim, H., Kim, H. S., Rha, S. Y., Chung, H. C., Park, S. & Jung, M., 2017 Jan 1, In : Oncotarget. 8, 19, p. 31169-31179 11 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Disease-Free Survival
Neoplasms
Survival
Confidence Intervals