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  • KwangHyub Han
2018

Combination of transient elastography and an enhanced liver fibrosis test to assess the degree of liver fibrosis in patients with chronic hepatitis B

Heo, J. Y., Kim, B. K., Park, J. Y., Kim, D. Y., Ahn, S. H., Kim, H. S., Park, Y. N., Han, K. H., Song, K. & Kim, S. U., 2018 Mar, In : Gut and liver. 12, 2, p. 190-200 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Daclatasvir plus asunaprevir for the treatment of patients with hepatitis C virus genotype 1b infection: Real-world efficacy, changes in liver stiffness and fibrosis markers, and safety

Lee, H. W., Oh, S. R., Kim, D. Y., Jeong, Y., Kim, S., Kim, B. K., Kim, S. U., Kim, D. Y., Ahn, S. H., Han, K. H. & Park, J. Y., 2018 May, In : Gut and liver. 12, 3, p. 324-330 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Downstaging with Localized Concurrent Chemoradiotherapy Can Identify Optimal Surgical Candidates in Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Chong, J. U., Choi, G. H., Han, D. H., Kim, K. S., Seong, J., Han, K. & Choi, J. S., 2018 Oct 1, In : Annals of Surgical Oncology. 25, 11, p. 3308-3315 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Effects of Virologic Response to Treatment on Short- and Long-term Outcomes of Patients With Chronic Hepatitis B Virus Infection and Decompensated Cirrhosis

Jang, J. W., Choi, J. Y., Kim, Y. S., Yoo, J. J., Woo, H. Y., Choi, S. K., Jun, C. H., Lee, C. H., Sohn, J. H., Tak, W. Y., Lee, Y. R. & Han, K. H., 2018 Dec, In : Clinical Gastroenterology and Hepatology. 16, 12, p. 1954-1963.e3

Research output: Contribution to journalArticle

9 Citations (Scopus)

Evolution and persistence of resistance-associated substitutions of hepatitis C virus after direct-acting antiviral treatment failures

Jeong, Y., Jin, B., Lee, H. W., Park, H. J., Park, J. Y., Kim, D. Y., Han, K. H., Ahn, S. H. & Kim, S., 2018 Nov, In : Journal of Viral Hepatitis. 25, 11, p. 1251-1259 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Feasibility of dynamic risk prediction for hepatocellular carcinoma development in patients with chronic hepatitis B

Jeon, M. Y., Lee, H. W., Kim, S. U., Kim, B. K., Park, J. Y., Kim, D. Y., Han, K. H. & Ahn, S. H., 2018 Apr, In : Liver International. 38, 4, p. 676-686 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
3 Citations (Scopus)

HCV phylogenetic signature and prevalence of pretreatment NS5A and NS5B NI-Resistance associated substitutions in HCV-Infected patients in Mainland China

Wei, L., Omata, M., Lim, Y. S., Xie, Q., Hou, J. L., Jia, J., Hedskog, C., Martin, R., Doehle, B., Yang, J., De-Oertel, S., Massetto, B., Kersey, K., Brainard, D. M., Svarovskaia, E., Mo, H., Han, K. H., Mizokami, M. & Duan, Z., 2018 Oct, In : Antiviral Research. 158, p. 178-184 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Impact of controlled attenuation parameter on detecting fibrosis using liver stiffness measurement

Karlas, T., Petroff, D., Sasso, M., Fan, J. G., Mi, Y. Q., de Lédinghen, V., Kumar, M., Lupsor-Platon, M., Han, K. H., Cardoso, A. C., Ferraioli, G., Chan, W. K., Wong, V. W. S., Myers, R. P., Chayama, K., Friedrich-Rust, M., Beaugrand, M., Shen, F., Hiriart, J. B., Sarin, S. K. & 12 others, Badea, R., Lee, H. W., Marcellin, P., Filice, C., Mahadeva, S., Wong, G. L. H., Crotty, P., Masaki, K., Bojunga, J., Bedossa, P., Keim, V. & Wiegand, J., 2018 Apr, In : Alimentary Pharmacology and Therapeutics. 47, 7, p. 989-1000 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial

Kudo, M., Finn, R. S., Qin, S., Han, K. H., Ikeda, K., Piscaglia, F., Baron, A., Park, J. W., Han, G., Jassem, J., Blanc, J. F., Vogel, A., Komov, D., Evans, T. R. J., Lopez, C., Dutcus, C., Guo, M., Saito, K., Kraljevic, S., Tamai, T. & 2 others, Ren, M. & Cheng, A. L., 2018 Mar 24, In : The Lancet. 391, 10126, p. 1163-1173 11 p.

Research output: Contribution to journalArticle

507 Citations (Scopus)
7 Citations (Scopus)

Predictors of failure to detect early hepatocellular carcinoma in patients with chronic hepatitis B who received regular surveillance

Chon, Y. E., Jung, K. S., Kim, M. J., Choi, J. Y., An, C., Park, J. Y., Ahn, S. H., Kim, B. K., Kim, S. U., Park, H., Hwang, S. K., Rim, K. S., Han, K. H. & Kim, D. Y., 2018 Apr, In : Alimentary Pharmacology and Therapeutics. 47, 8, p. 1201-1212 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
6 Citations (Scopus)

Reproducibility of European Association for the Study of the Liver criteria and modified Response Evaluation Criteria in Solid Tumors in patients treated with sorafenib

Jeon, M. Y., Lee, H. W., Kim, B. K., Park, J. Y., Kim, D. Y., Ahn, S. H., Han, K. H., Baek, S. E., Kim, H. S., Kim, S. U. & Park, M. S., 2018 Sep, In : Liver International. 38, 9, p. 1655-1663 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Responses are durable for up to 5 years after completion of peginterferon alfa-2a treatment in hepatitis B e antigen-positive patients

Chuang, W. L., Jia, J., Chan, H. L. Y., Han, K. H., Tanwandee, T., Tan, D., Chen, X., Gane, E., Piratvisuth, T., Chen, L., Xie, Q., Sung, J. J. Y., Messinger, D., Wat, C., Bakalos, G. & Liaw, Y. F., 2018 May, In : Alimentary Pharmacology and Therapeutics. 47, 9, p. 1306-1316 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Safety and Efficacy of Transarterial Radioembolization Combined with Chemoembolization for Bilobar Hepatocellular Carcinoma: A Single-Center Retrospective Study

Kwon, J. H., Kim, G. M., Han, K., Won, J. Y., Kim, M. D., Lee, D. Y., Lee, J., Choi, W., Kim, Y. S., Kim, D. Y. & Han, K. H., 2018 Mar 1, In : Cardiovascular and interventional radiology. 41, 3, p. 459-465 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Sarcopenia is associated with the risk of significant liver fibrosis in metabolically unhealthy subjects with chronic hepatitis B

Han, E., Lee, Y. H., Kim, B. K., Park, J. Y., Kim, D. Y., Ahn, S. H., Lee, B. W., Kang, E. S., Cha, B. S., Han, K. H. & Kim, S. U., 2018 Aug, In : Alimentary Pharmacology and Therapeutics. 48, 3, p. 300-312 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Serotonin signals through a gut-liver axis to regulate hepatic steatosis

Choi, W., Namkung, J., Hwang, I., Kim, H., Lim, A., Park, H. J., Lee, H. W., Han, K. H., Park, S., Jeong, J. S., Bang, G., Kim, Y. H., Yadav, V. K., Karsenty, G., Ju, Y. S., Choi, C., Suh, J. M., Park, J. Y., Park, S. & Kim, H., 2018 Dec 1, In : Nature communications. 9, 1, 4824.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Sofosbuvir and ledipasvir are associated with high sustained virologic response and improvement of health-related quality of life in East Asian patients with hepatitis C virus infection

Younossi, Z. M., Stepanova, M., Henry, L., Han, K. H., Ahn, S. H., Lim, Y. S., Chuang, W. L., Kao, J. H., Nguyen, K. V., Lai, C. L., Chan, H. L. Y. & Wei, L., 2018 Dec, In : Journal of Viral Hepatitis. 25, 12, p. 1429-1437 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Staging for hepatocellular carcinoma in light of tumor heterogeneity: Time to change or update?

Kim, D. Y. & Han, K. H., 2018 Jun, In : Hepatology. 67, 6, p. 2076-2078 3 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)
6 Citations (Scopus)

The effect of interferon-free regimens on health-related quality of life in East Asian patients with chronic hepatitis C

Younossi, Z. M., Stepanova, M., Henry, L., Han, K. H., Ahn, S. H., Lim, Y. S., Chuang, W. L., Kao, J. H., Kinh, N., Lai, C. L., Yuen, M. F., Chan, H. L. Y. & Lai, W., 2018 Jul, In : Liver International. 38, 7, p. 1179-1187 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Treatment of hepatocellular carcinoma with Lenvatinib

Han, K., 2018 Nov 1, In : Gastroenterology and Hepatology. 14, 11, p. 662-664 3 p.

Research output: Contribution to journalComment/debate

2017

Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis

Baatarkhuu, O., Lee, H. W., George, J., Munkh-Orshikh, D., Enkhtuvshin, B., Ariunaa, S., Eslam, M., Ahn, S. H., Han, K. H. & Kim, D. Y., 2017 Jun 1, In : Clinical and Molecular Hepatology. 23, 2, p. 147-153 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update

Omata, M., Cheng, A. L., Kokudo, N., Kudo, M., Lee, J. M., Jia, J., Tateishi, R., Han, K. H., Chawla, Y. K., Shiina, S., Jafri, W., Payawal, D. A., Ohki, T., Ogasawara, S., Chen, P. J., Lesmana, C. R. A., Lesmana, L. A., Gani, R. A., Obi, S., Dokmeci, A. K. & 1 others, Sarin, S. K., 2017 Jul 1, In : Hepatology International. 11, 4, p. 317-370 54 p.

Research output: Contribution to journalEditorial

308 Citations (Scopus)

Cell culture-adaptive mutations of NS5A affect replication of hepatitis C virus differentially depending on the viral genotypes

Chung, A., Jin, B., Han, K., Ahn, S. & Kim, S., 2017 Jan 1, In : Journal of Medical Virology. 89, 1, p. 146-152 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1 Citation (Scopus)

Conventional versus drug-eluting beads chemoembolization for hepatocellular carcinoma: Emphasis on the impact of tumor size

Lee, Y. K., Jung, K. S., kim, D., Choi, J. Y., Kim, B. K., Kim, S., Park, J., Ahn, S., Han, K., Kim, G. M., Kim, M., Park, S. I., Won, J. Y. & Lee, D. Y., 2017 Feb 1, In : Journal of Gastroenterology and Hepatology (Australia). 32, 2, p. 487-496 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

Kahan, B. C., Koulenti, D., Arvaniti, K., Beavis, V., Campbell, D., Chan, M., Moreno, R., Pearse, R. M., Pearse, R. M., Beattie, S., Clavien, P-A., Demartines, N., Fleisher, L. A., Grocott, M., Haddow, J., Hoeft, A., Holt, P., Moreno, R., Pritchard, N., Rhodes, A. & 30 others, Wijeysundera, D., Wilson, M., Ahmed, T., Everingham, K., Hewson, R., Januszewska, M., Pearse, R. M., Phull, M-K., Lee, E., Choi, S., Chen, C., Han, Y., Yang, S., Han, K., Chen, C., Chu, S., Chung, C. K. E., Lee, C., Lee, Y. C., Lee, H. S., Lee, J. M., Choi, H-MD., Kim, C. J., Kim, S., Park, K., Chang, Y. H., Chang, J., Lee, C., Lee, G. & Kim, T., 2017, In : Intensive Care Medicine. 43, 7

Research output: Contribution to journalArticle

58 Citations (Scopus)

Diagnosis of Hepatocellular Carcinoma with Non-Invasive Imaging: A Plea for Worldwide Adoption of Standard and Precise Terminology for Describing Enhancement Criteria

Piscaglia, F., Kudo, M., Han, K. H. & Sirlin, C., 2017 Feb 1, In : Ultraschall in der Medizin. 38, 1, p. 9-11 3 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Dickkopf-1 induces angiogenesis via VEGF receptor 2 regulation independent of the Wnt signaling pathway

Choi, S. H., Kim, H., Lee, H. G., Kim, B. K., Park, J. Y., Kim, D. Y., Ahn, S. H., Han, K. H. & Kim, S. U., 2017 Jan 1, In : Oncotarget. 8, 35, p. 58974-58984 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
5 Citations (Scopus)

Effect of S267F variant of NTCP on the patients with chronic hepatitis B

Lee, H. W., Park, H. J., Jin, B., Dezhbord, M., Kim, D. Y., Han, K. H., Ryu, W. S., Kim, S. & Ahn, S. H., 2017 Dec 1, In : Scientific reports. 7, 1, 17634.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Effect of yttrium-90 radioembolization on outcomes in Asian patients with early to advanced stage hepatocellular carcinoma

Woo, H. Y., Kim, D. Y., Heo, J., Kim, C. W., Kim, S., Yoon, K. T., Lim, W., Hong, Y. M., Won, J. Y., Lee, S., Han, K. H. & Cho, M., 2017 Apr, In : Hepatology Research. 47, 5, p. 387-397 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effects of entecavir and tenofovir on renal function in patients with hepatitis B virus-related compensated and decompensated cirrhosis

Park, J., Jung, K. S., Lee, H. W., Kim, B. K., Kim, S. U., Kim, D. Y., Ahn, S. H., Han, K. H. & Park, J. Y., 2017 Nov, In : Gut and liver. 11, 6, p. 828-834 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Estimating the cost-effectiveness of one-time screening and treatment for hepatitis C in Korea

Kim, D. Y., Han, K. H., Jun, B., Kim, T. H., Park, S., Ward, T., Webster, S. & McEwan, P., 2017 Jan, In : PloS one. 12, 1, 0167770.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Gamma-glutamyl transpeptidase-to-platelet ratio is an independent predictor of hepatitis B virus-related liver cancer

Park, Y. E., Kim, B. K., Park, J. Y., Kim, D. Y., Ahn, S. H., Han, K. H., Han, S., Jeon, M. Y., Heo, J. Y., Song, K. & Kim, S. U., 2017 Jun, In : Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1221-1229 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Improvement of Liver Fibrosis after Long-Term Antiviral Therapy Assessed by Fibroscan in Chronic Hepatitis B Patients with Advanced Fibrosis

Chon, Y. E., Park, J. Y., Myoung, S. M., Jung, K. S., Kim, B. K., Kim, S. U., Kim, D. Y., Ahn, S. H. & Han, K. H., 2017 Jun 1, In : American Journal of Gastroenterology. 112, 6, p. 882-891 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis

Karlas, T., Petroff, D., Sasso, M., Fan, J. G., Mi, Y. Q., de Lédinghen, V., Kumar, M., Lupsor-Platon, M., Han, K., Cardoso, A. C., Ferraioli, G., Chan, W. K., Wong, V. W. S., Myers, R. P., Chayama, K., Friedrich-Rust, M., Beaugrand, M., Shen, F., Hiriart, J. B., Sarin, S. K. & 12 others, Badea, R., Jung, K. S., Marcellin, P., Filice, C., Mahadeva, S., Wong, G. L. H., Crotty, P., Masaki, K., Bojunga, J., Bedossa, P., Keim, V. & Wiegand, J., 2017 May 1, In : Journal of Hepatology. 66, 5, p. 1022-1030 9 p.

Research output: Contribution to journalArticle

155 Citations (Scopus)

Less fibrotic burden differently affects the long-term outcomes of hepatocellular carcinoma after curative resection

Lee, H. W., Choi, G. H., Kim, D. Y., Park, Y. N., Kim, K. S., Choi, J. S., Ahn, S. H. & Han, K. H., 2017 Sep 1, In : Oncology (Switzerland). 93, 4, p. 224-232 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Liver fibrosis assessed with transient elastography is an independent risk factor for ischemic stroke

Kim, S. U., Song, D., Heo, J. H., Yoo, J., Kim, B. K., Park, J. Y., Kim, D. Y., Ahn, S. H., Kim, K. J., Han, K. H. & Kim, Y. D., 2017 May 1, In : Atherosclerosis. 260, p. 156-162 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Long-term follow-up of patients after autologous bone marrow cell infusion for decompensated liver cirrhosis

Kim, J. K., Kim, S. J., Kim, Y., Chung, Y. E., Park, Y. N., Kim, H. O., Kim, J. S., Park, M. S., Sakaida, I., Kim, D. Y., Lee, J. I., Ahn, S. H., Lee, K. S. & Han, K. H., 2017 Jan 1, In : Cell transplantation. 26, 6, p. 1059-1066 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

NS5A resistance-associated substitutions in patients with genotype 1 hepatitis C virus: Prevalence and effect on treatment outcome

Zeuzem, S., Mizokami, M., Pianko, S., Mangia, A., Han, K. H., Martin, R., Svarovskaia, E., Dvory-Sobol, H., Doehle, B., Hedskog, C., Yun, C., Brainard, D. M., Knox, S., McHutchison, J. G., Miller, M. D., Mo, H., Chuang, W. L., Jacobson, I., Dore, G. J. & Sulkowski, M., 2017 May, In : Journal of Hepatology. 66, 5, p. 910-918 9 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Obesity is more closely related with hepatic steatosis and fibrosis measured by transient elastography than metabolic health status

Huh, J. H., Kim, K. J., Kim, S., Han, S. H., Han, K., Cha, B. S., Chung, C. H. & lee, B., 2017 Jan 1, In : Metabolism: Clinical and Experimental. 66, p. 23-31 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
5 Citations (Scopus)

Prognostic clinical factors associated with remission and relapse in bullous pemphigoid

Lee, J. H., Kim, T. H., Park, S. H., Han, K. & Kim, S. C., 2017 Jan 1, In : Journal of the European Academy of Dermatology and Venereology. 31, 1, p. 81-84 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Prognostic factors of sorafenib therapy in hepatocellular carcinoma patients with failure of transarterial chemoembolization

Lee, S., Kang, J. H., Kim, D. Y., Ahn, S. H., Park, J. Y., Kim, B. K., Kim, S. U. & Han, K. H., 2017 May 1, In : Hepatology International. 11, 3, p. 292-299 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Prognostic Value of FDG Uptake of Portal Vein Tumor Thrombosis in Patients with Locally Advanced Hepatocellular Carcinoma

Lee, J. W., Hwang, S. H., Kim, D. Y., Han, K. H. & Yun, M., 2017 Jan 1, In : Clinical nuclear medicine. 42, 1, p. e35-e40

Research output: Contribution to journalArticle

7 Citations (Scopus)

Pro-tumorigenic roles of TGF-β signaling during the early stages of liver tumorigenesis through upregulation of Snail

Moon, H., Han, K. H. & Ro, S. W., 2017 Dec 1, In : BMB reports. 50, 12, p. 599-600 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Risk stratification for locally advanced hepatocellular carcinoma using pretreatment alpha-foetoprotein and 18F-fluoro-2-deoxyglucose positron emission tomography

Rhee, W. J., Hwang, S. H., Byun, H. K., Yun, M., Han, K. & Seong, J., 2017 Apr 1, In : Liver International. 37, 4, p. 592-599 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)