A Battery-Powered Opto-Electrophysiology Neural Interface with Artifact-Preventing Optical Pulse Shaping

Adam E. Mendrela, Sung Yun Park, Mihály Vöröslakos, Michael P. Flynn, Euisik Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

We present a neural interface IC for high-precision optical stimulation and electrical recording from implanted optoelectrodes with the highest system integration to date. The system combines 12 high-resolution constant-current LED driver channels, 32 recording channels, and an efficient PMU for operation from a low voltage Li battery on a wireless platform. A novel LED driver architecture features a high-efficiency wide-current-range fully-integrated voltage regulator and a high-resolution pulse shaper to minimize recording artifacts from sharp current pulse edges. A prototype, fabricated in 0.18μm CMOS, occupies 7.35mm2. The LED driver has a peak efficiency of 50% and consumes 31μW quiescent power. We demonstrate in-vivo that the pulse-shaping scheme prevents stimulation artifacts. Key Words: neural interface, LED driver, optogenetics.

Original languageEnglish
Title of host publication2018 IEEE Symposium on VLSI Circuits, VLSI Circuits 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages125-126
Number of pages2
ISBN (Electronic)9781538667002
DOIs
Publication statusPublished - 2018 Oct 22
Event32nd IEEE Symposium on VLSI Circuits, VLSI Circuits 2018 - Honolulu, United States
Duration: 2018 Jun 182018 Jun 22

Publication series

NameIEEE Symposium on VLSI Circuits, Digest of Technical Papers
Volume2018-June

Other

Other32nd IEEE Symposium on VLSI Circuits, VLSI Circuits 2018
CountryUnited States
CityHonolulu
Period18/6/1818/6/22

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

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  • Cite this

    Mendrela, A. E., Park, S. Y., Vöröslakos, M., Flynn, M. P., & Yoon, E. (2018). A Battery-Powered Opto-Electrophysiology Neural Interface with Artifact-Preventing Optical Pulse Shaping. In 2018 IEEE Symposium on VLSI Circuits, VLSI Circuits 2018 (pp. 125-126). [8502353] (IEEE Symposium on VLSI Circuits, Digest of Technical Papers; Vol. 2018-June). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/VLSIC.2018.8502353