We synthesized a benzthiazole-based chemosensor with mixed S,N donor sites. The binding units are incorporated in a highly flexible tripodal framework which facilitates the complexation of the binding of larger-sized metals. The chemosensor resulted in the sensitive and selective recognition of Ba 2+ through the enhancement of the fluorescence intensity when studied in a THF/H2O (8:2, v/v) solvent mixture. The sensor offers an interesting opportunity to monitor Ba2+ in biological samples including the cytoplasm of microbes such as Saccharomyces cerevisiae.
Bibliographical noteFunding Information:
This work was supported by an India–Korea Joint Program of Cooperation in Science &Technology, an ISIRD grant from IIT Ropar, and the CBMH. PS is thankful to the UGC India for a research fellowship. We thank Mr. S. Soni of CSIO Chandigarh for fluorescence microscopy assistance.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry