A benzthiazole-based tripodal chemosensor for Ba2+ recognition under biological conditions

Preeti Saluja, Navneet Kaur, Narinder Singh, Doo Ok Jang

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13 Citations (Scopus)

Abstract

We synthesized a benzthiazole-based chemosensor with mixed S,N donor sites. The binding units are incorporated in a highly flexible tripodal framework which facilitates the complexation of the binding of larger-sized metals. The chemosensor resulted in the sensitive and selective recognition of Ba 2+ through the enhancement of the fluorescence intensity when studied in a THF/H2O (8:2, v/v) solvent mixture. The sensor offers an interesting opportunity to monitor Ba2+ in biological samples including the cytoplasm of microbes such as Saccharomyces cerevisiae.

Original languageEnglish
Pages (from-to)6705-6708
Number of pages4
JournalTetrahedron Letters
Volume52
Issue number50
DOIs
Publication statusPublished - 2011 Dec 14

Bibliographical note

Funding Information:
This work was supported by an India–Korea Joint Program of Cooperation in Science &Technology, an ISIRD grant from IIT Ropar, and the CBMH. PS is thankful to the UGC India for a research fellowship. We thank Mr. S. Soni of CSIO Chandigarh for fluorescence microscopy assistance.

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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