A case of autoimmune hypoglycemia complicated with diabetic ketoacidosis

Myoung Sook Shim, Moonyoung Kim, Mi Jin Kim, Yeon Lee, Byung Jun Lee, Choon Hee Chung, Young Goo Shin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Autoimmune hypoglycemia is characterized by hyperinsulinemia, fasting hypoglycemia, and the presence of insulin auto-antibodies without previous exposure to exogenous insulin. We experienced a case of autoimmune hypoglycemia without diabetes mellitus or any evidence of insulinoma. The insulin auto-antibody and insulin receptor auto-antibody were present. We diagnosed the patient as having autoimmune hypoglycemia and treated with glucocorticoid. After treatment, the hypoglycemic symptoms were resolved. However, four months later, the patient was readmitted with transient diabetic ketoacidosis. After recovery, he showed no signs of diabetes mellitus. We believe that insulin auto-antibodies may play a role in autoimmune hypoglycemia and diabetic ketoacidosis, but its role and mechanism are not precisely known. Further studies are needed to define the action mechanisms and the functions of insulin auto-antibodies: here we present case with a relevant literature.

Original languageEnglish
Pages (from-to)140-144
Number of pages5
JournalYonsei medical journal
Volume45
Issue number1
DOIs
Publication statusPublished - 2004 Feb 29

Fingerprint

Diabetic Ketoacidosis
Insulin Antibodies
Hypoglycemia
Diabetes Mellitus
Insulinoma
Insulin Receptor
Hyperinsulinism
Hypoglycemic Agents
Glucocorticoids
Insulin
Antibodies

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Shim, Myoung Sook ; Kim, Moonyoung ; Kim, Mi Jin ; Lee, Yeon ; Lee, Byung Jun ; Chung, Choon Hee ; Shin, Young Goo. / A case of autoimmune hypoglycemia complicated with diabetic ketoacidosis. In: Yonsei medical journal. 2004 ; Vol. 45, No. 1. pp. 140-144.
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A case of autoimmune hypoglycemia complicated with diabetic ketoacidosis. / Shim, Myoung Sook; Kim, Moonyoung; Kim, Mi Jin; Lee, Yeon; Lee, Byung Jun; Chung, Choon Hee; Shin, Young Goo.

In: Yonsei medical journal, Vol. 45, No. 1, 29.02.2004, p. 140-144.

Research output: Contribution to journalArticle

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