A case of disseminated cutaneous nocardiosis due to Nocardia brasiliensis diagnosed by fine needle aspiration biopsy and 16s ribosomal RNA sequencing

Jung U. Shin, Yeon Sook Kwon, Hee Jung Kim, Yongjung Park, Kyungwon Lee, Kwang Hoon Lee

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Nocardiosis is a rare, life-threatening infection in the immunocompromised host. The causative bacteria are members of the genus Nocardia and are filamentous gram-positive bacilli that usually infect the lung, skin, and central nervous systems. Cutaneous nocardiosis presents as a disseminated infection or as a primary infection resulting from inoculation. Isolation of Nocardia from clinical specimens and identification of species is difficult and needs the expertise of a microbiologist. These infections are particularly important because of the associated high risk of dissemination. Hence, prompt identification of this organism is crucial. Herein we report a case of disseminated nocardiosis caused by N. brasiliensis in a 64-year-old man diagnosed by fine needle aspiration (FNA) and 16S ribosomal RNA sequencing. The patient was treated with trimethoprim plus sulfamethoxazole, imipenem, and amikacin with an improvement of symptoms.

Original languageEnglish
Pages (from-to)1024-1028
Number of pages5
JournalKorean Journal of Dermatology
Volume47
Issue number9
Publication statusPublished - 2009 Sep

All Science Journal Classification (ASJC) codes

  • Dermatology

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