A case of Graves' disease coexistent with pulmonary sarcoidosis

Won Jo Ki, Hyun Koh Jang, Young Lee Mi, Moon Jung Feel, Goo Shin Young, Joong Yong Suk, Hee Chung Choon

Research output: Contribution to journalReview articlepeer-review


Sarcoidosis is a multisystemic granulomatous disease with an of unknown etiology, involving bilateral hilar lymphadenopathy, pulmonary, skin and eye lesions. However, involvement of the endocrine system in sarcoidosis is quite rare, and the coexistence of both diseases is extremely unusual. We describe a 60-year-old woman presenting with sarcoidosis and Graves' disease. She was admitted for evaluation of dry cough, dyspnea, palpitation and general weakness. Both thyroid glands were enlarged diffusely. The thyroid function tests showed suppressed serum thyrotropin and an increased thyroid hormone level. The levels of the TSH receptor antibody, anti-thyroglobulin antibody and anti-microsomal antibody were higher than normal. The radionuclide scan(131I) showed increased iodine uptake. The chest X-ray revealed pulmonary hilar enlargement and high resolution CT showed both hilar lymph nodes enlargement and tiny parenchymal nodules. The transbronchial lung biopsy showed a noncaseating granuloma without necrosis. We report this case of pulmonary sarcoidosis plus Graves' disease with a review of the relevant literatures.

Original languageEnglish
Pages (from-to)417-420
Number of pages4
JournalTuberculosis and Respiratory Diseases
Issue number5
Publication statusPublished - 2007 May

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases


Dive into the research topics of 'A case of Graves' disease coexistent with pulmonary sarcoidosis'. Together they form a unique fingerprint.

Cite this