A case of melioidosis presenting as migrating pulmonary infiltration: The first case in Korea

Won Lee Sei, Jongyoun Yi, Sae Ik Joo, Ae Kang Young, Soon Yoon Young, Jae Joon Yim, Chul Gyu Yoo, Koo Han Sung, Young Soo Shim, Eui Chong Kim, Whan Kim Young

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Abstract

Melioidosis is an infection of the Gram-negative bacterium Burkholderia pseudomallei. While it is known as an important cause of sepsis or chronic abscess-forming disease in Southeast Asia and northern Australia, no case has yet been reported in Korea. A 50-yr-old man visited our hospital for intermittent fever associated with dry cough and sputum. Roentgenographic examination showed migrating pulmonary infiltration. Symptoms and chest radiograph and computed tomography (CT) image findings did not improve despite use of fluoroquinolone antibiotics. Gram-negative bacteria were isolated on bronchoscopic washing culture and were identified as B. pseudomallei on DNA sequencing of 16S ribosomal RNA with 100% homology. Treatment for melioidosis was commenced with high dose ceftazidime, and the patient's fever, cough, and sputum were improved and the lesion on chest radiograph and CT almost disappeared.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalJournal of Korean medical science
Volume20
Issue number1
DOIs
Publication statusPublished - 2005 Feb

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Sei, W. L., Yi, J., Joo, S. I., Young, A. K., Young, S. Y., Yim, J. J., Yoo, C. G., Sung, K. H., Shim, Y. S., Kim, E. C., & Young, W. K. (2005). A case of melioidosis presenting as migrating pulmonary infiltration: The first case in Korea. Journal of Korean medical science, 20(1), 139-142. https://doi.org/10.3346/jkms.2005.20.1.139