A case of pneumonia with septic shock due to Nocardia farcinia in liver transplant patient

Su Hwan Lee, Byung Hoon Park, Ji Young Son, Ji Ye Jung, Eun Young Kim, Ju Eun Lim, Ji Hoon Lee, Shin Young Hyun, Sang Hoon Lee, Sang Kook Lee, Song Yee Kim, Kyung Jong Lee, youngae kang, Young Sam Kim, Se Kyu Kim, Joon Chang, You Kyung Seo, Kyungwon Lee, Moo Suk Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Nocardia farcinia, an aerobic, gram-positive bacilli actinomycetes of the genus Nocardia, is an uncommon pathogen found in humans. The most common Nocardia infection sites are the lung, central nervous system, and skin. Even though hematogenous dissemination can occur, isolation of the organism from blood cultures is very rare. We report a case of Nocardia infection that was isolated on blood cultures. A 59-year-old male with a medical history that includes a liver transplantation 6-years prior due to hepatocellular carcinoma secondary to chronic hepatitis B, developed pneumonia and was transferred to Severance Hospital. At the time of admission, the patient's initial exam showed hypothermia, tachypnea, and hypotension. His chest radiograph showed severe pneumonia and a large abscess on left upper lobe. Under the presumptive diagnosis of bacterial pneumonia or other opportunistic infection, we started broad spectrum antibiotics. However, he developed Nocardia sepsis, rapidly deteriorated, and subsequently died. Copyright

Original languageEnglish
Pages (from-to)469-473
Number of pages5
JournalTuberculosis and Respiratory Diseases
Volume69
Issue number6
DOIs
Publication statusPublished - 2010 Dec 1

Fingerprint

Nocardia
Septic Shock
Nocardia Infections
Pneumonia
Transplants
Liver
Tachypnea
Bacterial Pneumonia
Actinobacteria
Patient Admission
Opportunistic Infections
Chronic Hepatitis B
Hypothermia
Liver Transplantation
Hypotension
Abscess
Bacillus
Hepatocellular Carcinoma
Sepsis
Thorax

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

Cite this

Lee, S. H., Park, B. H., Son, J. Y., Jung, J. Y., Kim, E. Y., Lim, J. E., ... Park, M. S. (2010). A case of pneumonia with septic shock due to Nocardia farcinia in liver transplant patient. Tuberculosis and Respiratory Diseases, 69(6), 469-473. https://doi.org/10.4046/trd.2010.69.6.469
Lee, Su Hwan ; Park, Byung Hoon ; Son, Ji Young ; Jung, Ji Ye ; Kim, Eun Young ; Lim, Ju Eun ; Lee, Ji Hoon ; Hyun, Shin Young ; Lee, Sang Hoon ; Lee, Sang Kook ; Kim, Song Yee ; Lee, Kyung Jong ; kang, youngae ; Kim, Young Sam ; Kim, Se Kyu ; Chang, Joon ; Seo, You Kyung ; Lee, Kyungwon ; Park, Moo Suk. / A case of pneumonia with septic shock due to Nocardia farcinia in liver transplant patient. In: Tuberculosis and Respiratory Diseases. 2010 ; Vol. 69, No. 6. pp. 469-473.
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abstract = "Nocardia farcinia, an aerobic, gram-positive bacilli actinomycetes of the genus Nocardia, is an uncommon pathogen found in humans. The most common Nocardia infection sites are the lung, central nervous system, and skin. Even though hematogenous dissemination can occur, isolation of the organism from blood cultures is very rare. We report a case of Nocardia infection that was isolated on blood cultures. A 59-year-old male with a medical history that includes a liver transplantation 6-years prior due to hepatocellular carcinoma secondary to chronic hepatitis B, developed pneumonia and was transferred to Severance Hospital. At the time of admission, the patient's initial exam showed hypothermia, tachypnea, and hypotension. His chest radiograph showed severe pneumonia and a large abscess on left upper lobe. Under the presumptive diagnosis of bacterial pneumonia or other opportunistic infection, we started broad spectrum antibiotics. However, he developed Nocardia sepsis, rapidly deteriorated, and subsequently died. Copyright",
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Lee, SH, Park, BH, Son, JY, Jung, JY, Kim, EY, Lim, JE, Lee, JH, Hyun, SY, Lee, SH, Lee, SK, Kim, SY, Lee, KJ, kang, Y, Kim, YS, Kim, SK, Chang, J, Seo, YK, Lee, K & Park, MS 2010, 'A case of pneumonia with septic shock due to Nocardia farcinia in liver transplant patient', Tuberculosis and Respiratory Diseases, vol. 69, no. 6, pp. 469-473. https://doi.org/10.4046/trd.2010.69.6.469

A case of pneumonia with septic shock due to Nocardia farcinia in liver transplant patient. / Lee, Su Hwan; Park, Byung Hoon; Son, Ji Young; Jung, Ji Ye; Kim, Eun Young; Lim, Ju Eun; Lee, Ji Hoon; Hyun, Shin Young; Lee, Sang Hoon; Lee, Sang Kook; Kim, Song Yee; Lee, Kyung Jong; kang, youngae; Kim, Young Sam; Kim, Se Kyu; Chang, Joon; Seo, You Kyung; Lee, Kyungwon; Park, Moo Suk.

In: Tuberculosis and Respiratory Diseases, Vol. 69, No. 6, 01.12.2010, p. 469-473.

Research output: Contribution to journalArticle

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T1 - A case of pneumonia with septic shock due to Nocardia farcinia in liver transplant patient

AU - Lee, Su Hwan

AU - Park, Byung Hoon

AU - Son, Ji Young

AU - Jung, Ji Ye

AU - Kim, Eun Young

AU - Lim, Ju Eun

AU - Lee, Ji Hoon

AU - Hyun, Shin Young

AU - Lee, Sang Hoon

AU - Lee, Sang Kook

AU - Kim, Song Yee

AU - Lee, Kyung Jong

AU - kang, youngae

AU - Kim, Young Sam

AU - Kim, Se Kyu

AU - Chang, Joon

AU - Seo, You Kyung

AU - Lee, Kyungwon

AU - Park, Moo Suk

PY - 2010/12/1

Y1 - 2010/12/1

N2 - Nocardia farcinia, an aerobic, gram-positive bacilli actinomycetes of the genus Nocardia, is an uncommon pathogen found in humans. The most common Nocardia infection sites are the lung, central nervous system, and skin. Even though hematogenous dissemination can occur, isolation of the organism from blood cultures is very rare. We report a case of Nocardia infection that was isolated on blood cultures. A 59-year-old male with a medical history that includes a liver transplantation 6-years prior due to hepatocellular carcinoma secondary to chronic hepatitis B, developed pneumonia and was transferred to Severance Hospital. At the time of admission, the patient's initial exam showed hypothermia, tachypnea, and hypotension. His chest radiograph showed severe pneumonia and a large abscess on left upper lobe. Under the presumptive diagnosis of bacterial pneumonia or other opportunistic infection, we started broad spectrum antibiotics. However, he developed Nocardia sepsis, rapidly deteriorated, and subsequently died. Copyright

AB - Nocardia farcinia, an aerobic, gram-positive bacilli actinomycetes of the genus Nocardia, is an uncommon pathogen found in humans. The most common Nocardia infection sites are the lung, central nervous system, and skin. Even though hematogenous dissemination can occur, isolation of the organism from blood cultures is very rare. We report a case of Nocardia infection that was isolated on blood cultures. A 59-year-old male with a medical history that includes a liver transplantation 6-years prior due to hepatocellular carcinoma secondary to chronic hepatitis B, developed pneumonia and was transferred to Severance Hospital. At the time of admission, the patient's initial exam showed hypothermia, tachypnea, and hypotension. His chest radiograph showed severe pneumonia and a large abscess on left upper lobe. Under the presumptive diagnosis of bacterial pneumonia or other opportunistic infection, we started broad spectrum antibiotics. However, he developed Nocardia sepsis, rapidly deteriorated, and subsequently died. Copyright

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