A case report of xanthogranulomatous osteomyelitis of the distal ulna mimicking a malignant neoplasm

Seung Hyun Lee, Young Han Lee, Heejung Park, Yong Jin Cho, Ho Taek Song, Woo Ik Yang, Jin Suck Suh

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Objective: Rare disease Background: Xanthogranulomatous inflammation is a chronic inflammatory disease in which bone involvement is extremely rare. Bone involvement of xanthogranulomatous inflammation, termed xanthogranulomatous osteomyelitis (XO), often presents as a mass-like lesion extending to adjacent structures, which can mimic infiltrative carcinoma. Case Report: We present a case of XO in the ulna, which mimicked a neoplasm. A 59-year-old man presented with a 2-month history of painful swelling in the right wrist. Plain radiography and CT showed an osteolytic lesion at the distal ulna. MRI revealed a soft-tissue mass with lobulated margins and contrast enhancement. Intense uptake in bone scan and PET suggested malignancy. An excisional biopsy from the representative area resulted in a pathology diagnosis of XO. Conclusions: Gross and radiologic manifestations of XO can mimic neoplasm. XO generally has benign prognosis, contrary to malignant bone tumor. Therefore, biopsy and histopathological confirmation are necessary for proper management.

Original languageEnglish
Pages (from-to)304-307
Number of pages4
JournalAmerican Journal of Case Reports
Publication statusPublished - 2013 Aug 9


All Science Journal Classification (ASJC) codes

  • Medicine(all)

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