Abstract
Z for zinc and Z-DNA: As a result of different binding modes, a cationic zinc porphyrin discriminates between B and Z conformations of DNA and holds promise as a probe for Z-DNA. A very intense induced circular dichroism (ICD) effect with a bisignate spectrum is observed upon interaction of the porphyrin with Z-DNA (see graphic; porphyrin red, Z-DNA green), whereas only a weak ICD spectrum results upon its interaction with B-DNA (Figure Presented).
| Original language | English |
|---|---|
| Pages (from-to) | 4006-4009 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 44 |
| Issue number | 26 |
| DOIs | |
| Publication status | Published - 2005 Jun 27 |
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All Science Journal Classification (ASJC) codes
- Catalysis
- Chemistry(all)
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A cationic zinc porphyrin as a chiroptical probe for Z-DNA. / Balaz, Milan; De Napoli, Massimo; Holmes, Andrea E.; Mammana, Angela; Nakanishi, Koji; Berova, Nina; Purrello, Roberto.
In: Angewandte Chemie - International Edition, Vol. 44, No. 26, 27.06.2005, p. 4006-4009.Research output: Contribution to journal › Article
TY - JOUR
T1 - A cationic zinc porphyrin as a chiroptical probe for Z-DNA
AU - Balaz, Milan
AU - De Napoli, Massimo
AU - Holmes, Andrea E.
AU - Mammana, Angela
AU - Nakanishi, Koji
AU - Berova, Nina
AU - Purrello, Roberto
PY - 2005/6/27
Y1 - 2005/6/27
N2 - Z for zinc and Z-DNA: As a result of different binding modes, a cationic zinc porphyrin discriminates between B and Z conformations of DNA and holds promise as a probe for Z-DNA. A very intense induced circular dichroism (ICD) effect with a bisignate spectrum is observed upon interaction of the porphyrin with Z-DNA (see graphic; porphyrin red, Z-DNA green), whereas only a weak ICD spectrum results upon its interaction with B-DNA (Figure Presented).
AB - Z for zinc and Z-DNA: As a result of different binding modes, a cationic zinc porphyrin discriminates between B and Z conformations of DNA and holds promise as a probe for Z-DNA. A very intense induced circular dichroism (ICD) effect with a bisignate spectrum is observed upon interaction of the porphyrin with Z-DNA (see graphic; porphyrin red, Z-DNA green), whereas only a weak ICD spectrum results upon its interaction with B-DNA (Figure Presented).
UR - http://www.scopus.com/inward/record.url?scp=21244490493&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=21244490493&partnerID=8YFLogxK
U2 - 10.1002/anie.200501149
DO - 10.1002/anie.200501149
M3 - Article
C2 - 15915533
AN - SCOPUS:21244490493
VL - 44
SP - 4006
EP - 4009
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 26
ER -