A clinical and histopathological study of 22 patients with membranous lipodystrophy

S. Ahn, M. Yoo, S. Lee, E. Choi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Membranous lipodystrophy, an uncommon disorder, was described by Nasu et al. in 1973 as a form of regressive degeneration or localized destruction of the adipose tissue. Clinical features of the lesions with membranous fat necrosis are variable and the condition can only be diagnosed histopathologically. These peculiar changes in fat tissue have been associated with many local and systemic diseases including lupus erythematosus, diabetes mellitus, erythema nodosum, stasis dermatitis, morphoea and trauma, but occasionally no underlying disease is found. Even though various hypotheses concerning the pathogenesis of membranous lipodystrophy have been proposed, the exact causes are still in dispute. We reviewed 22 patients having membranous lipodystrophy confirmed by biopsy and discuss the pathogenetic mechanisms which have been suggested by many authors.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
JournalClinical and Experimental Dermatology
Volume21
Issue number4
DOIs
Publication statusPublished - 1996 Nov 23

Fingerprint

Lipodystrophy
Fat Necrosis
Localized Scleroderma
Erythema Nodosum
Dissent and Disputes
Dermatitis
Adipose Tissue
Diabetes Mellitus
Fats
Biopsy
Wounds and Injuries
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

@article{9791b5d761ec4a1bae7a65a2ec7feda9,
title = "A clinical and histopathological study of 22 patients with membranous lipodystrophy",
abstract = "Membranous lipodystrophy, an uncommon disorder, was described by Nasu et al. in 1973 as a form of regressive degeneration or localized destruction of the adipose tissue. Clinical features of the lesions with membranous fat necrosis are variable and the condition can only be diagnosed histopathologically. These peculiar changes in fat tissue have been associated with many local and systemic diseases including lupus erythematosus, diabetes mellitus, erythema nodosum, stasis dermatitis, morphoea and trauma, but occasionally no underlying disease is found. Even though various hypotheses concerning the pathogenesis of membranous lipodystrophy have been proposed, the exact causes are still in dispute. We reviewed 22 patients having membranous lipodystrophy confirmed by biopsy and discuss the pathogenetic mechanisms which have been suggested by many authors.",
author = "S. Ahn and M. Yoo and S. Lee and E. Choi",
year = "1996",
month = "11",
day = "23",
doi = "10.1111/j.1365-2230.1996.tb00091.x",
language = "English",
volume = "21",
pages = "269--272",
journal = "Clinical and Experimental Dermatology",
issn = "0307-6938",
publisher = "Wiley-Blackwell",
number = "4",

}

A clinical and histopathological study of 22 patients with membranous lipodystrophy. / Ahn, S.; Yoo, M.; Lee, S.; Choi, E.

In: Clinical and Experimental Dermatology, Vol. 21, No. 4, 23.11.1996, p. 269-272.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A clinical and histopathological study of 22 patients with membranous lipodystrophy

AU - Ahn, S.

AU - Yoo, M.

AU - Lee, S.

AU - Choi, E.

PY - 1996/11/23

Y1 - 1996/11/23

N2 - Membranous lipodystrophy, an uncommon disorder, was described by Nasu et al. in 1973 as a form of regressive degeneration or localized destruction of the adipose tissue. Clinical features of the lesions with membranous fat necrosis are variable and the condition can only be diagnosed histopathologically. These peculiar changes in fat tissue have been associated with many local and systemic diseases including lupus erythematosus, diabetes mellitus, erythema nodosum, stasis dermatitis, morphoea and trauma, but occasionally no underlying disease is found. Even though various hypotheses concerning the pathogenesis of membranous lipodystrophy have been proposed, the exact causes are still in dispute. We reviewed 22 patients having membranous lipodystrophy confirmed by biopsy and discuss the pathogenetic mechanisms which have been suggested by many authors.

AB - Membranous lipodystrophy, an uncommon disorder, was described by Nasu et al. in 1973 as a form of regressive degeneration or localized destruction of the adipose tissue. Clinical features of the lesions with membranous fat necrosis are variable and the condition can only be diagnosed histopathologically. These peculiar changes in fat tissue have been associated with many local and systemic diseases including lupus erythematosus, diabetes mellitus, erythema nodosum, stasis dermatitis, morphoea and trauma, but occasionally no underlying disease is found. Even though various hypotheses concerning the pathogenesis of membranous lipodystrophy have been proposed, the exact causes are still in dispute. We reviewed 22 patients having membranous lipodystrophy confirmed by biopsy and discuss the pathogenetic mechanisms which have been suggested by many authors.

UR - http://www.scopus.com/inward/record.url?scp=0029836865&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029836865&partnerID=8YFLogxK

U2 - 10.1111/j.1365-2230.1996.tb00091.x

DO - 10.1111/j.1365-2230.1996.tb00091.x

M3 - Article

C2 - 8959896

AN - SCOPUS:0029836865

VL - 21

SP - 269

EP - 272

JO - Clinical and Experimental Dermatology

JF - Clinical and Experimental Dermatology

SN - 0307-6938

IS - 4

ER -