A concise synthesis of (-)-cytoxazone

Van Thoai Pham, Jae Eun Joo, Yong Shou Tian, Yong Hyun Kim, Kee Young Lee, Chang Young Oh, Jin Hyun Jeong, Won Hun Ham

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

A concise, stereoselective synthesis of (-)-cytoxazone 1 was described. A key feature is highly diastereoselective reduction of the amino ketone to give the anti-amino alcohol directly, which is 2-oxazolidinone precursor.

Original languageEnglish
Pages (from-to)2817-2823
Number of pages7
JournalHeterocycles
Volume75
Issue number11
DOIs
Publication statusPublished - 2008 Dec 1

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Amino Alcohols
Oxazolidinones
Ketones
cytoxazone

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Cite this

Pham, V. T., Joo, J. E., Tian, Y. S., Kim, Y. H., Lee, K. Y., Oh, C. Y., ... Ham, W. H. (2008). A concise synthesis of (-)-cytoxazone. Heterocycles, 75(11), 2817-2823. https://doi.org/10.3987/COM-08-11446
Pham, Van Thoai ; Joo, Jae Eun ; Tian, Yong Shou ; Kim, Yong Hyun ; Lee, Kee Young ; Oh, Chang Young ; Jeong, Jin Hyun ; Ham, Won Hun. / A concise synthesis of (-)-cytoxazone. In: Heterocycles. 2008 ; Vol. 75, No. 11. pp. 2817-2823.
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Pham, VT, Joo, JE, Tian, YS, Kim, YH, Lee, KY, Oh, CY, Jeong, JH & Ham, WH 2008, 'A concise synthesis of (-)-cytoxazone', Heterocycles, vol. 75, no. 11, pp. 2817-2823. https://doi.org/10.3987/COM-08-11446

A concise synthesis of (-)-cytoxazone. / Pham, Van Thoai; Joo, Jae Eun; Tian, Yong Shou; Kim, Yong Hyun; Lee, Kee Young; Oh, Chang Young; Jeong, Jin Hyun; Ham, Won Hun.

In: Heterocycles, Vol. 75, No. 11, 01.12.2008, p. 2817-2823.

Research output: Contribution to journalReview article

TY - JOUR

T1 - A concise synthesis of (-)-cytoxazone

AU - Pham, Van Thoai

AU - Joo, Jae Eun

AU - Tian, Yong Shou

AU - Kim, Yong Hyun

AU - Lee, Kee Young

AU - Oh, Chang Young

AU - Jeong, Jin Hyun

AU - Ham, Won Hun

PY - 2008/12/1

Y1 - 2008/12/1

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AB - A concise, stereoselective synthesis of (-)-cytoxazone 1 was described. A key feature is highly diastereoselective reduction of the amino ketone to give the anti-amino alcohol directly, which is 2-oxazolidinone precursor.

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DO - 10.3987/COM-08-11446

M3 - Review article

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JO - Heterocycles

JF - Heterocycles

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Pham VT, Joo JE, Tian YS, Kim YH, Lee KY, Oh CY et al. A concise synthesis of (-)-cytoxazone. Heterocycles. 2008 Dec 1;75(11):2817-2823. https://doi.org/10.3987/COM-08-11446