A concise synthesis of (-)-cytoxazone

Van Thoai Pham, Jae Eun Joo, Yong Shou Tian, Yong Hyun Kim, Kee Young Lee, Chang Young Oh, Jin Hyun Jeong, Won Hun Ham

Research output: Contribution to journalReview article

3 Citations (Scopus)


A concise, stereoselective synthesis of (-)-cytoxazone 1 was described. A key feature is highly diastereoselective reduction of the amino ketone to give the anti-amino alcohol directly, which is 2-oxazolidinone precursor.

Original languageEnglish
Pages (from-to)2817-2823
Number of pages7
Issue number11
Publication statusPublished - 2008 Dec 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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    Pham, V. T., Joo, J. E., Tian, Y. S., Kim, Y. H., Lee, K. Y., Oh, C. Y., Jeong, J. H., & Ham, W. H. (2008). A concise synthesis of (-)-cytoxazone. Heterocycles, 75(11), 2817-2823. https://doi.org/10.3987/COM-08-11446