Abstract
A process to prepare microparticles of narrow size distribution having a particle size in the range of approximately 1-8 μm was developed. The primary objective of this work was to study the formation and morphology of copolyester microparticles prepared using a sulfonated copolyester emulsion by an emulsion-aggregation process. Molecular weight of the copolyesters was measured by gel permeation chromatography. The glass transition temperature (Tg) of the copolyesters was found to be in the range of 40-70 °C. Aggregating agents used in this study were 1-5% (wt.%) solutions of divalent ions of zinc acetate and magnesium chloride salts. Emulsion-aggregation experiments were performed at various temperatures: 40, 50, 60, and 80 °C. Particle morphologies studied by field emission-scanning electron microscopy measurements provided an understanding of the conditions and mechanism leading to formation of microparticles by the emulsion-aggregation process. Molecular weight and Tg of the copolyester, the concentration of aggregating agent, and the temperature were determined to be the most important parameters influencing the preparation of microparticles. This process illustrates the preparation of microparticles of uniform size with morphology of controlled shape from a nanometer-sized emulsion by ionic crosslinking.
| Original language | English |
|---|---|
| Pages (from-to) | 40-49 |
| Number of pages | 10 |
| Journal | Colloids and Surfaces A: Physicochemical and Engineering Aspects |
| Volume | 340 |
| Issue number | 1-3 |
| DOIs | |
| Publication status | Published - 2009 May 15 |
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All Science Journal Classification (ASJC) codes
- Surfaces and Interfaces
- Physical and Theoretical Chemistry
- Colloid and Surface Chemistry
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A facile preparation of microparticles from sulfonated polyester nanoparticles via emulsion-aggregation process. / Subramani, Sankaraiah; Lee, Sun Jong; Lee, Jung Min; Choi, Sung Wook; Kim, Jung-Hyun.
In: Colloids and Surfaces A: Physicochemical and Engineering Aspects, Vol. 340, No. 1-3, 15.05.2009, p. 40-49.Research output: Contribution to journal › Article
TY - JOUR
T1 - A facile preparation of microparticles from sulfonated polyester nanoparticles via emulsion-aggregation process
AU - Subramani, Sankaraiah
AU - Lee, Sun Jong
AU - Lee, Jung Min
AU - Choi, Sung Wook
AU - Kim, Jung-Hyun
PY - 2009/5/15
Y1 - 2009/5/15
N2 - A process to prepare microparticles of narrow size distribution having a particle size in the range of approximately 1-8 μm was developed. The primary objective of this work was to study the formation and morphology of copolyester microparticles prepared using a sulfonated copolyester emulsion by an emulsion-aggregation process. Molecular weight of the copolyesters was measured by gel permeation chromatography. The glass transition temperature (Tg) of the copolyesters was found to be in the range of 40-70 °C. Aggregating agents used in this study were 1-5% (wt.%) solutions of divalent ions of zinc acetate and magnesium chloride salts. Emulsion-aggregation experiments were performed at various temperatures: 40, 50, 60, and 80 °C. Particle morphologies studied by field emission-scanning electron microscopy measurements provided an understanding of the conditions and mechanism leading to formation of microparticles by the emulsion-aggregation process. Molecular weight and Tg of the copolyester, the concentration of aggregating agent, and the temperature were determined to be the most important parameters influencing the preparation of microparticles. This process illustrates the preparation of microparticles of uniform size with morphology of controlled shape from a nanometer-sized emulsion by ionic crosslinking.
AB - A process to prepare microparticles of narrow size distribution having a particle size in the range of approximately 1-8 μm was developed. The primary objective of this work was to study the formation and morphology of copolyester microparticles prepared using a sulfonated copolyester emulsion by an emulsion-aggregation process. Molecular weight of the copolyesters was measured by gel permeation chromatography. The glass transition temperature (Tg) of the copolyesters was found to be in the range of 40-70 °C. Aggregating agents used in this study were 1-5% (wt.%) solutions of divalent ions of zinc acetate and magnesium chloride salts. Emulsion-aggregation experiments were performed at various temperatures: 40, 50, 60, and 80 °C. Particle morphologies studied by field emission-scanning electron microscopy measurements provided an understanding of the conditions and mechanism leading to formation of microparticles by the emulsion-aggregation process. Molecular weight and Tg of the copolyester, the concentration of aggregating agent, and the temperature were determined to be the most important parameters influencing the preparation of microparticles. This process illustrates the preparation of microparticles of uniform size with morphology of controlled shape from a nanometer-sized emulsion by ionic crosslinking.
UR - http://www.scopus.com/inward/record.url?scp=64849100762&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=64849100762&partnerID=8YFLogxK
U2 - 10.1016/j.colsurfa.2009.02.037
DO - 10.1016/j.colsurfa.2009.02.037
M3 - Article
VL - 340
SP - 40
EP - 49
JO - Colloids and Surfaces A: Physicochemical and Engineering Aspects
JF - Colloids and Surfaces A: Physicochemical and Engineering Aspects
SN - 0927-7757
IS - 1-3
ER -