A flexible fish-bone-shaped neural probe strengthened by biodegradable silk coating for enhanced biocompatibility

Fan Wu, Maesoon Im, Euisik Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

39 Citations (Scopus)

Abstract

This paper reports a fish-bone-shaped polyimide neural probe for chronic recording applications. This unique design aims to minimize tissue reaction by having flexible substrate, small dimensions, large separation distance between electrodes and the probe shank, as well as large substrate openings. A biodegradable silk polymer is coated around the polyimide structure to provide temporary mechanical strength during insertion. The time required for the complete degradation of silk can be controlled within the range of 30 minutes to 25 hours by water annealing process. In-vitro insertion of the fabricated silk-coated probe into brain tissue has been successfully demonstrated.

Original languageEnglish
Title of host publication2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages966-969
Number of pages4
DOIs
Publication statusPublished - 2011
Event2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China
Duration: 2011 Jun 52011 Jun 9

Publication series

Name2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Other

Other2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
CountryChina
CityBeijing
Period11/6/511/6/9

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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    Wu, F., Im, M., & Yoon, E. (2011). A flexible fish-bone-shaped neural probe strengthened by biodegradable silk coating for enhanced biocompatibility. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 (pp. 966-969). [5969356] (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11). https://doi.org/10.1109/TRANSDUCERS.2011.5969356