A goid(III) ion-Selective fluorescent probe and its application to bioimagings

Young Keun Yang; Sunho Lee; Jinsung Tae

doi:10.1021/ol902325u

A goid(III) ion-Selective fluorescent probe and its application to bioimagings

Young Keun Yang, Sunho Lee, Jinsung Tae

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

124 Citations (Scopus)

Abstract

[Chemical Equation Presented] A highly selective and sensitive fluorescent chemosensor for Au³⁺ has been reported. The system utilizes an irreversible Au³⁺-promoted cyclization reaction of a rhodamine amide tethered with an alkyne. The probe can sense Au³⁺ ions selectively over other biologically relevant metal ions, and ∼50 nM of Au³⁺ could be readily detected in aqueous media. Fluorescent imaging of Au ³⁺ in living cells Is also successfully demonstrated.

Original language	English
Pages (from-to)	5610-5613
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	24
DOIs	https://doi.org/10.1021/ol902325u
Publication status	Published - 2009 Dec 17

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol902325u

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abstract = "[Chemical Equation Presented] A highly selective and sensitive fluorescent chemosensor for Au3+ has been reported. The system utilizes an irreversible Au3+-promoted cyclization reaction of a rhodamine amide tethered with an alkyne. The probe can sense Au3+ ions selectively over other biologically relevant metal ions, and ∼50 nM of Au3+ could be readily detected in aqueous media. Fluorescent imaging of Au 3+ in living cells Is also successfully demonstrated.",

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AB - [Chemical Equation Presented] A highly selective and sensitive fluorescent chemosensor for Au3+ has been reported. The system utilizes an irreversible Au3+-promoted cyclization reaction of a rhodamine amide tethered with an alkyne. The probe can sense Au3+ ions selectively over other biologically relevant metal ions, and ∼50 nM of Au3+ could be readily detected in aqueous media. Fluorescent imaging of Au 3+ in living cells Is also successfully demonstrated.

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A goid(III) ion-Selective fluorescent probe and its application to bioimagings

Abstract

All Science Journal Classification (ASJC) codes

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