A hydrazide organogelator for fluoride sensing with hyperchromicity and gel-to-sol transition

Sangwoo Park, Jeewon Ju, Young Ju Lee, Sang Yup Lee

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7 Citations (Scopus)


Sensing of fluoride in a solvent is highly required in healthcare and environmental rehabilitation. Among the various sensing methods, optical sensing has attracted significant research interest because it can conveniently recognize fluoride. Herein, a low molecular weight organogelator, N′1,N′6-bis(3-(1-pyrrolyl)propanoyl) hexanedihydrazide (DPH), containing a central butyl chain conjugated to two pyrrole rings through hydrazide groups, was used for optical sensing of fluoride in the forms of both solution and organogel. Association of fluoride with the -NH moiety of the hydrazide group endowed the DPH solution in dimethylformamide with a hyperchromicity under 350 nm. Exploiting the UV absorptivity, the DPH solution was examined as a chemosensor, displaying good selectivity toward fluoride among various anions and moderate sensitivity with a detection limit of 0.49 μM. The practical use of the DPH solution was demonstrated for fluoride sensing in toothpaste. Binding of fluoride also changed the molecular interactions of the DPH organogel, resulting in a phase transition from gel to sol. This gel-to-sol transition enabled the sensing of fluoride by the naked eye.

Original languageEnglish
Pages (from-to)14243-14248
Number of pages6
JournalRSC Advances
Issue number24
Publication statusPublished - 2020 Apr 8

Bibliographical note

Funding Information:
This study was supported by a grant from the Korean Research Foundation funded by the Korean Government (NRF-2019R1A2C1010629) and Human Resources Program in Energy Technology of the Korea Institute of Energy Technology Evaluation and Planning (KETEP), funded Trade, Industry & Energy, Republic 20154010200810).

Publisher Copyright:
© 2020 The Royal Society of Chemistry.

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)


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