A Meta-Analysis of Nonpharmacological Interventions for People With Parkinson’s Disease

Juhee Lee, Moon Ki Choi, Yonju Yoo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Nonpharmacological interventions are important in providing care for Parkinson’s disease (PD) patients. However, there is limited evidence related to their impacts on health-related quality of life (HRQOL). We aimed to examine the effectiveness of nonpharmacological interventions for improving the HRQOL of PD patients. Articles published in peer-reviewed journals from 2000 to 2015 were searched through electronic searching, computerized author searching, and footnote chasing. A meta-analysis was performed using the RevMan 5.3 program. Overall, effect size for the studies (n = 18) was −4.17 with 95% confidence interval (CI) from −7.63 to −0.70 (Z = 2.36, p =.02), indicating positive effects of nonpharmacological interventions on HRQOL. In subgroup analysis regarding the intervention types, the effect size of exercise programs was −5.73 with 95% CI of −11.36 to −0.10 (Z = 2.00, p =.05). Thus, nonpharmacological interventions, and particularly exercise programs, were effective in improving the HRQOL of PD patients.

Original languageEnglish
Pages (from-to)608-631
Number of pages24
JournalClinical Nursing Research
Volume26
Issue number5
DOIs
Publication statusPublished - 2017 Oct 1

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Parkinson Disease
Meta-Analysis
Quality of Life
Confidence Intervals
Exercise

All Science Journal Classification (ASJC) codes

  • Nursing(all)

Cite this

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abstract = "Nonpharmacological interventions are important in providing care for Parkinson’s disease (PD) patients. However, there is limited evidence related to their impacts on health-related quality of life (HRQOL). We aimed to examine the effectiveness of nonpharmacological interventions for improving the HRQOL of PD patients. Articles published in peer-reviewed journals from 2000 to 2015 were searched through electronic searching, computerized author searching, and footnote chasing. A meta-analysis was performed using the RevMan 5.3 program. Overall, effect size for the studies (n = 18) was −4.17 with 95{\%} confidence interval (CI) from −7.63 to −0.70 (Z = 2.36, p =.02), indicating positive effects of nonpharmacological interventions on HRQOL. In subgroup analysis regarding the intervention types, the effect size of exercise programs was −5.73 with 95{\%} CI of −11.36 to −0.10 (Z = 2.00, p =.05). Thus, nonpharmacological interventions, and particularly exercise programs, were effective in improving the HRQOL of PD patients.",
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A Meta-Analysis of Nonpharmacological Interventions for People With Parkinson’s Disease. / Lee, Juhee; Choi, Moon Ki; Yoo, Yonju.

In: Clinical Nursing Research, Vol. 26, No. 5, 01.10.2017, p. 608-631.

Research output: Contribution to journalArticle

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