A method for the synthesis of pyridines from aldehydes, alkynes and NH4OAc involving Rh-catalyzed hydroacylation andN-annulation

Yong Kyun Sim, Hyejeong Lee, Jung Woo Park, Dong Su Kim, Chul Ho Jun

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A new method for regiocontrolled pyridine synthesis has been developed involving sequential Rh(i)-catalyzed chelation-assisted hydroacylation of alkynes with aldehydes followed by Rh(iii)-promotedN-annulation of the resulting α,β-enones with another alkyne and NH3.

Original languageEnglish
Pages (from-to)11787-11789
Number of pages3
JournalChemical Communications
Issue number96
Publication statusPublished - 2012 Nov 7


All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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