A mild and efficient procedure for the preparation of acid chlorides from carboxylic acids

Doo Ok Jang, Doo Jin Park, Kim Joonggon

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Various carboxylic acids are converted into the corresponding acid chlorides by treatment with trichloroacetonitrile and triphenylphosphine in methylene chloride at room temperature. Aryl acids show higher reactivity than alkyl acids under the conditions.

Original languageEnglish
Pages (from-to)5323-5326
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number29
DOIs
Publication statusPublished - 1999 Jul 16

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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