A multi-source inverse-geometry CT system: Initial results with an 8 spot x-ray source array

Jongduk Baek, Bruno De Man, Jorge Uribe, Randy Longtin, Daniel Harrison, Joseph Reynolds, Bogdan Neculaes, Kristopher Frutschy, Louis Inzinna, Antonio Caiafa, Robert Senzig, Norbert J. Pelc

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We present initial experimental results of a rotating-gantry multi-source inverse-geometry CT (MS-IGCT) system. The MS-IGCT system was built with a single module of 2 × 4 x-ray sources and a 2D detector array. It produced a 75 mm in-plane field-of-view (FOV) with 160 mm axial coverage in a single gantry rotation. To evaluate system performance, a 2.5 inch diameter uniform PMMA cylinder phantom, a 200 μm diameter tungsten wire, and a euthanized rat were scanned. Each scan acquired 125 views per source and the gantry rotation time was 1 s per revolution. Geometric calibration was performed using a bead phantom. The scanning parameters were 80 kVp, 125 mA, and 5.4 μs pulse per source location per view. A data normalization technique was applied to the acquired projection data, and beam hardening and spectral nonlinearities of each detector channel were corrected. For image reconstruction, the projection data of each source row were rebinned into a full cone beam data set, and the FDK algorithm was used. The reconstructed volumes from upper and lower source rows shared an overlap volume which was combined in image space. The images of the uniform PMMA cylinder phantom showed good uniformity and no apparent artifacts. The measured in-plane MTF showed 13 lp cm-1 at 10% cutoff, in good agreement with expectations. The rat data were also reconstructed reliably. The initial experimental results from this rotating-gantry MS-IGCT system demonstrated its ability to image a complex anatomical object without any significant image artifacts and to achieve high image resolution and large axial coverage in a single gantry rotation.

Original languageEnglish
Pages (from-to)1189-1202
Number of pages14
JournalPhysics in medicine and biology
Volume59
Issue number5
DOIs
Publication statusPublished - 2014 Mar 7

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X-Rays
Polymethyl Methacrylate
Artifacts
Tungsten
Computer-Assisted Image Processing
Information Storage and Retrieval
Calibration
Datasets

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Baek, Jongduk ; De Man, Bruno ; Uribe, Jorge ; Longtin, Randy ; Harrison, Daniel ; Reynolds, Joseph ; Neculaes, Bogdan ; Frutschy, Kristopher ; Inzinna, Louis ; Caiafa, Antonio ; Senzig, Robert ; Pelc, Norbert J. / A multi-source inverse-geometry CT system : Initial results with an 8 spot x-ray source array. In: Physics in medicine and biology. 2014 ; Vol. 59, No. 5. pp. 1189-1202.
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Baek, J, De Man, B, Uribe, J, Longtin, R, Harrison, D, Reynolds, J, Neculaes, B, Frutschy, K, Inzinna, L, Caiafa, A, Senzig, R & Pelc, NJ 2014, 'A multi-source inverse-geometry CT system: Initial results with an 8 spot x-ray source array', Physics in medicine and biology, vol. 59, no. 5, pp. 1189-1202. https://doi.org/10.1088/0031-9155/59/5/1189

A multi-source inverse-geometry CT system : Initial results with an 8 spot x-ray source array. / Baek, Jongduk; De Man, Bruno; Uribe, Jorge; Longtin, Randy; Harrison, Daniel; Reynolds, Joseph; Neculaes, Bogdan; Frutschy, Kristopher; Inzinna, Louis; Caiafa, Antonio; Senzig, Robert; Pelc, Norbert J.

In: Physics in medicine and biology, Vol. 59, No. 5, 07.03.2014, p. 1189-1202.

Research output: Contribution to journalArticle

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AU - Baek, Jongduk

AU - De Man, Bruno

AU - Uribe, Jorge

AU - Longtin, Randy

AU - Harrison, Daniel

AU - Reynolds, Joseph

AU - Neculaes, Bogdan

AU - Frutschy, Kristopher

AU - Inzinna, Louis

AU - Caiafa, Antonio

AU - Senzig, Robert

AU - Pelc, Norbert J.

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N2 - We present initial experimental results of a rotating-gantry multi-source inverse-geometry CT (MS-IGCT) system. The MS-IGCT system was built with a single module of 2 × 4 x-ray sources and a 2D detector array. It produced a 75 mm in-plane field-of-view (FOV) with 160 mm axial coverage in a single gantry rotation. To evaluate system performance, a 2.5 inch diameter uniform PMMA cylinder phantom, a 200 μm diameter tungsten wire, and a euthanized rat were scanned. Each scan acquired 125 views per source and the gantry rotation time was 1 s per revolution. Geometric calibration was performed using a bead phantom. The scanning parameters were 80 kVp, 125 mA, and 5.4 μs pulse per source location per view. A data normalization technique was applied to the acquired projection data, and beam hardening and spectral nonlinearities of each detector channel were corrected. For image reconstruction, the projection data of each source row were rebinned into a full cone beam data set, and the FDK algorithm was used. The reconstructed volumes from upper and lower source rows shared an overlap volume which was combined in image space. The images of the uniform PMMA cylinder phantom showed good uniformity and no apparent artifacts. The measured in-plane MTF showed 13 lp cm-1 at 10% cutoff, in good agreement with expectations. The rat data were also reconstructed reliably. The initial experimental results from this rotating-gantry MS-IGCT system demonstrated its ability to image a complex anatomical object without any significant image artifacts and to achieve high image resolution and large axial coverage in a single gantry rotation.

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