A multicenter study of the detection rate for prostate cancer according to the serum prostate-specific antigen level in Korean men

Dong Hyeon Lee, Won Jae Yang, Byung Ha Chung, Sun Il Kim, Se Joong Kim, Young Sig Kim, Hong Sup Kim, Do Hwan Seong, Jae Man Song, Seung Choul Yang, Sang Hyeon Cheon, In Rae Cho, Jin Seon Cho, Young Deuk Choi, Sung Joon Hong, Chun Il Kim

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Purpose: The incidence of prostate cancer is increasing in Korea, but compared with western counties, the incidence is relatively low. The detection rate of prostate cancer, according to the serum prostate-specific antigen (PSA) level, is reportedly different in Korean men, but this remains to be confirmed. We retrospectively reviewed the data of prostate biopsies, and evaluated the detection rate of prostate cancer from biopsies, according to the serum PSA level in Korean men. Materials and methods: We retrospectively reviewed the results of 2,422 Korean men who had undergone prostate biopsies at 12 medical centers. Prostate biopsies were performed in cases of high PSA levels, greater than 4ng/ml, or abnormal findings on digital rectal examination. Results: Of the 2,422 men, 39.7% had a positive biopsy. With PSA levels between 4 and 10ng/ml, the detection rate of prostate cancer was 15.9%. This rate was similar to that of the Japanese (15.8%), but quite different from that of American men (25%). With PSA levels above 10ng/ml, 59.5% of men had a positive biopsy. For PSA levels ≥4ng/ml and ≥10ng/ml, the detection rates were 42.1 and 59.5%, respectively. Conclusions: When the serum PSA levels were divided into 4 subdivisions (4.0-10.0, 10.0-20.0 and 20.0-100.0ng/ml and more than 100.0ng/ml), the detection rates were 15.9, 34.1, 66.2 and 93.8%, respectively.

Original languageEnglish
Pages (from-to)433-437
Number of pages5
JournalKorean Journal of Urology
Volume46
Issue number5
Publication statusPublished - 2005 May 1

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Prostate-Specific Antigen
Multicenter Studies
Prostatic Neoplasms
Biopsy
Serum
Prostate
Digital Rectal Examination
Incidence
Korea

All Science Journal Classification (ASJC) codes

  • Urology

Cite this

Lee, Dong Hyeon ; Yang, Won Jae ; Chung, Byung Ha ; Kim, Sun Il ; Kim, Se Joong ; Kim, Young Sig ; Kim, Hong Sup ; Seong, Do Hwan ; Song, Jae Man ; Yang, Seung Choul ; Cheon, Sang Hyeon ; Cho, In Rae ; Cho, Jin Seon ; Choi, Young Deuk ; Hong, Sung Joon ; Kim, Chun Il. / A multicenter study of the detection rate for prostate cancer according to the serum prostate-specific antigen level in Korean men. In: Korean Journal of Urology. 2005 ; Vol. 46, No. 5. pp. 433-437.
@article{09b3f0d0cf4f47d5b38534a51f8d6fcc,
title = "A multicenter study of the detection rate for prostate cancer according to the serum prostate-specific antigen level in Korean men",
abstract = "Purpose: The incidence of prostate cancer is increasing in Korea, but compared with western counties, the incidence is relatively low. The detection rate of prostate cancer, according to the serum prostate-specific antigen (PSA) level, is reportedly different in Korean men, but this remains to be confirmed. We retrospectively reviewed the data of prostate biopsies, and evaluated the detection rate of prostate cancer from biopsies, according to the serum PSA level in Korean men. Materials and methods: We retrospectively reviewed the results of 2,422 Korean men who had undergone prostate biopsies at 12 medical centers. Prostate biopsies were performed in cases of high PSA levels, greater than 4ng/ml, or abnormal findings on digital rectal examination. Results: Of the 2,422 men, 39.7{\%} had a positive biopsy. With PSA levels between 4 and 10ng/ml, the detection rate of prostate cancer was 15.9{\%}. This rate was similar to that of the Japanese (15.8{\%}), but quite different from that of American men (25{\%}). With PSA levels above 10ng/ml, 59.5{\%} of men had a positive biopsy. For PSA levels ≥4ng/ml and ≥10ng/ml, the detection rates were 42.1 and 59.5{\%}, respectively. Conclusions: When the serum PSA levels were divided into 4 subdivisions (4.0-10.0, 10.0-20.0 and 20.0-100.0ng/ml and more than 100.0ng/ml), the detection rates were 15.9, 34.1, 66.2 and 93.8{\%}, respectively.",
author = "Lee, {Dong Hyeon} and Yang, {Won Jae} and Chung, {Byung Ha} and Kim, {Sun Il} and Kim, {Se Joong} and Kim, {Young Sig} and Kim, {Hong Sup} and Seong, {Do Hwan} and Song, {Jae Man} and Yang, {Seung Choul} and Cheon, {Sang Hyeon} and Cho, {In Rae} and Cho, {Jin Seon} and Choi, {Young Deuk} and Hong, {Sung Joon} and Kim, {Chun Il}",
year = "2005",
month = "5",
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language = "English",
volume = "46",
pages = "433--437",
journal = "Korean Journal of Urology",
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Lee, DH, Yang, WJ, Chung, BH, Kim, SI, Kim, SJ, Kim, YS, Kim, HS, Seong, DH, Song, JM, Yang, SC, Cheon, SH, Cho, IR, Cho, JS, Choi, YD, Hong, SJ & Kim, CI 2005, 'A multicenter study of the detection rate for prostate cancer according to the serum prostate-specific antigen level in Korean men', Korean Journal of Urology, vol. 46, no. 5, pp. 433-437.

A multicenter study of the detection rate for prostate cancer according to the serum prostate-specific antigen level in Korean men. / Lee, Dong Hyeon; Yang, Won Jae; Chung, Byung Ha; Kim, Sun Il; Kim, Se Joong; Kim, Young Sig; Kim, Hong Sup; Seong, Do Hwan; Song, Jae Man; Yang, Seung Choul; Cheon, Sang Hyeon; Cho, In Rae; Cho, Jin Seon; Choi, Young Deuk; Hong, Sung Joon; Kim, Chun Il.

In: Korean Journal of Urology, Vol. 46, No. 5, 01.05.2005, p. 433-437.

Research output: Contribution to journalReview article

TY - JOUR

T1 - A multicenter study of the detection rate for prostate cancer according to the serum prostate-specific antigen level in Korean men

AU - Lee, Dong Hyeon

AU - Yang, Won Jae

AU - Chung, Byung Ha

AU - Kim, Sun Il

AU - Kim, Se Joong

AU - Kim, Young Sig

AU - Kim, Hong Sup

AU - Seong, Do Hwan

AU - Song, Jae Man

AU - Yang, Seung Choul

AU - Cheon, Sang Hyeon

AU - Cho, In Rae

AU - Cho, Jin Seon

AU - Choi, Young Deuk

AU - Hong, Sung Joon

AU - Kim, Chun Il

PY - 2005/5/1

Y1 - 2005/5/1

N2 - Purpose: The incidence of prostate cancer is increasing in Korea, but compared with western counties, the incidence is relatively low. The detection rate of prostate cancer, according to the serum prostate-specific antigen (PSA) level, is reportedly different in Korean men, but this remains to be confirmed. We retrospectively reviewed the data of prostate biopsies, and evaluated the detection rate of prostate cancer from biopsies, according to the serum PSA level in Korean men. Materials and methods: We retrospectively reviewed the results of 2,422 Korean men who had undergone prostate biopsies at 12 medical centers. Prostate biopsies were performed in cases of high PSA levels, greater than 4ng/ml, or abnormal findings on digital rectal examination. Results: Of the 2,422 men, 39.7% had a positive biopsy. With PSA levels between 4 and 10ng/ml, the detection rate of prostate cancer was 15.9%. This rate was similar to that of the Japanese (15.8%), but quite different from that of American men (25%). With PSA levels above 10ng/ml, 59.5% of men had a positive biopsy. For PSA levels ≥4ng/ml and ≥10ng/ml, the detection rates were 42.1 and 59.5%, respectively. Conclusions: When the serum PSA levels were divided into 4 subdivisions (4.0-10.0, 10.0-20.0 and 20.0-100.0ng/ml and more than 100.0ng/ml), the detection rates were 15.9, 34.1, 66.2 and 93.8%, respectively.

AB - Purpose: The incidence of prostate cancer is increasing in Korea, but compared with western counties, the incidence is relatively low. The detection rate of prostate cancer, according to the serum prostate-specific antigen (PSA) level, is reportedly different in Korean men, but this remains to be confirmed. We retrospectively reviewed the data of prostate biopsies, and evaluated the detection rate of prostate cancer from biopsies, according to the serum PSA level in Korean men. Materials and methods: We retrospectively reviewed the results of 2,422 Korean men who had undergone prostate biopsies at 12 medical centers. Prostate biopsies were performed in cases of high PSA levels, greater than 4ng/ml, or abnormal findings on digital rectal examination. Results: Of the 2,422 men, 39.7% had a positive biopsy. With PSA levels between 4 and 10ng/ml, the detection rate of prostate cancer was 15.9%. This rate was similar to that of the Japanese (15.8%), but quite different from that of American men (25%). With PSA levels above 10ng/ml, 59.5% of men had a positive biopsy. For PSA levels ≥4ng/ml and ≥10ng/ml, the detection rates were 42.1 and 59.5%, respectively. Conclusions: When the serum PSA levels were divided into 4 subdivisions (4.0-10.0, 10.0-20.0 and 20.0-100.0ng/ml and more than 100.0ng/ml), the detection rates were 15.9, 34.1, 66.2 and 93.8%, respectively.

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M3 - Review article

AN - SCOPUS:20344377854

VL - 46

SP - 433

EP - 437

JO - Korean Journal of Urology

JF - Korean Journal of Urology

SN - 2005-6737

IS - 5

ER -